Detailed information for compound 1479004

Basic information

Technical information
  • TDR Targets ID: 1479004
  • Name: 3-(2,3-dihydroindol-1-ylsulfonyl)-N-(4,6-dime thyl-1,3-benzothiazol-2-yl)benzamide
  • MW: 463.572 | Formula: C24H21N3O3S2
  • H donors: 1 H acceptors: 4 LogP: 5.02 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cc(C)c2c(c1)sc(n2)NC(=O)c1cccc(c1)S(=O)(=O)N1CCc2c1cccc2
  • InChi: 1S/C24H21N3O3S2/c1-15-12-16(2)22-21(13-15)31-24(25-22)26-23(28)18-7-5-8-19(14-18)32(29,30)27-11-10-17-6-3-4-9-20(17)27/h3-9,12-14H,10-11H2,1-2H3,(H,25,26,28)
  • InChiKey: WMYGLONHTYVWGM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(4,6-dimethyl-1,3-benzothiazol-2-yl)-3-indolin-1-ylsulfonyl-benzamide
  • N-(4,6-dimethyl-1,3-benzothiazol-2-yl)-3-(1-indolinylsulfonyl)benzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0225 0.1604 0.1604
Brugia malayi Carboxylesterase family protein 0.133 1 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.007 0.0432 0.8904
Onchocerca volvulus 0.002 0.0051 0.0317
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0089 0.0577 0.0577
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0051 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0225 0.1604 0.1604
Loa Loa (eye worm) hypothetical protein 0.0225 0.1604 0.1604
Onchocerca volvulus 0.002 0.0051 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Onchocerca volvulus 0.0225 0.1604 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Onchocerca volvulus 0.0225 0.1604 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Echinococcus granulosus acetylcholinesterase 0.133 1 1
Schistosoma mansoni chromobox protein 0.0079 0.0497 0.0497
Echinococcus granulosus potassium voltage gated channel protein 0.0089 0.0577 0.0577
Toxoplasma gondii cathepsin CPL 0.002 0.0051 1
Brugia malayi cytochrome P450 0.0016 0.0019 0.0019
Loa Loa (eye worm) ctsf protein 0.002 0.0051 0.0051
Toxoplasma gondii exonuclease III APE 0.002 0.0048 0.9203
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0051 0.0032
Echinococcus multilocularis neuropeptide s receptor 0.0529 0.392 0.3909
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0048 0.0631
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Trypanosoma cruzi cruzipain precursor, putative 0.0077 0.0483 1
Echinococcus granulosus cytochrome P450 2K1 0.0016 0.0019 0.0019
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0326 0.0326
Echinococcus granulosus BC026374 protein S09 family 0.0225 0.1604 0.1604
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Onchocerca volvulus Cathepsin F homolog 0.002 0.0051 0.0317
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0048 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Echinococcus multilocularis chromobox protein 1 0.0079 0.0497 0.0479
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0326 0.0326
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0048 0.0048
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0051 0.0051
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0033 0.0033
Schistosoma mansoni gliotactin 0.0225 0.1604 0.1604
Echinococcus multilocularis acetylcholinesterase 0.133 1 1
Schistosoma mansoni hypothetical protein 0.0394 0.2891 0.2891
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Loa Loa (eye worm) hypothetical protein 0.0225 0.1604 0.1604
Loa Loa (eye worm) hypothetical protein 0.0035 0.0161 0.0161
Echinococcus multilocularis carboxylesterase 5A 0.133 1 1
Schistosoma mansoni acetylcholinesterase 0.0225 0.1604 0.1604
Onchocerca volvulus Cathepsin L homolog 0.002 0.0051 0.0317
Loa Loa (eye worm) CYP4Cod1 0.0026 0.0094 0.0094
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0051 0.0051
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0094 0.1627
Loa Loa (eye worm) hypothetical protein 0.0039 0.0191 0.0191
Brugia malayi Carboxylesterase family protein 0.0225 0.1604 0.1604
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0497 0.3098
Onchocerca volvulus Huntingtin homolog 0.0139 0.0952 0.5934
Brugia malayi Heterochromatin protein 1 0.0079 0.0497 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0135 0.0843
Brugia malayi Carboxylesterase family protein 0.0225 0.1604 0.1604
Echinococcus granulosus neuropeptide s receptor 0.0529 0.392 0.392
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0051 0.0032
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0051 0.0032
Onchocerca volvulus 0.002 0.0051 0.0317
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0685
Loa Loa (eye worm) hypothetical protein 0.0225 0.1604 0.1604
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0089 0.0577 0.0577
Trypanosoma cruzi cytochrome P450, putative 0.0026 0.0094 0.1627
Echinococcus multilocularis cysteine protease 0.002 0.0051 0.0032
Loa Loa (eye worm) carboxylesterase 0.133 1 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0048 0.0631
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.0925 0.0925
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0051 0.0032
