TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 564.762 | Formula: C30H36N4O3S2
H donors: 0 H acceptors: 4 LogP: 5.86 Rotable bonds: 12
Rule of 5 violations (Lipinski): 2
SMILES: CCN(S(=O)(=O)c1ccc(cc1)C(=O)N(c1sc2c(n1)c(C)c(cc2)C)CCCN(C)C)Cc1ccccc1
InChi: 1S/C30H36N4O3S2/c1-6-33(21-24-11-8-7-9-12-24)39(36,37)26-16-14-25(15-17-26)29(35)34(20-10-19-32(4)5)30-31-28-23(3)22(2)13-18-27(28)38-30/h7-9,11-18H,6,10,19-21H2,1-5H3
InChiKey: NNWLPSHIRKXURN-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Mycobacterium leprae	PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5)	0.0038	0.0037	0.5
Onchocerca volvulus		0.0035	0.0015	0.0009
Brugia malayi	hypothetical protein	0.006	0.0184	0.0321
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Echinococcus granulosus	neuropeptide Y receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	neurotransmitter gated ion channel	0.0087	0.0365	0.0365
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0126	0.0631	0.1099
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0844	0.5451	0.5451
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0161	0.0864	0.1505
Onchocerca volvulus		0.0085	0.0351	0.092
Echinococcus granulosus	Dipeptidyl peptidase 9	0.0132	0.0668	0.0668
Onchocerca volvulus		0.0118	0.0574	0.1524
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0228	0.1311	0.2283
Toxoplasma gondii	histone lysine methyltransferase SET8	0.0066	0.0224	0.0777
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.1521	1	1
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	hypothetical protein	0.006	0.0184	0.0321
Echinococcus granulosus	dipeptidyl aminopeptidaseprotein	0.0392	0.2416	0.2416
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0161	0.0864	0.0864
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Echinococcus granulosus	somatostatin receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	integrin alpha-ps	0.0039	0.0044	0.0044
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Echinococcus granulosus	beta-adrenergic receptor kinase	0.0098	0.0439	0.0439
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Onchocerca volvulus		0.0085	0.0351	0.092
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0583	0.3699	0.3699
Trichomonas vaginalis	proprotein convertase subtilisin/kexin type, putative	0.0172	0.0935	0.2746
Trypanosoma brucei	DNA polymerase IV, putative	0.0036	0.0023	0.0346
Schistosoma mansoni	neuropeptide f receptor 76f	0.0085	0.0351	0.0351
Plasmodium falciparum	plasmepsin III	0.0118	0.0574	0.1988
Onchocerca volvulus		0.0042	0.0062	0.0135
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0038	0.0037	0.0037
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	histamine h1 receptor	0.0085	0.0351	0.0351
Brugia malayi	celfurPC protein	0.0716	0.459	0.7992
Trichomonas vaginalis	Clan AA, family A1, cathepsin D-like aspartic peptidase	0.0462	0.2887	0.8479
Onchocerca volvulus		0.0118	0.0574	0.1524
Echinococcus multilocularis	somatostatin receptor	0.0085	0.0351	0.0351
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0034	0.0012	0.0035
Onchocerca volvulus		0.0035	0.0015	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Trypanosoma cruzi	aminopeptidase, putative	0.0034	0.0012	0.018
Brugia malayi	hypothetical protein	0.0074	0.0281	0.049
Onchocerca volvulus		0.0085	0.0351	0.092
Brugia malayi	pregnancy-associated plasma protein-A	0.006	0.0184	0.0321
Onchocerca volvulus		0.0085	0.0351	0.092
Trypanosoma cruzi	serine peptidase, clan SB, family S8-like protein	0.0038	0.0037	0.0552
Trichomonas vaginalis	cyclin B, putative	0.0042	0.0062	0.0181
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Onchocerca volvulus		0.0116	0.0563	0.1495
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Echinococcus granulosus	g protein coupled receptor	0.0085	0.0351	0.0351
Plasmodium falciparum	subtilisin-like protease 3	0.0038	0.0037	0.0128
Brugia malayi	RE15519p	0.0085	0.0351	0.0612
Mycobacterium leprae	Possible secreted protease	0.0038	0.0037	0.5
Brugia malayi	neuropeptide F receptor	0.0085	0.0351	0.0612
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Echinococcus granulosus	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Brugia malayi	hypothetical protein	0.006	0.0184	0.0321
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0085	0.0351	0.0351
Loa Loa (eye worm)	acetylcholine receptor protein	0.0074	0.0281	0.049
Loa Loa (eye worm)	hypothetical protein	0.014	0.072	0.1253
Plasmodium vivax	dynein-related AAA-type ATPase, putative	0.0035	0.0015	0.0053
Echinococcus multilocularis	collagen alpha 1(VII) chain	0.0035	0.0015	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0101	0.0459	0.0799
Onchocerca volvulus		0.0035	0.0015	0.0009
Echinococcus multilocularis	Mitotic checkpoint protein PRCC, C terminal	0.0131	0.0662	0.0662
Echinococcus granulosus	allatostatin A receptor	0.0085	0.0351	0.0351
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Plasmodium falciparum	apical sushi protein	0.006	0.0184	0.0639
Leishmania major	aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1	0.0034	0.0012	0.018
Echinococcus multilocularis	allatostatin A receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Onchocerca volvulus		0.0035	0.0015	0.0009
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0074	0.0281	0.049
Schistosoma mansoni	acetylcholine receptor subunit beta	0.0074	0.0281	0.0281
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	Cation transporter family protein	0.0302	0.181	0.3152
Schistosoma mansoni	integrin alpha	0.0167	0.0904	0.0904
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0197	0.1103	0.1921
Plasmodium vivax	aspartyl protease, putative	0.0197	0.1108	0.3837
Echinococcus granulosus	peptidase s8 s53 subtilisin kexin sedolisin	0.0038	0.0037	0.0037
Brugia malayi	Peptidase family M1 containing protein	0.0034	0.0012	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Schistosoma mansoni	biogenic amine receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	neuropeptide receptor	0.0085	0.0351	0.0351
Trypanosoma cruzi	serine peptidase, Clan SC, Family S9B	0.0132	0.0668	1
Echinococcus granulosus	histone lysine n methyltransferase setd8	0.0066	0.0224	0.0224
Schistosoma mansoni	hypothetical protein	0.0033	0.0004	0.0004
Echinococcus granulosus	neuropeptide receptor A26	0.0085	0.0351	0.0351
Plasmodium falciparum	plasmepsin VI	0.0462	0.2887	1
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0085	0.0351	0.0351
