Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.1768 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Loa Loa (eye worm) | hypothetical protein | 0.1768 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1768 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Loa Loa (eye worm) | carboxylesterase | 0.0299 | 0.1406 | 0.1406 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Brugia malayi | Carboxylesterase family protein | 0.1768 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0299 | 0.1406 | 0.1406 |
Brugia malayi | Carboxylesterase family protein | 0.0299 | 0.1406 | 0.1406 |
Echinococcus granulosus | carboxylesterase 5A | 0.1768 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1768 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1768 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1768 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1768 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.1768 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1768 | 1 | 1 |
Onchocerca volvulus | 0.0299 | 0.1406 | 0.5 | |
Onchocerca volvulus | 0.0299 | 0.1406 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0299 | 0.1406 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0299 | 0.1406 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0299 | 0.1406 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0299 | 0.1406 | 0.5 |
Onchocerca volvulus | 0.0299 | 0.1406 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.1768 | 1 | 1 |
Onchocerca volvulus | 0.0299 | 0.1406 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0299 | 0.1406 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0299 | 0.1406 | 0.1406 |
Brugia malayi | Carboxylesterase family protein | 0.0299 | 0.1406 | 0.1406 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0299 | 0.1406 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Onchocerca volvulus | 0.0299 | 0.1406 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.1406 | 0.1406 |
Brugia malayi | Carboxylesterase family protein | 0.0299 | 0.1406 | 0.1406 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.