Detailed information for compound 1485443

Basic information

Technical information
  • TDR Targets ID: 1485443
  • Name: N-(4-methyl-3-morpholin-4-ylsulfonylphenyl)-2 ,3-dihydro-1,4-benzodioxine-2-carboxamide
  • MW: 418.463 | Formula: C20H22N2O6S
  • H donors: 1 H acceptors: 3 LogP: 1.72 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(C1COc2c(O1)cccc2)Nc1ccc(c(c1)S(=O)(=O)N1CCOCC1)C
  • InChi: 1S/C20H22N2O6S/c1-14-6-7-15(12-19(14)29(24,25)22-8-10-26-11-9-22)21-20(23)18-13-27-16-4-2-3-5-17(16)28-18/h2-7,12,18H,8-11,13H2,1H3,(H,21,23)
  • InChiKey: DTUUXDIGBXNINJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(4-methyl-3-morpholinosulfonyl-phenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
  • N-(4-methyl-3-morpholinosulfonylphenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
  • N-(4-methyl-3-morpholin-4-ylsulfonyl-phenyl)-2,3-dihydro-1,4-benzodioxine-2-carboxamide
  • T5380709

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis glutaminase, putative 0.0278 0.3174 0.9671
Brugia malayi orphan nuclear receptor NR2E1 0.0015 0.0017 0.0031
Schistosoma mansoni lamin 0.0028 0.0176 0.0179
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0127 0.1361 0.1379
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0032 0.0216 0.0219
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0032 0.0216 0.0387
Echinococcus granulosus cpg binding protein 0.0062 0.0583 0.0591
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0032 0.0216 0.04
Loa Loa (eye worm) acetylcholinesterase 1 0.0331 0.3809 0.7046
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.002 0.0033
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0015 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0084 0.0851 0.0862
Schistosoma mansoni BC026374 protein (S09 family) 0.0056 0.0509 0.0516
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0029 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0292 0.9571
Echinococcus multilocularis geminin 0.0347 0.3994 0.3994
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0255 0.0258
Echinococcus multilocularis lamin 0.0028 0.0176 0.0176
Schistosoma mansoni nuclear hormone receptor 0.0032 0.0216 0.0219
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.004 0.004
Brugia malayi Carboxylesterase family protein 0.0056 0.0509 0.0942
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0017 0.0038 0.0039
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0292 0.1248
Echinococcus multilocularis thyroid hormone receptor alpha 0.0032 0.0216 0.0216
Echinococcus granulosus SWI:SNF matrix associated 0.0017 0.0042 0.0043
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0149 0.4894
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0226 0.7417
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0017 0.0042 0.0354
Giardia lamblia NADH oxidase lateral transfer candidate 0.0013 0 0.5
Brugia malayi hypothetical protein 0.0017 0.0039 0.0072
Loa Loa (eye worm) hypothetical protein 0.0331 0.3809 0.7046
Schistosoma mansoni steroid hormone receptor ad4bp 0.0032 0.0216 0.0219
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0038 0.0038
Brugia malayi Carboxylesterase family protein 0.0331 0.3809 0.7047
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0032 0.0216 0.0219
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0104 0.1081 0.1989
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0042 0.1382
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0017 0.0042 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0144 0.1561 0.2887
Echinococcus granulosus smad 0.0017 0.004 0.004
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0207 0.2323 0.2354
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0292 0.0888
Onchocerca volvulus 0.0056 0.0509 0.093
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0007 0.0022
Toxoplasma gondii thioredoxin reductase 0.0039 0.0305 0.2562
Schistosoma mansoni hypothetical protein 0.0837 0.9869 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0286 0.0526
Brugia malayi Glycosyl hydrolases family 31 protein 0.017 0.188 0.3478
Loa Loa (eye worm) nuclear receptor NHR-67 0.0015 0.0017 0.0028
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0292 0.0888
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0089 0.0902 0.8837
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0017 0.0017
Echinococcus multilocularis Smad4 0.0017 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Echinococcus multilocularis SWI:SNF matrix associated 0.0017 0.0042 0.0042
Schistosoma mansoni smad1 5 8 and 0.0017 0.004 0.004
Schistosoma mansoni nuclear receptor 0.0015 0.0017 0.0017
Echinococcus granulosus nuclear receptor nhr 48 0.0015 0.0017 0.0017
Brugia malayi tailless protein 0.0015 0.0017 0.0031
Echinococcus granulosus expressed conserved protein 0.0192 0.2137 0.2165
Echinococcus granulosus GPCR family 2 0.0048 0.042 0.0425
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0017 0.0018
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.188 0.188
Mycobacterium tuberculosis Carboxylesterase LipT 0.0056 0.0509 0.4993
Brugia malayi conserved hypotetical protein 0.0015 0.0017 0.0031
Echinococcus granulosus Nuclear hormone receptor HR96 0.0015 0.0017 0.0017
Entamoeba histolytica heat shock transcription factor, putative 0.0104 0.1081 0.4713
