Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.1016 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0199 | 0.6025 | 0.5575 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0054 | 0.1016 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0199 | 0.6025 | 0.5575 |
Brugia malayi | TAR-binding protein | 0.0199 | 0.6025 | 0.5875 |
Brugia malayi | RNA binding protein | 0.0199 | 0.6025 | 0.5875 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.01 | 0.2599 | 0.4314 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0106 | 0.2828 | 0.4695 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 0.7883 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0315 | 1 | 1 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0162 | 0.4749 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 0.5 |
Brugia malayi | Probable ClpP-like protease | 0.0162 | 0.4749 | 0.4552 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0199 | 0.6025 | 0.5875 |
Echinococcus multilocularis | GPCR, family 2 | 0.01 | 0.2599 | 0.4314 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0252 | 0.7826 | 0.758 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.6575 | 0.6187 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0215 | 0.6575 | 0.6446 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0252 | 0.7826 | 0.758 |
Schistosoma mansoni | hypothetical protein | 0.0215 | 0.6575 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.6025 | 0.9164 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.2599 | 0.3954 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.1016 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.01 | 0.2599 | 0.4314 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.2599 | 0.3954 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 0.7883 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 0.5 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0056 | 0.1095 | 0.0211 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.01 | 0.2599 | 0.4314 |
Echinococcus granulosus | tar DNA binding protein | 0.0199 | 0.6025 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.01 | 0.2599 | 0.2321 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.4749 | 0.4156 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0106 | 0.2828 | 0.5 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0056 | 0.1095 | 0.0211 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.1016 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0199 | 0.6025 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0162 | 0.4749 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0162 | 0.4749 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.6025 | 0.9164 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0106 | 0.2828 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.2599 | 0.3954 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.2599 | 0.3954 |
Brugia malayi | Latrophilin receptor protein 2 | 0.01 | 0.2599 | 0.2321 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0106 | 0.2828 | 0.4744 |
Brugia malayi | MH2 domain containing protein | 0.0252 | 0.7826 | 0.7744 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0315 | 1 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.01 | 0.2599 | 0.1762 |
Brugia malayi | hypothetical protein | 0.0054 | 0.1016 | 0.0677 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.01 | 0.2599 | 0.4314 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.01 | 0.2599 | 0.4314 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.6025 | 0.9164 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0162 | 0.4749 | 0.7224 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.6025 | 0.9164 |
Loa Loa (eye worm) | RNA binding protein | 0.0199 | 0.6025 | 0.5575 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0106 | 0.2828 | 0.4695 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0162 | 0.4749 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0056 | 0.1095 | 0.0211 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2599 | 0.1762 |
Schistosoma mansoni | tar DNA-binding protein | 0.0199 | 0.6025 | 0.9164 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 1 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0162 | 0.4749 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.