Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0219 | 0.0733 |
Mycobacterium tuberculosis | Probable amidase AmiB2 (aminohydrolase) | 0.025 | 0.116 | 0.2764 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.025 | 0.116 | 0.3205 |
Leishmania major | protein kinase, putative | 0.0019 | 0.0039 | 0.0109 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0092 | 0.0092 |
Entamoeba histolytica | protein kinase, putative | 0.0284 | 0.1323 | 0.8876 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0035 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0012 | 0.0008 | 0.0008 |
Brugia malayi | hypothetical protein | 0.004 | 0.014 | 0.014 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.2075 | 1 | 1 |
Schistosoma mansoni | amidase | 0.2075 | 1 | 1 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0058 | 0.0227 | 0.0311 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0058 | 0.0227 | 0.0761 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0047 | 0.0047 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0019 | 0.0039 | 0.0109 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0341 | 0.1602 | 0.553 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0047 | 0.0047 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.0125 | 0.0406 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0056 | 0.0219 | 0.0048 |
Echinococcus granulosus | single minded 2 | 0.0035 | 0.0119 | 0.0119 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | loxhd1 | 0.004 | 0.014 | 0.014 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0341 | 0.1602 | 0.553 |
Mycobacterium ulcerans | amidase | 0.025 | 0.116 | 0.2989 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0121 | 0.0121 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0154 | 0.0693 | 0.1906 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0093 | 0.04 | 0.04 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0607 | 0.2891 | 0.2891 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0092 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0056 | 0.0219 | 0.0733 |
Mycobacterium tuberculosis | Probable amidase AmiD (acylamidase) (acylase) | 0.025 | 0.116 | 0.2764 |
Mycobacterium tuberculosis | Probable amidase AmiC (aminohydrolase) | 0.025 | 0.116 | 0.2764 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0084 | 0.0084 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0037 | 0.0125 | 0.0125 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0056 | 0.0219 | 0.0733 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0056 | 0.0219 | 0.0219 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0047 | 0.0047 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0056 | 0.0219 | 0.0733 |
Brugia malayi | Cytochrome P450 family protein | 0.0058 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0047 | 0.0047 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0219 | 0.0733 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0058 | 0.0227 | 0.0311 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0084 | 0.0084 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0058 | 0.0227 | 0.0311 |
Schistosoma mansoni | hypothetical protein | 0.0401 | 0.1891 | 0.1891 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0047 | 0.0047 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0401 | 0.1891 | 0.1891 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | CMGC/CLK protein kinase | 0.0607 | 0.2891 | 0.2891 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0047 | 0.0242 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | amidase | 0.025 | 0.116 | 0.116 |
Leishmania major | hypothetical protein, conserved | 0.025 | 0.116 | 0.3998 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0111 | 0.0487 | 0.0487 |
Brugia malayi | Doublecortin family protein | 0.004 | 0.014 | 0.014 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.014 | 0.014 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0607 | 0.2891 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0341 | 0.1602 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0093 | 0.04 | 0.04 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0058 | 0.0227 | 0.0311 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0744 | 0.3551 | 0.3551 |
Loa Loa (eye worm) | cytochrome P450 | 0.0058 | 0.0227 | 0.0227 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.036 | 0.1691 | 0.5839 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0289 | 0.1346 | 0.4414 |
Brugia malayi | Protein kinase domain containing protein | 0.0607 | 0.2891 | 0.2891 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0058 | 0.0227 | 0.0311 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0019 | 0.0039 | 0.0109 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.004 | 0.014 | 0.014 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0093 | 0.04 | 0.1361 |
Brugia malayi | hypothetical protein | 0.004 | 0.014 | 0.014 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0093 | 0.04 | 0.04 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0093 | 0.04 | 0.0807 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0284 | 0.1323 | 0.456 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.025 | 0.116 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.052 | 0.2469 | 0.8537 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0058 | 0.0227 | 0.0311 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0058 | 0.0227 | 0.0311 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.014 | 0.014 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0037 | 0.0125 | 0.0125 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0058 | 0.0227 | 0.0078 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0058 | 0.0227 | 0.0311 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0056 | 0.0219 | 0.0219 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0058 | 0.0227 | 0.037 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0047 | 0.0242 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0019 | 0.0039 | 0.0109 |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.02 | 0.02 |
