Detailed information for compound 1474777

Basic information

Technical information
  • TDR Targets ID: 1474777
  • Name: 4-(phenylmethyl)benzo[f]quinolin-4-ium
  • MW: 270.348 | Formula: C20H16N+
  • H donors: 0 H acceptors: 0 LogP: 5.17 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)C[n+]1cccc2c1ccc1c2cccc1
  • InChi: 1S/C20H16N/c1-2-7-16(8-3-1)15-21-14-6-11-19-18-10-5-4-9-17(18)12-13-20(19)21/h1-14H,15H2/q+1
  • InChiKey: CYTLIRHZWTZJIZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-(benzyl)benzo[f]quinolin-4-ium
  • ZINC03153795
  • BAS 00226818

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei beta tubulin 0.1379 0.8166 1
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0162 0.0858 0.1043
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0051 0.0055
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0118 0.0145
Giardia lamblia Alpha-tubulin 0.1046 0.6167 0.7552
Schistosoma mansoni smad1 5 8 and 0.0067 0.0287 0.031
Plasmodium falciparum histone deacetylase, putative 0.0255 0.1413 0.1723
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0115 0.0606
Onchocerca volvulus 0.0039 0.0115 0.0384
Schistosoma mansoni tubulin subunit beta 0.1379 0.8166 0.8797
Schistosoma mansoni histone deacetylase 1 2 3 0.0161 0.085 0.0916
Entamoeba histolytica tubulin family protein 0.1379 0.8166 1
Schistosoma mansoni smad 0.0067 0.0287 0.031
Brugia malayi bZIP transcription factor family protein 0.009 0.0424 0.052
Schistosoma mansoni hypothetical protein 0.1565 0.9283 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0073 0.0081
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0129 0.0656 0.3445
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.1046 0.6167 0.7552
Loa Loa (eye worm) hypothetical protein 0.0608 0.3535 0.4329
Echinococcus granulosus transcription factor eb 0.0116 0.0579 0.0623
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Schistosoma mansoni chromobox protein 0.0075 0.0332 0.0358
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0116 0.0578 0.2988
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0131 0.0668 0.0818
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0162 0.0858 0.1043
Onchocerca volvulus Bile acid receptor homolog 0.0136 0.0701 0.2456
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0238 0.0257
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0136 0.0701 0.0755
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0013 0.0023
Plasmodium falciparum tubulin beta chain 0.1379 0.8166 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0136 0.0701 0.0755
Echinococcus multilocularis muscleblind protein 0.031 0.1747 0.1747
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0007 0.0008
Echinococcus granulosus CREB binding protein 0.0116 0.0581 0.0626
Echinococcus multilocularis tubulin alpha chain 0.1046 0.6167 0.6167
Brugia malayi nuclear hormone receptor 0.0062 0.0255 0.0312
Echinococcus granulosus beta tubulin 0.1379 0.8166 0.8797
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Schistosoma mansoni ap endonuclease 0.0039 0.0118 0.0127
Loa Loa (eye worm) tubulin alpha 2 0.071 0.4147 0.5078
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0115 0.0141
Brugia malayi nuclear hormone receptor family member nhr-6 0.0062 0.0255 0.0312
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Echinococcus multilocularis transcription factor eb 0.0116 0.0579 0.0579
Echinococcus granulosus thyroid hormone receptor alpha 0.0062 0.0255 0.0274
Toxoplasma gondii exonuclease III APE 0.0039 0.0118 0.0137
Loa Loa (eye worm) hypothetical protein 0.0464 0.2667 0.3266
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0136 0.0701 0.0755
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0115 0.0141
Mycobacterium ulcerans lipase LipD 0.0039 0.0115 0.0606
Mycobacterium tuberculosis Conserved protein 0.0039 0.0115 0.0606
Loa Loa (eye worm) hypothetical protein 0.03 0.1684 0.2062
Toxoplasma gondii endonuclease IV APN 0.0082 0.0377 0.0454
Leishmania major trypanothione reductase 0.0051 0.0188 0.023
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0491 0.0601
Schistosoma mansoni CREB-binding protein 2 0.0116 0.0581 0.0626
Loa Loa (eye worm) hypothetical protein 0.0094 0.0446 0.0546
Brugia malayi MH1 domain containing protein 0.0037 0.0107 0.0131
Schistosoma mansoni intermediate filament proteins 0.0056 0.022 0.0237
Echinococcus multilocularis FTZ F1 alpha 0.0136 0.0701 0.0701
Leishmania major hypothetical protein, conserved 0.0021 0.0007 0.0008
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0039 0.0118 0.0145
Toxoplasma gondii histone deacetylase HDAC1 0.0255 0.1413 0.1723
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.0238 0.0238
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0073 0.0089
Brugia malayi Cell division protein ftsZ 0.0336 0.1904 0.2331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0136 0.0701 0.0859
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0249 0.0305
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.0255 0.0255
Schistosoma mansoni tubulin subunit epsilon 0.0775 0.4536 0.4887
Schistosoma mansoni tubulin subunit alpha 0.0336 0.1904 0.2051
Echinococcus granulosus lamin 0.0056 0.022 0.0237
Leishmania major hypothetical protein, conserved 0.0039 0.0115 0.0141
Brugia malayi MH2 domain containing protein 0.0067 0.0287 0.0352
Brugia malayi nuclear receptor NHR-88 0.0136 0.0701 0.0859
Echinococcus granulosus tumor protein p63 0.0702 0.4099 0.4416
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0047 0.0166 0.0871
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0136 0.0701 0.0755
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0007 0.0008
Onchocerca volvulus 0.0103 0.0501 0.1746
Echinococcus granulosus Tubulin beta 2C chain 0.1379 0.8166 0.8797
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0168 0.089 0.089
Schistosoma mansoni tubulin subunit beta 0.1379 0.8166 0.8797
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0049
Mycobacterium tuberculosis Conserved protein 0.0039 0.0115 0.0606
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0092 0.0434 0.0531
Brugia malayi hypoxia-induced factor 1 0.0161 0.0853 0.1045
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0188 0.0203
Echinococcus granulosus single minded 2 0.0039 0.0115 0.0124
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0073 0.0089
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0007 0.0008
Leishmania major gamma-tubulin 0.0775 0.4536 0.5555
Trichomonas vaginalis tubulin epsilon chain, putative 0.1379 0.8166 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0067 0.0287 0.0352
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0136 0.0701 0.0859
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0584 0.0715
Echinococcus granulosus beta tubulin 0.1379 0.8166 0.8797
Leishmania major delta tubulin, putative 0.0336 0.1904 0.2331
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0116 0.0578 0.3037
Echinococcus multilocularis tubulin alpha 1C chain 0.1046 0.6167 0.6167
Loa Loa (eye worm) hypothetical protein 0.0026 0.004 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0135 0.0165
Echinococcus granulosus tubulin alpha 1C chain 0.1046 0.6167 0.6644
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0062 0.0255 0.0312
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0076 0.0093
Echinococcus granulosus intermediate filament protein 0.0056 0.022 0.0237
Echinococcus multilocularis tubulin subunit TubB 0.1046 0.6167 0.6167
Trichomonas vaginalis conserved hypothetical protein 0.0336 0.1904 0.2331
Onchocerca volvulus 0.0062 0.0255 0.0877
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0701 0.0859
Brugia malayi tubulin alpha-2 chain 0.1046 0.6167 0.7552
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0092 0.0434 0.0523
Onchocerca volvulus 0.0491 0.2834 1
Brugia malayi Nuclear hormone receptor-like 1 0.0074 0.033 0.0404
Schistosoma mansoni tubulin subunit alpha 0.1046 0.6167 0.6644
