TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 389.538 | Formula: C20H35N7O
H donors: 3 H acceptors: 4 LogP: 3.89 Rotable bonds: 16
Rule of 5 violations (Lipinski): 1
SMILES: CCCCCCCCNC(=O)Cn1nnc(c1)CCCCCc1c[nH]c(n1)N
InChi: 1S/C20H35N7O/c1-2-3-4-5-6-10-13-22-19(28)16-27-15-18(25-26-27)12-9-7-8-11-17-14-23-20(21)24-17/h14-15H,2-13,16H2,1H3,(H,22,28)(H3,21,23,24)
InChiKey: YCDUUOAGYJASNS-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Plasmodium vivax	tubulin beta chain, putative	0.008	0.0891	1
Plasmodium falciparum	tubulin beta chain	0.008	0.0891	1
Schistosoma mansoni	alpha tubulin	0.0049	0.0422	0.0419
Leishmania major	beta tubulin	0.008	0.0891	1
Leishmania major	beta tubulin	0.008	0.0891	1
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0048	0.0411	0.0817
Echinococcus granulosus	smad	0.0024	0.0038	0.0038
Toxoplasma gondii	alpha tubulin TUBA1	0.0049	0.0422	0.4716
Onchocerca volvulus		0.0048	0.0405	1
Loa Loa (eye worm)	tubulin alpha 2	0.0028	0.0098	0.0197
Toxoplasma gondii	tubulin/FtsZ family, GTPase domain-containing protein	0.0049	0.0422	0.4716
Loa Loa (eye worm)	MH2 domain-containing protein	0.035	0.4991	1
Loa Loa (eye worm)	tubulin beta-2A chain	0.008	0.0891	0.1785
Echinococcus granulosus	Tubulin alpha 1 chain	0.0049	0.0422	0.0422
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0049	0.0422	0.0422
Schistosoma mansoni	tar DNA-binding protein	0.0252	0.3503	0.35
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0024	0.0038	0.0034
Echinococcus multilocularis	tubulin epsilon chain	0.0049	0.0422	0.0422
Loa Loa (eye worm)	BEN-1 protein	0.008	0.0891	0.1785
Echinococcus multilocularis	multidrug resistance protein 1	0.0022	0.0004	0.0004
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0049	0.0422	0.4716
Echinococcus multilocularis	tubulin alpha chain	0.0049	0.0422	0.0422
Mycobacterium tuberculosis	Probable transmembrane multidrug efflux pump	0.0022	0.0004	0.5
Trichomonas vaginalis	tubulin beta chain, putative	0.0049	0.0422	0.4716
Brugia malayi	MH2 domain containing protein	0.0024	0.0038	0.0069
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0022	0.0004	0.0004
Brugia malayi	beta-tubulin, identical	0.008	0.0891	0.1779
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0022	0.0004	0.0004
Schistosoma mansoni	microtubule-associated protein tau	0.068	1	1
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Echinococcus multilocularis	tubulin alpha 3 chain	0.0049	0.0422	0.0422
Echinococcus granulosus	tubulin alpha	0.0049	0.0422	0.0422
Trichomonas vaginalis	tubulin beta chain, putative	0.0049	0.0422	0.4716
Schistosoma mansoni	tubulin subunit beta	0.008	0.0891	0.0888
Echinococcus granulosus	tumor protein p63	0.0328	0.4658	0.4658
Toxoplasma gondii	beta tubulin	0.008	0.0891	1
Echinococcus granulosus	Tubulin beta 2C chain	0.008	0.0891	0.0891
Schistosoma mansoni	tubulin subunit beta	0.008	0.0891	0.0888
Trichomonas vaginalis	tubulin beta chain, putative	0.0049	0.0422	0.4716
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Loa Loa (eye worm)	beta-tubulin	0.008	0.0891	0.1785
Brugia malayi	alpha-tubulin	0.0049	0.0422	0.0839
Schistosoma mansoni	tar DNA-binding protein	0.0252	0.3503	0.35
Schistosoma mansoni	tubulin subunit beta	0.008	0.0891	0.0888
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0049	0.0422	0.0422
Schistosoma mansoni	smad1 5 8 and	0.0024	0.0038	0.0034
Trichomonas vaginalis	tubulin, putative	0.0028	0.0098	0.1065
