Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0185 | 0.3483 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0185 | 0.3483 | 0.3483 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0127 | 0.1108 | 0.1108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0185 | 0.3483 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0185 | 0.3483 | 0.3483 |
Onchocerca volvulus | Cathepsin L homolog | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0127 | 0.1108 | 0.1108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0127 | 0.1108 | 0.3182 |
Plasmodium vivax | vivapain-2 | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Echinococcus granulosus | cathepsin b | 0.0344 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0127 | 0.1108 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.3483 | 0.3483 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0344 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0127 | 0.1108 | 0.1108 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0344 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0185 | 0.3483 | 1 |
Plasmodium vivax | vivapain-2 | 0.0185 | 0.3483 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0344 | 1 | 1 |
Onchocerca volvulus | 0.0185 | 0.3483 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0185 | 0.3483 | 0.3483 |
Echinococcus granulosus | cathepsin b | 0.0344 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0344 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.3483 | 0.3483 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0127 | 0.1108 | 0.1108 |
Onchocerca volvulus | 0.0185 | 0.3483 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.3483 | 0.3483 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1453 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0135 | 0.1453 | 0.1453 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0127 | 0.1108 | 0.1108 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0185 | 0.3483 | 0.3483 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0185 | 0.3483 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0344 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0185 | 0.3483 | 0.3483 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0127 | 0.1108 | 0.3182 |
Loa Loa (eye worm) | fibroinase | 0.0185 | 0.3483 | 0.2671 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0135 | 0.1453 | 0.4171 |
Loa Loa (eye worm) | cysteine protease | 0.0185 | 0.3483 | 0.2671 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1453 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0185 | 0.3483 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0127 | 0.1108 | 0.1108 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.3483 | 0.2671 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0185 | 0.3483 | 0.3483 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.3483 | 0.3483 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0185 | 0.3483 | 0.2671 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0344 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.3483 | 0.3483 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0185 | 0.3483 | 0.3483 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0344 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.3483 | 0.3483 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 0.1453 | 0.1453 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0185 | 0.3483 | 0.3483 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0185 | 0.3483 | 0.3483 |
Loa Loa (eye worm) | ctsf protein | 0.0185 | 0.3483 | 0.2671 |
Leishmania major | cysteine peptidase A (CPA) | 0.0185 | 0.3483 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0185 | 0.3483 | 0.3483 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0185 | 0.3483 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.3483 | 0.3483 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.3483 | 0.3483 |
Onchocerca volvulus | 0.0185 | 0.3483 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0135 | 0.1453 | 0.0387 |
Onchocerca volvulus | 0.0185 | 0.3483 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0344 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0185 | 0.3483 | 0.3483 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0185 | 0.3483 | 0.3483 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Onchocerca volvulus | 0.0185 | 0.3483 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0185 | 0.3483 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.3483 | 0.3483 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.3483 | 0.3483 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0185 | 0.3483 | 0.2671 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Onchocerca volvulus | 0.0185 | 0.3483 | 1 | |
Brugia malayi | cathepsin L-like precursor | 0.0127 | 0.1108 | 0.1108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.3483 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0135 | 0.1453 | 0.4171 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1453 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.3483 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0185 | 0.3483 | 0.3483 |
Toxoplasma gondii | cathepsin CPL | 0.0185 | 0.3483 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.3483 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.