Loa Loa (eye worm)	melatonin receptor type 1A	0.0085	0.0351	0.0612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0539	0.3405	1
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0583	0.3699	0.6442
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Plasmodium falciparum	plasmepsin VII	0.0118	0.0574	0.1988
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0164	0.0881	0.0881
Toxoplasma gondii	subtilisin SUB4	0.0038	0.0037	0.0128
Trypanosoma cruzi	Aminopeptidase M1, putative	0.0034	0.0012	0.018
Echinococcus multilocularis	aminopeptidase N	0.0116	0.0563	0.0563
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Plasmodium falciparum	subtilisin-like protease 1	0.0038	0.0037	0.0128
Leishmania major	silent information regulator 2, putative	0.0126	0.0629	0.9429
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0161	0.0864	0.0864
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Onchocerca volvulus		0.006	0.0184	0.0467
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0161	0.0864	0.1505
Schistosoma mansoni	adenoreceptor	0.0085	0.0351	0.0351
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.021	0.119	0.3495
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0037	0.0108
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.1521	1	1
Brugia malayi	sulfakinin receptor protein	0.0085	0.0351	0.0612
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0085	0.0351	0.0351
Plasmodium falciparum	subtilisin-like protease 2	0.0038	0.0037	0.0128
Echinococcus multilocularis	histone lysine n methyltransferase setd8	0.0066	0.0224	0.0224
Echinococcus granulosus	hypothetical protein	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Plasmodium vivax	aspartyl proteinase, putative	0.0462	0.2887	1
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	cyclin B	0.0042	0.0062	0.0062
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Mycobacterium ulcerans	membrane-anchored serine protease (mycosin), MycP4	0.0038	0.0037	0.5328
Trypanosoma brucei	unspecified product	0.0036	0.0023	0.0346
Trypanosoma brucei	Dipeptidyl-peptidase 8-like, putative	0.0132	0.0668	1
Echinococcus multilocularis	G protein coupled receptor 139	0.0943	0.6115	0.6115
Schistosoma mansoni	neuropeptide receptor	0.0085	0.0351	0.0351
Toxoplasma gondii	subtilisin SUB7	0.0038	0.0037	0.0128
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Brugia malayi	hypothetical protein	0.006	0.0184	0.0321
Echinococcus multilocularis	neuroendocrine convertase 2	0.0558	0.3528	0.3528
Echinococcus multilocularis	c4b binding protein beta chain	0.006	0.0184	0.0184
Trypanosoma brucei	serine peptidase, Clan SC, Family S9B	0.0132	0.0668	1
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0085	0.0351	0.0612
Echinococcus granulosus	dna polymerase kappa	0.0043	0.0069	0.0069
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0161	0.0864	0.0864
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Schistosoma mansoni	hypothetical protein	0.0035	0.0015	0.0015
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Schistosoma mansoni	thyroid hormone receptor	0.016	0.0857	0.0857
Schistosoma mansoni	biogenic amine receptor	0.0085	0.0351	0.0351
Trichomonas vaginalis	chromatin regulatory protein sir2, putative	0.0126	0.0629	0.1849
Leishmania major	subtilisin-like serine peptidase	0.0038	0.0037	0.0552
Toxoplasma gondii	eukaryotic aspartyl protease superfamily protein	0.0118	0.0574	0.1988
Loa Loa (eye worm)	hypothetical protein	0.0237	0.1372	0.2389
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Toxoplasma gondii	aspartyl proteinase (eimepsin), putative	0.0462	0.2887	1
Trichomonas vaginalis	WD repeat domain, putative	0.0137	0.0704	0.2067
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0043	0.0069	0.0203
Plasmodium vivax	aspartyl proteinase, putative	0.0118	0.0574	0.1988
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Toxoplasma gondii	subtilisin SUB9	0.0038	0.0037	0.0128
Onchocerca volvulus		0.0302	0.181	0.4877
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Onchocerca volvulus		0.0087	0.0365	0.0958
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0004	0.0006
Echinococcus granulosus	NAD dependent deacetylase sirtuin 3	0.0126	0.0629	0.0629
Treponema pallidum	hypothetical protein	0.0035	0.0015	0.5
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0161	0.0864	0.1505
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0085	0.0351	0.0351
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0161	0.0864	0.0864
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0164	0.0881	0.0881
Mycobacterium leprae	PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3)	0.0038	0.0037	0.5
Schistosoma mansoni	hypothetical protein	0.0085	0.0351	0.0351
Schistosoma mansoni	serine/threonine protein kinase	0.0098	0.0439	0.0439
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0161	0.0864	0.0864
Trypanosoma cruzi	dipeptidyl-peptidase 8-like serine peptidase	0.0132	0.0668	1
Loa Loa (eye worm)	hypothetical protein	0.0092	0.0401	0.0699
Plasmodium falciparum	plasmepsin II	0.0462	0.2887	1
Trypanosoma brucei	Silent information regulator 2 related protein 1	0.0126	0.0629	0.9429
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Mycobacterium ulcerans	DNA polymerase IV	0.0043	0.0069	1
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0161	0.0864	0.1505
Echinococcus multilocularis	neuropeptide receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0085	0.0351	0.0612
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0161	0.0864	0.0864
Loa Loa (eye worm)	aspartic protease BmAsp-2	0.0462	0.2887	0.5027
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Plasmodium falciparum	plasmepsin X	0.0197	0.1108	0.3837
Brugia malayi	hypothetical protein	0.0035	0.0015	0.0027
Loa Loa (eye worm)	endoprotease bli-4	0.0888	0.5743	1
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0583	0.3699	0.3699
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Brugia malayi	von Willebrand Factor	0.0035	0.0015	0.0027
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Echinococcus multilocularis	glycine receptor subunit beta	0.0161	0.0864	0.0864
Entamoeba histolytica	elongation factor-2 kinase, putative	0.0035	0.0015	0.0243
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.021	0.119	0.3495
Toxoplasma gondii	subtilisin SUB6	0.0038	0.0037	0.0128
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.021	0.119	0.3495
Toxoplasma gondii	aspartyl protease ASP1	0.0462	0.2887	1
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3)	0.0038	0.0037	1