Plasmodium falciparum histone deacetylase 1 0.0464 0.2667 0.3261
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0082
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0064 0.0078
Entamoeba histolytica acetyltransferase, GNAT family 0.0082 0.0377 0.0462
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0116 0.0578 0.3037
Plasmodium vivax histone deacetylase 2, putative 0.0255 0.1413 0.1723
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0092 0.0434 0.0523
Brugia malayi hypothetical protein 0.0062 0.0255 0.0312
Trichomonas vaginalis tubulin beta chain, putative 0.0438 0.2516 0.3081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0459 0.0495
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0073 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0336 0.1904 0.2331
Onchocerca volvulus 0.0056 0.022 0.0754
Onchocerca volvulus 0.03 0.1684 0.5932
Schistosoma mansoni lamin 0.0056 0.022 0.0237
Echinococcus granulosus histone deacetylase 0.0255 0.1413 0.1522
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0062 0.0255 0.0312
Trichomonas vaginalis esterase, putative 0.0039 0.0115 0.0141
Echinococcus granulosus smad 0.0067 0.0287 0.031
Echinococcus multilocularis hypothetical protein 0.1046 0.6167 0.6167
Trichomonas vaginalis tubulin alpha chain, putative 0.0438 0.2516 0.3081
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0701 0.0859
Brugia malayi MH1 domain containing protein 0.0067 0.0287 0.0352
Loa Loa (eye worm) hypothetical protein 0.0039 0.0115 0.0141
Loa Loa (eye worm) nuclear receptor NHR-67 0.0062 0.0255 0.0312
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0039 0.0118 0.0621
Brugia malayi follicle stimulating hormone receptor 0.0256 0.142 0.1739
Trichomonas vaginalis histone deacetylase, putative 0.0464 0.2667 0.3266
Brugia malayi Heterochromatin protein 1 0.0075 0.0332 0.0407
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.0007 0.0008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0701 0.0701
Loa Loa (eye worm) alpha-tubulin 0.1046 0.6167 0.7552
Echinococcus granulosus GPCR family 2 0.0032 0.0076 0.0082
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0255 0.0274
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.0584 0.0715
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0039 0.0118 0.0118
Schistosoma mansoni tubulin subunit beta 0.1379 0.8166 0.8797
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0074 0.033 0.0404
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0073 0.0089
Brugia malayi histone deacetylase 3 (HD3) 0.0464 0.2667 0.3266
Loa Loa (eye worm) MH1 domain-containing protein 0.003 0.0064 0.0078
Trichomonas vaginalis tubulin epsilon chain, putative 0.1046 0.6167 0.7552
Giardia lamblia Beta tubulin 0.1379 0.8166 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0092 0.0434 0.0523
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0136 0.0701 0.0701
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0073 0.0081
Leishmania major hypothetical protein, conserved 0.0021 0.0007 0.0008
Trypanosoma brucei epsilon tubulin 0.0775 0.4536 0.5555
Onchocerca volvulus 0.0056 0.022 0.0754
Leishmania major beta tubulin 0.1379 0.8166 1
Echinococcus granulosus flap endonuclease 1 0.0028 0.0051 0.0055
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0067 0.0287 0.0287
Loa Loa (eye worm) hypothetical protein 0.0056 0.022 0.0269
Loa Loa (eye worm) MH2 domain-containing protein 0.003 0.0064 0.0078
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0007 0.0008
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0067 0.0287 0.031
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0136 0.0701 0.2456
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0007 0.0007
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0608 0.3535 0.4329
Leishmania major beta tubulin 0.1379 0.8166 1
Loa Loa (eye worm) thymidylate synthase 0.0115 0.0576 0.0705
Trypanosoma brucei beta tubulin 0.1379 0.8166 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0136 0.0701 0.0755
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0039 0.0118 0.0145
Echinococcus granulosus histone deacetylase 6 0.0255 0.1413 0.1522
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0007 0.0008
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0047 0.0166 0.0806
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0131 0.0668 0.0668
Schistosoma mansoni histone deacetylase hda2 0.0161 0.085 0.0916
Echinococcus multilocularis histone deacetylase 3 0.0464 0.2667 0.2667
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0051 0.0063
Schistosoma mansoni tubulin subunit beta 0.1379 0.8166 0.8797
Brugia malayi thymidylate synthase 0.0115 0.0576 0.0705
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0039 0.0118 0.0145
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.009 0.0424 0.0424
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0073 0.0081
Echinococcus granulosus neuropeptide s receptor 0.0503 0.2901 0.3125
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0584 0.0715
Mycobacterium tuberculosis Hypothetical protein 0.0055 0.0213 0.1118
Trichomonas vaginalis tubulin beta chain, putative 0.1046 0.6167 0.7552
Echinococcus granulosus Tubulin alpha 1 chain 0.1046 0.6167 0.6644
Trypanosoma cruzi tubulin gamma chain 0.0775 0.4536 0.5555
Brugia malayi Histone deacetylase family protein 0.0255 0.1413 0.173
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0131 0.0668 0.0818
Brugia malayi nuclear receptor NHR-67 0.0062 0.0255 0.0312
Echinococcus granulosus muscleblind protein 0.031 0.1747 0.1882
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0021 0.0007 0.0007
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0052 0.0064
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0021 0.0007 0.0007
Echinococcus multilocularis Tubulin alpha 1 chain 0.1046 0.6167 0.6167
Echinococcus granulosus tubulin beta 4A class IVa 0.1379 0.8166 0.8797
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0116 0.0581 0.0626
Trypanosoma cruzi histone deacetylase, putative 0.0255 0.1413 0.173
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0584 0.0715
Brugia malayi hypothetical protein 0.03 0.1684 0.2062
Trichomonas vaginalis tubulin beta chain, putative 0.1379 0.8166 1
Trypanosoma cruzi histone deacetylase, putative 0.0255 0.1413 0.173
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0584 0.0715
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.1228 0.1504
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.008 0.009
Echinococcus granulosus tubulin alpha chain 0.1046 0.6167 0.6644
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0459 0.0563
Brugia malayi conserved hypotetical protein 0.0062 0.0255 0.0312
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0047 0.0166 0.0871
Plasmodium vivax histone deacetylase, putative 0.0161 0.085 0.1034
Brugia malayi Histone deacetylase family protein 0.0255 0.1413 0.173
Schistosoma mansoni flap endonuclease-1 0.0025 0.0035 0.0038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0297 0.1669 0.1669
Brugia malayi chromobox protein homolog 3 0.0042 0.0135 0.0165
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0154 0.0189
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0131 0.0668 0.081
Loa Loa (eye worm) hypothetical protein 0.0074 0.033 0.0404
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0584 0.0715
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1379 0.8166 0.8166
Echinococcus multilocularis tubulin epsilon chain 0.0775 0.4536 0.4536
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0076 0.0082
Plasmodium falciparum histone acetyltransferase GCN5 0.0082 0.0377 0.0454
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0464 0.2667 0.3266
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0082
Echinococcus granulosus neuropeptide receptor A26 0.0503 0.2901 0.3125
Mycobacterium ulcerans hypothetical protein 0.0022 0.0013 0.007
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0118 0.0137
