Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0512 | 0.5 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0512 | 0.5 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0512 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0512 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0512 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0512 | 0.5 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0512 | 0.5 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0512 | 0.5 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0512 | 0.5 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0512 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0512 | 0.5 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0512 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Effect (functional) | = 10 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 0 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 10 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 0 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 33.8 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 100 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 33.8 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 100 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 40 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 10 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 40 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 10 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 44.9 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 0.4 ug/day with estrone | ChEMBL. | 6308256 |
Effect (functional) | = 44.9 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 1000 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 44.9 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 0.4 ug/day with estrone | ChEMBL. | 6308256 |
Effect (functional) | = 44.9 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 1000 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 48.7 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 1 ug/day | ChEMBL. | 6308256 |
Effect (functional) | = 48.7 mg 100g-1 | Estrogenic activity in uterotrophic assay in mice at 1 ug/day | ChEMBL. | 6308256 |
RBA (binding) | = 8.1 | Relative binding affinity for calf uterine estrogen receptor by 17-beta-[3H]-estradiol competition. | ChEMBL. | 6308256 |
RBA (binding) | = 8.1 | Relative binding affinity for calf uterine estrogen receptor is the ratio of molar cencentrations of 17-beta-estradiol and compound required to decrease amount of bound [3H]-E2 by 50% X 100. | ChEMBL. | 6325689 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.