Echinococcus granulosus FTZ F1 alpha 0.0032 0.0216 0.0219
Entamoeba histolytica hypothetical protein 0.0074 0.0721 0.3132
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0017 0.0017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0216 0.0216
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0032 0.0216 0.0397
Brugia malayi nuclear hormone receptor 0.0015 0.0017 0.0031
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.004 0.004
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0099 0.102 1
Schistosoma mansoni cpg binding protein 0.0059 0.0543 0.055
Schistosoma mansoni hypothetical protein 0.0017 0.0042 0.0043
Echinococcus multilocularis sterol regulatory element binding protein 0.0088 0.0889 0.0889
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0292 0.2453
Echinococcus granulosus neuroligin 0.0056 0.0509 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0889 0.2708
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0286 0.0286
Echinococcus granulosus lamin 0.0028 0.0176 0.0179
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0029 0.0029
Brugia malayi nuclear receptor NHR-67 0.0015 0.0017 0.0031
Plasmodium vivax glutathione reductase, putative 0.0039 0.0305 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0032 0.0216 0.0219
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0032 0.0216 0.0216
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0032 0.0216 0.04
Brugia malayi Thioredoxin reductase 0.0039 0.0305 0.0563
Onchocerca volvulus 0.0056 0.0509 0.093
Brugia malayi hypothetical protein 0.0465 0.5406 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0072 0.0072
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0089 0.0902 0.8837
Schistosoma mansoni lamin 0.0028 0.0176 0.0179
Loa Loa (eye worm) hypothetical protein 0.0056 0.0509 0.094
Echinococcus multilocularis BC026374 protein (S09 family) 0.0056 0.0509 0.0509
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0292 0.0888
Loa Loa (eye worm) nuclear hormone receptor 0.0015 0.0017 0.0028
Onchocerca volvulus 0.0015 0.0017 0.0018
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0226 0.0229
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0032 0.0216 0.04
Schistosoma mansoni smad1 5 8 and 0.0017 0.004 0.004
Brugia malayi nuclear hormone receptor 0.0032 0.0216 0.04
Trypanosoma brucei RNA helicase, putative 0.0211 0.237 1
Schistosoma mansoni hypothetical protein 0.0347 0.3994 0.4047
Schistosoma mansoni hypothetical protein 0.0105 0.1094 0.1109
Schistosoma mansoni patched 1 0.0088 0.0889 0.09
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.004 0.004
Brugia malayi MH2 domain containing protein 0.0017 0.004 0.0073
Loa Loa (eye worm) MH2 domain-containing protein 0.0246 0.2791 0.5162
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0144 0.1561 0.1561
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0286 0.029
Brugia malayi steroid hormone receptor 0.0032 0.0216 0.04
Brugia malayi brahma associated protein 60 kDa 0.0017 0.0042 0.0078
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0032 0.0216 0.0219
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0016 0.0029 0.003
Echinococcus granulosus lysosomal alpha glucosidase 0.017 0.188 0.1905
Echinococcus multilocularis smad 0.0017 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0084 0.0851 0.0862
Onchocerca volvulus Protein ultraspiracle homolog 0.0032 0.0216 0.0387
Schistosoma mansoni RAR-like nuclear receptor 0.0032 0.0216 0.0219
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0056 0.0509 0.0516
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0144 0.1561 0.1581
Schistosoma mansoni smad 0.0017 0.004 0.004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0253 0.2865 0.5299
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0226 0.7417
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0226 0.0226
Echinococcus multilocularis GPCR, family 2 0.0048 0.042 0.042
Brugia malayi Carboxylesterase family protein 0.0331 0.3809 0.7047
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0226 0.7417
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.017 0.188 0.3476
Brugia malayi nuclear receptor NHR-88 0.0015 0.0017 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0022
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0056 0.0509 0.0516
Schistosoma mansoni gliotactin 0.0056 0.0509 0.0516
Echinococcus granulosus geminin 0.0347 0.3994 0.4047
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0292 0.0888
Loa Loa (eye worm) transcription factor SMAD2 0.0246 0.2791 0.5162
Loa Loa (eye worm) hypothetical protein 0.0056 0.0509 0.094
Schistosoma mansoni microtubule-associated protein tau 0.0722 0.8486 0.8599
Echinococcus granulosus acetylcholinesterase 0.0331 0.3809 0.386
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0292 0.0888
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0072 0.0073
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0032 0.0216 0.0219
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0017 0.0017
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0286 0.0286
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0017 0.0042 0.0354
Trypanosoma cruzi trypanothione reductase, putative 0.0039 0.0305 1
Plasmodium falciparum thioredoxin reductase 0.0039 0.0305 1
