Detailed information for compound 1478030

Basic information

Technical information
  • TDR Targets ID: 1478030
  • Name: 1-morpholin-4-ylpropan-2-yl benzoate
  • MW: 249.306 | Formula: C14H19NO3
  • H donors: 0 H acceptors: 1 LogP: 1.87 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(OC(=O)c1ccccc1)CN1CCOCC1
  • InChi: 1S/C14H19NO3/c1-12(11-15-7-9-17-10-8-15)18-14(16)13-5-3-2-4-6-13/h2-6,12H,7-11H2,1H3
  • InChiKey: GDXXTFIKRQSFJW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (1-methyl-2-morpholino-ethyl) benzoate
  • benzoic acid (1-methyl-2-morpholinoethyl) ester
  • benzoic acid (1-methyl-2-morpholino-ethyl) ester
  • STOCK3S-22412
  • Oprea1_740188

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi SWIRM domain containing protein 0.0146 0.0122 0.0118
Loa Loa (eye worm) hypothetical protein 0.0144 0.012 0.0116
Brugia malayi Kelch motif family protein 0.1417 0.1518 0.1514
Schistosoma mansoni integrin alpha-ps 0.0743 0.0778 0.1311
Echinococcus multilocularis protein kinase c epsilon type 0.0087 0.0057 0.0068
Loa Loa (eye worm) transcriptional regulator 0.0049 0.0017 0.0012
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0237 0.0222 0.0354
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.275 0.2982 1
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0049 0.0017 0.0226
Mycobacterium ulcerans membrane-anchored serine protease (mycosin), MycP4 0.0193 0.0175 0.4422
Echinococcus multilocularis NAD dependent deacetylase sirtuin 6 0.0049 0.0017 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.0228 0.0364
Schistosoma mansoni site-1 peptidase (S08 family) 0.0193 0.0175 0.0272
Mycobacterium ulcerans Sir2-like regulatory protein 0.0049 0.0017 0.0246
Toxoplasma gondii subtilisin SUB9 0.0193 0.0175 0.3988
Loa Loa (eye worm) glutamate receptor 1 0.0135 0.0111 0.0106
Trypanosoma cruzi subtilisin peptidase 0.0193 0.0175 0.4059
Echinococcus multilocularis membrane bound transcription factor site 1 0.0193 0.0175 0.0227
Brugia malayi Disintegrin family protein 0.0098 0.007 0.0065
Leishmania major ribonucleoside-diphosphate reductase large chain, putative 0.0416 0.0419 1
Echinococcus granulosus glutamate receptor 2 0.0081 0.0051 0.006
Echinococcus multilocularis GPCR, family 2 0.0063 0.0031 0.0032
Echinococcus multilocularis epidermal growth factor receptor 0.0116 0.009 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Loa Loa (eye worm) hypothetical protein 0.1406 0.1506 0.1502
Loa Loa (eye worm) hypothetical protein 0.0187 0.0168 0.0163
Entamoeba histolytica PH domain containing protein kinase, putative 0.0071 0.004 0.0744
Mycobacterium ulcerans polyketide synthase Pks9 0.0056 0.0024 0.0444
Echinococcus multilocularis glutamate receptor 2 0.0081 0.0051 0.006
Brugia malayi NAD-dependent deacetylase SIRT1 0.0049 0.0017 0.0012
Echinococcus granulosus integrin alpha 3 0.1071 0.1138 0.1537
Echinococcus granulosus serine:threonine protein kinase N2 0.0071 0.004 0.0044
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0073 0.0042 0.0047
Loa Loa (eye worm) transcriptional regulator 0.0335 0.033 0.0326
Loa Loa (eye worm) hypothetical protein 0.0135 0.0111 0.0106
Echinococcus multilocularis prolyl endopeptidase 0.0128 0.0103 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Plasmodium vivax plasmepsin IV, putative 0.0255 0.0242 0.5606
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0051 0.0018 0.0041
Toxoplasma gondii subtilisin SUB1 0.0193 0.0175 0.3988
Schistosoma mansoni integrin beta subunit 0.5337 0.5823 1
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0064 0.0032 0.0028
Echinococcus granulosus furin 0.4524 0.493 0.6689
Loa Loa (eye worm) hypothetical protein 0.0134 0.011 0.0105
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0128 0.0103 0.0149
Toxoplasma gondii aspartyl protease 0.0144 0.012 0.2655
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0069 0.0038 0.0818
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Wolbachia endosymbiont of Brugia malayi ribonucleotide-diphosphate reductase subunit alpha 0.0386 0.0386 0.5
Trypanosoma cruzi prolyl endopeptidase 0.0128 0.0103 0.2323
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Echinococcus granulosus NAD dependent deacetylase sirtuin 7 0.0049 0.0017 0.0013
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0092 0.0063 0.1474
