Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0205 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0269 | 0.1269 | 0.2113 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0054 | 0.0054 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 0.0087 | 0.0771 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0581 | 0.289 | 0.289 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0078 | 0.0078 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 0.0439 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0042 | 0.0087 | 0.0145 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0029 | 0.0019 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0264 | 0.0264 |
Entamoeba histolytica | hypothetical protein | 0.0029 | 0.0019 | 0.0152 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0615 | 0.3067 | 0.5108 |
Onchocerca volvulus | 0.0029 | 0.0019 | 0.0053 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0269 | 0.1269 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0041 | 0.0078 | 0.0613 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0615 | 0.3067 | 0.3067 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0133 | 0.0557 | 0.0928 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0046 | 0.0107 | 0.0107 |
Echinococcus granulosus | intermediate filament protein | 0.0046 | 0.0107 | 0.0178 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0729 | 0.3662 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0042 | 0.0087 | 0.0145 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.003 | 0.0024 | 0.0212 |
Onchocerca volvulus | 0.0041 | 0.0078 | 0.0212 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0336 | 0.056 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 0.5261 |
Echinococcus granulosus | Smad4 | 0.0133 | 0.0557 | 0.0928 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 0.2309 |
Onchocerca volvulus | 0.0046 | 0.0107 | 0.0292 | |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0243 | 0.1131 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0042 | 0.0087 | 0.0145 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0019 | 0.017 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.003 | 0.0024 | 0.0184 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0036 | 0.0054 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.0615 | 0.3067 | 0.4523 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.0029 | 0.0019 | 0.0325 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0029 | 0.0019 | 0.0029 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0131 | 0.055 | 0.0915 |
Onchocerca volvulus | 0.0457 | 0.2243 | 0.6125 | |
Brugia malayi | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0029 | 0.0019 | 0.0182 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.005 | 0.0127 | 0.2375 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0036 | 0.0054 | 0.0054 |
Brugia malayi | AMP-binding enzyme family protein | 0.0041 | 0.0078 | 0.0078 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0059 | 0.0175 | 0.0292 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0133 | 0.0557 | 0.0557 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 0.8911 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.055 | 0.055 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 0.055 | 0.055 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 0.0087 | 0.0771 |
Brugia malayi | Probable ClpP-like protease | 0.0076 | 0.0264 | 0.0264 |
Schistosoma mansoni | Smad4 | 0.0059 | 0.0175 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Onchocerca volvulus | Huntingtin homolog | 0.0108 | 0.0427 | 0.1166 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0041 | 0.0078 | 0.1322 |
Brugia malayi | MH2 domain containing protein | 0.0133 | 0.0557 | 0.0557 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 0.0087 | 0.0771 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0229 | 0.1056 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0059 | 0.0175 | 0.0292 |
Brugia malayi | jmjC domain containing protein | 0.0079 | 0.028 | 0.028 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.005 | 0.0127 | 0.2569 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.1056 | 0.1056 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.1947 | 1 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 0.2472 |
Loa Loa (eye worm) | hypothetical protein | 0.0457 | 0.2243 | 0.2243 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0041 | 0.0078 | 0.1258 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0581 | 0.289 | 0.289 |
Loa Loa (eye worm) | nuclear factor I | 0.0073 | 0.0249 | 0.0249 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0019 | 0.017 |
Brugia malayi | TAR-binding protein | 0.0581 | 0.289 | 0.289 |
Brugia malayi | MH2 domain containing protein | 0.0133 | 0.0557 | 0.0557 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0427 | 0.0427 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0029 | 0.0019 | 0.0032 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0029 | 0.0019 | 0.0019 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0042 | 0.0087 | 0.0087 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0046 | 0.0107 | 0.0107 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0041 | 0.0078 | 0.1542 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0029 | 0.0019 | 0.0028 |
Loa Loa (eye worm) | Smad1 | 0.0133 | 0.0557 | 0.0557 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0019 | 0.017 |
Schistosoma mansoni | hypothetical protein | 0.0269 | 0.1269 | 0.1871 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0024 | 0.0024 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.005 | 0.0127 | 0.2375 |
Schistosoma mansoni | lamin | 0.0046 | 0.0107 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0175 | 0.0175 |
Echinococcus granulosus | peptidase Clp S14 family | 0.005 | 0.0127 | 0.0212 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0042 | 0.0087 | 0.0611 |