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Trypanosoma brucei zeta tubulin 0.0336 0.1904 0.2331
Loa Loa (eye worm) hypothetical protein 0.003 0.0064 0.0078
Loa Loa (eye worm) hypothetical protein 0.1046 0.6167 0.7552
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0701 0.0701
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0021 0.0007 0.0008
Loa Loa (eye worm) histone deacetylase 11 0.0161 0.085 0.1041
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0648 0.0786
Echinococcus granulosus tubulin alpha chain 0.1046 0.6167 0.6644
Echinococcus granulosus mothers against decapentaplegic 5 0.0067 0.0287 0.031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.0297 0.0356
Trichomonas vaginalis tubulin epsilon chain, putative 0.1046 0.6167 0.7552
Leishmania major beta tubulin 0.1379 0.8166 1
Brugia malayi isocitrate dehydrogenase 0.0131 0.0668 0.0818
Echinococcus granulosus Smad4 0.0067 0.0287 0.031
Echinococcus multilocularis neuropeptide receptor A26 0.0503 0.2901 0.2901
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.0336 0.1904 1
Plasmodium falciparum alpha tubulin 2 0.1046 0.6167 0.755
Trypanosoma brucei alpha tubulin 0.1046 0.6167 0.7552
Leishmania major beta tubulin 0.1379 0.8166 1
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0299 0.0366
Onchocerca volvulus 0.0071 0.0308 0.1066
Brugia malayi beta-lactamase 0.0039 0.0115 0.0141
Brugia malayi Tubulin alpha chain 0.0336 0.1904 0.2331
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0701 0.0859
Leishmania major beta tubulin 0.1379 0.8166 1
Brugia malayi Pax transcription factor protein 2 0.0491 0.2834 0.3471
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0115 0.054
Echinococcus multilocularis chromobox protein 1 0.0075 0.0332 0.0332
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0136 0.0701 0.0755
Mycobacterium tuberculosis Probable reductase 0.0116 0.0578 0.3037
Trypanosoma brucei beta tubulin 0.1379 0.8166 1
Loa Loa (eye worm) tubulin gamma chain 0.0775 0.4536 0.5555
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0501 0.0539
Echinococcus multilocularis histone deacetylase 7 0.0255 0.1413 0.1413
Loa Loa (eye worm) hypothetical protein 0.0069 0.0299 0.0366
Schistosoma mansoni alpha tubulin 0.1046 0.6167 0.6644
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0115 0.0606
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.008 0.008
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0459 0.0563
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0013 0.0016
Loa Loa (eye worm) hypothetical protein 0.0088 0.041 0.0502
Leishmania major histone deacetylase, putative 0.0464 0.2667 0.3266
Echinococcus multilocularis mothers against decapentaplegic 2 0.003 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0022 0.0013 0.0016
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0131 0.0668 0.0818
Echinococcus multilocularis neuropeptide s receptor 0.0503 0.2901 0.2901
Brugia malayi bHLH-PAS transcription factor 0.0039 0.0115 0.0141
Brugia malayi Tubulin beta-1 chain 0.1379 0.8166 1
Echinococcus granulosus tubulin subunit TubB 0.1046 0.6167 0.6644
Mycobacterium leprae cell division protein FtsZ 0.0336 0.1904 1
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0051 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0062 0.0255 0.0274
Loa Loa (eye worm) hypothetical protein 0.0027 0.0046 0.0056
Leishmania major histone deacetylase, putative 0.0255 0.1413 0.173
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.0255 0.0877
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0115 0.0124
Trichomonas vaginalis tubulin epsilon chain, putative 0.1379 0.8166 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0377 0.0462
Onchocerca volvulus TPPP family protein homolog 0.0392 0.224 0.79
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0701 0.0755
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0584 0.0715
Mycobacterium ulcerans beta-lactamase 0.0039 0.0115 0.0606
Loa Loa (eye worm) hypothetical protein 0.0074 0.033 0.0404
Schistosoma mansoni alpha tubulin 0.1046 0.6167 0.6644
Brugia malayi nuclear receptor RXR 0.0074 0.033 0.0404
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0256 0.142 0.1739
Brugia malayi hypothetical protein 0.0175 0.0935 0.1145
Echinococcus multilocularis histone deacetylase 6 0.0275 0.1536 0.1536
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0007 0.0007
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0136 0.0701 0.0755
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0136 0.0701 0.0859
Trichomonas vaginalis tubulin beta chain, putative 0.1046 0.6167 0.7552
Schistosoma mansoni hypothetical protein 0.0297 0.1669 0.1798
Trichomonas vaginalis histone deacetylase, putative 0.0464 0.2667 0.3266
Loa Loa (eye worm) hypothetical protein 0.0074 0.033 0.0404
Schistosoma mansoni Smad4 0.003 0.0064 0.0069
Echinococcus granulosus histone deacetylase 3 0.0464 0.2667 0.2873
Brugia malayi Dihydrofolate reductase 0.0047 0.0166 0.0203
Echinococcus granulosus nuclear receptor nhr 48 0.0062 0.0255 0.0274
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0073 0.0089
Brugia malayi PAS domain containing protein 0.0052 0.0197 0.0241
Brugia malayi tubulin alpha chain - mouse 0.1046 0.6167 0.7552
Trypanosoma cruzi tubulin delta chain 0.0336 0.1904 0.2331
Onchocerca volvulus 0.0039 0.0119 0.0396
Echinococcus multilocularis Tubulin beta 2C chain 0.1379 0.8166 0.8166
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0115 0.0606
Loa Loa (eye worm) hypothetical protein 0.0161 0.085 0.1041
Echinococcus multilocularis Tubulin beta 2C chain 0.1379 0.8166 0.8166
Trypanosoma cruzi tubulin delta chain 0.0336 0.1904 0.2331
Plasmodium vivax SET domain protein, putative 0.0033 0.008 0.009
Echinococcus multilocularis tubulin alpha 3 chain 0.1046 0.6167 0.6167
Echinococcus multilocularis tubulin alpha chain 0.1046 0.6167 0.6167
Loa Loa (eye worm) tubulin alpha-2 chain 0.1046 0.6167 0.7552
Loa Loa (eye worm) alpha-tubulin isotype 2 0.071 0.4147 0.5078
Brugia malayi hypothetical protein 0.0074 0.033 0.0404
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.008 0.0086
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0021 0.0007 0.0007
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0464 0.2667 0.3266
Schistosoma mansoni aryl hydrocarbon receptor 0.0053 0.02 0.0216
Schistosoma mansoni coup transcription factor 0.0136 0.0701 0.0755
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.0584 0.3017
Brugia malayi Muscleblind-like protein 0.031 0.1747 0.214
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0584 0.0629
Echinococcus multilocularis tubulin alpha chain 0.1046 0.6167 0.6167
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0052 0.0064
Echinococcus granulosus tubulin delta chain 0.0336 0.1904 0.2051
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0076 0.0076
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.0584 0.0584
Echinococcus multilocularis beta tubulin 0.1379 0.8166 0.8166
Echinococcus multilocularis thyroid hormone receptor alpha 0.0271 0.1512 0.1512
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0007 0.0008
Loa Loa (eye worm) tubulin beta chain 0.1379 0.8166 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0062 0.0255 0.0274
Toxoplasma gondii histone deacetylase HDAC4 0.0161 0.085 0.1034
Schistosoma mansoni hypothetical protein 0.0106 0.0518 0.0558
Echinococcus granulosus TGF beta signal transducer SmadC 0.0067 0.0287 0.031
Loa Loa (eye worm) alpha-tubulin 0.1046 0.6167 0.7552
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0136 0.0701 0.0859
Brugia malayi Intermediate filament tail domain containing protein 0.0056 0.022 0.0269
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0062 0.0075
Echinococcus multilocularis smad 0.0067 0.0287 0.0287
Brugia malayi dihydrofolate reductase family protein 0.0047 0.0166 0.0203
Trypanosoma cruzi alpha tubulin, putative 0.1046 0.6167 0.7552
