Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0024 | 0.0193 | 0.0197 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0024 | 0.0193 | 0.0197 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0019 | 0.0097 | 0.0411 |
Brugia malayi | MH2 domain containing protein | 0.0483 | 0.8389 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0361 | 0.6205 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0037 | 0.0417 | 0.0426 |
Schistosoma mansoni | nuclear hormone receptor | 0.0024 | 0.0193 | 0.0195 |
Schistosoma mansoni | tar DNA-binding protein | 0.0161 | 0.2636 | 0.3087 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 0.0773 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0056 | 0.0773 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.002 | 0.0122 | 0.0129 |
Schistosoma mansoni | thyroid hormone receptor | 0.0323 | 0.5521 | 0.6503 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0024 | 0.0193 | 0.0195 |
Schistosoma mansoni | Smad4 | 0.0033 | 0.0353 | 0.0385 |
Brugia malayi | AMP-binding enzyme family protein | 0.0019 | 0.0097 | 0.0083 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0056 | 0.0773 | 0.1247 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0056 | 0.0773 | 0.0816 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0097 | 0.01 |
Trichomonas vaginalis | esterase, putative | 0.0056 | 0.0773 | 0.5 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0056 | 0.0773 | 0.1247 |
Brugia malayi | AMP-binding enzyme family protein | 0.0019 | 0.0097 | 0.0083 |
Loa Loa (eye worm) | RNA binding protein | 0.0161 | 0.2636 | 0.3131 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0019 | 0.0097 | 0.0411 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.002 | 0.0122 | 0.0112 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.0773 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0019 | 0.0097 | 0.0157 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0033 | 0.0353 | 0.0356 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0024 | 0.0193 | 0.0197 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0056 | 0.0773 | 0.372 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 0.222 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0024 | 0.0193 | 0.0166 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0037 | 0.0417 | 0.0465 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0161 | 0.2636 | 0.3131 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0024 | 0.0193 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0773 | 0.0907 |
Brugia malayi | intermediate filament protein | 0.002 | 0.0122 | 0.0112 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0055 | 0.0738 | 0.0777 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0084 | 0.1267 | 0.2042 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.2056 | 0.2439 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0488 | 0.8475 | 0.9248 |
Echinococcus granulosus | lamin | 0.002 | 0.0122 | 0.0102 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0056 | 0.0773 | 0.1247 |
Schistosoma mansoni | thyroid hormone receptor | 0.0323 | 0.5521 | 0.6503 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0488 | 0.8475 | 0.8471 |
Onchocerca volvulus | 0.0056 | 0.0773 | 0.3749 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0161 | 0.2636 | 0.3087 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0323 | 0.5521 | 0.5509 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0299 | 0.5093 | 0.5546 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0773 | 0.0907 |
Echinococcus granulosus | GPCR family 2 | 0.0037 | 0.0417 | 0.0426 |
Brugia malayi | TAR-binding protein | 0.0161 | 0.2636 | 0.3119 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0122 | 0.0129 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0056 | 0.0773 | 0.0747 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0024 | 0.0193 | 0.0197 |
Schistosoma mansoni | lamin | 0.002 | 0.0122 | 0.0111 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0115 | 0.1824 | 0.2162 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0056 | 0.0773 | 0.5 |
Loa Loa (eye worm) | beta-lactamase | 0.0056 | 0.0773 | 0.0907 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0128 | 0.2056 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0738 | 0.084 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0024 | 0.0193 | 0.0181 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0019 | 0.0097 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0024 | 0.0193 | 0.0181 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0299 | 0.5093 | 0.508 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0056 | 0.0773 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0033 | 0.0353 | 0.0405 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0024 | 0.0193 | 0.0166 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0024 | 0.0193 | 0.0831 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0084 | 0.1267 | 0.5971 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0417 | 0.046 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0483 | 0.8389 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0024 | 0.0193 | 0.0197 |
Echinococcus granulosus | Smad4 | 0.0033 | 0.0353 | 0.0356 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0024 | 0.0193 | 0.0181 |
Brugia malayi | hypothetical protein | 0.0126 | 0.2016 | 0.2378 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0024 | 0.0193 | 0.0181 |
Mycobacterium ulcerans | hypothetical protein | 0.0019 | 0.0097 | 0.0411 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0353 | 0.0385 |
Brugia malayi | beta-lactamase | 0.0056 | 0.0773 | 0.0891 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0019 | 0.0097 | 0.0411 |
Loa Loa (eye worm) | Smad1 | 0.0033 | 0.0353 | 0.0405 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0024 | 0.0193 | 0.0166 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0056 | 0.0773 | 0.5 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0353 | 0.0385 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.009 | 0.0075 |