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	chromatin regulatory protein sir2	0.014	0.072	0.072
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0118	0.0574	0.0999
Trypanosoma brucei	subtilisin peptidase	0.0038	0.0037	0.0552
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	Cation transporter family protein	0.0161	0.0864	0.1505
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.021	0.119	0.3495
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0161	0.0864	0.0864
Trypanosoma brucei	DNA polymerase IV, putative	0.0043	0.0069	0.1037
Loa Loa (eye worm)	aspartyl protease 6	0.0118	0.0574	0.0999
Onchocerca volvulus		0.0085	0.0351	0.092
Echinococcus granulosus	furin	0.0888	0.5743	0.5743
Toxoplasma gondii	subtilisin SUB1	0.0038	0.0037	0.0128
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0211	0.1196	0.2083
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Onchocerca volvulus		0.0085	0.0351	0.092
Schistosoma mansoni	nicotinic acetylcholine receptor alpha	0.0087	0.0365	0.0365
Brugia malayi	Pre-SET motif family protein	0.0211	0.1196	0.2083
Entamoeba histolytica	aminopeptidase, putative	0.0034	0.0012	0.0191
Loa Loa (eye worm)	hypothetical protein	0.0583	0.3699	0.6442
Schistosoma mansoni	subfamily S8B non-peptidase homologue (S08 family)	0.021	0.119	0.119
Loa Loa (eye worm)	CUTiclin family member	0.0035	0.0015	0.0027
Brugia malayi	neuropeptide F receptor	0.0085	0.0351	0.0612
Onchocerca volvulus		0.006	0.0184	0.0467
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0037	0.0064
Trichomonas vaginalis	cyclins, putative	0.0042	0.0062	0.0181
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Echinococcus granulosus	nAChR subunit	0.0161	0.0864	0.0864
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Echinococcus granulosus	G protein coupled receptor 139	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Trypanosoma brucei	mitotic cyclin 6	0.0042	0.0062	0.0925
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Echinococcus multilocularis	nAChR subunit	0.0161	0.0864	0.0864
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.021	0.119	0.3495
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Brugia malayi	Protein set-1	0.0066	0.0224	0.0391
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.0161	0.0864	0.1505
Echinococcus multilocularis	nAChR subunit	0.0087	0.0365	0.0365
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0161	0.0864	0.1505
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0161	0.0864	0.1505
Echinococcus granulosus	neuropeptide FF receptor 2	0.0085	0.0351	0.0351
Brugia malayi	Subtilase family protein	0.0038	0.0037	0.0064
Onchocerca volvulus		0.006	0.0184	0.0467
Schistosoma mansoni	chromatin regulatory protein sir2	0.0126	0.0629	0.0629
Echinococcus granulosus	chromatin regulatory protein sir2	0.0126	0.0629	0.0629
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0085	0.0351	0.0351
Trichomonas vaginalis	ubiquitin-conjugating enzyme E2, putative	0.0035	0.0015	0.0045
Echinococcus granulosus	integrin alpha ps	0.0036	0.0023	0.0023
Trypanosoma brucei	DNA polymerase IV, putative	0.0043	0.0069	0.1037
Brugia malayi	Hypothetical subtilase-type proteinase F21H12.6 in chromosome II	0.0038	0.0037	0.0064
Echinococcus granulosus	membrane bound transcription factor site 1	0.0038	0.0037	0.0037
Echinococcus granulosus	neuropeptide receptor	0.0085	0.0351	0.0351
Toxoplasma gondii	subtilisin SUB11	0.0038	0.0037	0.0128
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0085	0.0351	0.0351
Brugia malayi	endoprotease bli-4 precursor	0.0888	0.5743	1
Brugia malayi	hypothetical protein	0.006	0.0184	0.0321
Schistosoma mansoni	nAChR subunit	0.0161	0.0864	0.0864
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Schistosoma mansoni	hypothetical protein	0.0035	0.0015	0.0015
Brugia malayi	transcriptional regulator, Sir2 family protein	0.0126	0.0629	0.1096
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Mycobacterium tuberculosis	Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like)	0.0038	0.0037	1
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0074	0.0281	0.049
Loa Loa (eye worm)	neuropeptide F receptor	0.0085	0.0351	0.0612
Loa Loa (eye worm)	aminopeptidase N	0.0034	0.0012	0.0021
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Echinococcus multilocularis	neuropeptide receptor	0.0943	0.6115	0.6115
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	proprotein convertase 2	0.021	0.119	0.2072
Echinococcus multilocularis	dna polymerase kappa	0.0043	0.0069	0.0069
Echinococcus granulosus	tm gpcr rhodopsin	0.0085	0.0351	0.0351
Echinococcus granulosus	7TM GPCR rhodopsin	0.0085	0.0351	0.0351
Schistosoma mansoni	nAChR subunit	0.0161	0.0864	0.0864
Brugia malayi	Zona pellucida-like domain containing protein	0.0035	0.0015	0.0027
Schistosoma mansoni	amine GPCR	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0048	0.0106	0.0185
Echinococcus multilocularis	g-protein coupled receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	TYRA-2 protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0161	0.0864	0.0864
Schistosoma mansoni	biogenic amine receptor	0.0085	0.0351	0.0351
Echinococcus multilocularis	serotonin receptor	0.0085	0.0351	0.0351
Brugia malayi	G protein-coupled receptor F59B2.13	0.0085	0.0351	0.0612
Echinococcus multilocularis	Peptidase M1, membrane alanine aminopeptidase, N terminal	0.0034	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0082	0.0333	0.058
Echinococcus granulosus	tm gpcr rhodopsin	0.0085	0.0351	0.0351
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0161	0.0864	0.1505
Echinococcus granulosus	neuropeptides capa receptor	0.0085	0.0351	0.0351
Onchocerca volvulus		0.0302	0.181	0.4877
Schistosoma mansoni	nAChR subunit	0.0161	0.0864	0.0864
Loa Loa (eye worm)	hypothetical protein	0.0348	0.212	0.3692
Plasmodium vivax	von Willebrand factor A domain-related protein, putative	0.0035	0.0015	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.005	0.0117	0.0117
Trypanosoma brucei	Aminopeptidase M1, putative	0.0034	0.0012	0.018
Plasmodium vivax	hypothetical protein, conserved	0.0035	0.0015	0.0053
Schistosoma mansoni	neuropeptide F-like receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0044	0.0077
Echinococcus granulosus	proprotein convertase subtilisin:kexin type 5	0.0539	0.3405	0.3405
Echinococcus multilocularis	g protein coupled receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	pregnancy-associated plasma protein-E	0.006	0.0184	0.0321
Toxoplasma gondii	rhoptry neck protein RON1	0.006	0.0184	0.0639