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0193 0.0175 0.4496
Brugia malayi Integrin alpha pat-2 precursor 0.1458 0.1563 0.1559
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0144 0.012 0.0116
Schistosoma mansoni chromatin regulatory protein sir2 0.0335 0.033 0.0541
Schistosoma mansoni furin-1 (S08 family) 0.1968 0.2123 0.3628
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0064 0.0032 0.0027
Echinococcus granulosus integrin alpha ps 0.0807 0.0848 0.1143
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Brugia malayi proprotein convertase 2 0.2843 0.3084 0.3081
Plasmodium falciparum plasmepsin VI 0.0255 0.0242 0.5606
Toxoplasma gondii subtilisin SUB7 0.0193 0.0175 0.3988
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0087 0.0058 0.1454
Loa Loa (eye worm) hypothetical protein 0.0065 0.0034 0.0029
Schistosoma mansoni dihydroceramide desaturase 0.0098 0.007 0.0092
Loa Loa (eye worm) hypothetical protein 0.0187 0.0168 0.0163
Schistosoma mansoni integrin alpha-ps 0.0451 0.0457 0.0759
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0069 0.0038 0.0544
Loa Loa (eye worm) endoprotease bli-4 0.4524 0.493 0.4928
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0056 0.0024 0.0159
Loa Loa (eye worm) hypothetical protein 0.0047 0.0014 0.0009
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0204 0.0187 0.4355
Trypanosoma cruzi Silent information regulator 2 related protein 3 0.0049 0.0017 0.0226
Schistosoma mansoni protein kinase 0.0142 0.0118 0.0174
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0087 0.0057 0.1443
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0124 0.0098 0.0094
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.0049 0.0017 0.0013
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0092 0.0064 0.1603
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0007 0.0172
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0064 0.0032 0.0034
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Schistosoma mansoni hypothetical protein 0.0875 0.0923 0.1561
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0242 0.0228 0.0223
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.1069 0.1135 0.1927
Trypanosoma brucei ribonucleoside-diphosphate reductase large chain 0.0416 0.0419 1
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0118 0.0092 0.2059
Toxoplasma gondii subtilisin SUB5 0.0193 0.0175 0.3988
Brugia malayi Reprolysin 0.0139 0.0114 0.011
Brugia malayi transcriptional regulator, Sir2 family protein 0.0335 0.033 0.0326
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Leishmania major silent information regulator 2, putative 0.0335 0.033 0.7791
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0187 0.0168 0.0539
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0193 0.0175 0.4496
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.007 0.0039 0.0974
Brugia malayi ribonucleoside-diphosphate reductase large chain, putative 0.0416 0.0419 0.0415
Loa Loa (eye worm) hypothetical protein 0.0237 0.0222 0.0218
Echinococcus granulosus neuroendocrine convertase 2 0.2843 0.3084 0.4181
Echinococcus granulosus lysine specific histone demethylase 1A 0.0134 0.011 0.0139
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0154 0.0131 0.0168
Schistosoma mansoni cathepsin D (A01 family) 0.0539 0.0554 0.0926
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0131 0.0106 0.2716
Toxoplasma gondii aspartyl protease ASP3 0.0144 0.012 0.2655
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0672 0.07 0.0941
Echinococcus multilocularis ribonucleoside diphosphate reductase large 0.0416 0.0419 0.056
Loa Loa (eye worm) hypothetical protein 0.1775 0.1911 0.1907
Toxoplasma gondii aspartyl protease ASP1 0.0255 0.0242 0.5654
Plasmodium vivax aspartyl protease, putative 0.0144 0.012 0.2574
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0335 0.033 0.7841
Schistosoma mansoni protein kinase 0.0142 0.0118 0.0174
Loa Loa (eye worm) hypothetical protein 0.042 0.0423 0.0419
Echinococcus granulosus membrane bound transcription factor site 1 0.0193 0.0175 0.0227
Schistosoma mansoni hypothetical protein 0.0356 0.0353 0.058
Echinococcus granulosus nmda type glutamate receptor 0.0164 0.0143 0.0184
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0175 0.0562
