TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 438.562 | Formula: C25H34N4O3
H donors: 4 H acceptors: 3 LogP: 3.19 Rotable bonds: 13
Rule of 5 violations (Lipinski): 1
SMILES: CN[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NC(c1ccccc1)c1ccccc1)C)C(C)C)C
InChi: 1S/C25H34N4O3/c1-16(2)21(28-23(30)17(3)26-5)25(32)27-18(4)24(31)29-22(19-12-8-6-9-13-19)20-14-10-7-11-15-20/h6-18,21-22,26H,1-5H3,(H,27,32)(H,28,30)(H,29,31)/t17-,18-,21-/m0/s1
InChiKey: XEZCUQUBJIJZQY-WFXMLNOXSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	TK/FER protein kinase	0.0033	0.4023	0.4023
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Mycobacterium tuberculosis	Probable cytochrome P450 125 Cyp125	0.0017	0	0.5
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/ALK protein kinase	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0043	0.6636	0.7164
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0033	0.4023	0.4023
Mycobacterium tuberculosis	Probable cytochrome P450 136 Cyp136	0.0017	0	0.5
Echinococcus multilocularis	FL cytokine receptor	0.0033	0.4023	0.4344
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0033	0.4023	0.4023
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0033	0.4023	0.5587
Echinococcus multilocularis	activated cdc42 kinase 1	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Schistosoma mansoni	kinase	0.0045	0.7201	1
Brugia malayi	Cytochrome P450 family protein	0.0026	0.2296	0.2296
Brugia malayi	SH2 domain containing protein	0.0043	0.6636	0.6636
Echinococcus granulosus	epidermal growth factor receptor	0.0033	0.4023	0.4344
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0043	0.6636	0.7164
Loa Loa (eye worm)	CMGC/CDK/CDK9 protein kinase	0.0045	0.7201	0.7201
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0043	0.6636	0.8221
Echinococcus multilocularis	insulin receptor	0.0033	0.4023	0.4344
Toxoplasma gondii	STE kinase	0.0033	0.4023	0.9804
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Onchocerca volvulus		0.0043	0.6636	1
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus granulosus	raf serine:threonine protein kinase	0.0033	0.4023	0.4344
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Loa Loa (eye worm)	TK/FER protein kinase	0.0033	0.4023	0.4023
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Echinococcus granulosus	activated cdc42 kinase 1	0.0033	0.4023	0.4344
Echinococcus multilocularis	tyrosine protein kinase csk	0.0033	0.4023	0.4344
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0033	0.4023	0.4344
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0033	0.4023	0.4344
Echinococcus granulosus	tyrosine kinase	0.0043	0.6636	0.7164
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0033	0.4023	0.4023
Mycobacterium tuberculosis	Probable cytochrome P450 144 Cyp144	0.0017	0	0.5
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0043	0.6636	0.7164
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0033	0.4023	0.5
Brugia malayi	Receptor family ligand binding region containing protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0043	0.6636	0.7164
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0033	0.4023	0.5587
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus granulosus	protein kinase	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	protein kinase atn1, putative	0.0033	0.4023	0.5
Giardia lamblia	Kinase, NEK	0.0033	0.4023	0.5
Leishmania major	hypothetical protein, conserved	0.0033	0.4023	0.9804
Loa Loa (eye worm)	TK/EPH protein kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	cyclin dependent kinase 9	0.0045	0.7201	0.7774
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Brugia malayi	hypothetical protein	0.0043	0.6636	0.6636
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0033	0.4023	0.4023
Brugia malayi	protein-tyrosine kinase	0.0043	0.6636	0.6636
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Onchocerca volvulus		0.0043	0.6636	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0033	0.4023	0.4023
Echinococcus granulosus	tyrosine protein kinase csk	0.0033	0.4023	0.4344
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0033	0.4023	0.5
Toxoplasma gondii	protein kinase domain-containing protein	0.0033	0.4023	0.9804
Echinococcus multilocularis	tyrosine protein kinase	0.0033	0.4023	0.4344
Loa Loa (eye worm)	cytochrome P450 family protein	0.0026	0.2296	0.2296
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK protein kinase	0.0043	0.6636	0.6636