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Echinococcus multilocularis	fmrfamide receptor	0.0085	0.0351	0.0351
Echinococcus multilocularis	dro:myosuppressin receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0161	0.0864	0.0864
Loa Loa (eye worm)	hypothetical protein	0.0302	0.181	0.3152
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0161	0.0864	0.1505
Trichomonas vaginalis	cyclin B, putative	0.0042	0.0062	0.0181
Schistosoma mansoni	growth hormone secretagogue receptor	0.0085	0.0351	0.0351
Echinococcus granulosus	g-protein coupled receptor	0.0085	0.0351	0.0351
Echinococcus granulosus	Mitotic checkpoint protein PRCC C terminal	0.0131	0.0662	0.0662
Schistosoma mansoni	cathepsin D (A01 family)	0.1295	0.8478	0.8478
Toxoplasma gondii	von Willebrand factor type A domain-containing protein	0.0035	0.0015	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Schistosoma mansoni	neuropeptide receptor	0.0943	0.6115	0.6115
Echinococcus multilocularis	integrin alpha ps	0.0075	0.0285	0.0285
Onchocerca volvulus		0.0085	0.0351	0.092
Brugia malayi	Acetylcholine receptor protein, alpha-like chain 1 precursor	0.0074	0.0281	0.049
Echinococcus multilocularis	sex peptide receptor	0.0085	0.0351	0.0351
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0074	0.0281	0.049
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0087	0.0365	0.0636
Echinococcus multilocularis	serotonin receptor	0.0085	0.0351	0.0351
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0085	0.0351	0.0612
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Echinococcus granulosus	G protein coupled receptor kinase 1	0.0088	0.0371	0.0371
Onchocerca volvulus		0.0302	0.181	0.4877
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0085	0.0351	0.0351
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0583	0.3699	0.6442
Echinococcus multilocularis	glycine receptor subunit beta	0.0161	0.0864	0.0864
Brugia malayi	hypothetical protein	0.0074	0.0281	0.049
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0048	0.0106	0.0185
Brugia malayi	Integrin alpha pat-2 precursor	0.0167	0.0904	0.1574
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0583	0.3699	0.3699
Loa Loa (eye worm)	hypothetical protein	0.0107	0.0502	0.0874
Trichomonas vaginalis	set domain proteins, putative	0.0239	0.1389	0.4081
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0085	0.0351	0.0351
Echinococcus granulosus	aminopeptidase N	0.0116	0.0563	0.0563
Brugia malayi	hypothetical protein	0.0101	0.0459	0.0799
Schistosoma mansoni	histone-lysine n-methyltransferase seto7	0.0066	0.0224	0.0224
Brugia malayi	neuroendocrine convertase 1 precursor	0.0558	0.3528	0.6143
Trichomonas vaginalis	cyclin B, putative	0.0042	0.0062	0.0181
Brugia malayi	hypothetical protein	0.0237	0.1372	0.2389
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0085	0.0351	0.0351
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Echinococcus granulosus	serotonin receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0161	0.0864	0.0864
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Schistosoma mansoni	nAChR subunit	0.0074	0.0281	0.0281
Treponema pallidum	76K protein	0.0035	0.0015	0.5
Toxoplasma gondii	subtilisin SUB12	0.0038	0.0037	0.0128
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Onchocerca volvulus		0.006	0.0184	0.0467
Echinococcus multilocularis		0.0716	0.459	0.459
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Echinococcus granulosus	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Loa Loa (eye worm)	WD40 repeat protein	0.0137	0.0704	0.1226
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0038	0.0037	0.0552
Schistosoma mansoni	hypothetical protein	0.0085	0.0351	0.0351
Schistosoma mansoni	hypothetical protein	0.0036	0.0023	0.0023
Schistosoma mansoni	dihydropyridine-sensitive l-type calcium channel	0.0035	0.0015	0.0015
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0161	0.0864	0.1505
Echinococcus granulosus	cyclin B	0.0042	0.0062	0.0062
Onchocerca volvulus		0.0074	0.0281	0.073
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0663	0.1155
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0085	0.0351	0.092
Trichomonas vaginalis	chromatin regulatory protein sir2, putative	0.014	0.072	0.2114
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	nAChR subunit	0.0161	0.0864	0.0864
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	hypothetical protein	0.0137	0.0704	0.0704
Loa Loa (eye worm)	hypothetical protein	0.0197	0.1103	0.1921
Brugia malayi	Serotonin receptor	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Toxoplasma gondii	subtilisin SUB5	0.0038	0.0037	0.0128
Toxoplasma gondii	subtilisin SUB8	0.0038	0.0037	0.0128
Brugia malayi	prolyl oligopeptidase family protein	0.0392	0.2416	0.4207
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0037	0.0108
Echinococcus granulosus	neuroendocrine convertase 2	0.0558	0.3528	0.3528
Schistosoma mansoni	integrin alpha-ps	0.0075	0.0285	0.0285
Loa Loa (eye worm)	hypothetical protein	0.0118	0.0574	0.0999
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	Dopamine receptor protein 2	0.0085	0.0351	0.0612
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Trypanosoma cruzi	cyclin, putative	0.0042	0.0062	0.0925
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Brugia malayi	larval opioid receptor	0.0085	0.0351	0.0612
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	hypothetical protein	0.0048	0.0106	0.0106
Echinococcus multilocularis	orexin receptor type 2	0.0085	0.0351	0.0351
Echinococcus granulosus	neuropeptide receptor	0.0943	0.6115	0.6115
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0085	0.0351	0.0612
Mycobacterium ulcerans	proline rich membrane-anchored mycosin MycP5	0.0038	0.0037	0.5328
Echinococcus granulosus	neuropeptides capa receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	transcriptional regulator	0.0126	0.0629	0.1096
Toxoplasma gondii	aspartyl protease ASP3	0.0197	0.1108	0.3837
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0035	0.0015	0.0027
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0085	0.0351	0.0612
Echinococcus granulosus	orexin receptor type 2	0.0085	0.0351	0.0351
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0074	0.0281	0.049
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Entamoeba histolytica	cyclin, putative	0.0042	0.0062	0.0981
Loa Loa (eye worm)	AGC/GRK/BARK protein kinase	0.0098	0.0439	0.0765
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0161	0.0864	0.0864