Brugia malayi Thioredoxin reductase 0.0051 0.0188 0.023
Brugia malayi tailless protein 0.0062 0.0255 0.0312
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Plasmodium falciparum tubulin epsilon chain, putative 0.0775 0.4536 0.5551
Leishmania major beta tubulin 0.1379 0.8166 1
Schistosoma mansoni hypothetical protein 0.0057 0.0227 0.0244
Entamoeba histolytica tubulin family protein 0.1379 0.8166 1
Plasmodium falciparum glutathione reductase 0.0051 0.0188 0.0222
Trypanosoma cruzi epsilon tubulin, putative 0.0775 0.4536 0.5555
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0154 0.0521
Echinococcus granulosus Tubulin beta 2C chain 0.1379 0.8166 0.8797
Leishmania major beta tubulin 0.1379 0.8166 1
Brugia malayi beta-lactamase family protein 0.0039 0.0115 0.0141
Mycobacterium tuberculosis Probable oxidoreductase 0.0129 0.0656 0.3445
Leishmania major beta tubulin 0.1379 0.8166 1
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.0584 0.0629
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Loa Loa (eye worm) BEN-1 protein 0.1379 0.8166 1
Brugia malayi hypothetical protein 0.0062 0.0255 0.0312
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0039 0.0118 0.0127
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0136 0.0701 0.0859
Brugia malayi MH2 domain containing protein 0.003 0.0064 0.0078
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0115 0.0606
Echinococcus multilocularis Tubulin beta 2C chain 0.1379 0.8166 0.8166
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0057 0.0227 0.0244
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Echinococcus granulosus Tubulin alpha 1 chain 0.1046 0.6167 0.6644
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0136 0.0701 0.0859
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0074 0.033 0.0356
Echinococcus granulosus tubulin gamma 1 chain 0.0775 0.4536 0.4887
Echinococcus granulosus geminin 0.1565 0.9283 1
Echinococcus multilocularis histone deacetylase 6 0.0255 0.1413 0.1413
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0648 0.0794
Brugia malayi Cytochrome P450 family protein 0.0028 0.0052 0.0064
Trypanosoma cruzi epsilon tubulin, putative 0.0775 0.4536 0.5555
Trypanosoma brucei PAB1-binding protein , putative 0.0127 0.0648 0.0794
Schistosoma mansoni dihydrofolate reductase 0.0047 0.0166 0.0179
Leishmania major hypothetical protein, conserved 0.0127 0.0648 0.0794
Brugia malayi Flap endonuclease-1 0.0028 0.0051 0.0063
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0021 0.0007 0.0007
Brugia malayi TAZ zinc finger family protein 0.0116 0.0581 0.0712
Giardia lamblia Gamma tubulin 0.0775 0.4536 0.5555
Trichomonas vaginalis tubulin gamma chain, putative 0.0336 0.1904 0.2331
Loa Loa (eye worm) tubulin alpha chain 0.1046 0.6167 0.7552
Brugia malayi mothers against decapentaplegic homolog 3 0.003 0.0064 0.0078
Echinococcus multilocularis tubulin alpha chain 0.1046 0.6167 0.6167
Trichomonas vaginalis tubulin, putative 0.0336 0.1904 0.2331
Loa Loa (eye worm) tubulin beta-2A chain 0.1379 0.8166 1
Echinococcus granulosus tubulin alpha 3 chain 0.1046 0.6167 0.6644
Brugia malayi Nuclear hormone receptor E75 0.0062 0.0255 0.0312
Mycobacterium tuberculosis Conserved protein 0.0039 0.0115 0.0606
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0051 0.0063
Trichomonas vaginalis ap endonuclease, putative 0.0039 0.0118 0.0145
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0115 0.0606
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0136 0.0701 0.0859
Toxoplasma gondii histone deacetylase HDAC3 0.0464 0.2667 0.3261
Loa Loa (eye worm) hypothetical protein 0.0103 0.0501 0.0613
Echinococcus multilocularis chromobox protein 1 0.0075 0.0332 0.0332
Schistosoma mansoni cpg binding protein 0.0033 0.0079 0.0085
Echinococcus granulosus alpha tubulin 0.1046 0.6167 0.6644
Brugia malayi MH2 domain containing protein 0.0067 0.0287 0.0352
Echinococcus granulosus tubulin subunit beta 0.1379 0.8166 0.8797
Brugia malayi Nuclear hormone receptor-like 1 0.0136 0.0701 0.0859
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0162 0.0858 0.105
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0377 0.0454
Echinococcus multilocularis tubulin alpha chain 0.1046 0.6167 0.6167
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0021 0.0007 0.0007
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0021 0.0007 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0136 0.0701 0.0859
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0055 0.0213 0.0261
Echinococcus multilocularis nuclear receptor nhr 48 0.0062 0.0255 0.0255
Echinococcus granulosus tubulin alpha chain 0.1046 0.6167 0.6644
Loa Loa (eye worm) hypothetical protein 0.0114 0.0569 0.0697
Entamoeba histolytica tubulin gamma chain 0.0775 0.4536 0.5555
Trichomonas vaginalis tubulin gamma chain, putative 0.1379 0.8166 1
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0131 0.0668 0.0818
Giardia lamblia Delta tubulin 0.0336 0.1904 0.2331
Echinococcus multilocularis histone deacetylase 1 0.0464 0.2667 0.2667
Brugia malayi CXXC zinc finger family protein 0.0031 0.0068 0.0084
Trypanosoma cruzi histone deacetylase, putative 0.0161 0.085 0.1041
Loa Loa (eye worm) p25-alpha family protein 0.0392 0.224 0.2744
Echinococcus granulosus Tubulin beta 2C chain 0.1379 0.8166 0.8797
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0131 0.0668 0.0668
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0129 0.0656 0.3398
Trypanosoma brucei tubulin gamma chain 0.0775 0.4536 0.5555
Brugia malayi Steroid receptor seven-up type 2 0.0136 0.0701 0.0859
Brugia malayi alpha-tubulin 0.1046 0.6167 0.7552
Echinococcus multilocularis tumor protein p63 0.0702 0.4099 0.4099
Echinococcus multilocularis geminin 0.1565 0.9283 0.9283
Loa Loa (eye worm) hypothetical protein 0.0101 0.0491 0.0601
Loa Loa (eye worm) histone deacetylase 0.0255 0.1413 0.173
Entamoeba histolytica histone deacetylase, putative 0.0464 0.2667 0.3266
Brugia malayi glutathione reductase 0.0051 0.0188 0.023
Giardia lamblia Hypothetical protein 0.0021 0.0007 0.0008
Echinococcus granulosus histone deacetylase 6 0.0275 0.1536 0.1655
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0052 0.0064
Loa Loa (eye worm) histone deacetylase 1 0.0464 0.2667 0.3266
Brugia malayi hypothetical protein 0.0082 0.0377 0.0462
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0249 0.0268
Trypanosoma brucei tubulin delta chain 0.0336 0.1904 0.2331
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0213 0.0261
Trichomonas vaginalis tubulin gamma chain, putative 0.0775 0.4536 0.5555
Brugia malayi hypothetical protein 0.0297 0.1669 0.2044
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0438 0.2516 0.3081
Brugia malayi jmjC domain containing protein 0.0061 0.0249 0.0305
Mycobacterium tuberculosis Cell division protein FtsZ 0.0336 0.1904 1
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Loa Loa (eye worm) hypothetical protein 0.0033 0.008 0.0098
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0464 0.2667 0.3266
Brugia malayi Cytochrome P450 family protein 0.0028 0.0052 0.0064
Schistosoma mansoni Smad4 0.0067 0.0287 0.031
Mycobacterium ulcerans putative regulatory protein 0.0039 0.0115 0.0606
Schistosoma mansoni histone deacetylase 4 5 0.0255 0.1413 0.1522
Loa Loa (eye worm) beta-lactamase 0.0039 0.0115 0.0141
Toxoplasma gondii isocitrate dehydrogenase 0.0131 0.0668 0.081
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0136 0.0701 0.0859
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0115 0.0141
Giardia lamblia Beta tubulin 0.1379 0.8166 1
Toxoplasma gondii alpha tubulin TUBA1 0.1046 0.6167 0.755
Chlamydia trachomatis dihydrofolate reductase 0.0047 0.0166 0.3056
Loa Loa (eye worm) Smad1 0.0067 0.0287 0.0352
Toxoplasma gondii alpha-tubulin I, putative 0.1046 0.6167 0.755
Schistosoma mansoni smad1 5 8 and 0.0067 0.0287 0.031
Loa Loa (eye worm) hypothetical protein 0.031 0.1747 0.214
Trypanosoma brucei trypanothione reductase 0.0051 0.0188 0.023