Schistosoma mansoni | hypothetical protein | 0.0103 | 0.04 | 0.059 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0065 | 0.0205 | 0.4038 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 0.0439 |
Brugia malayi | MH1 domain containing protein | 0.0073 | 0.0249 | 0.0249 |
Echinococcus multilocularis | Smad4 | 0.0133 | 0.0557 | 0.0928 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0065 | 0.0205 | 0.0341 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0042 | 0.0087 | 0.0096 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0036 | 0.0054 | 0.0089 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0041 | 0.0078 | 0.1542 |
Echinococcus granulosus | lamin dm0 | 0.0046 | 0.0107 | 0.0178 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.1912 |
Entamoeba histolytica | hypothetical protein | 0.0269 | 0.1269 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0615 | 0.3067 | 0.3067 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Brugia malayi | hypothetical protein | 0.0148 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0059 | 0.0175 | 0.0175 |
Leishmania major | hypothetical protein, conserved | 0.0229 | 0.1056 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0059 | 0.0175 | 0.0175 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0041 | 0.0078 | 0.1258 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0341 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0059 | 0.0175 | 0.0292 |
Echinococcus granulosus | GPCR family 2 | 0.0615 | 0.3067 | 0.5108 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0042 | 0.0087 | 0.0825 |
Brugia malayi | MH1 domain containing protein | 0.0073 | 0.0249 | 0.0249 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0041 | 0.0078 | 0.1322 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0103 | 0.04 | 0.0667 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.0336 | 0.0336 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0341 |
Loa Loa (eye worm) | TAR-binding protein | 0.0581 | 0.289 | 0.289 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Schistosoma mansoni | dep domain containing protein | 0.0036 | 0.0054 | 0.0079 |
Schistosoma mansoni | dishevelled | 0.0036 | 0.0054 | 0.0079 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0036 | 0.0054 | 0.0089 |
Echinococcus granulosus | tar DNA binding protein | 0.0581 | 0.289 | 0.4813 |
Brugia malayi | DIX domain containing protein | 0.0036 | 0.0054 | 0.0054 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0269 | 0.1269 | 0.2113 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Entamoeba histolytica | hypothetical protein | 0.0269 | 0.1269 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0065 | 0.0205 | 0.194 |
Echinococcus multilocularis | nibrin | 0.0029 | 0.0019 | 0.0032 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0029 | 0.0019 | 0.0019 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0065 | 0.0205 | 0.1791 |
Brugia malayi | intermediate filament protein | 0.0046 | 0.0107 | 0.0107 |
Trypanosoma brucei | protein kinase, putative | 0.0042 | 0.0087 | 0.0655 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.0029 | 0.0019 | 0.0148 |
Loa Loa (eye worm) | intermediate filament protein | 0.0046 | 0.0107 | 0.0107 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.005 | 0.0127 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0083 | 0.0083 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0019 | 0.017 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0615 | 0.3067 | 0.5108 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0054 | 0.0054 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0054 | 0.0054 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0205 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0108 | 0.0427 | 0.1166 |
Onchocerca volvulus | 0.0036 | 0.0054 | 0.0146 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.0336 | 0.056 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0336 | 0.0496 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0036 | 0.0054 | 0.0054 |
Echinococcus granulosus | lamin | 0.0046 | 0.0107 | 0.0178 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.1912 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0059 | 0.0175 | 0.0292 |
Schistosoma mansoni | regulator of G protein signaling | 0.0036 | 0.0054 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0024 | 0.0024 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0229 | 0.1056 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0041 | 0.0078 | 0.0613 |
Brugia malayi | MAP kinase sur-1 | 0.0042 | 0.0087 | 0.0087 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0041 | 0.0078 | 0.1258 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 0.8911 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0029 | 0.0019 | 0.0019 |
Schistosoma mansoni | smad | 0.0133 | 0.0557 | 0.0822 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0036 | 0.0054 | 0.0054 |
Toxoplasma gondii | hypothetical protein | 0.0036 | 0.0054 | 0.0475 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0336 | 0.0496 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0119 | 0.0484 | 1 |
Schistosoma mansoni | lamin | 0.0046 | 0.0107 | 0.0157 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.1944 | 0.9982 | 0.9982 |
Loa Loa (eye worm) | hypothetical protein | 0.1944 | 0.9982 | 0.9982 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0042 | 0.0087 | 0.0655 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0024 | 0.0024 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0029 | 0.0019 | 0.0032 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Brugia malayi | RNA binding protein | 0.0581 | 0.289 | 0.289 |
Echinococcus multilocularis | lamin dm0 | 0.0046 | 0.0107 | 0.0178 |