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0198 0.018 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0175 0.0562
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Loa Loa (eye worm) hypothetical protein 0.0715 0.0748 0.0743
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1069 0.1135 0.3793
Giardia lamblia Neurogenic locus Notch protein precursor 0.0187 0.0168 0.0843
Brugia malayi Subtilase family protein 0.0193 0.0175 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Plasmodium falciparum plasmepsin III 0.0144 0.012 0.2574
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0237 0.0222 0.0292
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0063 0.0031 0.0032
Brugia malayi prolyl oligopeptidase family protein 0.0128 0.0103 0.0098
Brugia malayi EGF-like domain containing protein 0.0187 0.0168 0.0163
Plasmodium falciparum subtilisin-like protease 2 0.0193 0.0175 0.3922
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Mycobacterium leprae Possible secreted protease 0.0193 0.0175 0.4256
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0335 0.033 0.7841
Schistosoma mansoni site-1 peptidase (S08 family) 0.0193 0.0175 0.0272
Brugia malayi aspartic protease BmAsp-1, identical 0.0144 0.012 0.0116
Loa Loa (eye worm) transcriptional regulator 0.0049 0.0017 0.0012
Giardia lamblia Tenascin-X 0.0187 0.0168 0.0843
Brugia malayi aspartic protease BmAsp-2, identical 0.0144 0.012 0.0116
Mycobacterium ulcerans proline rich membrane-anchored mycosin MycP5 0.0193 0.0175 0.4422
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1069 0.1135 0.3793
Schistosoma mansoni chromatin regulatory protein sir2 0.0335 0.033 0.0541
Schistosoma mansoni glutamate receptor AMPA 0.0135 0.0111 0.0163
Plasmodium falciparum plasmepsin I 0.0255 0.0242 0.5606
Mycobacterium leprae Probable polyketide synthase Pks1 0.0092 0.0064 0.1236
Echinococcus multilocularis integrin alpha ps 0.0356 0.0353 0.047
Echinococcus granulosus Furin 1 0.1069 0.1135 0.1533
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.275 0.2982 1
Loa Loa (eye worm) hypothetical protein 0.4524 0.493 0.4928
Toxoplasma gondii ribonucleoside-diphosphate reductase large chain 0.0416 0.0419 1
Schistosoma mansoni ribonucleoside-diphosphate reductase alpha subunit 0.0416 0.0419 0.0694
Loa Loa (eye worm) apoptosis regulator protein 0.0064 0.0032 0.0028
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0193 0.0175 0.0272
Echinococcus granulosus adam 0.0497 0.0508 0.068
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0051 0.0018 0.0266
Giardia lamblia High cysteine membrane protein Group 2 0.1681 0.1808 1
Loa Loa (eye worm) hypothetical protein 0.0148 0.0125 0.012
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0335 0.033 0.7878
Echinococcus multilocularis fibrillin 1 0.0187 0.0168 0.0218
Plasmodium falciparum plasmepsin IX 0.0144 0.012 0.2574
Loa Loa (eye worm) hypothetical protein 0.0098 0.007 0.0065
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Echinococcus multilocularis disintegrin and metalloproteinase 0.0098 0.007 0.0085
Brugia malayi Stress-activated protein kinase jnk-1 0.0242 0.0228 0.0223
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0087 0.0057 0.0053
Leishmania major oligopeptidase b 0.0051 0.0018 0.0041
Schistosoma mansoni cathepsin D (A01 family) 0.0539 0.0554 0.0926
Loa Loa (eye worm) integrin beta-2 0.9142 1 1
Echinococcus granulosus protein kinase c epsilon type 0.0087 0.0057 0.0068
Trichomonas vaginalis hypothetical protein 0.0875 0.0923 0.3079
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0128 0.0103 0.2146
Onchocerca volvulus Fatty acid synthase homolog 0.0162 0.014 0.7833
Plasmodium vivax subtilisin-like serine protease, putative 0.0193 0.0175 0.3922
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.4524 0.493 0.8463
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Loa Loa (eye worm) kelch domain-containing protein family protein 0.1417 0.1518 0.1514
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0255 0.0242 0.032
Schistosoma mansoni hypothetical protein 0.0064 0.0032 0.0027
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Brugia malayi transcriptional regulator, Sir2 family protein 0.0049 0.0017 0.0012
Giardia lamblia High cysteine protein 0.0187 0.0168 0.0843