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0039 0.0118 0.0145
Giardia lamblia Histone deacetylase 0.0464 0.2667 0.3266
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0188 0.0988
Brugia malayi acetyltransferase, GNAT family protein 0.0307 0.1727 0.2115
Loa Loa (eye worm) tubulin alpha-3 chain 0.0608 0.3535 0.4329
Brugia malayi hypothetical protein 0.0127 0.0648 0.0794
Trichomonas vaginalis tubulin beta chain, putative 0.1046 0.6167 0.7552
Brugia malayi orphan nuclear receptor NR2E1 0.0062 0.0255 0.0312
Plasmodium falciparum tubulin gamma chain 0.0775 0.4536 0.5551
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0459 0.0459
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0052 0.0064
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0136 0.0701 0.0701
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0021 0.0007 0.0007
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0051 0.0063
Loa Loa (eye worm) hypothetical protein 0.0039 0.0115 0.0141
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0115 0.0606
Loa Loa (eye worm) hypothetical protein 0.0039 0.0115 0.0141
Trichomonas vaginalis histone deacetylase, putative 0.0464 0.2667 0.3266
Schistosoma mansoni tubulin subunit beta 0.1379 0.8166 0.8797
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.0021 0.0007 0.0008
Toxoplasma gondii ABC1 family protein 0.0039 0.0115 0.0133
Loa Loa (eye worm) CBP-B 0.0083 0.0382 0.0468
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0082
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0162 0.0858 0.105
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0131 0.0668 0.0818
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0051 0.0055
Schistosoma mansoni thyroid hormone receptor 0.0271 0.1512 0.1629
Onchocerca volvulus 0.0062 0.0255 0.0877
Schistosoma mansoni nuclear hormone receptor 0.0062 0.0255 0.0274
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0131 0.0668 0.0668
Trypanosoma cruzi beta tubulin, putative 0.1379 0.8166 1
Loa Loa (eye worm) hypothetical protein 0.031 0.1747 0.214
Loa Loa (eye worm) hypothetical protein 0.0051 0.019 0.0233
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0082 0.0377 0.0462
Loa Loa (eye worm) hypothetical protein 0.0037 0.0107 0.0131
Giardia lamblia Alpha-tubulin 0.1046 0.6167 0.7552
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0074 0.033 0.033
Trichomonas vaginalis bromodomain-containing protein, putative 0.0092 0.0434 0.0531
Leishmania major zeta tubulin, putative 0.0336 0.1904 0.2331
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0701 0.0859
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0131 0.0668 0.072
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0062 0.0255 0.0255
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0021 0.0007 0.0008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0136 0.0701 0.0701
Echinococcus multilocularis peroxisome assembly protein 26 0.1046 0.6167 0.6167
Leishmania major beta tubulin 0.1379 0.8166 1
Schistosoma mansoni brca1-associated protein (brap2) 0.0021 0.0007 0.0007
Plasmodium vivax histone deacetylase, putative 0.0255 0.1413 0.1723
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0336 0.1904 0.2325
Brugia malayi p25-alpha family protein 0.0392 0.224 0.2744
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Echinococcus multilocularis transfer RNA-Lys 0.0039 0.0115 0.0115
Schistosoma mansoni ap endonuclease 0.0039 0.0118 0.0127
Loa Loa (eye worm) pax transcription factor protein 2 0.0491 0.2834 0.3471
Toxoplasma gondii histone deacetylase HDAC5 0.0161 0.085 0.1034
Leishmania major histone deacetylase, putative 0.0255 0.1413 0.173
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.0584 0.0715
Leishmania major beta tubulin 0.1379 0.8166 1
Toxoplasma gondii histone deacetylase HDAC2 0.0464 0.2667 0.3261
Plasmodium vivax glutathione reductase, putative 0.0051 0.0188 0.0222
Echinococcus granulosus FTZ F1 alpha 0.0136 0.0701 0.0755
Trichomonas vaginalis tubulin alpha chain, putative 0.0775 0.4536 0.5555
Echinococcus granulosus histone acetyltransferase KAT2B 0.0297 0.1665 0.1793
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0051 0.0063
Trichomonas vaginalis tubulin beta chain, putative 0.1046 0.6167 0.7552
Treponema pallidum exodeoxyribonuclease (exoA) 0.0039 0.0118 0.0248
Echinococcus multilocularis histone deacetylase 0.0255 0.1413 0.1413
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Plasmodium falciparum alpha tubulin 1 0.1046 0.6167 0.755
Leishmania major beta tubulin 0.1379 0.8166 1
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0115 0.0575 0.0705
Trypanosoma brucei histone deacetylase 4 0.0255 0.1413 0.173
Echinococcus multilocularis Smad4 0.0067 0.0287 0.0287
Echinococcus granulosus tubulin alpha 1C chain 0.1046 0.6167 0.6644
Brugia malayi Isocitrate dehydrogenase 0.0131 0.0668 0.0818
Entamoeba histolytica hypothetical protein 0.0297 0.1669 0.2044
Onchocerca volvulus 0.0045 0.0153 0.0518
Brugia malayi phosphofructokinase 0.0117 0.0584 0.0715
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0115 0.0141
Trypanosoma brucei zeta tubulin, putative 0.0336 0.1904 0.2331
Giardia lamblia Epsilon tubulin 0.0336 0.1904 0.2331
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0021 0.0007 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0007 0.0008
Onchocerca volvulus 0.0039 0.0115 0.0384
Echinococcus multilocularis Tubulin beta 2C chain 0.1379 0.8166 0.8166
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0062 0.0255 0.0274
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0051 0.0063
Loa Loa (eye worm) hypothetical protein 0.0175 0.0935 0.1145
Trichomonas vaginalis histone deacetylase, putative 0.0464 0.2667 0.3266
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0039 0.0118 0.0137
Leishmania major beta tubulin 0.1379 0.8166 1
Trypanosoma brucei beta tubulin 0.1379 0.8166 1
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0021 0.0007 0.0008
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0021 0.0007 0.0008
Trichomonas vaginalis tubulin beta chain, putative 0.1046 0.6167 0.7552
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.008 0.008
Schistosoma mansoni histone deacetylase 0.0464 0.2667 0.2873
Trichomonas vaginalis histone deacetylase, putative 0.0464 0.2667 0.3266
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0073 0.0089
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0131 0.0668 0.0668
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.0584 0.279
Mycobacterium leprae Probable lipase LipE 0.0039 0.0115 0.054
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0115 0.0576 0.3023
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0062 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0701 0.0859
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0046 0.0046
Echinococcus multilocularis beta tubulin 0.1379 0.8166 0.8166
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0013 0.007
Brugia malayi nuclear hormone receptor 0.0136 0.0701 0.0859
Loa Loa (eye worm) DR-78 0.0062 0.0255 0.0312
Onchocerca volvulus 0.0033 0.0081 0.0262
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.0007 0.0008
Onchocerca volvulus 0.0031 0.0068 0.0218
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0136 0.0701 0.0859
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0007 0.0008
Brugia malayi Tubulin beta chain 0.0438 0.2516 0.3081
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0051 0.0051
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0332 0.0407
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0242 0.1336 0.1439
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.008 0.0086
Brugia malayi Pre-SET motif family protein 0.0033 0.008 0.0098
Trypanosoma brucei histone deacetylase 2 0.0161 0.085 0.1041
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0154 0.0189
Echinococcus granulosus histone acetyltransferase KAT2B 0.0092 0.0434 0.0467
