Detailed information for compound 1479821

Basic information

Technical information
  • TDR Targets ID: 1479821
  • Name: 4-phenyl-5,6-dihydro-4H-pyrrolo[1,2-a][1,4]be nzodiazepine
  • MW: 260.333 | Formula: C18H16N2
  • H donors: 1 H acceptors: 0 LogP: 2.99 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: c1ccc(cc1)C1NCc2c(n3c1ccc3)cccc2
  • InChi: 1S/C18H16N2/c1-2-7-14(8-3-1)18-17-11-6-12-20(17)16-10-5-4-9-15(16)13-19-18/h1-12,18-19H,13H2
  • InChiKey: NUCZYEHNXNPWBA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • A2931/0123353
  • 4H-Benzo[f]pyrrolo[1,2-a][1,4]diazepine, 4-phenyl-5,6-dihydro-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis tubulin beta chain, putative 0.0047 0.4738 0.4738
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Trypanosoma brucei beta tubulin 0.0047 0.4738 0.4738
Schistosoma mansoni alpha tubulin 0.0047 0.4738 0.4738
Echinococcus granulosus tubulin alpha 1C chain 0.0047 0.4738 0.4738
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0042 0.0042
Echinococcus granulosus beta tubulin 0.0076 1 1
Echinococcus multilocularis tubulin alpha 0.0047 0.4738 0.4738
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0042 0.0042
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0042 0.0042
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0042 0.0042
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0042 0.0042
Echinococcus granulosus tubulin alpha chain 0.0047 0.4738 0.4738
Plasmodium falciparum tubulin beta chain 0.0076 1 1
Trichomonas vaginalis tubulin epsilon chain, putative 0.0047 0.4738 0.4738
Plasmodium falciparum alpha tubulin 1 0.0047 0.4738 0.4738
Echinococcus granulosus Tubulin beta 2C chain 0.0076 1 1
Leishmania major beta tubulin 0.0076 1 1
Schistosoma mansoni alpha tubulin 0.0047 0.4738 0.4738
Giardia lamblia Beta tubulin 0.0076 1 1
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0042 0.0042
Brugia malayi multidrug resistance protein 3 0.0021 0.0042 0.0042
Echinococcus granulosus tubulin subunit beta 0.0076 1 1
Loa Loa (eye worm) alpha-tubulin 0.0047 0.4738 0.4738
Loa Loa (eye worm) tubulin beta-1 chain 0.0076 1 1
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Echinococcus multilocularis tubulin alpha chain 0.0047 0.4738 0.4738
Loa Loa (eye worm) hypothetical protein 0.0027 0.1102 0.1102
Echinococcus multilocularis tubulin alpha chain 0.0047 0.4738 0.4738
Echinococcus granulosus tubulin alpha 1C chain 0.0047 0.4738 0.4738
Brugia malayi Tubulin gamma chain 0.0047 0.4738 0.4738
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0042
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Schistosoma mansoni tubulin subunit beta 0.0076 1 1
Brugia malayi Tubulin beta chain 0.0027 0.1102 0.1102
Brugia malayi beta-tubulin, identical 0.0076 1 1
Toxoplasma gondii alpha tubulin TUBA1 0.0047 0.4738 0.4738
Brugia malayi alpha-tubulin 0.0047 0.4738 0.4738
Echinococcus multilocularis Tubulin beta 2C chain 0.0076 1 1
Leishmania major beta tubulin 0.0076 1 1
Loa Loa (eye worm) tubulin alpha 2 0.0027 0.1102 0.1102
Leishmania major beta tubulin 0.0076 1 1
Echinococcus granulosus tubulin alpha 3 chain 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin epsilon chain, putative 0.0076 1 1
Echinococcus granulosus tubulin alpha 0.0047 0.4738 0.4738
Trypanosoma brucei epsilon tubulin 0.0047 0.4738 0.4738
Schistosoma mansoni tubulin subunit alpha 0.0047 0.4738 0.4738
Plasmodium vivax tubulin epsilon chain, putative 0.0047 0.4738 0.4738
Trypanosoma brucei alpha tubulin, putative 0.0027 0.1102 0.1102
Schistosoma mansoni multidrug resistance protein 0.0021 0.0042 0.0042
Schistosoma mansoni tubulin subunit beta 0.0076 1 1
Echinococcus multilocularis tubulin alpha 1C chain 0.0047 0.4738 0.4738
Trypanosoma cruzi tubulin gamma chain 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin beta chain, putative 0.0027 0.1102 0.1102
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis tubulin beta chain, putative 0.0047 0.4738 0.4738
Schistosoma mansoni tubulin subunit beta 0.0076 1 1
Echinococcus multilocularis Tubulin alpha 1 chain 0.0047 0.4738 0.4738