Echinococcus multilocularis	multidrug resistance protein 1	0.0022	0.0004	0.0004
Echinococcus granulosus	tubulin beta 1 chain	0.008	0.0891	0.0891
Onchocerca volvulus		0.0028	0.0098	0.2354
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0048	0.0411	0.0823
Leishmania major	epsilon tubulin, putative	0.0049	0.0422	0.4716
Leishmania major	beta tubulin	0.008	0.0891	1
Brugia malayi	MH2 domain containing protein	0.035	0.4991	1
Echinococcus granulosus	multidrug resistance protein 1	0.0022	0.0004	0.0004
Echinococcus granulosus	Tubulin beta 2C chain	0.008	0.0891	0.0891
Echinococcus granulosus	alpha tubulin	0.0049	0.0422	0.0422
Loa Loa (eye worm)	alpha-tubulin	0.0049	0.0422	0.0846
Plasmodium vivax	tubulin gamma chain, putative	0.0049	0.0422	0.4716
Trichomonas vaginalis	tubulin beta chain, putative	0.0049	0.0422	0.4716
Trichomonas vaginalis	tubulin alpha chain, putative	0.008	0.0891	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0178	0.035
Giardia lamblia	Beta tubulin	0.008	0.0891	1
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0178	0.0357
Schistosoma mansoni	hypothetical protein	0.0033	0.0178	0.0175
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0024	0.0038	0.0038
Schistosoma mansoni	tubulin subunit epsilon	0.0049	0.0422	0.0419
Echinococcus granulosus	tubulin alpha 1C chain	0.0049	0.0422	0.0422
Loa Loa (eye worm)	alpha-tubulin	0.0049	0.0422	0.0846
Echinococcus multilocularis	tar DNA binding protein	0.0252	0.3503	0.3503
Schistosoma mansoni	tar DNA-binding protein	0.0252	0.3503	0.35
Brugia malayi	Tubulin alpha chain	0.0049	0.0422	0.0839
Leishmania major	gamma-tubulin	0.0049	0.0422	0.4716
Echinococcus granulosus	tubulin alpha chain	0.0049	0.0422	0.0422
Trichomonas vaginalis	tubulin epsilon chain, putative	0.008	0.0891	1
Trichomonas vaginalis	tubulin alpha chain, putative	0.0028	0.0098	0.1065
Echinococcus multilocularis	tubulin alpha 1C chain	0.0049	0.0422	0.0422
Loa Loa (eye worm)	Smad1	0.0024	0.0038	0.0076
Schistosoma mansoni	tar DNA-binding protein	0.0252	0.3503	0.35
Schistosoma mansoni	tubulin subunit gamma	0.0049	0.0422	0.0419
Echinococcus granulosus	Smad4	0.0024	0.0038	0.0038
Leishmania major	beta tubulin	0.008	0.0891	1
Trichomonas vaginalis	tubulin gamma chain, putative	0.0049	0.0422	0.4716
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0004	0.0007
Loa Loa (eye worm)	BEN-1 protein	0.008	0.0891	0.1785
Leishmania major	beta tubulin	0.008	0.0891	1
Schistosoma mansoni	tubulin subunit beta	0.008	0.0891	0.0888
Plasmodium vivax	tubulin alpha chain, putative	0.0049	0.0422	0.4716
Trichomonas vaginalis	tubulin beta chain, putative	0.0049	0.0422	0.4716
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Trypanosoma brucei	epsilon tubulin	0.0049	0.0422	0.4087
Loa Loa (eye worm)	ATP-binding cassette sub-family B member 2	0.0022	0.0004	0.0007
Trichomonas vaginalis	tubulin gamma chain, putative	0.0049	0.0422	0.4716
Entamoeba histolytica	tubulin family protein	0.008	0.0891	1
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus granulosus	tubulin alpha chain	0.0049	0.0422	0.0422
Schistosoma mansoni	tubulin subunit beta	0.008	0.0891	0.0888
Trichomonas vaginalis	tubulin beta chain, putative	0.0028	0.0098	0.1065
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0048	0.0411	0.0817
Leishmania major	beta tubulin	0.008	0.0891	1
Trypanosoma brucei	beta tubulin	0.008	0.0891	1
Echinococcus granulosus	mothers against decapentaplegic 5	0.0024	0.0038	0.0038