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0051 0.0063
Brugia malayi Tubulin alpha-2 chain 0.1046 0.6167 0.7552
Schistosoma mansoni thyroid hormone receptor 0.0271 0.1512 0.1629
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0115 0.0124
Trypanosoma brucei alpha tubulin 0.1046 0.6167 0.7552
Echinococcus multilocularis mothers against decapentaplegic 5 0.0067 0.0287 0.0287
Schistosoma mansoni smad 0.003 0.0064 0.0069
Echinococcus multilocularis tubulin alpha 0.0775 0.4536 0.4536
Loa Loa (eye worm) hypothetical protein 0.0039 0.0115 0.0141
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0135 0.0165
Trypanosoma brucei beta tubulin 0.0775 0.4536 0.5555
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0283 0.0305
Loa Loa (eye worm) tubulin beta-4 chain 0.1379 0.8166 1
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0115 0.0606
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0115 0.0606
Echinococcus granulosus chromobox protein 1 0.0075 0.0332 0.0358
Trypanosoma cruzi histone deacetylase, putative 0.0255 0.1413 0.173
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0336 0.1904 0.2325
Loa Loa (eye worm) isocitrate dehydrogenase 0.0131 0.0668 0.0818
Echinococcus multilocularis tubulin gamma 1 chain 0.0775 0.4536 0.4536
Brugia malayi Smad1 0.0067 0.0287 0.0352
Trypanosoma brucei alpha tubulin 0.1046 0.6167 0.7552
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0062 0.0255 0.0877
Schistosoma mansoni tubulin subunit beta 0.1379 0.8166 0.8797
Trichomonas vaginalis histone deacetylase, putative 0.0464 0.2667 0.3266
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0073 0.0089
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0459 0.0495
Echinococcus multilocularis thymidylate synthase 0.0115 0.0576 0.0576
Loa Loa (eye worm) histone deacetylase 7A 0.0255 0.1413 0.173
Brugia malayi photoreceptor-specific nuclear receptor 0.0136 0.0701 0.0859
Leishmania major beta tubulin 0.1379 0.8166 1
Loa Loa (eye worm) tubulin alpha 2 0.071 0.4147 0.5078
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.0021 0.0007 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0115 0.0141
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0491 0.0601
Schistosoma mansoni histone deacetylase 4 5 0.0255 0.1413 0.1522
Echinococcus granulosus tubulin alpha 3 chain 0.1046 0.6167 0.6644
Toxoplasma gondii beta tubulin 0.1379 0.8166 1
Brugia malayi Pre-SET motif family protein 0.0224 0.1228 0.1504
Brugia malayi jmjC domain containing protein 0.0059 0.0238 0.0292
Brugia malayi nuclear receptor RXR 0.0062 0.0255 0.0312
Loa Loa (eye worm) hypothetical protein 0.0055 0.0214 0.0262
Loa Loa (eye worm) MH2 domain-containing protein 0.0067 0.0287 0.0352
Echinococcus multilocularis muscleblind protein 1 0.031 0.1747 0.1747
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.0255 0.0274
Echinococcus multilocularis jun protein 0.009 0.0424 0.0424
Brugia malayi Tubulin beta chain 0.0336 0.1904 0.2331
Loa Loa (eye worm) hypothetical protein 0.0074 0.033 0.0404
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.0007 0.0008
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0491 0.0601
Mycobacterium ulcerans thymidylate synthase 0.0115 0.0576 0.3023
Trypanosoma cruzi zeta tubulin, putative 0.0336 0.1904 0.2331
Mycobacterium ulcerans endonuclease IV 0.0082 0.0377 0.1981
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Loa Loa (eye worm) hypothetical protein 0.0033 0.0081 0.0099
Trichomonas vaginalis tubulin beta-1 chain, putative 0.0336 0.1904 0.2331
Echinococcus multilocularis tubulin subunit beta 0.1379 0.8166 0.8166
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0013 0.007
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0115 0.0133
Echinococcus multilocularis tubulin alpha 3 chain 0.1046 0.6167 0.6167
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0076 0.0093
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0082 0.0377 0.1981
Trypanosoma cruzi PAB1-binding protein , putative 0.0127 0.0648 0.0794
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.0584 0.0629
Giardia lamblia Beta tubulin 0.1379 0.8166 1
Schistosoma mansoni hypothetical protein 0.0073 0.0323 0.0348
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Loa Loa (eye worm) hypothetical protein 0.071 0.4147 0.5078
Leishmania major beta tubulin 0.1379 0.8166 1
Brugia malayi histone deacetylase 1 (HD1) 0.0464 0.2667 0.3266
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0115 0.0115
Brugia malayi histone deacetylase 11 0.0161 0.085 0.1041
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0459 0.0495
Loa Loa (eye worm) acetyltransferase 0.0307 0.1727 0.2115
Brugia malayi hypothetical protein 0.0074 0.033 0.0404
Plasmodium vivax tubulin alpha chain, putative 0.1046 0.6167 0.755
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0136 0.0701 0.0755
Echinococcus granulosus peroxisome assembly protein 26 0.1046 0.6167 0.6644
Brugia malayi BRCA1-associated protein 2 containing protein 0.0021 0.0007 0.0008
Onchocerca volvulus Mothers against decapentaplegic homolog 0.003 0.0064 0.0203
Trypanosoma cruzi histone deacetylase, putative 0.0161 0.085 0.1041
Leishmania major histone deacetylase, putative 0.0464 0.2667 0.3266
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.1365 0.717
Schistosoma mansoni transcription factor LCR-F1 0.0297 0.1669 0.1798
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0082 0.0377 0.0454
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0153 0.0165
Onchocerca volvulus 0.0039 0.0115 0.0384
Echinococcus granulosus BRCA1 associated protein 0.0021 0.0007 0.0007
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.008 0.0086
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Plasmodium falciparum histone deacetylase 2 0.0255 0.1413 0.1723
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0115 0.0141
Schistosoma mansoni brca1-associated protein (brap2) 0.0021 0.0007 0.0007
Echinococcus multilocularis cpg binding protein 0.0033 0.0079 0.0079
Entamoeba histolytica hypothetical protein 0.0297 0.1669 0.2044
Schistosoma mansoni smad1 5 8 and 0.0067 0.0287 0.031
Brugia malayi nuclear receptor NHR-88 0.0062 0.0255 0.0312
Plasmodium vivax delta tubulin, putative 0.0336 0.1904 0.2325
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0115 0.0141
Trypanosoma cruzi histone deacetylase 1, putative 0.0464 0.2667 0.3266
Echinococcus multilocularis tubulin alpha 1C chain 0.1046 0.6167 0.6167
Brugia malayi exodeoxyribonuclease III family protein 0.0039 0.0118 0.0145
Echinococcus granulosus Tubulin alpha 1 chain 0.1046 0.6167 0.6644
Echinococcus multilocularis dihydrofolate reductase 0.0047 0.0166 0.0166
Loa Loa (eye worm) dihydrofolate reductase 0.0047 0.0166 0.0203
Loa Loa (eye worm) hypothetical protein 0.0039 0.0115 0.0141
Echinococcus granulosus histone deacetylase 1 0.0464 0.2667 0.2873
Schistosoma mansoni chromobox protein 0.0075 0.0332 0.0358
Plasmodium vivax histone deacetylase 1, putative 0.0464 0.2667 0.3261
Leishmania major beta tubulin 0.1379 0.8166 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0073 0.0081
Schistosoma mansoni tubulin subunit alpha 0.1046 0.6167 0.6644
Onchocerca volvulus 0.0136 0.0701 0.2456
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0115 0.0576 0.2974
Echinococcus multilocularis tubulin delta chain 0.0336 0.1904 0.1904
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0039 0.0118 0.0145
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0249 0.0268
Echinococcus granulosus chromobox protein 1 0.0075 0.0332 0.0358
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Schistosoma mansoni histone deacetylase hda2 0.0275 0.1536 0.1655
Echinococcus multilocularis CREB binding protein 0.0082 0.0376 0.0376
Giardia lamblia Histone acetyltransferase GCN5 0.0082 0.0377 0.0462
Echinococcus multilocularis musashi 0.0056 0.022 0.022
Echinococcus granulosus tubulin alpha 0.0775 0.4536 0.4887