Echinococcus multilocularis Tubulin beta 2C chain 0.0076 1 1
Loa Loa (eye worm) hypothetical protein 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin gamma chain, putative 0.0047 0.4738 0.4738
Echinococcus granulosus beta tubulin 0.0076 1 1
Leishmania major beta tubulin 0.0076 1 1
Trichomonas vaginalis tubulin, putative 0.0076 1 1
Echinococcus multilocularis tubulin subunit beta 0.0076 1 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0042 0.0042
Echinococcus granulosus Tubulin alpha 1 chain 0.0047 0.4738 0.4738
Leishmania major beta tubulin 0.0076 1 1
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Echinococcus multilocularis Tubulin beta 2C chain 0.0076 1 1
Echinococcus multilocularis tubulin epsilon chain 0.0047 0.4738 0.4738
Loa Loa (eye worm) tubulin alpha chain 0.0047 0.4738 0.4738
Trypanosoma brucei alpha tubulin 0.0047 0.4738 0.4738
Schistosoma mansoni tubulin subunit alpha 0.0047 0.4738 0.4738
Giardia lamblia Gamma tubulin 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin, putative 0.0027 0.1102 0.1102
Toxoplasma gondii beta-1 tubulin, putative 0.0076 1 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0047 0.4738 0.4738
Loa Loa (eye worm) tubulin beta-2A chain 0.0076 1 1
Echinococcus multilocularis tubulin alpha chain 0.0047 0.4738 0.4738
Echinococcus multilocularis Tubulin alpha 1 chain 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin gamma chain, putative 0.0076 1 1
Wolbachia endosymbiont of Brugia malayi cell division protein FtsZ 0.002 0 0.5
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0042 0.0042
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0042 1
Trypanosoma cruzi alpha tubulin, putative 0.0047 0.4738 0.4738
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0042 0.0042
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Loa Loa (eye worm) tubulin gamma chain 0.0047 0.4738 0.4738
Brugia malayi tubulin alpha chain - mouse 0.0047 0.4738 0.4738
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0042 0.0042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis tubulin alpha chain, putative 0.0027 0.1102 0.1102
Loa Loa (eye worm) tubulin beta chain 0.0076 1 1
Echinococcus granulosus tubulin beta 4A class IVa 0.0076 1 1
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0047 0.4738 0.4738
Toxoplasma gondii alpha-tubulin I, putative 0.0047 0.4738 0.4738
Onchocerca volvulus 0.0027 0.1102 1
Echinococcus granulosus alpha tubulin 0.0047 0.4738 0.4738
Plasmodium vivax tubulin beta chain, putative 0.0076 1 1
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0042 0.0042
Schistosoma mansoni smdr2 0.0021 0.0042 0.0042
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0042 0.0042
Echinococcus granulosus Tubulin alpha 1 chain 0.0047 0.4738 0.4738
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0042 0.0042
Echinococcus multilocularis tubulin beta 1 chain 0.0076 1 1
Loa Loa (eye worm) beta-tubulin 0.0076 1 1
Trypanosoma brucei beta tubulin 0.0076 1 1
Echinococcus granulosus Tubulin alpha 1 chain 0.0047 0.4738 0.4738
Plasmodium vivax tubulin gamma chain, putative 0.0047 0.4738 0.4738
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0042 0.0042
Echinococcus multilocularis tubulin subunit TubB 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin gamma chain, putative 0.0047 0.4738 0.4738
Plasmodium vivax tubulin alpha chain, putative 0.0047 0.4738 0.4738
Loa Loa (eye worm) hypothetical protein 0.0021 0.0042 0.0042
Trypanosoma brucei alpha tubulin 0.0047 0.4738 0.4738
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis tubulin beta chain, putative 0.0047 0.4738 0.4738
Echinococcus granulosus tubulin beta 1 chain 0.0076 1 1
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin alpha chain, putative 0.0027 0.1102 0.1102
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Toxoplasma gondii beta tubulin 0.0076 1 1
Schistosoma mansoni tubulin subunit alpha 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin epsilon chain, putative 0.0047 0.4738 0.4738
Plasmodium falciparum tubulin gamma chain 0.0047 0.4738 0.4738