Mycobacterium ulcerans | peptide amidase, GatA | 0.025 | 0.116 | 0.2989 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0058 | 0.0227 | 0.0227 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0056 | 0.0219 | 0.0341 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0047 | 0.0047 |
Plasmodium vivax | serine/threonine kinase-1, putative | 0.0607 | 0.2891 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.025 | 0.116 | 0.116 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0284 | 0.1323 | 0.456 |
Echinococcus granulosus | dnaJ subfamily B | 0.0401 | 0.1891 | 0.1891 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1291 | 0.1291 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0056 | 0.0219 | 0.0341 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0037 | 0.0125 | 0.0406 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0058 | 0.0227 | 0.0761 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0341 | 0.1602 | 0.553 |
Trypanosoma brucei | kinetoplastid kinetochore protein 19 | 0.0607 | 0.2891 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0111 | 0.0487 | 0.0487 |
Mycobacterium tuberculosis | Probable amidase AmiA2 (aminohydrolase) | 0.025 | 0.116 | 0.2764 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.052 | 0.2469 | 0.8537 |
Onchocerca volvulus | 0.004 | 0.014 | 0.0831 | |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.2075 | 1 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0058 | 0.0227 | 0.0311 |
Brugia malayi | Amidase family protein | 0.025 | 0.116 | 0.116 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.025 | 0.116 | 0.116 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.02 | 0.02 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0135 | 0.0604 | 0.0604 |
Entamoeba histolytica | hypothetical protein | 0.0284 | 0.1323 | 0.8876 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.0179 | 0.0179 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0047 | 0.0047 |
Trypanosoma cruzi | amidase, putative | 0.025 | 0.116 | 0.3998 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.014 | 0.014 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0058 | 0.0227 | 0.0311 |
Onchocerca volvulus | 0.0028 | 0.0084 | 0.0479 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0219 | 0.0733 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0058 | 0.0227 | 0.0311 |
Leishmania major | protein kinase, putative | 0.0019 | 0.0039 | 0.0109 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0341 | 0.1602 | 0.553 |
Mycobacterium ulcerans | amidase | 0.025 | 0.116 | 0.2989 |
Loa Loa (eye worm) | hypothetical protein | 0.0277 | 0.1291 | 0.1291 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0058 | 0.0227 | 0.0311 |
Loa Loa (eye worm) | doublecortin family protein | 0.004 | 0.014 | 0.014 |
Echinococcus multilocularis | dual specificity protein kinase clk2 | 0.0607 | 0.2891 | 0.2891 |
Brugia malayi | Amidase family protein | 0.025 | 0.116 | 0.116 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0125 | 0.0125 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0047 | 0.0047 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.02 | 0.02 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0255 | 0.1183 | 0.1183 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.052 | 0.2469 | 0.2469 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0047 | 0.0047 |
Echinococcus granulosus | dual specificity | 0.0284 | 0.1323 | 0.1323 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0607 | 0.2891 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0056 | 0.0219 | 0.0219 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.004 | 0.014 | 0.014 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0487 | 0.231 | 0.231 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0047 | 0.0047 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0341 | 0.1602 | 0.553 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0341 | 0.1602 | 0.553 |
Echinococcus multilocularis | glutamyl tRNA(Gln) amidotransferase subunit A | 0.025 | 0.116 | 0.116 |
Mycobacterium tuberculosis | Possible amidase (aminohydrolase) | 0.025 | 0.116 | 0.2764 |
Echinococcus multilocularis | 0.0058 | 0.0227 | 0.0227 | |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.025 | 0.116 | 0.3709 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0284 | 0.1323 | 0.1323 |
Onchocerca volvulus | 0.004 | 0.014 | 0.0831 | |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0047 | 0.0047 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0056 | 0.0219 | 0.0733 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0012 | 0.0008 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.0227 | 0.0227 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0755 | 0.3604 | 1 |
Leishmania major | protein kinase, putative | 0.0607 | 0.2891 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0135 | 0.0604 | 0.0604 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.014 | 0.014 |
