Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | fibroinase | 0.0325 | 0.2924 | 0.2198 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0224 | 0.093 | 0.3182 |
Echinococcus multilocularis | cysteine protease | 0.0325 | 0.2924 | 0.2924 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0684 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0325 | 0.2924 | 0.2198 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.2924 | 0.2198 |
Echinococcus granulosus | cathepsin l1 | 0.0224 | 0.093 | 0.093 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0325 | 0.2924 | 0.2924 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2924 | 0.2924 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0263 | 0.1716 | 0.5868 |
Loa Loa (eye worm) | cysteine protease | 0.0325 | 0.2924 | 0.2198 |
Giardia lamblia | Cathepsin B precursor | 0.0263 | 0.1716 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0684 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0684 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0224 | 0.093 | 0.093 |
Onchocerca volvulus | Cathepsin L homolog | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0325 | 0.2924 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0325 | 0.2924 | 0.2924 |
Giardia lamblia | Cathepsin B precursor | 0.0263 | 0.1716 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0263 | 0.1716 | 0.1716 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2924 | 0.2924 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0224 | 0.093 | 0.093 |
Onchocerca volvulus | 0.0325 | 0.2924 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0684 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0684 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0224 | 0.093 | 0.093 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0325 | 0.2924 | 0.2924 |
Onchocerca volvulus | 0.0325 | 0.2924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0684 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0325 | 0.2924 | 1 |
Plasmodium vivax | vivapain-2 | 0.0325 | 0.2924 | 1 |
Plasmodium vivax | vivapain-2 | 0.0325 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0325 | 0.2924 | 0.2924 |
Onchocerca volvulus | Cathepsin L homolog | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0224 | 0.093 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0224 | 0.093 | 0.093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0325 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0224 | 0.093 | 0.093 |
Onchocerca volvulus | 0.0325 | 0.2924 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0325 | 0.2924 | 0.2924 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0224 | 0.093 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Echinococcus granulosus | cathepsin b | 0.0684 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0263 | 0.1716 | 0.5868 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0224 | 0.093 | 0.093 |
Toxoplasma gondii | cathepsin CPL | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0263 | 0.1716 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0325 | 0.2924 | 0.2924 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2924 | 0.2924 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0325 | 0.2924 | 1 |
Onchocerca volvulus | 0.0325 | 0.2924 | 1 | |
Onchocerca volvulus | 0.0325 | 0.2924 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2924 | 0.2924 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0325 | 0.2924 | 0.2198 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2924 | 0.2924 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Onchocerca volvulus | 0.0325 | 0.2924 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0325 | 0.2924 | 0.2924 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0325 | 0.2924 | 0.2924 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0325 | 0.2924 | 0.2924 |
Leishmania major | cathepsin L-like protease | 0.0325 | 0.2924 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0325 | 0.2924 | 1 |
Onchocerca volvulus | 0.0325 | 0.2924 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0684 | 1 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0263 | 0.1716 | 0.0866 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0263 | 0.1716 | 0.1716 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0684 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0325 | 0.2924 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2924 | 0.2924 |
Brugia malayi | Cathepsin L-like precursor | 0.0325 | 0.2924 | 0.2924 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0325 | 0.2924 | 0.2924 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0684 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0325 | 0.2924 | 0.2924 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0325 | 0.2924 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0325 | 0.2924 | 0.2198 |
Leishmania major | cysteine peptidase A (CPA) | 0.0325 | 0.2924 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0325 | 0.2924 | 0.2924 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0325 | 0.2924 | 0.2924 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.