Echinococcus granulosus	Tubulin alpha 1 chain	0.0049	0.0422	0.0422
Echinococcus multilocularis	tubulin alpha chain	0.0049	0.0422	0.0422
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0024	0.0038	0.0038
Trichomonas vaginalis	tubulin beta chain, putative	0.008	0.0891	1
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Echinococcus multilocularis	Smad4	0.0024	0.0038	0.0038
Brugia malayi	tubulin alpha chain - mouse	0.0049	0.0422	0.0839
Schistosoma mansoni	Smad4	0.0024	0.0038	0.0034
Entamoeba histolytica	tubulin alpha chain, putative	0.0049	0.0422	0.4716
Loa Loa (eye worm)	alpha-tubulin isotype 2	0.0028	0.0098	0.0197
Loa Loa (eye worm)	tubulin beta chain	0.008	0.0891	0.1785
Loa Loa (eye worm)	TAR-binding protein	0.0252	0.3503	0.7018
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0028	0.0098	0.1065
Echinococcus multilocularis	beta tubulin	0.008	0.0891	0.0891
Echinococcus multilocularis	tubulin beta 1 chain	0.008	0.0891	0.0891
Loa Loa (eye worm)	tubulin alpha-2 chain	0.0049	0.0422	0.0846
Echinococcus multilocularis	tubulin gamma 1 chain	0.0049	0.0422	0.0422
Echinococcus multilocularis	tubulin alpha 1C chain	0.0049	0.0422	0.0422
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0024	0.0038	0.0038
Leishmania major	beta tubulin	0.008	0.0891	1
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0411	0.0823
Plasmodium falciparum	tubulin epsilon chain, putative	0.0049	0.0422	0.4716
Brugia malayi	Smad1	0.0024	0.0038	0.0069
Schistosoma mansoni	alpha tubulin	0.0049	0.0422	0.0419
Plasmodium falciparum	tubulin gamma chain	0.0049	0.0422	0.4716
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus multilocularis	tubulin alpha 3 chain	0.0049	0.0422	0.0422
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0422	0.0846
Brugia malayi	tubulin alpha-2 chain	0.0049	0.0422	0.0839
Loa Loa (eye worm)	tubulin alpha chain	0.0049	0.0422	0.0846
Leishmania major	beta tubulin	0.008	0.0891	1
Brugia malayi	RNA recognition motif domain containing protein	0.0252	0.3503	0.7016
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0049	0.0422	0.4716
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus granulosus	tubulin gamma 1 chain	0.0049	0.0422	0.0422
Schistosoma mansoni	tar DNA-binding protein	0.0252	0.3503	0.35
Echinococcus multilocularis	Tubulin beta 2C chain	0.008	0.0891	0.0891
Loa Loa (eye worm)	RNA binding protein	0.0252	0.3503	0.7018
Brugia malayi	Tubulin gamma chain	0.0049	0.0422	0.0839
Echinococcus multilocularis	Tubulin beta 2C chain	0.008	0.0891	0.0891
Echinococcus granulosus	tar DNA binding protein	0.0252	0.3503	0.3503
Echinococcus multilocularis	Tubulin beta 2C chain	0.008	0.0891	0.0891
Trypanosoma brucei	beta tubulin	0.0049	0.0422	0.4087
Schistosoma mansoni	tubulin subunit beta	0.008	0.0891	0.0888
Brugia malayi	RNA binding protein	0.0252	0.3503	0.7016
Echinococcus granulosus	beta tubulin	0.008	0.0891	0.0891
Trichomonas vaginalis	tubulin, putative	0.008	0.0891	1
Trichomonas vaginalis	tubulin gamma chain, putative	0.008	0.0891	1
Chlamydia trachomatis	ABC transporter ATP binding protein/permease	0.0022	0.0004	0.5
Schistosoma mansoni	tubulin subunit alpha	0.0049	0.0422	0.0419
Echinococcus multilocularis	hypothetical protein	0.0049	0.0422	0.0422
Echinococcus granulosus	Tubulin alpha 1 chain	0.0049	0.0422	0.0422
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0252	0.3503	0.7018
Trypanosoma brucei	alpha tubulin	0.0049	0.0422	0.4087
