Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | hexokinase | 0.1465 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0919 | 0.6156 | 0.6156 |
Plasmodium falciparum | hexokinase | 0.1465 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1465 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.1465 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.1465 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.1465 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.053 | 0.053 |
Schistosoma mansoni | hexokinase | 0.1465 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.053 | 0.053 |
Trypanosoma cruzi | hexokinase, putative | 0.1465 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.1465 | 1 | 0.5 |
Onchocerca volvulus | Hexokinase homolog | 0.0919 | 0.6156 | 0.5941 |
Echinococcus multilocularis | hexokinase | 0.1465 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.1465 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.1465 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.1465 | 1 | 0.5 |
Brugia malayi | hexokinase type II | 0.0466 | 0.2964 | 0.2964 |
Loa Loa (eye worm) | hexokinase | 0.1465 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.012 | 0.053 | 0.053 |
Loa Loa (eye worm) | hypothetical protein | 0.0999 | 0.672 | 0.672 |
Echinococcus granulosus | hexokinase | 0.1465 | 1 | 1 |
Plasmodium vivax | hexokinase, putative | 0.1465 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0919 | 0.6156 | 0.6156 |
Trypanosoma brucei | hexokinase | 0.1465 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.1465 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0466 | 0.2964 | 0.2964 |
Loa Loa (eye worm) | hexokinase type II | 0.1465 | 1 | 1 |
Onchocerca volvulus | 0.1465 | 1 | 1 | |
Entamoeba histolytica | hexokinase 2 | 0.1465 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.1465 | 1 | 1 |
Trypanosoma brucei | hexokinase, putative | 0.1465 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.1465 | 1 | 1 |
Echinococcus granulosus | hexokinase type 2 | 0.1465 | 1 | 1 |
Onchocerca volvulus | 0.1465 | 1 | 1 | |
Brugia malayi | Hexokinase family protein | 0.0453 | 0.2876 | 0.2876 |
Onchocerca volvulus | 0.1465 | 1 | 1 | |
Onchocerca volvulus | 0.0919 | 0.6156 | 0.5941 | |
Loa Loa (eye worm) | hexokinase | 0.1465 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0466 | 0.2964 | 0.2964 |
Loa Loa (eye worm) | hexokinase | 0.0453 | 0.2876 | 0.2876 |
Echinococcus multilocularis | hexokinase type 2 | 0.1465 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.