Schistosoma mansoni	amine GPCR	0.0085	0.0351	0.0351
Echinococcus multilocularis	beta adrenergic receptor kinase	0.0098	0.0439	0.0439
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Echinococcus granulosus	survival motor neuron protein 1	0.0237	0.1372	0.1372
Onchocerca volvulus		0.0161	0.0864	0.2312
Brugia malayi	NAD-dependent deacetylase SIRT1	0.014	0.072	0.1253
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Entamoeba histolytica	hypothetical protein, conserved	0.0035	0.0015	0.0243
Brugia malayi	Neuronal acetylcholine receptor protein, alpha-2 chain precursor	0.0074	0.0281	0.049
Trypanosoma cruzi	CYC2-like cyclin, putative	0.0042	0.0062	0.0925
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Brugia malayi	follicle stimulating hormone receptor	0.0085	0.0351	0.0612
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0302	0.181	0.181
Brugia malayi	Transmembrane cell adhesion receptor mua-3 precursor, putative	0.0035	0.0015	0.0027
Trichomonas vaginalis	cyclins, putative	0.0042	0.0062	0.0181
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0161	0.0864	0.1505
Mycobacterium ulcerans	DNA polymerase IV	0.0043	0.0069	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Giardia lamblia	G2/mitotic-specific cyclin B	0.0042	0.0062	0.0309
Echinococcus multilocularis	gamma aminobutyric acid receptor subunit	0.0074	0.0281	0.0281
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Trichomonas vaginalis	DNA polymerase eta, putative	0.0043	0.0069	0.0203
Giardia lamblia	High cysteine membrane protein Group 2	0.033	0.1997	1
Loa Loa (eye worm)	prolyl oligopeptidase	0.0392	0.2416	0.4207
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Plasmodium vivax	SET domain protein, putative	0.0066	0.0224	0.0777
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0023	0.004
Echinococcus granulosus	nAChR subunit	0.0087	0.0365	0.0365
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0085	0.0351	0.0351
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Trichomonas vaginalis	cyclin B, putative	0.0042	0.0062	0.0181
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Plasmodium falciparum	plasmepsin IV	0.0462	0.2887	1
Brugia malayi	Peptidase family M1 containing protein	0.0116	0.0563	0.0981
Echinococcus multilocularis	dipeptidyl aminopeptidaseprotein	0.0392	0.2416	0.2416
Brugia malayi	aspartic protease BmAsp-2, identical	0.0118	0.0574	0.0999
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Echinococcus multilocularis	integrin alpha 3	0.0128	0.0642	0.0642
Schistosoma mansoni	cathepsin D (A01 family)	0.1295	0.8478	0.8478
Onchocerca volvulus		0.0137	0.0704	0.1876
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0539	0.3405	1
Loa Loa (eye worm)	hypothetical protein	0.0066	0.0224	0.0391
Trypanosoma cruzi	subtilisin peptidase	0.0038	0.0037	0.0552
Plasmodium vivax	aspartyl protease, putative	0.0118	0.0574	0.1988
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0302	0.181	0.181
Echinococcus granulosus	biogenic amine 5HT receptor	0.0085	0.0351	0.0351
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Brugia malayi	ORL1-like opioid receptor	0.0085	0.0351	0.0612
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus multilocularis	integrin alpha ps	0.0036	0.0023	0.0023
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0085	0.0351	0.0351
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0085	0.0351	0.0351
Echinococcus granulosus	g protein coupled receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0085	0.0351	0.0612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Echinococcus multilocularis	Dipeptidyl peptidase 9	0.0132	0.0668	0.0668
Echinococcus multilocularis	neuropeptide Y receptor	0.0085	0.0351	0.0351
Plasmodium falciparum	plasmepsin IX	0.0197	0.1108	0.3837
Schistosoma mansoni	neurotransmitter gated ion channel	0.0074	0.0281	0.0281
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Leishmania major	aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1	0.0034	0.0012	0.018
Loa Loa (eye worm)	neuropeptide F receptor	0.0085	0.0351	0.0612
Echinococcus granulosus	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Trichomonas vaginalis	cyclins, putative	0.0042	0.0062	0.0181
Giardia lamblia	Furin precursor putative serine protease	0.0172	0.0935	0.4682
Echinococcus multilocularis	NAD dependent deacetylase sirtuin 1	0.014	0.072	0.072
Schistosoma mansoni	neuropeptide F-like receptor	0.0085	0.0351	0.0351
Echinococcus granulosus	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus multilocularis	neuropeptide receptor A26	0.0085	0.0351	0.0351
Brugia malayi	Dopamine receptor	0.0085	0.0351	0.0612
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0037	0.0108
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0037	0.0108
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Schistosoma mansoni	tripeptidyl-peptidase II (S08 family)	0.0038	0.0037	0.0037
Schistosoma mansoni	opsin-like receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	acetylcholine receptor-related	0.0074	0.0281	0.0281
Loa Loa (eye worm)	hypothetical protein	0.0302	0.181	0.3152
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Echinococcus granulosus	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.0888	0.5743	0.5743
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Echinococcus granulosus	glycine receptor subunit beta	0.0161	0.0864	0.0864
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0085	0.0351	0.0351
Trichomonas vaginalis	hypothetical protein	0.0172	0.0935	0.2746
Plasmodium vivax	subtilisin-like serine protease, putative	0.0038	0.0037	0.0128
Trichomonas vaginalis	chromatin regulatory protein sir2, putative	0.014	0.072	0.2114
Loa Loa (eye worm)	neuronal acetylcholine receptor protein	0.0074	0.0281	0.049
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0062	0.0108
Onchocerca volvulus		0.006	0.0184	0.0467
Loa Loa (eye worm)	ACC-1 protein	0.0161	0.0864	0.1505
Schistosoma mansoni	neuropeptide receptor	0.0085	0.0351	0.0351
Entamoeba histolytica	Sir2 family transcriptional regulator, putative	0.0126	0.0629	1
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Brugia malayi	putative neuropeptide receptor	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	hypothetical protein	0.0034	0.0012	0.0021
Schistosoma mansoni	thyroid hormone receptor	0.016	0.0857	0.0857
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0161	0.0864	0.0864
Brugia malayi	prolyl oligopeptidase family protein	0.0132	0.0668	0.1163
Plasmodium falciparum	plasmepsin I	0.0462	0.2887	1