Echinococcus multilocularis	tubulin alpha chain	0.0049	0.0422	0.0422
Echinococcus granulosus	tubulin subunit TubB	0.0049	0.0422	0.0422
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0022	0.0004	0.0004
Brugia malayi	MH1 domain containing protein	0.0024	0.0038	0.0069
Echinococcus multilocularis	Tubulin alpha 1 chain	0.0049	0.0422	0.0422
Trypanosoma brucei	beta tubulin	0.008	0.0891	1
Loa Loa (eye worm)	MH1 domain-containing protein	0.0024	0.0038	0.0076
Trichomonas vaginalis	tubulin epsilon chain, putative	0.008	0.0891	1
Schistosoma mansoni	smad1 5 8 and	0.0024	0.0038	0.0034
Trichomonas vaginalis	tubulin alpha chain, putative	0.0028	0.0098	0.1065
Plasmodium vivax	tubulin epsilon chain, putative	0.0049	0.0422	0.4716
Trypanosoma brucei	alpha tubulin	0.0049	0.0422	0.4087
Loa Loa (eye worm)	tubulin alpha 2	0.0028	0.0098	0.0197
Schistosoma mansoni	alpha tubulin	0.0049	0.0422	0.0419
Echinococcus granulosus	tubulin epsilon chain	0.0049	0.0422	0.0422
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0049	0.0422	0.4716
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0022	0.0004	0.0004
Echinococcus multilocularis	Tubulin beta 2C chain	0.008	0.0891	0.0891
Giardia lamblia	Beta tubulin	0.008	0.0891	1
Brugia malayi	Tubulin alpha-2 chain	0.0049	0.0422	0.0839
Echinococcus granulosus	tubulin alpha 1C chain	0.0049	0.0422	0.0422
Toxoplasma gondii	beta-1 tubulin, putative	0.008	0.0891	1
Leishmania major	beta tubulin	0.008	0.0891	1
Trypanosoma brucei	epsilon tubulin	0.0049	0.0422	0.4087
Loa Loa (eye worm)	transcription factor SMAD2	0.035	0.4991	1
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Echinococcus multilocularis	tubulin subunit beta	0.008	0.0891	0.0891
Echinococcus multilocularis	beta tubulin	0.008	0.0891	0.0891
Echinococcus granulosus	multidrug resistance protein 1	0.0022	0.0004	0.0004
Loa Loa (eye worm)	multidrug resistance protein 3	0.0022	0.0004	0.0007
Echinococcus granulosus	tubulin alpha 3 chain	0.0049	0.0422	0.0422
Schistosoma mansoni	cellular tumor antigen P53	0.0048	0.0405	0.0402
Toxoplasma gondii	alpha-tubulin I, putative	0.0049	0.0422	0.4716
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0022	0.0004	0.0004
Trichomonas vaginalis	tubulin beta chain, putative	0.0049	0.0422	0.4716
Entamoeba histolytica	tubulin gamma chain	0.0049	0.0422	0.4716
Leishmania major	beta tubulin	0.008	0.0891	1
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus granulosus	tubulin alpha chain	0.0049	0.0422	0.0422
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0405	0.0812
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus granulosus	peroxisome assembly protein 26	0.0049	0.0422	0.0422
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0022	0.0004	0.0004
Echinococcus granulosus	Tubulin beta 2C chain	0.008	0.0891	0.0891
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Plasmodium falciparum	alpha tubulin 1	0.0049	0.0422	0.4716
Trypanosoma brucei	epsilon tubulin	0.0049	0.0422	0.4087
Entamoeba histolytica	tubulin alpha-1 chain	0.0049	0.0422	0.4716
Echinococcus granulosus	Tubulin beta 2C chain	0.008	0.0891	0.0891
Plasmodium vivax	tubulin alpha chain, putative	0.0049	0.0422	0.4716
Brugia malayi	Tubulin beta-1 chain	0.008	0.0891	0.1779
Echinococcus granulosus	tubulin alpha chain	0.0049	0.0422	0.0422
Toxoplasma gondii	beta-tubulin, putative	0.008	0.0891	1
Echinococcus multilocularis	tubulin alpha chain	0.0049	0.0422	0.0422
Echinococcus multilocularis	tubulin alpha	0.0049	0.0422	0.0422