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0033	0.4023	0.9804
Loa Loa (eye worm)	TK/RYK protein kinase	0.0033	0.4023	0.4023
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.0033	0.4023	0.4344
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Trichomonas vaginalis	STE family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Schistosoma mansoni	serine/threonine RGC	0.0033	0.4023	0.5587
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0033	0.4023	0.4344
Echinococcus multilocularis	tyrosine protein kinase csk	0.0033	0.4023	0.4344
Mycobacterium tuberculosis	Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM)	0.0017	0	0.5
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0043	0.6636	0.7164
Brugia malayi	integrin-linked kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0033	0.4023	0.4344
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Furin-like cysteine rich region family protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Mycobacterium tuberculosis	Cytochrome P450 121 Cyp121	0.0017	0	0.5
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0033	0.4104	0.4431
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trypanosoma cruzi	cytochrome P450, putative	0.0026	0.2296	0.5594
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Mycobacterium tuberculosis	Probable cytochrome P450 monooxygenase 142 Cyp142	0.0017	0	0.5
Trypanosoma brucei	cytochrome P450, putative	0.0026	0.2296	0.5594
Schistosoma mansoni	hypothetical protein	0.0033	0.4023	0.5587
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0033	0.4023	0.4344
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0043	0.6636	0.7164
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Echinococcus multilocularis	protein kinase	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Entamoeba histolytica	protein kinase domain containing protein	0.0045	0.7201	1
Onchocerca volvulus		0.0043	0.6636	1
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus granulosus	ephrin type A receptor 4 A	0.0033	0.4023	0.4344
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	transfer RNA-Thr	0.0033	0.4023	0.4344
Brugia malayi	Tyrosine-protein kinase abl-1	0.0043	0.6636	0.6636
Loa Loa (eye worm)	SRC-1	0.0043	0.6636	0.6636
Mycobacterium tuberculosis	Probable cytochrome P450 140 Cyp140	0.0017	0	0.5
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Echinococcus multilocularis	integrin linked protein kinase	0.0033	0.4023	0.4344
Onchocerca volvulus		0.0043	0.6636	1
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.0033	0.4023	0.4344
Mycobacterium tuberculosis	Probable cytochrome P450 141 Cyp141	0.0017	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0033	0.4023	0.5587
Mycobacterium tuberculosis	Probable cytochrome P450 138 Cyp138	0.0017	0	0.5
Echinococcus granulosus	cyclin dependent kinase 9	0.0052	0.9263	1
Echinococcus multilocularis	protein kinase	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Raf kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	tyrosine protein kinase csk	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0033	0.4023	0.4344
Echinococcus multilocularis	tyrosine protein kinase Blk	0.0043	0.6636	0.7164
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0033	0.4023	0.4344
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0033	0.4023	0.4344
Schistosoma mansoni	protein kinase	0.0033	0.4104	0.5699
Echinococcus multilocularis	heat shock protein 70	0.0033	0.4023	0.4344
Echinococcus multilocularis	tyrosine protein kinase csk	0.0033	0.4023	0.4344
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0043	0.6636	0.7164
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0043	0.6636	0.7164
Trichomonas vaginalis	TK family protein kinase	0.0033	0.4023	0.5
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0033	0.4023	0.4023
Echinococcus multilocularis	c src tyrosine kinase	0.0043	0.6636	0.7164
Echinococcus granulosus	activated cdc42 kinase 1	0.0033	0.4023	0.4344
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0033	0.4023	0.4023
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0033	0.4023	0.4023
Echinococcus granulosus	tyrosine kinase	0.0043	0.6636	0.7164
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	hypothetical protein	0.0043	0.6636	0.6636
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0033	0.4023	0.5587
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0043	0.6636	0.7164