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Schistosoma mansoni cpg binding protein 0.0031 0.0068 0.0074
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0064 0.0078
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.009 0.0424 0.0457
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.0584 0.0715
Echinococcus granulosus thymidylate synthase 0.0115 0.0576 0.062
Echinococcus granulosus histone deacetylase 8 0.0161 0.085 0.0916
Trypanosoma cruzi histone deacetylase 1, putative 0.0464 0.2667 0.3266
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0115 0.0124
Loa Loa (eye worm) tubulin alpha chain 0.1046 0.6167 0.7552
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0076 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.008 0.0086
Loa Loa (eye worm) hypothetical protein 0.0074 0.033 0.0404
Schistosoma mansoni zinc finger protein 0.0062 0.0255 0.0274
Schistosoma mansoni nuclear receptor 0.0062 0.0255 0.0274
Mycobacterium ulcerans hypothetical protein 0.0039 0.0115 0.0606
Echinococcus granulosus CREB binding protein 0.0075 0.0331 0.0357
Plasmodium vivax tubulin gamma chain, putative 0.0775 0.4536 0.5551
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0188 0.0188
Trypanosoma brucei histone deacetylase 3 0.0255 0.1413 0.173
Echinococcus granulosus mothers against decapentaplegic 2 0.003 0.0064 0.0069
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.0007 0.0008
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0584 0.0715
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0131 0.0668 0.3509
Toxoplasma gondii beta-1 tubulin, putative 0.1379 0.8166 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0459 0.0495
Plasmodium vivax ataxin-2 like protein, putative 0.0127 0.0648 0.0786
Onchocerca volvulus 0.0115 0.0576 0.2012
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0052 0.0276
Loa Loa (eye worm) hypothetical protein 0.0136 0.0701 0.0859
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0129 0.0656 0.3445
Brugia malayi MH1 domain containing protein 0.0037 0.0107 0.0131
Echinococcus granulosus tubulin beta 1 chain 0.1379 0.8166 0.8797
Echinococcus granulosus ecdysone induced protein 78C 0.0136 0.0701 0.0755
Toxoplasma gondii beta-tubulin, putative 0.1379 0.8166 1
Brugia malayi beta-tubulin, identical 0.1379 0.8166 1
Echinococcus multilocularis GPCR, family 2 0.0032 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Trichomonas vaginalis tubulin, putative 0.0438 0.2516 0.3081
Loa Loa (eye worm) intermediate filament protein 0.0056 0.022 0.0269
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Toxoplasma gondii LsmAD domain-containing protein 0.0127 0.0648 0.0786
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0136 0.0701 0.0859
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.0007 0.0008
Brugia malayi Cytochrome P450 family protein 0.0079 0.0357 0.0437
Schistosoma mansoni retinoic acid receptor RXR 0.0242 0.1336 0.1439
Echinococcus granulosus lamin dm0 0.0056 0.022 0.0237
Loa Loa (eye worm) tubulin beta-1 chain 0.1379 0.8166 1
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Schistosoma mansoni hypothetical protein 0.0032 0.0076 0.0082
Loa Loa (eye worm) nuclear factor I 0.0037 0.0107 0.0131
Echinococcus granulosus histone deacetylase 7 0.0255 0.1413 0.1522
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0082 0.0377 0.1925
Loa Loa (eye worm) MH2 domain-containing protein 0.0987 0.5811 0.7116
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0116 0.0578 0.3037
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0116 0.0578 0.3037
Plasmodium falciparum flap endonuclease 1 0.0028 0.0051 0.0055
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Echinococcus multilocularis histone deacetylase 6 0.0255 0.1413 0.1413
Trichomonas vaginalis tubulin epsilon chain, putative 0.0336 0.1904 0.2331
Schistosoma mansoni hypothetical protein 0.0069 0.0299 0.0322
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0116 0.0579 0.0709
Loa Loa (eye worm) hypothetical protein 0.0032 0.0076 0.0093
Leishmania major beta tubulin 0.1379 0.8166 1
Brugia malayi intermediate filament protein 0.0056 0.022 0.0269
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0136 0.0701 0.0859
Leishmania major cytochrome p450-like protein 0.0028 0.0052 0.0064
Leishmania major beta tubulin 0.1379 0.8166 1
Brugia malayi Nuclear hormone receptor E75 0.0062 0.0255 0.0312
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0131 0.0668 0.072
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0249 0.0268
Trypanosoma cruzi zeta tubulin, putative 0.0336 0.1904 0.2331
Echinococcus granulosus Nuclear hormone receptor HR96 0.0062 0.0255 0.0274
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0074 0.033 0.0356
Loa Loa (eye worm) hypoxia-induced factor 1 0.0161 0.0853 0.1045
Mycobacterium tuberculosis Probable dehydrogenase 0.0116 0.0578 0.3037
Schistosoma mansoni hypothetical protein 0.1565 0.9283 1
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0332 0.0407
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.0584 0.0715
Echinococcus multilocularis BRCA1 associated protein 0.0021 0.0007 0.0007
Echinococcus multilocularis Tubulin alpha 1 chain 0.1046 0.6167 0.6167
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.0584 0.3066
Trichomonas vaginalis set domain proteins, putative 0.0255 0.1413 0.1731
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0136 0.0701 0.0755
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.0127 0.0648 0.0794
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0188 0.0222
Trichomonas vaginalis tubulin alpha chain, putative 0.0438 0.2516 0.3081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0136 0.0701 0.0859
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0115 0.0141
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0162 0.0858 0.105
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Leishmania major beta tubulin 0.1379 0.8166 1
Trichomonas vaginalis tubulin, putative 0.0438 0.2516 0.3081
Echinococcus multilocularis tubulin beta 1 chain 0.1379 0.8166 0.8166
Trichomonas vaginalis tubulin alpha chain, putative 0.0438 0.2516 0.3081
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0115 0.0606
Onchocerca volvulus Histone deacetylase 10 homolog 0.0161 0.085 0.2984
Brugia malayi MH2 domain containing protein 0.0987 0.5811 0.7116
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0062 0.0255 0.0255
Schistosoma mansoni nuclear receptor nhr-48 0.0062 0.0255 0.0274
Toxoplasma gondii isocitrate dehydrogenase 0.0131 0.0668 0.081
Echinococcus granulosus tubulin epsilon chain 0.0775 0.4536 0.4887
Onchocerca volvulus Protein ultraspiracle homolog 0.0136 0.0701 0.2456
Echinococcus multilocularis isocitrate dehydrogenase 0.0131 0.0668 0.0668
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0238 0.0238
Leishmania major epsilon tubulin, putative 0.0775 0.4536 0.5555
Brugia malayi 6-phosphofructokinase 0.0117 0.0584 0.0715
Schistosoma mansoni lamin 0.0056 0.022 0.0237
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0076 0.0082
Brugia malayi MH1 domain containing protein 0.0067 0.0287 0.0352
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Brugia malayi hypothetical protein 0.0055 0.0213 0.0261
Mycobacterium ulcerans cell division protein FtsZ 0.0336 0.1904 1
Trypanosoma brucei alpha tubulin 0.1046 0.6167 0.7552
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0068 0.0084
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.0042 0.0135 0.0165
Loa Loa (eye worm) tubulin alpha 2 0.0272 0.1514 0.1855
Toxoplasma gondii thioredoxin reductase 0.0051 0.0188 0.0222
Trichomonas vaginalis tubulin beta chain, putative 0.1046 0.6167 0.7552
Echinococcus granulosus tubulin alpha chain 0.1046 0.6167 0.6644
Plasmodium falciparum tubulin delta chain, putative 0.0336 0.1904 0.2325
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0136 0.0701 0.0859
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0074 0.033 0.0356
Schistosoma mansoni Smad4 0.003 0.0064 0.0069
