Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hexokinase | 0.0666 | 1 | 1 |
Echinococcus multilocularis | hexokinase type 2 | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0206 | 0.2714 | 0.2699 |
Entamoeba histolytica | hexokinase 1 | 0.0666 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.0666 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0206 | 0.2714 | 0.2699 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0325 | 0.0305 |
Loa Loa (eye worm) | hexokinase | 0.0418 | 0.6069 | 0.606 |
Onchocerca volvulus | 0.0286 | 0.3981 | 0.3968 | |
Onchocerca volvulus | 0.0666 | 1 | 1 | |
Entamoeba histolytica | hexokinase 2 | 0.0666 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0454 | 0.6646 | 0.6639 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0251 | 0.3431 | 0.3417 |
Toxoplasma gondii | hexokinase | 0.0666 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0325 | 0.0305 |
Echinococcus multilocularis | hexokinase | 0.0666 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.0666 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.0418 | 0.6069 | 0.606 |
Loa Loa (eye worm) | hexokinase type II | 0.0666 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.0666 | 1 | 0.5 |
Onchocerca volvulus | 0.0666 | 1 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0325 | 0.0305 |
Leishmania major | hexokinase, putative | 0.0666 | 1 | 0.5 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0036 | 0.0021 | 0.0021 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0055 | 0.0325 | 0.0305 |
Brugia malayi | Hexokinase family protein | 0.0666 | 1 | 1 |
Onchocerca volvulus | Hexokinase homolog | 0.0418 | 0.6069 | 0.606 |
Trypanosoma brucei | hexokinase, putative | 0.0666 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.0666 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2804 | 0.2789 |
Echinococcus multilocularis | hexokinase | 0.0666 | 1 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0251 | 0.3431 | 0.3417 |
Echinococcus granulosus | hexokinase | 0.0666 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.0666 | 1 | 1 |
Plasmodium vivax | hexokinase, putative | 0.0666 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.0666 | 1 | 0.5 |
Plasmodium falciparum | hexokinase | 0.0666 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.0666 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0666 | 1 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.0666 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0055 | 0.0325 | 0.0305 |
Treponema pallidum | hexokinase (hxk) | 0.0666 | 1 | 0.5 |
Brugia malayi | hexokinase type II | 0.0212 | 0.2804 | 0.2789 |
Onchocerca volvulus | 0.0418 | 0.6069 | 0.606 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0325 | 0.0325 |
Onchocerca volvulus | 0.0666 | 1 | 1 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0055 | 0.0325 | 0.0305 |
Loa Loa (eye worm) | hexokinase | 0.0666 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2804 | 0.2789 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0055 | 0.0325 | 0.0325 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0055 | 0.0325 | 0.0305 |
Trichomonas vaginalis | set domain proteins, putative | 0.0286 | 0.3981 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.