Treponema pallidum | DNA ligase (lig) | 0.0029 | 0.0019 | 0.0139 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0065 | 0.0205 | 0.1912 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.0336 | 0.0496 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0029 | 0.0019 | 0.0182 |
Loa Loa (eye worm) | RNA binding protein | 0.0581 | 0.289 | 0.289 |
Schistosoma mansoni | topbp1 | 0.0029 | 0.0019 | 0.0028 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.0336 | 0.0336 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0036 | 0.0054 | 0.0089 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0341 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0076 | 0.0264 | 0.5261 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0029 | 0.0019 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Schistosoma mansoni | Smad4 | 0.0133 | 0.0557 | 0.0822 |
Schistosoma mansoni | smad | 0.0059 | 0.0175 | 0.0259 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0029 | 0.0019 | 0.0029 |
Brugia malayi | hypothetical protein | 0.0229 | 0.1056 | 0.1056 |
Echinococcus multilocularis | smad | 0.0133 | 0.0557 | 0.0928 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0054 | 0.0054 |
Schistosoma mansoni | tar DNA-binding protein | 0.0581 | 0.289 | 0.4262 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0133 | 0.0557 | 0.0557 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0034 | 0.0042 | 0.007 |
Echinococcus granulosus | muscleblind protein | 0.0131 | 0.055 | 0.0915 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0059 | 0.0175 | 0.0479 |
Brugia malayi | topoisomerase | 0.0029 | 0.0019 | 0.0019 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0059 | 0.0175 | 0.0175 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.005 | 0.0127 | 0.0127 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.1947 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0457 | 0.2243 | 0.2243 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0042 | 0.0087 | 0.0825 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0079 | 0.028 | 0.0466 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0341 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0029 | 0.0019 | 0.0152 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0133 | 0.0557 | 0.0928 |
Brugia malayi | Muscleblind-like protein | 0.0131 | 0.055 | 0.055 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.003 | 0.0024 | 0.0111 |
Schistosoma mansoni | dishevelled | 0.0036 | 0.0054 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0427 | 0.0427 |
Brugia malayi | MH1 domain containing protein | 0.0133 | 0.0557 | 0.0557 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0133 | 0.0557 | 0.0557 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0041 | 0.0078 | 0.1258 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.0029 | 0.0019 | 0.0148 |
Schistosoma mansoni | hypothetical protein | 0.0615 | 0.3067 | 0.4523 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0036 | 0.0054 | 0.0089 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0065 | 0.0205 | 0.13 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0036 | 0.0054 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0615 | 0.3067 | 0.3067 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0133 | 0.0557 | 0.0822 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0036 | 0.0054 | 0.0079 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0036 | 0.0054 | 0.0079 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0264 | 0.2472 |
Schistosoma mansoni | jumonji domain containing protein | 0.0063 | 0.0195 | 0.0287 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0119 | 0.0484 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0076 | 0.0264 | 0.5415 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0041 | 0.0078 | 0.1258 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0029 | 0.0019 | 0.017 |
Brugia malayi | Smad1 | 0.0133 | 0.0557 | 0.0557 |
Echinococcus granulosus | jumonji domain containing protein | 0.0034 | 0.0042 | 0.007 |
Entamoeba histolytica | hypothetical protein | 0.0269 | 0.1269 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0042 | 0.0087 | 0.0771 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0041 | 0.0078 | 0.1258 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0076 | 0.0264 | 0.2472 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0042 | 0.0087 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0024 | 0.0024 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0036 | 0.0054 | 0.0089 |
Echinococcus multilocularis | tar DNA binding protein | 0.0581 | 0.289 | 0.4813 |
Schistosoma mansoni | intermediate filament proteins | 0.0046 | 0.0107 | 0.0157 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0065 | 0.0205 | 0.1912 |
Echinococcus granulosus | nibrin | 0.0029 | 0.0019 | 0.0032 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0079 | 0.028 | 0.0466 |
Loa Loa (eye worm) | hypothetical protein | 0.1329 | 0.6782 | 0.6782 |
Brugia malayi | Isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0205 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0036 | 0.0054 | 0.0054 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0229 | 0.1056 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0581 | 0.289 | 0.4262 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0302 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0065 | 0.0205 | 0.1791 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0078 | 0.1258 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 0.0087 | 0.0129 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0042 | 0.0087 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0729 | 0.3662 | 0.3662 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0029 | 0.0019 | 0.0182 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0042 | 0.0087 | 0.0794 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.003 | 0.0024 | 0.0198 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0029 | 0.0019 | 0.0032 |