Brugia malayi	hypothetical protein	0.0074	0.0281	0.049
Brugia malayi	GnHR receptor homolog	0.0085	0.0351	0.0612
Toxoplasma gondii	dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein	0.0132	0.0668	0.2312
Schistosoma mansoni	cytosol alanyl aminopeptidase (M01 family)	0.0034	0.0012	0.0012
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Plasmodium falciparum	SET domain protein, putative	0.0066	0.0224	0.0777
Mycobacterium tuberculosis	Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5)	0.0038	0.0037	1
Schistosoma mansoni	memapsin-2 (A01 family)	0.0118	0.0574	0.0574
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0085	0.0351	0.0351
Brugia malayi	G-protein coupled receptor	0.0085	0.0351	0.0612
Echinococcus granulosus	C type lectin domian containing protein	0.006	0.0184	0.0184
Plasmodium vivax	aspartyl protease, putative	0.0197	0.1108	0.3837
Onchocerca volvulus		0.0085	0.0351	0.092
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0038	0.0037	0.0552
Onchocerca volvulus		0.0035	0.0015	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0462	0.2887	0.5027
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Entamoeba histolytica	hypothetical protein	0.0087	0.0365	0.5801
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	hypothetical protein	0.0085	0.0351	0.0351
Echinococcus granulosus	gamma aminobutyric acid receptor subunit	0.0074	0.0281	0.0281
Loa Loa (eye worm)	hypothetical protein	0.0104	0.0482	0.084
Trichomonas vaginalis	neuroendocrine convertase 2 precursor, putative	0.0172	0.0935	0.2746
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Trypanosoma cruzi	metallo-peptidase, clan MA(E), family M1, putative	0.0034	0.0012	0.018
Loa Loa (eye worm)	CUTiclin-Like family member	0.0035	0.0015	0.0027
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Onchocerca volvulus		0.006	0.0184	0.0467
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0085	0.0351	0.0351
Trichomonas vaginalis	chromatin regulatory protein sir2, putative	0.014	0.072	0.2114
Plasmodium vivax	apical sushi protein, putative	0.006	0.0184	0.0639
Schistosoma mansoni	chromatin regulatory protein sir2	0.0126	0.0629	0.0629
Brugia malayi	G protein-coupled receptor	0.0085	0.0351	0.0612
Echinococcus multilocularis	survival motor neuron protein 1	0.0237	0.1372	0.1372
Loa Loa (eye worm)	LGC-31 protein	0.0161	0.0864	0.1505
Brugia malayi	Cation transporter family protein	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	Melatonin receptor type 1A	0.0085	0.0351	0.0612
Onchocerca volvulus	Putative nachr subunit	0.0583	0.3699	1
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0161	0.0864	0.0864
Plasmodium falciparum	circumsporozoite- and TRAP-related protein	0.0035	0.0015	0.0053
Plasmodium vivax	subtilisin-like protease 2, putative	0.0038	0.0037	0.0128
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Onchocerca volvulus		0.0085	0.0351	0.092
Echinococcus multilocularis	chromatin regulatory protein sir2	0.0126	0.0629	0.0629
Leishmania major	dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B	0.0132	0.0668	1
Echinococcus multilocularis	NAD dependent deacetylase sirtuin 3	0.0126	0.0629	0.0629
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0161	0.0864	0.1505
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Echinococcus multilocularis	voltage dependent calcium channel subunit	0.0035	0.0015	0.0015
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus granulosus	biogenic amine 5HT receptor	0.0085	0.0351	0.0351
Trypanosoma brucei	metallo-peptidase, Clan MA(E) Family M1	0.0034	0.0012	0.018
Brugia malayi	Dopamine receptor protein 1	0.0085	0.0351	0.0612
Brugia malayi	Zona pellucida-like domain containing protein	0.0035	0.0015	0.0027
Trypanosoma cruzi	Silent information regulator 2 related protein 1	0.0126	0.0629	0.9429
Schistosoma mansoni	myosin xvIII	0.0085	0.0351	0.0351
Brugia malayi	putative neuropeptide receptor NPR1	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Onchocerca volvulus		0.0074	0.0281	0.073
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Echinococcus multilocularis	membrane bound transcription factor site 1	0.0038	0.0037	0.0037
Brugia malayi	Membrane-bound transcription factor site-1 protease precursor	0.0038	0.0037	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0074	0.0281	0.0281
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0161	0.0864	0.0864
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0161	0.0864	0.1505
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0085	0.0351	0.0351
Schistosoma mansoni	opsin-like receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0583	0.3699	0.3699
Onchocerca volvulus		0.006	0.0184	0.0467
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0037	0.0108
Toxoplasma gondii	subtilisin SUB10	0.0038	0.0037	0.0128
Echinococcus granulosus	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Onchocerca volvulus		0.0161	0.0864	0.2312
Schistosoma mansoni	hypothetical protein	0.0172	0.0935	0.0935
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0085	0.0351	0.0351
Echinococcus granulosus	NAD dependent deacetylase sirtuin 1	0.014	0.072	0.072
Schistosoma mansoni	c4b-binding protein beta chain	0.006	0.0184	0.0184
Loa Loa (eye worm)	G-protein coupled receptor	0.0085	0.0351	0.0612
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Echinococcus multilocularis	fmrfamide receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	peptidase family M1 containing protein	0.0094	0.0414	0.0721
Echinococcus multilocularis	G protein coupled receptor kinase 1	0.0088	0.0371	0.0371
Brugia malayi	Integrin alpha cytoplasmic region family protein	0.0126	0.0631	0.1099
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.021	0.119	0.3495
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Leishmania major	CYC2-like cyclin, putative,cyclin 6, putative	0.0042	0.0062	0.0925
Onchocerca volvulus	Dipeptidyl peptidase family member 1 homolog	0.0392	0.2416	0.6519
Echinococcus granulosus	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Brugia malayi	Serotonin receptor	0.0085	0.0351	0.0612
Echinococcus granulosus	fmrfamide receptor	0.0085	0.0351	0.0351
Trichomonas vaginalis	chromatin regulatory protein sir2, putative	0.0126	0.0629	0.1849
Echinococcus granulosus	voltage dependent calcium channel subunit	0.0035	0.0015	0.0015
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0085	0.0351	0.0612
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0161	0.0864	0.0864