Echinococcus multilocularis cysteine protease 0.002 0.0051 0.0032
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0033 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Echinococcus multilocularis BC026374 protein (S09 family) 0.0225 0.1604 0.1588
Plasmodium vivax vivapain-2 0.002 0.0051 1
Loa Loa (eye worm) carboxylesterase 0.0225 0.1604 0.1604
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0048 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.0089 0.0577 0.0577
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0051 0.0051
Leishmania major cathepsin L-like protease 0.0077 0.0483 1
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0225 0.1604 0.1604
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0685
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.0259 0.1614
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0685
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0259 0.1614
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0048 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Brugia malayi Cytochrome P450 family protein 0.0016 0.0019 0.0019
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0033 0.0033
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0326 0.0326
Onchocerca volvulus Huntingtin homolog 0.0139 0.0952 0.5934
Echinococcus multilocularis potassium voltage gated channel protein 0.0089 0.0577 0.0559
Entamoeba histolytica cysteine protease, putative 0.002 0.0051 1
Loa Loa (eye worm) hypothetical protein 0.0139 0.0952 0.0952
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0094 0.0094
Trypanosoma brucei cytochrome P450, putative 0.0026 0.0094 0.1627
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0094 0.0094
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0033 0.0033
Echinococcus multilocularis geminin 0.0394 0.2891 0.2877
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0225 0.1604 0.1604
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0026 0.0094 0.0476
Onchocerca volvulus Cathepsin L homolog 0.002 0.0051 0.0317
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0051 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0225 0.1604 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0233 0.0233
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Brugia malayi Cytochrome P450 family protein 0.0059 0.0348 0.0348
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Loa Loa (eye worm) hypothetical protein 0.0056 0.0326 0.0326
Echinococcus multilocularis GPCR, family 2 0.0018 0.0033 0.0014
Loa Loa (eye worm) hypothetical protein 0.002 0.0051 0.0051
Brugia malayi Cytochrome P450 family protein 0.0026 0.0094 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0233 0.1455
Echinococcus multilocularis neuroligin 0.0225 0.1604 0.1588
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.0348 0.0348
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Echinococcus granulosus para nitrobenzyl esterase 0.0225 0.1604 0.1604
Loa Loa (eye worm) hypothetical protein 0.0018 0.0033 0.0033
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Echinococcus granulosus geminin 0.0394 0.2891 0.2891
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0033 0.0033
Mycobacterium leprae Conserved hypothetical protein 0.0016 0.0019 0.5
Brugia malayi chromobox protein homolog 3 0.0044 0.0233 0.0233
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0191 0.0191
Echinococcus granulosus acetylcholinesterase 0.133 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0051 0.0051
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0229 0.1634 0.1634
Loa Loa (eye worm) hypothetical protein 0.133 1 1
Onchocerca volvulus 0.0225 0.1604 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0051 1
Onchocerca volvulus 0.0225 0.1604 1
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0483 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0048 0.5
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0051 1
Mycobacterium ulcerans carboxylesterase, LipT 0.0225 0.1604 1
Echinococcus multilocularis acetylcholinesterase 0.133 1 1
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0048 0.0048
Leishmania major cytochrome p450-like protein 0.0026 0.0094 0.1627
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0051 1
Echinococcus granulosus neuropeptide receptor A26 0.0529 0.392 0.392
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0048 0.0301
Schistosoma mansoni ap endonuclease 0.002 0.0048 0.0048
Echinococcus granulosus GPCR family 2 0.0018 0.0033 0.0033
Loa Loa (eye worm) fibroinase 0.002 0.0051 0.0051
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0225 0.1604 0.1588
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.0925 0.0925
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Schistosoma mansoni chromobox protein 0.0079 0.0497 0.0497
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0483 1
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0051 1
Schistosoma mansoni hypothetical protein 0.0394 0.2891 0.2891
Leishmania major cysteine peptidase A (CPA) 0.002 0.0051 0.0685