Schistosoma mansoni	tubulin subunit alpha	0.0049	0.0422	0.0419
Loa Loa (eye worm)	tubulin beta-1 chain	0.008	0.0891	0.1785
Echinococcus multilocularis	tubulin, beta 4A class IVa	0.008	0.0891	0.0891
Trichomonas vaginalis	tubulin alpha-1 chain, putative	0.0028	0.0098	0.1065
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus granulosus	tubulin beta 4A class IVa	0.008	0.0891	0.0891
Echinococcus granulosus	ATP binding cassette subfamily B MDR:TAP	0.0022	0.0004	0.0004
Trypanosoma brucei	tubulin gamma chain	0.0049	0.0422	0.4087
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Echinococcus granulosus	tubulin subunit beta	0.008	0.0891	0.0891
Schistosoma mansoni	tubulin subunit alpha	0.0049	0.0422	0.0419
Brugia malayi	MH2 domain containing protein	0.0024	0.0038	0.0069
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0004	0.0007
Trichomonas vaginalis	tubulin alpha chain, putative	0.0049	0.0422	0.4716
Brugia malayi	Tubulin beta chain	0.0028	0.0098	0.0189
Echinococcus multilocularis	smad	0.0024	0.0038	0.0038
Echinococcus multilocularis	tubulin alpha chain	0.0049	0.0422	0.0422
Echinococcus multilocularis	tubulin subunit TubB	0.0049	0.0422	0.0422
Trypanosoma brucei	beta tubulin	0.008	0.0891	1
Echinococcus multilocularis	Tubulin beta 2C chain	0.008	0.0891	0.0891
Echinococcus granulosus	tubulin alpha 3 chain	0.0049	0.0422	0.0422
Brugia malayi	TAR-binding protein	0.0252	0.3503	0.7016
Trypanosoma brucei	beta tubulin	0.008	0.0891	1
Giardia lamblia	Beta tubulin	0.008	0.0891	1
Loa Loa (eye worm)	tubulin alpha chain	0.0049	0.0422	0.0846
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0022	0.0004	0.0004
Echinococcus granulosus	multidrug resistance protein 1	0.0022	0.0004	0.0004
Brugia malayi	Tubulin alpha-2 chain	0.0049	0.0422	0.0839
Loa Loa (eye worm)	tubulin gamma chain	0.0049	0.0422	0.0846
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus multilocularis	microtubule associated protein 2	0.068	1	1
Entamoeba histolytica	tubulin family protein	0.008	0.0891	1
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Echinococcus granulosus	tubulin alpha chain	0.0049	0.0422	0.0422
Trichomonas vaginalis	tubulin alpha chain, putative	0.0028	0.0098	0.1065
Loa Loa (eye worm)	tubulin beta-4 chain	0.008	0.0891	0.1785
Echinococcus multilocularis	peroxisome assembly protein 26	0.0049	0.0422	0.0422
Trypanosoma brucei	alpha tubulin	0.0049	0.0422	0.4087
Trichomonas vaginalis	tubulin, putative	0.0028	0.0098	0.1065
Loa Loa (eye worm)	MH2 domain-containing protein	0.0024	0.0038	0.0076
Echinococcus granulosus	Tubulin beta 2C chain	0.008	0.0891	0.0891
Leishmania major	beta tubulin	0.008	0.0891	1
Echinococcus multilocularis	tumor protein p63	0.0328	0.4658	0.4658
Schistosoma mansoni	smad	0.0024	0.0038	0.0034
Leishmania major	alpha tubulin	0.0049	0.0422	0.4716
Echinococcus multilocularis	ATP binding cassette subfamily B (MDR:TAP)	0.0022	0.0004	0.0004
Brugia malayi	MH1 domain containing protein	0.0024	0.0038	0.0069
Plasmodium falciparum	alpha tubulin 2	0.0049	0.0422	0.4716
Schistosoma mansoni	smad1 5 8 and	0.0024	0.0038	0.0034
Trypanosoma brucei	alpha tubulin	0.0049	0.0422	0.4087
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0098	0.0197
Echinococcus granulosus	beta tubulin	0.008	0.0891	0.0891
Trypanosoma cruzi	beta tubulin, putative	0.008	0.0891	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1617899

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1479815