Echinococcus granulosus | RUN | 0.004 | 0.014 | 0.014 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.052 | 0.2469 | 0.8537 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.0125 | 0.0406 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0058 | 0.0227 | 0.0761 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 19, putative | 0.0607 | 0.2891 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0047 | 0.0047 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0111 | 0.0487 | 0.0487 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0047 | 0.0047 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0047 | 0.0047 |
Onchocerca volvulus | 0.0052 | 0.02 | 0.1203 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0058 | 0.0227 | 0.061 |
Trypanosoma cruzi | amidase, putative | 0.025 | 0.116 | 0.3998 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0744 | 0.3551 | 0.3551 |
Loa Loa (eye worm) | amidase | 0.025 | 0.116 | 0.116 |
Schistosoma mansoni | lipoxygenase | 0.004 | 0.014 | 0.014 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0047 | 0.0047 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0056 | 0.0219 | 0.0733 |
Leishmania major | cytochrome p450-like protein | 0.0058 | 0.0227 | 0.0761 |
Brugia malayi | dihydrofolate reductase family protein | 0.0755 | 0.3604 | 0.3604 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0037 | 0.0125 | 0.0125 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.2075 | 1 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0289 | 0.1346 | 0.4641 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.0125 | 0.0125 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0284 | 0.1323 | 0.8876 |
Mycobacterium leprae | putative cytochrome p450 | 0.0058 | 0.0227 | 0.061 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0093 | 0.04 | 0.04 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.0125 | 0.0406 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0755 | 0.3604 | 1 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.0125 | 0.0125 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0315 | 0.1474 | 0.4878 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.1183 | 0.1183 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0019 | 0.0039 | 0.0109 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.014 | 0.014 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0092 | 0.0092 |
Giardia lamblia | Kinase, CMGC CLK | 0.0607 | 0.2891 | 1 |
Trypanosoma brucei | kinetoplastid kinetochore protein 10 | 0.0607 | 0.2891 | 1 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0037 | 0.0125 | 0.0125 |
Trypanosoma cruzi | kinetoplastid kinetochore protein 10, putative | 0.0607 | 0.2891 | 1 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0058 | 0.0227 | 0.0311 |
Brugia malayi | hypothetical protein | 0.016 | 0.0723 | 0.0723 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0607 | 0.2891 | 0.2891 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.0179 | 0.0179 |
Leishmania major | cytochrome p450-like protein | 0.0093 | 0.04 | 0.1361 |
Echinococcus granulosus | glutamyl tRNAGln amidotransferase subunit A | 0.025 | 0.116 | 0.116 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0037 | 0.0125 | 0.0125 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0056 | 0.0219 | 0.0733 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0289 | 0.1346 | 0.4244 |
Echinococcus granulosus | hypothetical protein | 0.0601 | 0.2859 | 0.2859 |
Schistosoma mansoni | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.025 | 0.116 | 0.116 |
Brugia malayi | follicle stimulating hormone receptor | 0.0487 | 0.231 | 0.231 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0047 | 0.0047 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.2075 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.014 | 0.014 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0047 | 0.0047 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | Dihydrofolate reductase | 0.0755 | 0.3604 | 0.3604 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0047 | 0.0047 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0755 | 0.3604 | 1 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0755 | 0.3604 | 1 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.025 | 0.116 | 0.3205 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 1 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0284 | 0.1323 | 0.433 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.014 | 0.014 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.2075 | 1 | 1 |
Echinococcus granulosus | dual specificity protein kinase clk2 | 0.0607 | 0.2891 | 0.2891 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0284 | 0.1323 | 0.456 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0755 | 0.3604 | 0.3604 |
Entamoeba histolytica | protein kinase, putative | 0.0284 | 0.1323 | 0.8876 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.052 | 0.2469 | 0.2469 |
Schistosoma mansoni | polycystin 1-related | 0.004 | 0.014 | 0.014 |
Mycobacterium ulcerans | amidase | 0.025 | 0.116 | 0.2989 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0607 | 0.2891 | 1 |
Echinococcus multilocularis | 0.0601 | 0.2859 | 0.2859 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.014 | 0.014 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0047 | 0.0047 |
Trypanosoma brucei | protein kinase, putative | 0.0056 | 0.0219 | 0.0341 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0047 | 0.0047 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0341 | 0.1602 | 0.553 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | dihydrofolate reductase | 0.0755 | 0.3604 | 0.3604 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.0125 | 0.0125 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0056 | 0.0219 | 0.0219 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0056 | 0.0219 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0601 | 0.2859 | 0.2859 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0237 | 0.0237 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0058 | 0.0227 | 0.0311 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0056 | 0.0219 | 0.0219 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0047 | 0.0047 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0058 | 0.0227 | 0.0311 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0093 | 0.04 | 0.1361 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0047 | 0.0047 |