Schistosoma mansoni	subfamily S9B unassigned peptidase (S09 family)	0.0392	0.2416	0.2416
Plasmodium vivax	plasmepsin IV, putative	0.0462	0.2887	1
Echinococcus granulosus	g protein coupled receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0118	0.0574	0.0574
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Brugia malayi	hypothetical protein	0.006	0.0184	0.0321
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Onchocerca volvulus		0.0048	0.0106	0.0256
Echinococcus granulosus	Furin 1	0.021	0.119	0.119
Echinococcus granulosus	integrin alpha 3	0.0128	0.0642	0.0642
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0161	0.0864	0.0864
Trichomonas vaginalis	leucine-rich repeat protein, BspA family	0.0172	0.0935	0.2746
Echinococcus multilocularis	cathepsin d (lysosomal aspartyl protease)	0.0462	0.2887	0.2887
Echinococcus granulosus	integrin alpha ps	0.0075	0.0285	0.0285
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0161	0.0864	0.1505
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Plasmodium vivax	plasmepsin V, putative	0.0118	0.0574	0.1988
Echinococcus granulosus	neuropeptide s receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Brugia malayi	hypothetical protein	0.0074	0.0281	0.049
Echinococcus granulosus	neuropeptide Y receptor	0.0085	0.0351	0.0351
Giardia lamblia	Hypothetical protein	0.0126	0.0629	0.3152
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0085	0.0351	0.0351
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Brugia malayi	excitatory GABA receptor EXP-1A	0.0161	0.0864	0.1505
Onchocerca volvulus		0.0085	0.0351	0.092
Trichomonas vaginalis	chromatin regulatory protein sir2, putative	0.014	0.072	0.2114
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Echinococcus granulosus	glycine receptor subunit beta	0.0161	0.0864	0.0864
Echinococcus multilocularis	g protein coupled receptor	0.0085	0.0351	0.0351
Trypanosoma cruzi	Silent information regulator 2 related protein 1	0.0126	0.0629	0.9429
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Plasmodium vivax	thrombospondin-related anonymous protein	0.0035	0.0015	0.0053
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0085	0.0351	0.0351
Loa Loa (eye worm)	subtilase	0.0038	0.0037	0.0064
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0087	0.0365	0.0636
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Brugia malayi	hypothetical protein	0.0074	0.0281	0.049
Echinococcus multilocularis	g protein coupled receptor	0.0085	0.0351	0.0351
Schistosoma mansoni	chromatin regulatory protein sir2	0.0126	0.0629	0.0629
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Echinococcus granulosus	protein will die slowly	0.0137	0.0704	0.0704
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0085	0.0351	0.092
Echinococcus multilocularis	C type lectin domian containing protein	0.006	0.0184	0.0184
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0087	0.0365	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0038	0.0037	0.0037
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0161	0.0864	0.0864
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.0062	0.0108
Trypanosoma cruzi	cyclin 6, putative	0.0042	0.0062	0.0925
Brugia malayi	AKH receptor	0.0085	0.0351	0.0612
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0085	0.0351	0.0351
Echinococcus multilocularis	proprotein convertase subtilisin:kexin type 5	0.0539	0.3405	0.3405
Onchocerca volvulus		0.0085	0.0351	0.092
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0161	0.0864	0.1505
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0085	0.0351	0.0612
Plasmodium falciparum	plasmepsin V	0.0118	0.0574	0.1988
Echinococcus multilocularis	neuropeptides capa receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Onchocerca volvulus		0.0085	0.0351	0.092
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Echinococcus multilocularis	thyroid hormone receptor alpha	0.016	0.0857	0.0857
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0085	0.0351	0.0612
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4)	0.0038	0.0037	1
Onchocerca volvulus		0.0085	0.0351	0.092
Loa Loa (eye worm)	G-protein coupled receptor	0.0085	0.0351	0.0612
Onchocerca volvulus		0.0035	0.0015	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Plasmodium vivax	circumsporozoite- and TRAP-related protein, putative	0.0035	0.0015	0.0053
Giardia lamblia	NAD-dependent histone deacetylase Sir2	0.014	0.072	0.3604
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Trichomonas vaginalis	Clan MA, family M1, aminopeptidase N-like metallopeptidase	0.0034	0.0012	0.0035
Brugia malayi	proprotein convertase 2	0.0558	0.3528	0.6143
Trypanosoma brucei	DNA polymerase kappa, putative	0.0043	0.0069	0.1037
Plasmodium falciparum	von Willebrand factor A domain-related protein	0.0035	0.0015	0.0053
Toxoplasma gondii	subtilisin SUB2	0.0038	0.0037	0.0128
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Onchocerca volvulus		0.0161	0.0864	0.2312
Schistosoma mansoni	nAChR subunit	0.0161	0.0864	0.0864
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0085	0.0351	0.0351
Schistosoma mansoni	serine/threonine protein kinase	0.0098	0.0439	0.0439
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Onchocerca volvulus		0.006	0.0184	0.0467
Schistosoma mansoni	survival motor neuron protein	0.0048	0.0106	0.0106
Echinococcus multilocularis	neuropeptides capa receptor	0.0085	0.0351	0.0351
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0087	0.0365	0.0636
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0085	0.0351	0.0351
Onchocerca volvulus		0.0038	0.0037	0.0067
Loa Loa (eye worm)	hypothetical protein	0.006	0.0184	0.0321
Echinococcus granulosus	collagen alpha 1VII chain	0.0035	0.0015	0.0015
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Brugia malayi	GCC2 and GCC3 family protein	0.006	0.0184	0.0321
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0004	0.0006
Echinococcus multilocularis	neuropeptide s receptor	0.0085	0.0351	0.0351
Trypanosoma brucei	Aminopeptidase M1, putative	0.0034	0.0012	0.018
Echinococcus multilocularis	cyclin B	0.0042	0.0062	0.0062
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0085	0.0351	0.0612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Plasmodium vivax	subtilisin-like protease 1	0.0038	0.0037	0.0128
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Onchocerca volvulus		0.006	0.0184	0.0467
Brugia malayi	hypothetical protein	0.0118	0.0574	0.0999
Schistosoma mansoni	amine GPCR	0.0085	0.0351	0.0351