Echinococcus multilocularis | GPCR, family 2 | 0.0615 | 0.3067 | 0.5108 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0103 | 0.04 | 0.0667 |
Brugia malayi | hypothetical protein | 0.0269 | 0.1269 | 0.1269 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0041 | 0.0078 | 0.0613 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0133 | 0.0557 | 0.0928 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0229 | 0.1056 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.003 | 0.0024 | 0.0198 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0243 | 0.1131 | 1 |
Onchocerca volvulus | 0.0046 | 0.0107 | 0.0292 | |
Schistosoma mansoni | DNA ligase IV | 0.0029 | 0.0019 | 0.0028 |
Schistosoma mansoni | topbp1 | 0.0029 | 0.0019 | 0.0028 |
Brugia malayi | AMP-binding enzyme family protein | 0.0041 | 0.0078 | 0.0078 |
Schistosoma mansoni | tar DNA-binding protein | 0.0581 | 0.289 | 0.4262 |
Brugia malayi | DKFZp564C0469 protein | 0.0029 | 0.0019 | 0.0019 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0243 | 0.1131 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0336 | 0.056 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0712 | 0.3574 | 0.5951 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0029 | 0.0019 | 0.0032 |
Echinococcus granulosus | microtubule associated protein 2 | 0.118 | 0.6006 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0729 | 0.3662 | 0.3662 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0024 | 0.0024 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.118 | 0.6006 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.1944 | 0.9982 | 0.9982 |
Schistosoma mansoni | smad1 5 8 and | 0.0133 | 0.0557 | 0.0822 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0615 | 0.3067 | 0.3067 |
Echinococcus granulosus | smad | 0.0133 | 0.0557 | 0.0928 |
Brugia malayi | AMP-binding enzyme family protein | 0.0041 | 0.0078 | 0.0078 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.1944 | 0.9982 | 0.9982 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0019 | 0.0019 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.0336 | 0.056 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0029 | 0.0019 | 0.0148 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0269 | 0.1269 | 0.1871 |
Schistosoma mansoni | tar DNA-binding protein | 0.0581 | 0.289 | 0.4262 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0029 | 0.0019 | 0.017 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0042 | 0.0087 | 0.0825 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0042 | 0.0087 | 0.0096 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0229 | 0.1056 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0615 | 0.3067 | 0.4523 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0065 | 0.0205 | 0.194 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0615 | 0.3067 | 0.5108 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0076 | 0.0264 | 0.2472 |
Schistosoma mansoni | smad1 5 8 and | 0.0133 | 0.0557 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0107 | 0.0107 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0119 | 0.0484 | 1 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0054 | 0.0054 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0065 | 0.0205 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0078 | 0.0078 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0041 | 0.0078 | 0.1258 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0036 | 0.0054 | 0.0089 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0615 | 0.3067 | 0.5108 |
Schistosoma mansoni | tar DNA-binding protein | 0.0581 | 0.289 | 0.4262 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0029 | 0.0019 | 0.0182 |
Brugia malayi | jmjC domain containing protein | 0.0029 | 0.0019 | 0.0019 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0036 | 0.0054 | 0.0089 |
Schistosoma mansoni | smad1 5 8 and | 0.0133 | 0.0557 | 0.0822 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0133 | 0.0557 | 0.0928 |
Echinococcus multilocularis | muscleblind protein | 0.0131 | 0.055 | 0.0915 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0229 | 0.1056 | 1 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0036 | 0.0054 | 0.0054 |
Schistosoma mansoni | microtubule-associated protein tau | 0.118 | 0.6006 | 0.8856 |
Schistosoma mansoni | Smad4 | 0.0059 | 0.0175 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0249 | 0.0249 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0029 | 0.0019 | 0.017 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0036 | 0.0054 | 0.0146 |
Brugia malayi | hypothetical protein | 0.0108 | 0.0427 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0078 | 0.0078 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0229 | 0.1056 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0059 | 0.0175 | 0.0175 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0076 | 0.0264 | 0.0389 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0029 | 0.0019 | 0.017 |
Schistosoma mansoni | hypothetical protein | 0.0615 | 0.3067 | 0.4523 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0036 | 0.0054 | 0.0089 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.1329 | 0.6782 | 0.6782 |
Schistosoma mansoni | hypothetical protein | 0.1329 | 0.6782 | 1 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0029 | 0.0019 | 0.017 |
Echinococcus multilocularis | musashi | 0.0046 | 0.0107 | 0.0178 |
Echinococcus multilocularis | lamin | 0.0046 | 0.0107 | 0.0178 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 402 uM | Compound was tested for its ability to inhibit the thrombin-induced platelet aggregation in washed human platelets | ChEMBL. | 9873606 |
IC50 (functional) | = 402 uM | Compound was tested for its ability to inhibit the thrombin-induced platelet aggregation in washed human platelets | ChEMBL. | 9873606 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.