Schistosoma mansoni	tyrosine protein kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus multilocularis	tyrosine kinase	0.0043	0.6636	0.7164
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Mycobacterium tuberculosis	Probable cytochrome P450 128 Cyp128	0.0017	0	0.5
Plasmodium vivax	tyrosine kinase-like protein, putative	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trypanosoma cruzi	protein kinase, putative	0.0033	0.4023	0.9804
Echinococcus multilocularis	protein tyrosine kinase	0.0033	0.4023	0.4344
Mycobacterium tuberculosis	Probable cytochrome P450 130 Cyp130	0.0017	0	0.5
Mycobacterium tuberculosis	Probable cytochrome P450 123 Cyp123	0.0017	0	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0043	0.6636	0.9215
Brugia malayi	ephrin receptor 1 precursor	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0033	0.4023	0.4023
Leishmania major	protein kinase, putative	0.0033	0.4104	1
Schistosoma mansoni	serine/threonine protein kinase	0.0033	0.4023	0.5587
Echinococcus multilocularis	activin receptor type	0.0033	0.4104	0.4431
Echinococcus granulosus	tyrosine protein kinase Blk	0.0043	0.6636	0.7164
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Echinococcus multilocularis	epidermal growth factor receptor	0.0033	0.4023	0.4344
Mycobacterium tuberculosis	Probable cytochrome P450 143 Cyp143	0.0017	0	0.5
Schistosoma mansoni	protein kinase	0.0033	0.4104	0.5699
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Toxoplasma gondii	Tyrosine kinase-like (TKL) protein	0.0033	0.4023	0.9804
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	cytochrome P450 family protein	0.0055	1	1
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0033	0.4023	0.4023
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0033	0.4023	0.4023
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Mycobacterium tuberculosis	Probable cytochrome P450 137 Cyp137	0.0017	0	0.5
Schistosoma mansoni	serine/threonine protein kinase	0.0033	0.4023	0.5587
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0033	0.4104	1
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Mycobacterium leprae	putative cytochrome p450	0.0017	0	0.5
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0033	0.4104	1
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Echinococcus granulosus	receptor type guanylyl cyclase	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Loa Loa (eye worm)	cytochrome P450 family protein	0.0026	0.2296	0.2296
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.4023	0.5
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0043	0.6636	0.7164
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	c src tyrosine kinase	0.0043	0.6636	0.7164
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0033	0.4023	0.4344
Brugia malayi	hypothetical protein	0.0033	0.4023	0.4023
Mycobacterium tuberculosis	Possible cytochrome P450 126 Cyp126	0.0017	0	0.5
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0043	0.6636	0.6636
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0033	0.4023	0.4023
Brugia malayi	Protein kinase domain containing protein	0.0043	0.6636	0.6636
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.0033	0.4023	0.4344
Trypanosoma brucei	Pseudokinase, putative	0.0033	0.4023	0.9804
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/INSR protein kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0033	0.4023	0.4344
Echinococcus multilocularis	tyrosine protein kinase shark	0.0043	0.6636	0.7164
Entamoeba histolytica	protein kinase domain containing protein	0.0033	0.4104	0.0253
Schistosoma mansoni	ephrin receptor	0.0033	0.4023	0.5587
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0043	0.6636	0.7164
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Echinococcus multilocularis	tyrosine protein kinase Srms	0.0043	0.6636	0.7164
Echinococcus multilocularis	cyclin dependent kinase 9	0.0052	0.9263	1
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Mycobacterium tuberculosis	Possible cytochrome P450 135B1 Cyp135B1	0.0017	0	0.5
Trypanosoma cruzi	cytochrome P450, putative	0.0026	0.2296	0.5594
Schistosoma mansoni	ephrin receptor	0.0033	0.4023	0.5587
Brugia malayi	hypothetical protein	0.0033	0.4023	0.4023
Brugia malayi	Protein kinase domain containing protein	0.0043	0.6636	0.6636
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Echinococcus granulosus	protein tyrosine kinase	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0033	0.4023	0.9804