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0154 0.0131 0.0168
Echinococcus granulosus adam 17 protease 0.0098 0.007 0.0085
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0092 0.0064 0.149
Schistosoma mansoni glutamate receptor AMPA 0.0135 0.0111 0.0163
Onchocerca volvulus Prolyl endopeptidase homolog 0.0128 0.0103 0.5495
Toxoplasma gondii type I fatty acid synthase, putative 0.0092 0.0064 0.1264
Echinococcus multilocularis glutamate receptor 2 0.0154 0.0131 0.0168
Loa Loa (eye worm) hypothetical protein 0.0146 0.0122 0.0118
Mycobacterium tuberculosis Transcriptional regulatory protein 0.0049 0.0017 0.0376
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Mycobacterium ulcerans membrane-anchored mycosin MycP3 0.0193 0.0175 0.4422
Loa Loa (eye worm) aspartyl protease 6 0.0144 0.012 0.0116
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Loa Loa (eye worm) acyl carrier protein 0.0041 0.0008 0.0003
Mycobacterium ulcerans polyketide synthase 0.0092 0.0064 0.149
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.0098 0.007 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0087 0.0057 0.1443
Echinococcus multilocularis integrin alpha ps 0.0807 0.0848 0.1143
Loa Loa (eye worm) ribonucleoside-diphosphate reductase large subunit 0.0416 0.0419 0.0415
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0335 0.033 0.1087
Plasmodium falciparum ribonucleoside-diphosphate reductase large subunit, putative 0.0416 0.0419 1
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0335 0.033 1
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Plasmodium vivax subtilisin-like protease 2, putative 0.0193 0.0175 0.3922
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Brugia malayi ADAMTS-like protease 0.0138 0.0114 0.011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1069 0.1135 0.3793
Loa Loa (eye worm) hypothetical protein 0.1102 0.1172 0.1168
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0075 0.0044 0.0715
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0084 0.0054 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Brugia malayi hypothetical protein 0.0144 0.012 0.0116
Mycobacterium ulcerans thioesterase TesA 0.0075 0.0044 0.0984
Brugia malayi neuroendocrine convertase 1 precursor 0.2843 0.3084 0.3081
Toxoplasma gondii subtilisin SUB4 0.0193 0.0175 0.3988
Trypanosoma brucei subtilisin peptidase 0.0193 0.0175 0.4161
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Toxoplasma gondii prolyl endopeptidase 0.0128 0.0103 0.2231
Loa Loa (eye worm) hypothetical protein 0.0187 0.0168 0.0163
Echinococcus granulosus glutamate receptor 2 0.0154 0.0131 0.0168
Mycobacterium tuberculosis Probable thioesterase TesA 0.0075 0.0044 0.1104
Trypanosoma cruzi oligopeptidase b 0.0051 0.0018 0.0266
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0672 0.07 0.0941
Echinococcus multilocularis integrin beta 2 0.6743 0.7367 1
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Schistosoma mansoni tyrosine kinase 0.0116 0.009 0.0126
Giardia lamblia Hypothetical protein 0.0335 0.033 0.1752
Plasmodium falciparum plasmepsin V 0.0376 0.0375 0.8904
Loa Loa (eye worm) hypothetical protein 0.0138 0.0114 0.011
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0144 0.012 0.2655
Brugia malayi Furin-like cysteine rich region family protein 0.0116 0.009 0.0085
Schistosoma mansoni glutamate receptor kainate 0.0135 0.0111 0.0163
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0335 0.033 1
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.275 0.2982 0.4042
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0051 0.0018 0.0266
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0164 0.0143 0.0184
Trypanosoma brucei SIR2-like protein 4, putative 0.0049 0.0017 0.0394
Loa Loa (eye worm) hypothetical protein 0.0064 0.0032 0.0028
Echinococcus multilocularis neuroendocrine convertase 2 0.2843 0.3084 0.4181
Loa Loa (eye worm) hypothetical protein 0.1011 0.1072 0.1068
Brugia malayi EGF-like domain containing protein 0.0187 0.0168 0.0163
Schistosoma mansoni integrin alpha 0.1458 0.1563 0.2664
Giardia lamblia Neurogenic locus notch-like protein 0.0187 0.0168 0.0843
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0154 0.0131 0.0168
Loa Loa (eye worm) hypothetical protein 0.0064 0.0033 0.0028