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis taga, putative 0.0021 0.0042 0.0042
Leishmania major p-glycoprotein 0.0021 0.0042 0.0042
Echinococcus granulosus tubulin alpha chain 0.0047 0.4738 0.4738
Echinococcus multilocularis Tubulin beta 2C chain 0.0076 1 1
Mycobacterium ulcerans cell division protein FtsZ 0.002 0 0.5
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Entamoeba histolytica tubulin gamma chain 0.0047 0.4738 0.4716
Giardia lamblia Beta tubulin 0.0076 1 1
Schistosoma mansoni tubulin subunit beta 0.0076 1 1
Echinococcus multilocularis tubulin alpha 3 chain 0.0047 0.4738 0.4738
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Toxoplasma gondii beta-tubulin, putative 0.0076 1 1
Trypanosoma cruzi epsilon tubulin, putative 0.0047 0.4738 0.4738
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0042 0.0042
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0042 0.0042
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0042 0.0042
Treponema pallidum cell division protein FtsZ 0.002 0 0.5
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0042 0.0042
Schistosoma mansoni tubulin subunit epsilon 0.0047 0.4738 0.4738
Echinococcus granulosus Tubulin beta 2C chain 0.0076 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Echinococcus multilocularis tubulin gamma 1 chain 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin beta chain, putative 0.0076 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0042 0.0042
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0076 1 1
Loa Loa (eye worm) tubulin alpha chain 0.0047 0.4738 0.4738
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Echinococcus multilocularis tubulin alpha chain 0.0047 0.4738 0.4738
Plasmodium falciparum tubulin epsilon chain, putative 0.0047 0.4738 0.4738
Trypanosoma brucei beta tubulin 0.0076 1 1
Leishmania major gamma-tubulin 0.0047 0.4738 0.4738
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0042 0.0042
Loa Loa (eye worm) BEN-1 protein 0.0076 1 1
Entamoeba histolytica tubulin family protein 0.0076 1 1
Loa Loa (eye worm) tubulin alpha-2 chain 0.0047 0.4738 0.4738
Trypanosoma brucei epsilon tubulin 0.0047 0.4738 0.4738
Echinococcus multilocularis beta tubulin 0.0076 1 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0042 0.0042
Leishmania major beta tubulin 0.0076 1 1
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0042 0.0042
Echinococcus granulosus tubulin epsilon chain 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0027 0.1102 0.1102
Trichomonas vaginalis tubulin epsilon chain, putative 0.0076 1 1
Toxoplasma gondii tubulin/FtsZ family, GTPase domain-containing protein 0.0047 0.4738 0.4738
Leishmania major beta tubulin 0.0076 1 1
Echinococcus granulosus tubulin subunit TubB 0.0047 0.4738 0.4738
Leishmania major beta tubulin 0.0076 1 1
Echinococcus granulosus tubulin alpha chain 0.0047 0.4738 0.4738
Echinococcus granulosus Tubulin beta 2C chain 0.0076 1 1
Trichomonas vaginalis tubulin alpha chain, putative 0.0076 1 1
Echinococcus multilocularis peroxisome assembly protein 26 0.0047 0.4738 0.4738
Trichomonas vaginalis abcb9, putative 0.0021 0.0042 0.0042
Leishmania major beta tubulin 0.0076 1 1
Brugia malayi Tubulin alpha-2 chain 0.0047 0.4738 0.4738
Echinococcus multilocularis ATP binding cassette sub family B 0.002 0.0002 0.0002
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0042 0.0042
Leishmania major beta tubulin 0.0076 1 1
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0042 0.0042
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Echinococcus multilocularis Tubulin alpha 1 chain 0.0047 0.4738 0.4738
Echinococcus granulosus Tubulin beta 2C chain 0.0076 1 1
Echinococcus granulosus tubulin gamma 1 chain 0.0047 0.4738 0.4738
Plasmodium vivax tubulin alpha chain, putative 0.0047 0.4738 0.4738
Echinococcus multilocularis Tubulin beta 2C chain 0.0076 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0042 0.0042
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0042 0.0042
Echinococcus multilocularis hypothetical protein 0.0047 0.4738 0.4738
Trypanosoma brucei epsilon tubulin 0.0047 0.4738 0.4738