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Mycobacterium tuberculosis	Probable cytochrome P450 132 Cyp132	0.0017	0	0.5
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0033	0.4023	0.4344
Brugia malayi	SH2 domain containing protein	0.0043	0.6636	0.6636
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0033	0.4023	0.4023
Brugia malayi	C-terminal src kinase protein 1	0.0033	0.4023	0.4023
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0033	0.4023	0.9804
Loa Loa (eye worm)	TK/CSK protein kinase	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	integrin linked protein kinase	0.0033	0.4023	0.4344
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0043	0.6636	0.7164
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0033	0.4023	0.4023
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0033	0.4023	0.4344
Schistosoma mansoni	serine/threonine protein kinase	0.0033	0.4023	0.5587
Loa Loa (eye worm)	CYP4Cod1	0.0026	0.2296	0.2296
Echinococcus granulosus	activin receptor type	0.0033	0.4104	0.4431
Echinococcus multilocularis	tyrosine kinase	0.0033	0.4023	0.4344
Plasmodium falciparum	protein kinase, putative	0.0033	0.4104	1
Schistosoma mansoni	protein tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0033	0.4023	0.4344
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0033	0.4023	0.4344
Schistosoma mansoni	serine/threonine protein kinase	0.0045	0.7201	1
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Mycobacterium leprae	Conserved hypothetical protein	0.0017	0	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0033	0.4023	0.4023
Schistosoma mansoni	protein kinase	0.0033	0.4104	0.5699
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0033	0.4023	0.5587
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Schistosoma mansoni	tyrosine kinase	0.0043	0.6636	0.9215
Echinococcus granulosus	cyclin dependent kinase 9	0.0045	0.7201	0.7774
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	tyrosine protein kinase csk	0.0033	0.4023	0.4344
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0043	0.6636	0.9215
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0043	0.6636	0.7164
Onchocerca volvulus		0.0043	0.6636	1
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK/FER protein kinase	0.0033	0.4023	0.4023
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0033	0.4023	0.4344
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Onchocerca volvulus		0.0043	0.6636	1
Mycobacterium tuberculosis	Probable cytochrome P450 139 Cyp139	0.0017	0	0.5
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0043	0.6716	0.7251
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0033	0.4104	0.4431
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0033	0.4104	1
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	tyrosine protein kinase	0.0033	0.4023	0.4344
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.4023	0.5
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Trichomonas vaginalis	CAMK family protein kinase	0.0033	0.4023	0.5
Giardia lamblia	Protein 21.1	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/DDR protein kinase	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0033	0.4023	0.4344
Echinococcus granulosus	natriuretic peptide receptor 1	0.0033	0.4023	0.4344
Echinococcus multilocularis	epidermal growth factor receptor	0.0033	0.4023	0.4344
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0033	0.4023	0.4344
Plasmodium vivax	protein kinase, putative	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK/FER protein kinase	0.0033	0.4023	0.4023
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0033	0.4104	1
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0033	0.4023	0.4344
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0033	0.4023	0.5
Loa Loa (eye worm)	TK/FER protein kinase	0.0043	0.6636	0.6636
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0043	0.6636	0.7164
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0033	0.4023	0.4344
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0033	0.4023	0.5587
Toxoplasma gondii	protein kinase	0.0033	0.4023	0.9804
Leishmania major	cytochrome p450-like protein	0.0026	0.2296	0.5594
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0043	0.6636	0.7164
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0033	0.4023	0.4344
Echinococcus granulosus	tyrosine protein kinase pr2	0.0033	0.4023	0.4344
Brugia malayi	Tyrosine-protein kinase PR2	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0033	0.4023	0.4023