Mycobacterium ulcerans | beta-lactamase | 0.0056 | 0.0773 | 0.372 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0024 | 0.0193 | 0.0831 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0015 | 0.0028 | 0.0017 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0161 | 0.2636 | 0.3119 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0019 | 0.0097 | 0.0411 |
Echinococcus granulosus | tar DNA binding protein | 0.0161 | 0.2636 | 0.2855 |
Mycobacterium leprae | Probable lipase LipE | 0.0056 | 0.0773 | 0.3451 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0055 | 0.0738 | 0.0712 |
Toxoplasma gondii | ABC1 family protein | 0.0056 | 0.0773 | 0.1457 |
Onchocerca volvulus | 0.0056 | 0.0773 | 0.3749 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0056 | 0.0773 | 0.1247 |
Brugia malayi | MH2 domain containing protein | 0.0033 | 0.0353 | 0.0389 |
Echinococcus multilocularis | tumor protein p63 | 0.0527 | 0.9161 | 0.9159 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0024 | 0.0193 | 0.0195 |
Onchocerca volvulus | 0.0126 | 0.2016 | 1 | |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0024 | 0.0193 | 0.0181 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0417 | 0.046 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0024 | 0.0193 | 0.0195 |
Mycobacterium tuberculosis | Conserved protein | 0.0056 | 0.0773 | 0.1247 |
Mycobacterium ulcerans | hypothetical protein | 0.0056 | 0.0773 | 0.372 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0773 | 0.0907 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0014 | 0.0014 | 0.0022 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0056 | 0.0773 | 0.0882 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0056 | 0.0773 | 0.372 |
Mycobacterium ulcerans | lipase LipD | 0.0056 | 0.0773 | 0.372 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0033 | 0.0353 | 0.0326 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0353 | 0.0385 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0097 | 0.01 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0044 | 0.0555 | 0.2335 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0128 | 0.2056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0037 | 0.0417 | 0.0482 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0128 | 0.2056 | 0.2401 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0033 | 0.0353 | 0.0326 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0024 | 0.0193 | 0.0197 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0024 | 0.0193 | 0.0215 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0488 | 0.8475 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0483 | 0.8389 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0037 | 0.0417 | 0.0465 |
Mycobacterium tuberculosis | Conserved protein | 0.0056 | 0.0773 | 0.1247 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0024 | 0.0193 | 0.0197 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0056 | 0.0773 | 0.1247 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.009 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.0097 | 0.0411 |
Onchocerca volvulus | 0.0077 | 0.1141 | 0.5597 | |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0028 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0115 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0773 | 0.0907 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Onchocerca volvulus | 0.0024 | 0.0193 | 0.0831 | |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0044 | 0.0555 | 0.265 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0044 | 0.0555 | 0.265 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0024 | 0.0193 | 0.0197 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0097 | 0.0157 |
Loa Loa (eye worm) | nuclear factor I | 0.0018 | 0.009 | 0.0092 |
Schistosoma mansoni | smad | 0.0033 | 0.0353 | 0.0385 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0033 | 0.0353 | 0.0356 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0056 | 0.0773 | 0.0907 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0738 | 0.0849 |
Schistosoma mansoni | tar DNA-binding protein | 0.0161 | 0.2636 | 0.3087 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0015 | 0.0028 | 0.0017 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0024 | 0.0193 | 0.0197 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0024 | 0.0193 | 0.0195 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0024 | 0.0193 | 0.0215 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0024 | 0.0193 | 0.0197 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0024 | 0.0193 | 0.0166 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0024 | 0.0193 | 0.0197 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0024 | 0.0193 | 0.0166 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0084 | 0.1267 | 0.1356 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0128 | 0.2056 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0019 | 0.0097 | 0.0411 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0084 | 0.1267 | 0.1242 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1141 | 0.1346 |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0353 | 0.0389 |
Entamoeba histolytica | hypothetical protein | 0.0055 | 0.0738 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0037 | 0.0417 | 0.0426 |
Echinococcus granulosus | FTZ F1 alpha | 0.0024 | 0.0193 | 0.0181 |
Echinococcus multilocularis | Smad4 | 0.0033 | 0.0353 | 0.0326 |
Schistosoma mansoni | lamin | 0.002 | 0.0122 | 0.0111 |
Loa Loa (eye worm) | TAR-binding protein | 0.0161 | 0.2636 | 0.3131 |
Onchocerca volvulus | 0.002 | 0.0122 | 0.047 | |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0353 | 0.0389 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0024 | 0.0193 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0773 | 0.0907 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0024 | 0.0193 | 0.0195 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0056 | 0.0773 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1173 | 0.1384 |
Brugia malayi | RNA binding protein | 0.0161 | 0.2636 | 0.3119 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0024 | 0.0193 | 0.0197 |