Schistosoma mansoni hypothetical protein 0.0018 0.0033 0.0033
Brugia malayi Carboxylesterase family protein 0.0225 0.1604 0.1604
Loa Loa (eye worm) hypothetical protein 0.0225 0.1604 0.1604
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0685
Plasmodium vivax vivapain-2 0.002 0.0051 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0233 0.1455
Echinococcus multilocularis para nitrobenzyl esterase 0.0225 0.1604 0.1588
Onchocerca volvulus 0.002 0.0051 0.0317
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0051 0.0051
Mycobacterium tuberculosis Carboxylesterase LipT 0.0225 0.1604 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0048 0.0301
Leishmania major cathepsin L-like protease 0.002 0.0051 0.0685
Echinococcus multilocularis neuropeptide receptor A26 0.0529 0.392 0.3909
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0051 0.0051
Brugia malayi Cytochrome P450 family protein 0.0026 0.0094 0.0094
Loa Loa (eye worm) cytochrome P450 0.0016 0.0019 0.0019
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0357 0.7297
Brugia malayi hypothetical protein 0.0225 0.1604 0.1604
Loa Loa (eye worm) heterochromatin protein 1 0.0079 0.0497 0.0497
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0233 0.1455
Loa Loa (eye worm) hypothetical protein 0.0089 0.0577 0.0577
Echinococcus granulosus carboxylesterase 5A 0.133 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Schistosoma mansoni voltage-gated potassium channel 0.0089 0.0577 0.0577
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0048 0.5
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0225 0.1604 1
Brugia malayi Carboxylesterase family protein 0.0225 0.1604 0.1604
Loa Loa (eye worm) hypothetical protein 0.0225 0.1604 0.1604
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0051 0.0317
Loa Loa (eye worm) hypothetical protein 0.0139 0.0952 0.0952
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0033 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Schistosoma mansoni neuroligin 3 (S09 family) 0.0225 0.1604 0.1604
Brugia malayi MH2 domain containing protein 0.0135 0.0925 0.0925
Leishmania major cathepsin L-like protease 0.0077 0.0483 1
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0086 0.0547 0.0529
Echinococcus multilocularis chromobox protein 1 0.0079 0.0497 0.0479
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0033 0.0033
Trypanosoma cruzi cysteine peptidase, putative 0.0077 0.0483 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0048 0.0048
Loa Loa (eye worm) acetylcholinesterase 1 0.133 1 1
Echinococcus granulosus neuroligin 0.0225 0.1604 0.1604
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.133 1 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0225 0.1604 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0051 0.0051
Onchocerca volvulus 0.0035 0.0161 0.1002
Onchocerca volvulus 0.002 0.0051 0.0317
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0051 0.0685
Loa Loa (eye worm) hypothetical protein 0.0225 0.1604 0.1604
Leishmania major cathepsin L-like protease 0.0077 0.0483 1
Loa Loa (eye worm) hypothetical protein 0.133 1 1
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Schistosoma mansoni ap endonuclease 0.002 0.0048 0.0048
Echinococcus granulosus chromobox protein 1 0.0079 0.0497 0.0497
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0051 0.0317
Loa Loa (eye worm) cysteine protease 0.002 0.0051 0.0051
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0051 0.0317
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Schistosoma mansoni hypothetical protein 0.0039 0.0191 0.0191
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0048 0.0631
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0048 0.0631
Brugia malayi hypothetical protein 0.0139 0.0952 0.0952
Schistosoma mansoni hypothetical protein 0.0016 0.0019 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0048 0.0259 0.1614
Onchocerca volvulus 0.002 0.0051 0.0317
Schistosoma mansoni BC026374 protein (S09 family) 0.0225 0.1604 0.1604
Brugia malayi Cathepsin L-like precursor 0.002 0.0051 0.0051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Echinococcus granulosus chromobox protein 1 0.0079 0.0497 0.0497
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0135 0.0843
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0048 0.0184
Schistosoma mansoni cytochrome P450 0.0016 0.0019 0.0019
Loa Loa (eye worm) carboxylesterase 0.0225 0.1604 0.1604
Onchocerca volvulus 0.0225 0.1604 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0048 0.9502
Echinococcus granulosus cathepsin l1 0.002 0.0051 0.0051
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0225 0.1604 1
Mycobacterium leprae putative cytochrome p450 0.0016 0.0019 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0077 0.0483 1
Trichomonas vaginalis chromobox protein, putative 0.0079 0.0497 0.3098
Onchocerca volvulus 0.002 0.0051 0.0317

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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