Loa Loa (eye worm) hypothetical protein 0.0255 0.0242 0.0238
Schistosoma mansoni hypothetical protein 0.0064 0.0032 0.0027
Loa Loa (eye worm) hypothetical protein 0.0807 0.0848 0.0844
Loa Loa (eye worm) hypothetical protein 0.0451 0.0457 0.0453
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.0049 0.0017 0.0013
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0204 0.0187 0.4452
Echinococcus multilocularis protein jagged 2 0.0187 0.0168 0.0218
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0167 0.0146 0.0141
Schistosoma mansoni glutamate receptor NMDA 0.0154 0.0131 0.0197
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0128 0.0103 0.0149
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0801 0.0841 0.1133
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0065 0.0033 0.0808
Loa Loa (eye worm) reprolysin 0.0237 0.0222 0.0218
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0875 0.0923 0.3079
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0237 0.0222 0.0292
Onchocerca volvulus 0.0156 0.0134 0.7447
Echinococcus granulosus c-Jun N-terminal kinases 0.0242 0.0228 0.03
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0064 0.0032 0.0034
Brugia malayi Integrin alpha cytoplasmic region family protein 0.1011 0.1072 0.1068
Plasmodium falciparum plasmepsin VIII, putative 0.0144 0.012 0.2574
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0087 0.0057 0.1069
Schistosoma mansoni hypothetical protein 0.0064 0.0032 0.0027
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0235 0.022 0.0351
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0154 0.0131 0.0168
Schistosoma mansoni apoptosis regulator bax 0.0064 0.0032 0.0027
Echinococcus multilocularis 0.3649 0.3969 0.5384
Mycobacterium ulcerans polyketide synthase Pks13 0.0131 0.0106 0.2618
Plasmodium falciparum plasmepsin II 0.0255 0.0242 0.5606
Schistosoma mansoni hypothetical protein 0.0135 0.0111 0.0162
Loa Loa (eye worm) metalloprotease 0.0065 0.0034 0.0029
Mycobacterium ulcerans polyketide synthase 0.0087 0.0057 0.1328
Toxoplasma gondii histone deacetylase SIR2-like 0.0049 0.0017 0.0109
Echinococcus multilocularis NMDA receptor 0.0073 0.0042 0.0047
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Trypanosoma brucei prolyl endopeptidase 0.0128 0.0103 0.2455
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0175 0.0562
Echinococcus granulosus disintegrin and metalloproteinase 0.0098 0.007 0.0085
Plasmodium vivax aspartyl protease, putative 0.0144 0.012 0.2574
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0092 0.0064 0.1603
Trichomonas vaginalis hypothetical protein 0.0187 0.0168 0.0539
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0134 0.011 0.0139
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0204 0.0187 0.4355
Plasmodium falciparum subtilisin-like protease 3 0.0193 0.0175 0.3922
Plasmodium vivax aspartyl proteinase, putative 0.0144 0.012 0.2574
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0134 0.011 0.0161
Echinococcus multilocularis Furin 1 0.1069 0.1135 0.1533
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.275 0.2982 0.4042
Echinococcus granulosus fibrillin 1 0.0187 0.0168 0.0218
Plasmodium falciparum plasmepsin IV 0.0255 0.0242 0.5606
Brugia malayi Latrophilin receptor protein 2 0.0063 0.0031 0.0026
Leishmania major subtilisin-like serine peptidase 0.0193 0.0175 0.3922
Echinococcus granulosus chromatin regulatory protein sir2 0.0335 0.033 0.0439
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0193 0.0175 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Echinococcus granulosus fibrillin 2 0.0187 0.0168 0.0218
Mycobacterium ulcerans thioesterase 0.0075 0.0044 0.0984
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0193 0.0175 0.4059
Schistosoma mansoni ATP-binding cassette transporter 0.0138 0.0114 0.0168
Plasmodium falciparum plasmepsin VII 0.0144 0.012 0.2574
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0056 0.0024 0.0444
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1292 0.138 0.2349
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0073 0.0042 0.0047
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0087 0.0057 0.1328
Echinococcus multilocularis nmda type glutamate receptor 0.0164 0.0143 0.0184