Schistosoma mansoni | coup transcription factor | 0.0024 | 0.0193 | 0.0195 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0024 | 0.0193 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.1824 | 0.2162 |
Brugia malayi | AMP-binding enzyme family protein | 0.0019 | 0.0097 | 0.0083 |
Schistosoma mansoni | intermediate filament proteins | 0.002 | 0.0122 | 0.0111 |
Brugia malayi | MH2 domain containing protein | 0.0033 | 0.0353 | 0.0389 |
Echinococcus granulosus | lamin dm0 | 0.002 | 0.0122 | 0.0102 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0037 | 0.0417 | 0.039 |
Echinococcus granulosus | smad | 0.0033 | 0.0353 | 0.0356 |
Mycobacterium tuberculosis | Conserved protein | 0.0056 | 0.0773 | 0.1247 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0024 | 0.0193 | 0.0215 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0024 | 0.0193 | 0.0215 |
Entamoeba histolytica | hypothetical protein | 0.0055 | 0.0738 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0024 | 0.0193 | 0.0197 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0024 | 0.0193 | 0.0166 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0024 | 0.0193 | 0.0195 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0024 | 0.0193 | 0.0195 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0084 | 0.1267 | 0.2042 |
Brugia malayi | nuclear receptor NHR-88 | 0.0024 | 0.0193 | 0.0197 |
Onchocerca volvulus | 0.0019 | 0.0097 | 0.0348 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0056 | 0.0773 | 0.372 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0024 | 0.0193 | 0.0215 |
Brugia malayi | Probable ClpP-like protease | 0.0128 | 0.2056 | 0.2426 |
Onchocerca volvulus | 0.0056 | 0.0773 | 0.3749 | |
Entamoeba histolytica | hypothetical protein | 0.0055 | 0.0738 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0037 | 0.0417 | 0.039 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.002 | 0.0122 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.2016 | 0.2391 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0128 | 0.2056 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0033 | 0.0353 | 0.0405 |
Echinococcus multilocularis | GPCR, family 2 | 0.0037 | 0.0417 | 0.039 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0024 | 0.0193 | 0.0195 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0056 | 0.0773 | 0.5 |
Echinococcus granulosus | tumor protein p63 | 0.0527 | 0.9161 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0056 | 0.0773 | 0.0882 |
Brugia malayi | ecdysteroid receptor | 0.0024 | 0.0193 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0773 | 0.0907 |
Entamoeba histolytica | hypothetical protein | 0.0055 | 0.0738 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.002 | 0.0122 | 0.0102 |
Mycobacterium leprae | conserved hypothetical protein | 0.0056 | 0.0773 | 0.3451 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0024 | 0.0193 | 0.0215 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 0.0773 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0024 | 0.0193 | 0.0181 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0033 | 0.0353 | 0.0385 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0056 | 0.0773 | 0.0891 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0077 | 0.1141 | 0.1317 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0056 | 0.0773 | 0.1247 |
Echinococcus multilocularis | musashi | 0.002 | 0.0122 | 0.0094 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0024 | 0.0193 | 0.0197 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0024 | 0.0193 | 0.0197 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0024 | 0.0193 | 0.0195 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0056 | 0.0773 | 0.1247 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0018 | 0.009 | 0.0075 |
Echinococcus multilocularis | tar DNA binding protein | 0.0161 | 0.2636 | 0.2615 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0417 | 0.0482 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0024 | 0.0193 | 0.0181 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0055 | 0.0738 | 0.084 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0417 | 0.046 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0024 | 0.0193 | 0.0197 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0417 | 0.046 |
Brugia malayi | beta-lactamase family protein | 0.0056 | 0.0773 | 0.0891 |
Schistosoma mansoni | hypothetical protein | 0.0079 | 0.1173 | 0.1355 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0024 | 0.0193 | 0.0181 |
Schistosoma mansoni | hypothetical protein | 0.0299 | 0.5093 | 0.5997 |
Brugia malayi | steroid hormone receptor | 0.0024 | 0.0193 | 0.0197 |
Echinococcus multilocularis | lamin dm0 | 0.002 | 0.0122 | 0.0094 |
Onchocerca volvulus | 0.002 | 0.0122 | 0.047 | |
Brugia malayi | nuclear hormone receptor | 0.0024 | 0.0193 | 0.0197 |
Brugia malayi | beta-lactamase family protein | 0.0056 | 0.0773 | 0.0891 |
Schistosoma mansoni | tar DNA-binding protein | 0.0161 | 0.2636 | 0.3087 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0079 | 0.1173 | 0.1369 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0115 | 0.1824 | 0.2148 |
Echinococcus multilocularis | smad | 0.0033 | 0.0353 | 0.0326 |
Schistosoma mansoni | tar DNA-binding protein | 0.0161 | 0.2636 | 0.3087 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0193 | 0.0215 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0024 | 0.0193 | 0.0215 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0128 | 0.2056 | 0.2034 |
Brugia malayi | Smad1 | 0.0033 | 0.0353 | 0.0389 |
Echinococcus multilocularis | lamin | 0.002 | 0.0122 | 0.0094 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0024 | 0.0193 | 0.0831 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0115 | 0.1824 | 0.2148 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0097 | 0.01 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
LC99 (ADMET) | = 155 uM | In vitro cytotoxicity (LC99) of the compound was measured against B16 Melanoma cells | ChEMBL. | 7629806 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.