Leishmania major | protein kinase, putative | 0.0607 | 0.2891 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0056 | 0.0219 | 0.0219 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.036 | 0.1691 | 0.5839 |
Onchocerca volvulus | 0.002 | 0.0047 | 0.0242 | |
Brugia malayi | cytochrome P450 | 0.0058 | 0.0227 | 0.0227 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.025 | 0.116 | 0.3205 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0755 | 0.3604 | 0.3604 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.014 | 0.014 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0047 | 0.0047 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0154 | 0.0693 | 0.1381 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0154 | 0.0693 | 0.1649 |
Mycobacterium ulcerans | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.025 | 0.116 | 0.2989 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0058 | 0.0227 | 0.0761 |
Echinococcus multilocularis | RUN | 0.004 | 0.014 | 0.014 |
Brugia malayi | hypoxia-induced factor 1 | 0.0148 | 0.0663 | 0.0663 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0047 | 0.0047 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.052 | 0.2469 | 0.8537 |
Schistosoma mansoni | single-minded | 0.0048 | 0.0179 | 0.0179 |
Echinococcus multilocularis | dual specificity | 0.0284 | 0.1323 | 0.1323 |
Echinococcus granulosus | dihydrofolate reductase | 0.0755 | 0.3604 | 0.3604 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0058 | 0.0227 | 0.0311 |
Brugia malayi | bHLH-PAS transcription factor | 0.0035 | 0.0119 | 0.0119 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0744 | 0.3551 | 0.3551 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0084 | 0.0084 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.0125 | 0.0406 |
Onchocerca volvulus | 0.0035 | 0.0119 | 0.0696 | |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0012 | 0.0008 | 0.0008 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0289 | 0.1346 | 0.4383 |
Brugia malayi | Cytochrome P450 family protein | 0.0093 | 0.04 | 0.04 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0047 | 0.0242 |
Mycobacterium ulcerans | amidase | 0.025 | 0.116 | 0.2989 |
Brugia malayi | Protein kinase domain containing protein | 0.0284 | 0.1323 | 0.1323 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0284 | 0.1323 | 0.1323 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | amidase | 0.025 | 0.116 | 0.2989 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0255 | 0.1183 | 0.1183 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.025 | 0.116 | 0.116 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0012 | 0.0008 | 0.0008 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0047 | 0.0047 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0289 | 0.1346 | 0.4383 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0315 | 0.1474 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.052 | 0.2469 | 0.8537 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0056 | 0.0219 | 0.0219 |
Brugia malayi | putative amidase | 0.025 | 0.116 | 0.116 |
Loa Loa (eye worm) | hypothetical protein | 0.2075 | 1 | 1 |
Schistosoma mansoni | cytochrome P450 | 0.0058 | 0.0227 | 0.0227 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0058 | 0.0227 | 0.0311 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0058 | 0.0227 | 0.0311 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0047 | 0.0047 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0315 | 0.1474 | 0.5086 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0289 | 0.1346 | 0.4641 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0047 | 0.0047 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0058 | 0.0227 | 0.0311 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.052 | 0.2469 | 0.8537 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0092 | 0.0092 |
Brugia malayi | hypothetical protein | 0.0255 | 0.1183 | 0.1183 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0012 | 0.0008 | 0.0008 |
Trypanosoma brucei | fatty-acid amide hydrolase, putative | 0.025 | 0.116 | 0.3744 |
Plasmodium falciparum | protein serine/threonine kinase-1 | 0.0607 | 0.2891 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.0723 | 0.0723 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0047 | 0.0047 |
Trypanosoma brucei | cytochrome P450, putative | 0.0093 | 0.04 | 0.0995 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0125 | 0.0406 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0058 | 0.0227 | 0.0311 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0047 | 0.0047 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0148 | 0.0663 | 0.0663 |
Toxoplasma gondii | cell-cycle-associated protein kinase CLK, putative | 0.0607 | 0.2891 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0047 | 0.0047 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0047 | 0.0047 |
Leishmania major | cytochrome p450-like protein | 0.0058 | 0.0227 | 0.0761 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.025 | 0.116 | 0.3709 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.