Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.0189 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Echinococcus multilocularis | geminin | 0.0205 | 0.1817 | 0.1817 |
Brugia malayi | Animal haem peroxidase family protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.0189 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | fibropellin Ia | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | septate junction protein | 0.0301 | 0.2899 | 0.2899 |
Onchocerca volvulus | Putative cubilin | 0.0301 | 0.2899 | 0.2779 |
Brugia malayi | hypothetical protein | 0.0286 | 0.2729 | 0.2729 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Echinococcus granulosus | neural cadherin | 0.0301 | 0.2899 | 0.2899 |
Onchocerca volvulus | 0.0931 | 1 | 1 | |
Schistosoma mansoni | slit | 0.0301 | 0.2899 | 0.2899 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Onchocerca volvulus | Peroxidasin homolog | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | Notch2 | 0.0301 | 0.2899 | 0.2763 |
Brugia malayi | Muscle positioning protein 4 | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Animal haem peroxidase family protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Echinococcus granulosus | protein jagged 2 | 0.0301 | 0.2899 | 0.2899 |
Echinococcus multilocularis | protein jagged 2 | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | peroxidasin | 0.0931 | 1 | 1 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0301 | 0.2899 | 0.2779 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | EGF-like domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | notch-like transmembrane receptor | 0.0301 | 0.2899 | 0.2899 |
Onchocerca volvulus | 0.0301 | 0.2899 | 0.2779 | |
Schistosoma mansoni | cell polarity protein | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | notch | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | notch | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | EGF-like domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | notch | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | EGF-like domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Delta serrate ligand family protein | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1817 | 0.1817 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0931 | 1 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0058 | 0.0167 | 0.0167 |
Onchocerca volvulus | 0.0301 | 0.2899 | 0.2779 | |
Echinococcus granulosus | protein jagged 1 | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Schistosoma mansoni | peroxidasin | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Onchocerca volvulus | Slit protein homolog | 0.0301 | 0.2899 | 0.2779 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | notch protein | 0.0301 | 0.2899 | 0.2763 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | geminin | 0.0205 | 0.1817 | 0.1817 |
Schistosoma mansoni | notch | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | EGF-like domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0286 | 0.2729 | 0.2729 |
Brugia malayi | Cadherin domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Animal haem peroxidase family protein | 0.0931 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0286 | 0.2729 | 0.2589 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0301 | 0.2899 | 0.2899 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | protein jagged 1 | 0.0301 | 0.2899 | 0.2899 |
Onchocerca volvulus | Dual oxidase homolog | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Echinococcus multilocularis | fibropellin Ia | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | slit 2 protein | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0058 | 0.0167 | 0.0167 |
Schistosoma mansoni | notch | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Blistered cuticle protein 3 | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Onchocerca volvulus | 0.0301 | 0.2899 | 0.2779 | |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Brugia malayi | Animal haem peroxidase family protein | 0.0931 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0931 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0301 | 0.2899 | 0.2899 |
Echinococcus multilocularis | protein jagged 1 | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | delta-like protein 1 | 0.0301 | 0.2899 | 0.2899 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0301 | 0.2899 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0931 | 1 | 1 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0301 | 0.2899 | 0.2779 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2899 | 0.2899 |
Onchocerca volvulus | Peroxidase homolog | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0931 | 1 | 1 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Echinococcus multilocularis | neural cadherin | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | notch | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.0167 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Onchocerca volvulus | 0.0931 | 1 | 1 | |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | protein jagged 2 | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Echinococcus multilocularis | notch | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0931 | 1 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0286 | 0.2729 | 0.2729 |
Echinococcus multilocularis | protein jagged 1 | 0.0301 | 0.2899 | 0.2899 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Peroxidasin | 0.0931 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0931 | 1 | 1 |
Giardia lamblia | High cysteine protein | 0.0301 | 0.2899 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.1817 | 0.1817 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0 | 0.5 |
Onchocerca volvulus | 0.0301 | 0.2899 | 0.2779 | |
Brugia malayi | Cadherin domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | Animal haem peroxidase family protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0931 | 1 | 1 |
Onchocerca volvulus | 0.0301 | 0.2899 | 0.2779 | |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0 | 0.5 |
Brugia malayi | EGF-like domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Echinococcus multilocularis | slit 2 protein | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | notch | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0931 | 1 | 1 |
Echinococcus multilocularis | peroxidasin | 0.0931 | 1 | 1 |
Onchocerca volvulus | 0.0931 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2899 | 0.2899 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0931 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0301 | 0.2899 | 0.2899 |
Brugia malayi | EGF-like domain containing protein | 0.0301 | 0.2899 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.2899 | 0.2763 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.