Onchocerca volvulus 0.0287 0.3282 0.6065
Brugia malayi hypothetical protein 0.0026 0.0149 0.0276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0032 0.0216 0.0397
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.042 0.0425
Brugia malayi hypothetical protein 0.0015 0.0017 0.0031
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0226 0.0953
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Brugia malayi MH1 domain containing protein 0.0017 0.004 0.0073
Brugia malayi Carboxylesterase family protein 0.0056 0.0509 0.0942
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0032 0.0216 0.0219
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.0216 0.04
Mycobacterium tuberculosis Probable oxidoreductase 0.0099 0.102 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Brugia malayi nuclear receptor RXR 0.0017 0.0038 0.007
Echinococcus multilocularis expressed conserved protein 0.0192 0.2137 0.2137
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0286 0.029
Schistosoma mansoni nuclear hormone receptor 0.0015 0.0017 0.0017
Schistosoma mansoni alpha glucosidase 0.0038 0.0292 0.0295
Echinococcus multilocularis carboxylesterase 5A 0.0331 0.3809 0.3809
Echinococcus granulosus lamin dm0 0.0028 0.0176 0.0179
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0226 0.7417
Schistosoma mansoni hypothetical protein 0.0084 0.0851 0.0862
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Brugia malayi CXXC zinc finger family protein 0.0059 0.0543 0.1004
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0216 0.0219
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0038 0.0038
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0069 0.0129
Treponema pallidum NADH oxidase 0.0013 0 0.5
Echinococcus multilocularis ecdysone induced protein 78C 0.0032 0.0216 0.0216
Loa Loa (eye worm) glutaminase 0.0278 0.3174 0.587
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.0216 0.0219
Echinococcus multilocularis Niemann Pick C1 protein 0.0204 0.2285 0.2285
Echinococcus multilocularis cpg binding protein 0.0062 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0028 0.017 0.0312
Schistosoma mansoni hypothetical protein 0.0017 0.0042 0.0043
Entamoeba histolytica hypothetical protein 0.0074 0.0721 0.3132
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.004 0.007
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0226 0.0229
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0226 0.1901
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0007 0.0022
Brugia malayi intermediate filament protein 0.0028 0.0176 0.0326
Brugia malayi Pre-SET motif family protein 0.0037 0.0286 0.0529
Loa Loa (eye worm) glutaminase 2 0.0278 0.3174 0.587
Brugia malayi glutathione reductase 0.0039 0.0305 0.0563
Loa Loa (eye worm) hypothetical protein 0.0056 0.0509 0.094
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0032 0.0216 0.0219
Echinococcus granulosus Smad4 0.0017 0.004 0.004
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0015 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0056 0.0509 0.094
Onchocerca volvulus 0.0056 0.0509 0.093
Onchocerca volvulus 0.0015 0.0017 0.0018
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0292 0.9571
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.1675 0.3099
Schistosoma mansoni intermediate filament proteins 0.0028 0.0176 0.0179
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0017 0.0042 0.0043
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0032 0.0216 0.0397
Brugia malayi MH2 domain containing protein 0.0017 0.004 0.0073
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0292 0.0537
Onchocerca volvulus 0.0056 0.0509 0.093
Entamoeba histolytica hypothetical protein 0.0074 0.0721 0.3132
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0216 0.04
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0017 0.0042 0.1382
Brugia malayi hypothetical protein 0.0015 0.0017 0.0031
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0149 0.1254
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0149 0.4894
Onchocerca volvulus 0.0099 0.1019 0.1875
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0226 0.0226
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0126 0.1348 0.1366
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0226 0.2214
Brugia malayi CHE-14 protein 0.0088 0.0889 0.1644
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0216 0.0219
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.1675 0.3097
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0017 0.0038 0.0068
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0029 0.003
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0292 0.0888
Echinococcus multilocularis thioredoxin glutathione reductase 0.0039 0.0311 0.0311
Onchocerca volvulus 0.0465 0.5406 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.1094 0.2021
Echinococcus multilocularis protein dispatched 1 0.01 0.1037 0.1037
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0032 0.0216 0.0216
Leishmania major hypothetical protein, conserved 0.0026 0.0149 0.4894
Schistosoma mansoni smad1 5 8 and 0.0017 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0056 0.0509 0.094
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0002 0.0002