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Loa Loa (eye worm) alpha-tubulin 0.0047 0.4738 0.4738
Leishmania major beta tubulin 0.0076 1 1
Schistosoma mansoni tubulin subunit beta 0.0076 1 1
Trypanosoma brucei alpha tubulin 0.0047 0.4738 0.4738
Echinococcus granulosus peroxisome assembly protein 26 0.0047 0.4738 0.4738
Loa Loa (eye worm) alpha-tubulin isotype 2 0.0027 0.1102 0.1102
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0042 0.0042
Trichomonas vaginalis abcb9, putative 0.0021 0.0042 0.0042
Brugia malayi Tubulin alpha chain 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin alpha-1 chain, putative 0.0027 0.1102 0.1102
Trypanosoma cruzi epsilon tubulin, putative 0.0047 0.4738 0.4738
Trichomonas vaginalis abcb9, putative 0.0021 0.0042 0.0042
Loa Loa (eye worm) tubulin beta-4 chain 0.0076 1 1
Trichomonas vaginalis tubulin beta chain, putative 0.0047 0.4738 0.4738
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0042 0.0042
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.002 0.0002 0.0002
Echinococcus multilocularis beta tubulin 0.0076 1 1
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0042 0.0042
Trypanosoma brucei beta tubulin 0.0076 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0042 0.0042
Trypanosoma brucei beta tubulin 0.0076 1 1
Loa Loa (eye worm) tubulin alpha 2 0.0027 0.1102 0.1102
Brugia malayi Tubulin alpha-2 chain 0.0047 0.4738 0.4738
Entamoeba histolytica tubulin alpha-1 chain 0.0047 0.4738 0.4716
Echinococcus multilocularis tubulin alpha chain 0.0047 0.4738 0.4738
Loa Loa (eye worm) BEN-1 protein 0.0076 1 1
Brugia malayi ABC transporter family protein 0.0021 0.0042 0.0042
Echinococcus granulosus tubulin alpha 3 chain 0.0047 0.4738 0.4738
Schistosoma mansoni alpha tubulin 0.0047 0.4738 0.4738
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0042 0.0042
Leishmania major beta tubulin 0.0076 1 1
Plasmodium falciparum alpha tubulin 2 0.0047 0.4738 0.4738
Schistosoma mansoni multidrug resistance protein 0.0021 0.0042 0.0042
Trichomonas vaginalis tubulin, putative 0.0027 0.1102 0.1102
Echinococcus multilocularis tubulin alpha 3 chain 0.0047 0.4738 0.4738
Brugia malayi tubulin alpha-2 chain 0.0047 0.4738 0.4738
Giardia lamblia Beta tubulin 0.0076 1 1
Echinococcus granulosus tubulin alpha chain 0.0047 0.4738 0.4738
Echinococcus granulosus Tubulin beta 2C chain 0.0076 1 1
Entamoeba histolytica tubulin family protein 0.0076 1 1
Giardia lamblia Alpha-tubulin 0.0047 0.4738 0.4738
Leishmania major beta tubulin 0.0076 1 1
Leishmania major beta tubulin 0.0076 1 1
Leishmania major beta tubulin 0.0076 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0002
Giardia lamblia Alpha-tubulin 0.0047 0.4738 0.4738
Trypanosoma brucei tubulin gamma chain 0.0047 0.4738 0.4738
Trypanosoma cruzi beta tubulin, putative 0.0076 1 1
Leishmania major alpha tubulin 0.0047 0.4738 0.4738
Trichomonas vaginalis tubulin alpha chain, putative 0.0027 0.1102 0.1102
Echinococcus granulosus tubulin alpha chain 0.0047 0.4738 0.4738
Mycobacterium leprae cell division protein FtsZ 0.002 0 0.5
Echinococcus multilocularis tubulin alpha 1C chain 0.0047 0.4738 0.4738
Schistosoma mansoni tubulin subunit beta 0.0076 1 1
Leishmania major beta tubulin 0.0076 1 1
Leishmania major epsilon tubulin, putative 0.0047 0.4738 0.4738
Trypanosoma brucei alpha tubulin 0.0047 0.4738 0.4738
Entamoeba histolytica tubulin alpha chain, putative 0.0047 0.4738 0.4716
Schistosoma mansoni tubulin subunit gamma 0.0047 0.4738 0.4738
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0042 0.5
Schistosoma mansoni multidrug resistance protein 0.0021 0.0042 0.0042
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0042 0.0042
Leishmania major beta tubulin 0.0076 1 1
Leishmania major beta tubulin 0.0076 1 1
Trichomonas vaginalis tubulin beta chain, putative 0.0047 0.4738 0.4738
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0042 0.0042
Trichomonas vaginalis tubulin beta chain, putative 0.0047 0.4738 0.4738

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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