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0335 0.033 0.0439
Loa Loa (eye worm) glutamate receptor 2 0.0135 0.0111 0.0106
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Schistosoma mansoni glutamate receptor kainate 0.0135 0.0111 0.0163
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0193 0.0175 0.4256
Brugia malayi Glutamate receptor 2 precursor 0.0135 0.0111 0.0106
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0073 0.0042 0.0047
Brugia malayi hypothetical protein 0.031 0.0302 0.0298
Brugia malayi AMP-binding enzyme family protein 0.0084 0.0054 0.005
Echinococcus granulosus glutamate NMDA receptor subunit 0.0402 0.0403 0.0538
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Brugia malayi hypothetical protein 0.1406 0.1506 0.1502
Toxoplasma gondii aspartyl protease ASP5 0.0232 0.0217 0.5036
Brugia malayi Eukaryotic aspartyl protease family protein 0.0144 0.012 0.0116
Loa Loa (eye worm) angiogenesis inhibito 0.0065 0.0034 0.0029
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0193 0.0175 0.4496
Loa Loa (eye worm) hypothetical protein 0.0128 0.0103 0.0098
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0142 0.0118 0.015
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0092 0.0064 0.1603
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0092 0.0064 0.1236
Loa Loa (eye worm) fatty acid synthase 0.0089 0.006 0.0055
Mycobacterium tuberculosis Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) 0.0386 0.0386 1
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0073 0.0042 0.0047
Brugia malayi Pepsin A precursor 0.0144 0.012 0.0116
Brugia malayi EGF-like domain containing protein 0.0187 0.0168 0.0163
Plasmodium vivax aspartyl protease, putative 0.0144 0.012 0.2574
Plasmodium vivax ribonucleoside-diphosphate reductase large chain, putative 0.0416 0.0419 1
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0051 0.0018 0.0422
Onchocerca volvulus 0.0144 0.012 0.6581
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0092 0.0063 0.1587
Brugia malayi protein kinase C II. 0.0087 0.0057 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Echinococcus granulosus GPCR family 2 0.0063 0.0031 0.0032
Mycobacterium tuberculosis Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) 0.0139 0.0114 0.2929
Giardia lamblia hypothetical protein 0.0187 0.0168 0.0843
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1069 0.1135 0.3793
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0335 0.033 0.0439
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0087 0.0057 0.1069
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0154 0.0131 0.0168
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0051 0.0018 0.0419
Echinococcus multilocularis adam 0.0497 0.0508 0.068
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0335 0.033 0.1087
Loa Loa (eye worm) proprotein convertase 2 0.1069 0.1135 0.1131
Mycobacterium ulcerans ribonucleotide-diphosphate reductase subunit alpha 0.0386 0.0386 1
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.031 0.0302 0.0492
Echinococcus multilocularis serine:threonine protein kinase N2 0.0079 0.0049 0.0057
Echinococcus multilocularis fibrillin 2 0.0187 0.0168 0.0218
Mycobacterium tuberculosis Probable peptidase 0.0051 0.0018 0.0419
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0087 0.0058 0.1454
Loa Loa (eye worm) hypothetical protein 0.0134 0.011 0.0105
Giardia lamblia Tenascin-37 0.0187 0.0168 0.0843
Brugia malayi metalloprotease 0.0065 0.0034 0.0029
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0073 0.0042 0.0047
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0193 0.0175 0.4496
Schistosoma mansoni hypothetical protein 0.0063 0.0031 0.0025
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Brugia malayi EGF-like domain containing protein 0.0187 0.0168 0.0163
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Echinococcus granulosus glutamate receptor subunit protein glur 0.0073 0.0042 0.0047
Brugia malayi angiogenesis inhibito 0.0138 0.0114 0.011
Echinococcus granulosus NAD dependent deacetylase sirtuin 6 0.0049 0.0017 0.0013
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Echinococcus granulosus epidermal growth factor receptor 0.0116 0.009 0.0112
Giardia lamblia High cysteine protein 0.0187 0.0168 0.0843