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0286 0.2405
Echinococcus granulosus Niemann Pick C1 protein 0.0204 0.2285 0.2316
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0017 0.0042 0.1382
Schistosoma mansoni hypothetical protein 0.0211 0.237 0.2401
Schistosoma mansoni cpg binding protein 0.0062 0.0583 0.0591
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0032 0.0216 0.0397
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0149 0.4894
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0292 0.1248
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0149 0.4894
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.042 0.0425
Brugia malayi hypothetical protein 0.0017 0.0038 0.007
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0226 0.0226
Echinococcus multilocularis acetylcholinesterase 0.0331 0.3809 0.3809
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0292 0.0888
Schistosoma mansoni hypothetical protein 0.0048 0.042 0.0425
Schistosoma mansoni brg-1 associated factor 0.0017 0.0042 0.0043
Brugia malayi Steroid receptor seven-up type 2 0.0032 0.0216 0.04
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0017 0.0031
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0038 0.0039
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0089 0.0902 0.8837
Brugia malayi hypothetical protein 0.0056 0.0509 0.0942
Brugia malayi MH1 domain containing protein 0.0017 0.004 0.0073
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0007 0.003
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0032 0.0216 0.04
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0017 0.0042 0.1382
Loa Loa (eye worm) hypothetical protein 0.0331 0.3809 0.7046
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Echinococcus granulosus Protein patched homolog 1 0.0088 0.0889 0.09
Echinococcus granulosus thioredoxin glutathione reductase 0.0039 0.0311 0.0315
Brugia malayi Carboxylesterase family protein 0.0056 0.0509 0.0942
Loa Loa (eye worm) hypothetical protein 0.0028 0.0176 0.0324
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0292 0.0888
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0056 0.0509 0.0516
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0204 0.2285 1
Onchocerca volvulus Bile acid receptor homolog 0.0032 0.0216 0.0387
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0056 0.0509 0.4993
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0032 0.0216 0.04
Schistosoma mansoni nuclear receptor nhr-48 0.0015 0.0017 0.0017
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0007 0.0022
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.188 0.188
Loa Loa (eye worm) hypothetical protein 0.0465 0.5406 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.001
Echinococcus granulosus thyroid hormone receptor alpha 0.0015 0.0017 0.0017
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0331 0.3809 0.386
Brugia malayi Smad1 0.0017 0.004 0.0073
Schistosoma mansoni neuroligin 3 (S09 family) 0.0056 0.0509 0.0516
Loa Loa (eye worm) Smad1 0.0017 0.004 0.007
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0099 0.102 1
Echinococcus multilocularis protein patched 0.0088 0.0889 0.0889
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0 0.5
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0176 0.0324
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Schistosoma mansoni zinc finger protein 0.0015 0.0017 0.0017
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0292 0.0295
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Brugia malayi Pre-SET motif family protein 0.0253 0.2865 0.5301
Echinococcus granulosus para nitrobenzyl esterase 0.0056 0.0509 0.0516
Brugia malayi brahma associated protein 60 kDa 0.0017 0.0042 0.0078
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0032 0.0216 0.0219
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0088 0.0889 0.1641
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0038 0.0068
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0286 0.029
Schistosoma mansoni glutaminase 0.0278 0.3174 0.3216
Brugia malayi photoreceptor-specific nuclear receptor 0.0032 0.0216 0.04
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.002 0.0036
Schistosoma mansoni Smad4 0.0017 0.004 0.004
Loa Loa (eye worm) carboxylesterase 0.0056 0.0509 0.094
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0226 0.1901
Loa Loa (eye worm) hypothetical protein 0.0153 0.1675 0.3097
Echinococcus multilocularis musashi 0.0028 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0048 0.042 0.0774
Echinococcus multilocularis nuclear receptor nhr 48 0.0015 0.0017 0.0017
Brugia malayi nuclear hormone receptor family member nhr-6 0.0015 0.0017 0.0031
Schistosoma mansoni hypothetical protein 0.0048 0.042 0.0425
Brugia malayi SWIB/MDM2 domain containing protein 0.0017 0.0042 0.0078
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0056 0.0509 0.0516
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0013 0 0.5
Entamoeba histolytica heat shock transcription factor, putative 0.0104 0.1081 0.4713
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0226 0.7417
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0015 0.0017 0.0017
Onchocerca volvulus 0.0028 0.0176 0.0313
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0017 0.0038 0.0038