Echinococcus granulosus	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Onchocerca volvulus		0.0085	0.0351	0.092
Onchocerca volvulus		0.0085	0.0351	0.092
Schistosoma mansoni	nAChR subunit	0.0161	0.0864	0.0864
Trichomonas vaginalis	cyclin A, putative	0.0042	0.0062	0.0181
Loa Loa (eye worm)	hypothetical protein	0.0888	0.5743	1
Loa Loa (eye worm)	hypothetical protein	0.0074	0.0281	0.049
Onchocerca volvulus		0.0035	0.0015	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Echinococcus granulosus	dro:myosuppressin receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Entamoeba histolytica	hypothetical protein	0.0035	0.0015	0.0243
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0085	0.0351	0.0351
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0085	0.0351	0.0351
Schistosoma mansoni	hypothetical protein	0.0131	0.0662	0.0662
Trypanosoma cruzi	cyclin, putative	0.0042	0.0062	0.0925
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0085	0.0351	0.0351
Onchocerca volvulus		0.0085	0.0351	0.092
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0087	0.0365	0.0365
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0074	0.0281	0.049
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0365	0.0636
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0085	0.0351	0.0351
Echinococcus granulosus	c4b binding protein beta chain	0.006	0.0184	0.0184
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0085	0.0351	0.0351
Brugia malayi	Pepsin A precursor	0.0118	0.0574	0.0999
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0161	0.0864	0.1505
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Echinococcus granulosus	tm gpcr rhodopsin	0.0085	0.0351	0.0351
Onchocerca volvulus		0.0087	0.0365	0.0958
Schistosoma mansoni	nAChR subunit	0.0074	0.0281	0.0281
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0042	0.0062	0.0108
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Echinococcus multilocularis	Peptidase S8 S53, subtilisin kexin sedolisin	0.0038	0.0037	0.0037
Onchocerca volvulus		0.0085	0.0351	0.092
Echinococcus granulosus	cathepsin d lysosomal aspartyl protease	0.0462	0.2887	0.2887
Onchocerca volvulus		0.0074	0.0281	0.073
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0583	0.3699	0.3699
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0048	0.0106	0.0185
Echinococcus multilocularis	puromycin sensitive aminopeptidase	0.0034	0.0012	0.0012
Brugia malayi	hypothetical protein	0.0118	0.0574	0.0999
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0074	0.0281	0.0281
Loa Loa (eye worm)	von Willebrand factor type A domain-containing protein	0.0035	0.0015	0.0027
Schistosoma mansoni	nAChR subunit	0.0161	0.0864	0.0864
Brugia malayi	Will die slowly protein	0.0137	0.0704	0.1226
Echinococcus granulosus	7tm_1 domain containing protein	0.0085	0.0351	0.0351
Schistosoma mansoni	neurotransmitter gated ion channel	0.0074	0.0281	0.0281
Echinococcus multilocularis	protein will die slowly	0.0137	0.0704	0.0704
Trichomonas vaginalis	conserved hypothetical protein	0.0172	0.0935	0.2746
Echinococcus multilocularis	integrin alpha ps	0.0075	0.0285	0.0285
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0015	0.0027
Trypanosoma brucei	serine peptidase, clan SB, family S8-like protein	0.0038	0.0037	0.0552
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.0038	0.0037	0.0037
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0583	0.3699	0.3699
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Entamoeba histolytica	Sir2 family transcriptional regulator, putative	0.0126	0.0629	1
Toxoplasma gondii	aspartyl protease	0.0118	0.0574	0.1988
Leishmania major	cyclin	0.0042	0.0062	0.0925
Brugia malayi	G-protein coupled receptor	0.0085	0.0351	0.0612
Echinococcus granulosus	sex peptide receptor	0.0085	0.0351	0.0351
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Mycobacterium ulcerans	aminopeptidase N PepN	0.0034	0.0012	0.174
Brugia malayi	von Willebrand factor type A domain containing protein	0.0035	0.0015	0.0027
Loa Loa (eye worm)	integrin alpha pat-2	0.0258	0.1512	0.2632
Schistosoma mansoni	hypothetical protein	0.0085	0.0351	0.0351
Toxoplasma gondii	microneme protein MIC2	0.0035	0.0015	0.0053
Echinococcus multilocularis	Furin 1	0.021	0.119	0.119
Brugia malayi	Cyclin, N-terminal domain containing protein	0.0042	0.0062	0.0108
Onchocerca volvulus		0.006	0.0184	0.0467
Loa Loa (eye worm)	ACC-1 protein	0.0161	0.0864	0.1505
Schistosoma mansoni	amine GPCR	0.0085	0.0351	0.0351
Mycobacterium ulcerans	membrane-anchored mycosin MycP3	0.0038	0.0037	0.5328
Brugia malayi	aspartic protease BmAsp-1, identical	0.0118	0.0574	0.0999
Trichomonas vaginalis	cyclins, putative	0.0042	0.0062	0.0181
Brugia malayi	Eukaryotic aspartyl protease family protein	0.0118	0.0574	0.0999
Loa Loa (eye worm)	aspartic protease BmAsp-1	0.0118	0.0574	0.0999
Toxoplasma gondii	rhoptry neck protein RON9	0.006	0.0184	0.0639
Echinococcus multilocularis	neuropeptide Y receptor	0.0085	0.0351	0.0351
Onchocerca volvulus		0.0239	0.1389	0.3735
Brugia malayi	hypothetical protein	0.006	0.0184	0.0321
Schistosoma mansoni	dipeptidyl-peptidase 9 (S09 family)	0.0132	0.0668	0.0668
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0351	0.0612
Loa Loa (eye worm)	von Willebrand factor domain-containing protein	0.0035	0.0015	0.0027
Plasmodium falciparum	thrombospondin-related anonymous protein	0.0035	0.0015	0.0053
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit type	0.0074	0.0281	0.0281
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0161	0.0864	0.0864
Schistosoma mansoni	furin-1 (S08 family)	0.0386	0.2375	0.2375
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0038	0.0037	0.0108
Plasmodium falciparum	plasmepsin VIII, putative	0.0118	0.0574	0.1988
Loa Loa (eye worm)	hypothetical protein	0.0161	0.0864	0.1505
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0161	0.0864	0.0864
Brugia malayi	hypothetical protein	0.0085	0.0351	0.0612
Schistosoma mansoni	subfamily A1A unassigned peptidase (A01 family)	0.0462	0.2887	0.2887
Loa Loa (eye worm)	GABA receptor subunit	0.0087	0.0365	0.0636
Schistosoma mansoni	amine GPCR	0.0085	0.0351	0.0351
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0085	0.0351	0.0351
Entamoeba histolytica	hypothetical protein, conserved	0.0035	0.0015	0.0243
Schistosoma mansoni	opsin-like receptor	0.0085	0.0351	0.0351
Brugia malayi	Sushi domain	0.006	0.0184	0.0321

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL1620637

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1476957