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0242 0.0228 0.03
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0801 0.0841 0.1133
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0058 0.0026 0.0347
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0069 0.0038 0.0818
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0193 0.0175 0.0272
Loa Loa (eye worm) integrin alpha pat-2 0.2048 0.2211 0.2208
Trypanosoma brucei prolyl oligopeptidase, putative 0.0051 0.0018 0.0434
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0124 0.0098 0.0094
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0193 0.0175 0.0227
Echinococcus granulosus ribonucleoside diphosphate reductase large 0.0416 0.0419 0.056
Giardia lamblia Tenascin precursor 0.0187 0.0168 0.0843
Echinococcus multilocularis glutamate receptor 2 0.0135 0.0111 0.0141
Loa Loa (eye worm) hypothetical protein 0.0187 0.0168 0.0163
Loa Loa (eye worm) hypothetical protein 0.0193 0.0175 0.017
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0007 0.0172
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0051 0.0018 0.029
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0051 0.0018 0.0434
Plasmodium vivax subtilisin-like protease 1 0.0193 0.0175 0.3922
Schistosoma mansoni hypothetical protein 0.0063 0.0031 0.0025
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0087 0.0057 0.1443
Loa Loa (eye worm) hypothetical protein 0.0138 0.0114 0.011
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0084 0.0054 0.1364
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.0098 0.007 0.0085
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0115 0.0088 0.2245
Schistosoma mansoni memapsin-2 (A01 family) 0.2219 0.2399 0.4103
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Loa Loa (eye worm) latrophilin receptor protein 2 0.0063 0.0031 0.0026
Toxoplasma gondii subtilisin SUB6 0.0193 0.0175 0.3988
Schistosoma mansoni ADAMTS14 peptidase (M12 family) 0.0065 0.0034 0.003
Trypanosoma brucei Silent information regulator 2 related protein 3 0.0049 0.0017 0.0394
Mycobacterium leprae RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) 0.0386 0.0386 1
Onchocerca volvulus 0.0193 0.0175 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0087 0.0057 0.1328
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0092 0.0064 0.149
Toxoplasma gondii histone deacetylase SIR2 0.0049 0.0017 0.0109
Onchocerca volvulus 0.0187 0.0168 0.9562
Plasmodium vivax aspartyl proteinase, putative 0.0255 0.0242 0.5606
Plasmodium vivax plasmepsin V, putative 0.0376 0.0375 0.8904
Toxoplasma gondii subtilisin SUB12 0.0193 0.0175 0.3988
Loa Loa (eye worm) hypothetical protein 0.0049 0.0017 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0255 0.0242 0.0389
Toxoplasma gondii hypothetical protein 0.0187 0.0168 0.3817
Giardia lamblia Tenascin-like 0.0187 0.0168 0.0843
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0087 0.0057 0.0053
Schistosoma mansoni chromatin regulatory protein sir2 0.0335 0.033 0.0541
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0193 0.0175 0.0227
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0255 0.0242 0.5654
Brugia malayi Calcitonin receptor-like protein seb-1 0.0198 0.018 0.0175
Toxoplasma gondii subtilisin SUB11 0.0193 0.0175 0.3988
Giardia lamblia Furin precursor putative serine protease 0.0875 0.0923 0.506
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0193 0.0175 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0057 0.007
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0154 0.0131 0.0168
Toxoplasma gondii type I fatty acid synthase, putative 0.0064 0.0032 0.05
Brugia malayi Glutamate receptor 1 precursor 0.0135 0.0111 0.0106
Treponema pallidum ribonucleotide-diphosphate reductase subunit alpha 0.0416 0.0419 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1069 0.1135 0.3793
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0255 0.0242 0.032
Brugia malayi hypothetical protein 0.0144 0.012 0.0116
Mycobacterium leprae Polyketide synthase Pks13 0.0131 0.0106 0.2398
Trypanosoma cruzi oligopeptidase b 0.0051 0.0018 0.0266
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0144 0.012 0.0116
Echinococcus granulosus integrin alpha ps 0.0356 0.0353 0.047
Toxoplasma gondii subtilisin SUB8 0.0193 0.0175 0.3988
