Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0078 | 0.2616 | 0.984 |
Brugia malayi | Pre-SET motif family protein | 0.0223 | 0.8702 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2616 | 0.5 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.069 | 0.2596 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2616 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.069 | 0.2638 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.069 | 0.2638 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0078 | 0.2616 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2616 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.069 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.069 | 0.0793 |
Brugia malayi | hypothetical protein | 0.0078 | 0.2616 | 0.2403 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0079 | 0.2658 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.069 | 0.2596 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0079 | 0.2658 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.069 | 0.5 |
Trichomonas vaginalis | set domain proteins, putative | 0.0253 | 0.9995 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2616 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.069 | 0.2638 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.2616 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0078 | 0.2616 | 0.984 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0641 | 0.241 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0223 | 0.8702 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.069 | 0.2638 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.069 | 0.2596 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.