Schistosoma mansoni hypothetical protein 0.0135 0.0694 0.0748
Entamoeba histolytica hypothetical protein 0.0297 0.1669 0.2044
Schistosoma mansoni cpg binding protein 0.0033 0.0079 0.0085
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0136 0.0701 0.0755
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0297 0.1669 0.1798
Chlamydia trachomatis endonuclease IV 0.0082 0.0377 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.071 0.4147 0.5078
Schistosoma mansoni single-minded 0.0052 0.0197 0.0212
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0052 0.0064
Leishmania major alpha tubulin 0.1046 0.6167 0.7552
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0115 0.0141
Schistosoma mansoni histone deacetylase 0.0464 0.2667 0.2873
Brugia malayi steroid hormone receptor 0.0136 0.0701 0.0859
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0057 0.0227 0.0227
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0136 0.0701 0.0701
Echinococcus granulosus dihydrofolate reductase 0.0047 0.0166 0.0179
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0069 0.0074
Trypanosoma brucei histone deacetylase 1 0.0464 0.2667 0.3266
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0073 0.0089
Loa Loa (eye worm) cytochrome P450 family protein 0.0079 0.0357 0.0437
Brugia malayi Nuclear hormone receptor-like 1 0.0074 0.033 0.0404
Loa Loa (eye worm) BEN-1 protein 0.1379 0.8166 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0775 0.4536 0.5551
Brugia malayi ecdysteroid receptor 0.0136 0.0701 0.0859
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0046 0.0049
Echinococcus multilocularis mothers against decapentaplegic 6 0.003 0.0064 0.0064
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0062 0.0255 0.0255
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0135 0.0694 0.0748
Echinococcus granulosus tubulin alpha chain 0.1046 0.6167 0.6644
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0162 0.0858 0.1043
Brugia malayi Tubulin gamma chain 0.0775 0.4536 0.5555
Schistosoma mansoni jumonji domain containing protein 0.0059 0.0238 0.0257
Echinococcus multilocularis Tubulin beta 2C chain 0.1379 0.8166 0.8166
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0073 0.0089
Plasmodium vivax tubulin epsilon chain, putative 0.0775 0.4536 0.5551
Trichomonas vaginalis tubulin gamma chain, putative 0.0775 0.4536 0.5555
Loa Loa (eye worm) transcription factor SMAD2 0.0987 0.5811 0.7116
Treponema pallidum cell division protein FtsZ 0.0336 0.1904 1
Brugia malayi Tubulin alpha-2 chain 0.1046 0.6167 0.7552
Echinococcus granulosus jun protein 0.009 0.0424 0.0457
Schistosoma mansoni nuclear receptor 0.0062 0.0255 0.0274
Entamoeba histolytica tubulin alpha-1 chain 0.1046 0.6167 0.7552
Echinococcus granulosus mothers against decapentaplegic 6 0.003 0.0064 0.0069
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0307 0.1727 0.1727
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0188 0.023
Loa Loa (eye worm) beta-tubulin 0.1379 0.8166 1
Echinococcus granulosus histone deacetylase 6 0.0255 0.1413 0.1522
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0007 0.0008
Brugia malayi Histone deacetylase 1 0.0464 0.2667 0.3266
Schistosoma mansoni alpha tubulin 0.1046 0.6167 0.6644
Trichomonas vaginalis tubulin alpha chain, putative 0.1379 0.8166 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.1046 0.6167 0.6167
Trichomonas vaginalis tubulin, putative 0.1379 0.8166 1
Trypanosoma brucei histone deacetylase, putative 0.0255 0.1413 0.173
Schistosoma mansoni tubulin subunit beta 0.0336 0.1904 0.2051
Onchocerca volvulus 0.0255 0.1413 0.4974
Schistosoma mansoni tubulin subunit alpha 0.1046 0.6167 0.6644
Loa Loa (eye worm) hypothetical protein 0.0115 0.0575 0.0705
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0062 0.0255 0.0274
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0039 0.0118 0.0145
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.0584 0.0715
Loa Loa (eye worm) nuclear hormone receptor 0.0062 0.0255 0.0312
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0007 0.0008
Loa Loa (eye worm) glutathione reductase 0.0051 0.0188 0.023
Plasmodium vivax tubulin beta chain, putative 0.1379 0.8166 1
Loa Loa (eye worm) tubulin beta chain 0.0336 0.1904 0.2331
Mycobacterium ulcerans epimerase 0.0022 0.0013 0.007
Onchocerca volvulus 0.0438 0.2516 0.8874
Schistosoma mansoni RAR-like nuclear receptor 0.0136 0.0701 0.0755
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0039 0.0118 0.0621
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0056 0.022 0.0269
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0307 0.1727 0.1861
Brugia malayi 6-phosphofructokinase 0.0117 0.0584 0.0715
Trypanosoma brucei epsilon tubulin 0.0775 0.4536 0.5555
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0039 0.0118 0.0145
Loa Loa (eye worm) steroid hormone receptor 0.0136 0.0701 0.0859
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0188 0.023
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0052 0.0064
Entamoeba histolytica hypothetical protein 0.0297 0.1669 0.2044
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.0007 0.0008
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.0584 0.3066
Trichomonas vaginalis brca1-associated protein, putative 0.0021 0.0007 0.0008
Schistosoma mansoni tubulin subunit gamma 0.0775 0.4536 0.4887
Schistosoma mansoni steroid hormone receptor ad4bp 0.0136 0.0701 0.0755
Echinococcus multilocularis histone deacetylase 8 0.0161 0.085 0.085
Plasmodium falciparum thioredoxin reductase 0.0051 0.0188 0.0222
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0459 0.0459
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0135 0.0454
Trypanosoma brucei alpha tubulin, putative 0.0438 0.2516 0.3081
Brugia malayi hypothetical protein 0.0071 0.0308 0.0377
Echinococcus granulosus Tubulin beta 2C chain 0.1379 0.8166 0.8797
Brugia malayi nuclear hormone receptor family member odr-7 0.0062 0.0255 0.0312
Trichomonas vaginalis BRCA1-associated protein, putative 0.0021 0.0007 0.0008
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0135 0.0694 0.0694
Plasmodium vivax tubulin alpha chain, putative 0.1046 0.6167 0.755
Entamoeba histolytica tubulin alpha chain, putative 0.1046 0.6167 0.7552
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0701 0.0859
Loa Loa (eye worm) hypothetical protein 0.0039 0.0115 0.0141
Plasmodium falciparum ataxin-2 like protein, putative 0.0127 0.0648 0.0786
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0115 0.0141
Loa Loa (eye worm) histone deacetylase 3 0.0464 0.2667 0.3266
Echinococcus multilocularis lamin 0.0056 0.022 0.022
Echinococcus granulosus cpg binding protein 0.0033 0.0079 0.0085
Brugia malayi beta-lactamase family protein 0.0039 0.0115 0.0141
Schistosoma mansoni tubulin subunit delta 0.0336 0.1904 0.2051
Brugia malayi Tubulin alpha chain 0.1046 0.6167 0.7552
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0459 0.0495
Brugia malayi ecdysone receptor 0.0062 0.0255 0.0312
Loa Loa (eye worm) phosphofructokinase 0.0117 0.0584 0.0715
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0115 0.0576 0.062
Echinococcus multilocularis lamin dm0 0.0056 0.022 0.022
Trypanosoma brucei epsilon tubulin 0.0775 0.4536 0.5555
Echinococcus granulosus Tubulin beta 2C chain 0.1379 0.8166 0.8797
Loa Loa (eye worm) hypothetical protein 0.0062 0.0255 0.0312
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.0007 0.0008
Schistosoma mansoni jun-related protein 0.0073 0.0323 0.0348
Echinococcus multilocularis ecdysone induced protein 78C 0.0136 0.0701 0.0701
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0701 0.0755
Schistosoma mansoni nuclear hormone receptor 0.0136 0.0701 0.0755
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0131 0.0668 0.081
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0332 0.0407

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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