Schistosoma mansoni protein kinase 0.0142 0.0118 0.0174
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0875 0.0923 0.3079
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.1069 0.1135 0.3793
Onchocerca volvulus 0.0146 0.0122 0.671
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0154 0.0131 0.0168
Plasmodium falciparum plasmepsin X 0.0144 0.012 0.2574
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Echinococcus multilocularis integrin alpha 3 0.1071 0.1138 0.1537
Loa Loa (eye worm) subtilase 0.0193 0.0175 0.017
Echinococcus granulosus integrin beta 2 0.6743 0.7367 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0154 0.0131 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0402 0.0403 0.0538
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0073 0.0042 0.0047
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0063 0.0031 0.0032
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Trypanosoma brucei oligopeptidase b 0.0051 0.0018 0.0434
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0142 0.0118 0.015
Echinococcus granulosus prolyl endopeptidase 0.0128 0.0103 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0175 0.0562
Chlamydia trachomatis ribonucleoside-diphosphate reductase subunit alpha 0.0416 0.0419 1
Mycobacterium ulcerans Type I modular polyketide synthase 0.0087 0.0057 0.1328
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0092 0.0064 0.1236
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0063 0.0031 0.0026
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0193 0.0175 0.4256
Schistosoma mansoni glutamate receptor NMDA 0.0402 0.0403 0.0666
Schistosoma mansoni glutamate receptor kainate 0.0135 0.0111 0.0163
Mycobacterium ulcerans Type I modular polyketide synthase 0.0087 0.0057 0.1328
Schistosoma mansoni hypothetical protein 0.0063 0.0031 0.0025
Schistosoma mansoni hypothetical protein 0.0063 0.0031 0.0025
Loa Loa (eye worm) hypothetical protein 0.0063 0.0031 0.0026
Loa Loa (eye worm) sirtuin 4 0.0049 0.0017 0.0012
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0237 0.0222 0.0354
Echinococcus multilocularis NAD dependent deacetylase sirtuin 7 0.0049 0.0017 0.0013
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0807 0.0848 0.0844
Loa Loa (eye worm) hypothetical protein 0.0073 0.0042 0.0038
Brugia malayi latrophilin 2 splice variant baaae 0.0135 0.0111 0.0106
Brugia malayi celfurPC protein 0.3649 0.3969 0.3966
Brugia malayi ADAM-TS Spacer 1 family protein 0.0138 0.0114 0.011
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0131 0.0106 0.2716
Brugia malayi endoprotease bli-4 precursor 0.4524 0.493 0.4928
Onchocerca volvulus 0.0084 0.0054 0.2437
Trypanosoma cruzi ribonucleoside-diphosphate reductase large chain, putative 0.0416 0.0419 1
Toxoplasma gondii subtilisin SUB2 0.0193 0.0175 0.3988
Onchocerca volvulus 0.0144 0.012 0.6581
Plasmodium falciparum subtilisin-like protease 1 0.0193 0.0175 0.3922
Brugia malayi transcriptional regulator, Sir2 family protein 0.0049 0.0017 0.0012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Echinococcus multilocularis integrin alpha ps 0.0743 0.0778 0.1047
Toxoplasma gondii subtilisin SUB10 0.0193 0.0175 0.3988
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0255 0.0242 0.0791
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0007 0.0172
Schistosoma mansoni hypothetical protein 0.0073 0.0042 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0193 0.0175 0.0562
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0049 0.0017 0.0031
Echinococcus multilocularis chromatin regulatory protein sir2 0.0335 0.033 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0193 0.0175 0.0562
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0875 0.0923 0.3079
Trichomonas vaginalis conserved hypothetical protein 0.0875 0.0923 0.3079
Loa Loa (eye worm) TK/EGFR protein kinase 0.0116 0.009 0.0085
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0255 0.0242 0.0238
Mycobacterium ulcerans NAD-dependent deacetylase 0.0049 0.0017 0.0246
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0144 0.012 0.0179
Trichomonas vaginalis ribonucleoside-diphosphate reductase alpha chain, putative 0.0386 0.0386 0.1272

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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