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.4023	0.5
Echinococcus granulosus	tyrosine protein kinase shark	0.0043	0.6636	0.7164
Echinococcus granulosus	epidermal growth factor receptor	0.0033	0.4023	0.4344
Echinococcus granulosus	insulin receptor	0.0033	0.4023	0.4344
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Protein kinase domain containing protein	0.0043	0.6636	0.6636
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK protein kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0043	0.6636	0.9215
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Schistosoma mansoni	protein kinase	0.0033	0.4023	0.5587
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0033	0.4023	0.4023
Brugia malayi	Protein kinase domain containing protein	0.0043	0.6636	0.6636
Schistosoma mansoni	serine/threonine protein kinase	0.0033	0.4023	0.5587
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0033	0.4023	0.4023
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0043	0.6636	0.7164
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Mycobacterium tuberculosis	Probable cytochrome P450 124 Cyp124	0.0017	0	0.5
Loa Loa (eye worm)	TK/ACK protein kinase	0.0033	0.4023	0.4023
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0043	0.6636	0.9215
Brugia malayi	SRC-1	0.0043	0.6636	0.6636
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0033	0.4023	0.4344
Brugia malayi	cyclin-dependent kinase 9	0.0045	0.7201	0.7201
Loa Loa (eye worm)	TK/ABL protein kinase	0.0043	0.6636	0.6636
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.0026	0.2296	1
Loa Loa (eye worm)	TK/FAK protein kinase	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Echinococcus granulosus	tyrosine kinase	0.0033	0.4023	0.4344
Trypanosoma cruzi	protein kinase, putative	0.0033	0.4023	0.9804
Mycobacterium tuberculosis	Possible cytochrome P450 135A1 Cyp135A1	0.0017	0	0.5
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0033	0.4023	0.4023
Giardia lamblia	Kinase, NEK	0.0033	0.4023	0.5
Brugia malayi	Cytochrome P450 family protein	0.0026	0.2296	0.2296
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Schistosoma mansoni	tyrosine kinase	0.0043	0.6636	0.9215
Loa Loa (eye worm)	TK/Met protein kinase	0.0033	0.4023	0.4023
Giardia lamblia	Kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	serine/threonine protein kinase	0.0033	0.4023	0.4023
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0033	0.4023	0.4344
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	AGC family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Echinococcus granulosus	tyrosine protein kinase csk	0.0033	0.4023	0.4344
Brugia malayi	Guanylyl cyclase protein 23	0.0033	0.4023	0.4023
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Leishmania major	protein kinase, putative	0.0033	0.4023	0.9804
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0043	0.6636	0.7164
Echinococcus granulosus	tyrosine protein kinase HCK	0.0033	0.4023	0.4344
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0033	0.4023	0.4023
Trypanosoma brucei	protein kinase, putative	0.0033	0.4104	1
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0033	0.4023	0.5
Schistosoma mansoni	tyrosine kinase	0.0043	0.6636	0.9215
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0033	0.4023	0.4344
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0033	0.4023	0.4344
Loa Loa (eye worm)	TK/FER protein kinase	0.0033	0.4023	0.4023
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Loa Loa (eye worm)	hypothetical protein	0.0033	0.4023	0.4023
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0043	0.6636	0.7164
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Trichomonas vaginalis	TKL family protein kinase	0.0033	0.4023	0.5
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0033	0.4023	0.4023
Echinococcus granulosus	kinase suppressor of Ras 1	0.0033	0.4023	0.4344
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Schistosoma mansoni	tyrosine kinase	0.0033	0.4023	0.5587
Echinococcus granulosus	tyrosine protein kinase Srms	0.0043	0.6636	0.7164
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0033	0.4023	0.4344
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0033	0.4023	0.4344
Brugia malayi	Protein kinase domain containing protein	0.0033	0.4023	0.4023
Loa Loa (eye worm)	TK/ROR protein kinase	0.0033	0.4023	0.4023

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1616935

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1476109