Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.021 | 0.0756 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0719 | 0.0773 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0021 | 0.0397 | 0.1445 |
Echinococcus granulosus | fructose bisphosphate aldolase class I | 0.009 | 0.2726 | 1 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.009 | 0.2726 | 1 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Schistosoma mansoni | pol-related | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0021 | 0.0397 | 0.1445 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0901 | 0.3296 |
Brugia malayi | fructose-bisphosphate aldolase 2 | 0.009 | 0.2726 | 0.3823 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.021 | 0.0756 |
Onchocerca volvulus | 0.0031 | 0.0719 | 0.0436 | |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0021 | 0.0397 | 0.0285 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0283 | 0.9273 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0031 | 0.0719 | 0.2626 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0021 | 0.0397 | 0.0394 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0031 | 0.0719 | 0.0362 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0021 | 0.0397 | 0.1445 |
Plasmodium vivax | fructose 1,6-bisphosphate aldolase, putative | 0.009 | 0.2726 | 1 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0021 | 0.0397 | 0.1445 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.021 | 0.0756 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0304 | 1 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0692 | 0.2526 |
Toxoplasma gondii | aldose reductase, putative | 0.0031 | 0.0719 | 0.2626 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0031 | 0.0719 | 0.2626 |
Onchocerca volvulus | 0.0239 | 0.7777 | 1 | |
Onchocerca volvulus | 0.003 | 0.0692 | 0.0399 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0021 | 0.0397 | 0.1445 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0692 | 0.2526 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0719 | 0.0773 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0285 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0654 | 0.2388 |
Toxoplasma gondii | fructose-bisphosphate aldolase, putative | 0.009 | 0.2726 | 1 |
Brugia malayi | hypothetical protein | 0.0123 | 0.3863 | 0.5549 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1376 | 0.1772 |
Trypanosoma cruzi | aldo-keto reductase | 0.0031 | 0.0719 | 0.2626 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0719 | 0.2626 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0719 | 0.0773 |
Brugia malayi | SWIRM domain containing protein | 0.0021 | 0.0397 | 0.0285 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0692 | 0.2526 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.021 | 0.0756 |
Brugia malayi | Pre-SET motif family protein | 0.021 | 0.6793 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.021 | 0.0756 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0692 | 0.2526 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0901 | 0.105 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0836 | 0.3057 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0031 | 0.0719 | 1 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.009 | 0.2726 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Schistosoma mansoni | amine oxidase | 0.0021 | 0.0397 | 0.1445 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0719 | 0.0773 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0021 | 0.0397 | 0.1445 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0021 | 0.0397 | 0.1445 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0285 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Onchocerca volvulus | 0.0031 | 0.0719 | 0.0436 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0719 | 0.0773 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0285 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Mycobacterium ulcerans | dehydrogenase | 0.0021 | 0.0397 | 0.0394 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0021 | 0.0397 | 0.1445 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0719 | 0.0773 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0719 | 0.2626 |
Mycobacterium ulcerans | oxidoreductase | 0.0031 | 0.0719 | 0.0715 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0719 | 0.2626 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0901 | 0.3296 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0692 | 0.2526 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0285 |
Echinococcus multilocularis | fructose 1,6 bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Onchocerca volvulus | 0.0031 | 0.0719 | 0.0436 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0719 | 1 |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0719 | 1 |
Brugia malayi | fructose-bisphosphate aldolase 1 | 0.009 | 0.2726 | 0.3823 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3863 | 0.5549 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0397 | 0.1445 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.021 | 0.0756 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0719 | 0.0773 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.021 | 0.0756 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0719 | 0.0773 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 2 | 0.009 | 0.2726 | 0.3823 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0692 | 0.0732 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.009 | 0.2726 | 1 |
Echinococcus multilocularis | 0.0021 | 0.0397 | 0.1445 | |
Brugia malayi | hypothetical protein | 0.0021 | 0.0397 | 0.0285 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0836 | 0.0952 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0022 | 0.0415 | 0.0548 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.3863 | 0.4696 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1376 | 0.1772 |
Onchocerca volvulus | 0.0031 | 0.0719 | 0.0436 | |
Leishmania major | fructose-1,6-bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0692 | 0.0732 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.021 | 0.0756 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0719 | 0.2626 |
Plasmodium falciparum | fructose-bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 0.0719 | 0.7967 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | fructose 16 bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0021 | 0.0397 | 0.1445 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.021 | 0.6793 | 1 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0021 | 0.0397 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | aldehyde reductase | 0.0022 | 0.0415 | 0.151 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0021 | 0.0397 | 0.1445 |
Leishmania major | aldo-keto reductase-like protein | 0.0031 | 0.0719 | 0.2626 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0901 | 0.3296 |
Leishmania major | prostaglandin f synthase, putative | 0.0031 | 0.0719 | 0.2626 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1376 | 0.1772 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0692 | 0.2526 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0021 | 0.0397 | 0.1445 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0901 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0031 | 0.0719 | 0.2626 |
Loa Loa (eye worm) | fructose-bisphosphate aldolase 1 | 0.009 | 0.2726 | 0.3823 |
Echinococcus granulosus | hypothetical protein | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0692 | 0.2526 |
Onchocerca volvulus | 0.0031 | 0.0719 | 0.0436 | |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0719 | 0.2626 |
Mycobacterium ulcerans | oxidoreductase | 0.0021 | 0.0397 | 0.0394 |
Onchocerca volvulus | 0.0031 | 0.0719 | 0.0436 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0692 | 0.2526 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0901 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0901 | 0.3296 |
Schistosoma mansoni | amine oxidase | 0.0021 | 0.0397 | 0.1445 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.021 | 0.0756 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0719 | 0.0773 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0031 | 0.0719 | 0.2626 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0719 | 0.2626 |
Trypanosoma brucei | fructose-bisphosphate aldolase, glycosomal, putative | 0.009 | 0.2726 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0021 | 0.0397 | 0.1445 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0836 | 0.0952 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0021 | 0.0397 | 0.1445 |
Toxoplasma gondii | fructose-1,6-bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0123 | 0.3863 | 0.4696 |
Mycobacterium ulcerans | monoamine oxidase | 0.0021 | 0.0397 | 0.0394 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0397 | 0.1445 |
Trichomonas vaginalis | set domain proteins, putative | 0.0239 | 0.7777 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0719 | 0.0773 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0719 | 0.2626 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0285 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Trypanosoma cruzi | fructose-bisphosphate aldolase, glycosomal, putative | 0.009 | 0.2726 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.021 | 0.0756 |
Schistosoma mansoni | fructose 16-bisphosphate aldolase | 0.009 | 0.2726 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0692 | 0.2526 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1376 | 0.1772 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0719 | 0.2626 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0021 | 0.0397 | 0.1445 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0719 | 0.2626 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 0.0719 | 0.7967 |
Echinococcus multilocularis | aldehyde reductase | 0.0022 | 0.0415 | 0.151 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0719 | 0.2626 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0021 | 0.0397 | 0.1445 |
Echinococcus multilocularis | fructose bisphosphate aldolase class I | 0.009 | 0.2726 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.3863 | 0.5549 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0021 | 0.0397 | 0.1445 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0397 | 0.0285 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 0.0719 | 0.7967 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0901 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0901 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.