Echinococcus granulosus Niemann Pick C1 protein 0.0292 0.3335 0.338
Onchocerca volvulus 0.0059 0.0543 0.0992
Chlamydia trachomatis SWIB complex protein 0.0017 0.0042 1
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0017 0.0042 0.0075
Brugia malayi isocitrate dehydrogenase 0.0032 0.0226 0.0418
Loa Loa (eye worm) hypothetical protein 0.0204 0.2285 0.4226
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0176 0.0326
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0029 0.003
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0038 0.007
Echinococcus multilocularis microtubule associated protein 2 0.0722 0.8486 0.8486
Trypanosoma brucei glucosidase, putative 0.0038 0.0292 0.123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0032 0.0216 0.0219
Mycobacterium tuberculosis Probable dehydrogenase 0.0089 0.0902 0.8837
Loa Loa (eye worm) brahma associated protein 0.0017 0.0042 0.0075
Brugia malayi nuclear receptor NHR-88 0.0032 0.0216 0.04
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0099 0.102 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0226 0.0415
Loa Loa (eye worm) hypothetical protein 0.0088 0.0889 0.1641
Schistosoma mansoni alpha-glucosidase 0.0147 0.1596 0.1617
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0038 0.007
Brugia malayi MH2 domain containing protein 0.0246 0.2791 0.5163
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0042 0.0128
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Mycobacterium tuberculosis Probable reductase 0.0089 0.0902 0.8837
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0015 0.0017 0.0017
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0022
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.042 0.0776
Onchocerca volvulus 0.0017 0.0042 0.0065
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0007 0.0237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0144 0.1561 0.2885
Brugia malayi Latrophilin receptor protein 2 0.0048 0.042 0.0776
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.042 0.042
Echinococcus granulosus dnaJ subfamily B 0.0837 0.9869 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0056 0.0509 0.1552
Echinococcus multilocularis lamin dm0 0.0028 0.0176 0.0176
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0022
Loa Loa (eye worm) thioredoxin reductase 0.0039 0.0305 0.0561
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.042 0.0774
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0056 0.0509 0.4993
Schistosoma mansoni retinoic acid receptor RXR 0.0032 0.0216 0.0219
Schistosoma mansoni hypothetical protein 0.0048 0.042 0.0425
Brugia malayi hypothetical protein 0.0017 0.0038 0.007
Loa Loa (eye worm) hypothetical protein 0.0056 0.0509 0.094
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0032 0.0216 0.0397
Brugia malayi HSF-type DNA-binding domain containing protein 0.0104 0.1081 0.2
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.1675 0.3099
Loa Loa (eye worm) hypothetical protein 0.0104 0.1081 0.1997
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0226 0.0418
Schistosoma mansoni coup transcription factor 0.0032 0.0216 0.0219
Echinococcus granulosus X box binding protein 1 0.0301 0.3449 0.3495
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0149 0.0629
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0543 0.1001
Echinococcus multilocularis neuroligin 0.0056 0.0509 0.0509
Loa Loa (eye worm) carboxylesterase 0.0056 0.0509 0.094
Trichomonas vaginalis set domain proteins, putative 0.0287 0.3282 1
Mycobacterium ulcerans glutaminase 0.0278 0.3174 1
Schistosoma mansoni neuropeptide receptor 0.0017 0.0038 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0032 0.0216 0.0397
Schistosoma mansoni hypothetical protein 0.0074 0.0721 0.073
Onchocerca volvulus 0.0037 0.0286 0.0516
Entamoeba histolytica heat shock transcription factor, putative 0.0104 0.1081 0.4713
Loa Loa (eye worm) hypothetical protein 0.0026 0.0149 0.0273
Loa Loa (eye worm) histone methyltransferase 0.002 0.0072 0.0131
Loa Loa (eye worm) steroid hormone receptor 0.0032 0.0216 0.0397
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0226 0.0953
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Mycobacterium ulcerans carboxylesterase, LipT 0.0056 0.0509 0.1605
Schistosoma mansoni acetylcholinesterase 0.0056 0.0509 0.0516
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0089 0.0902 0.8837
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0721 0.073
Echinococcus granulosus sterol regulatory element binding protein 0.0088 0.0889 0.09
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0176 0.0324
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0015 0.0017 0.0028
Brugia malayi Nuclear hormone receptor E75 0.0015 0.0017 0.0031
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0015 0.0017 0.0017
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0032 0.0216 0.0216
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0032 0.0216 0.0219
Loa Loa (eye worm) carboxylesterase 0.0331 0.3809 0.7046
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0226 0.0226
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.004 0.004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0039 0.0305 0.2985
Brugia malayi Carboxylesterase family protein 0.0056 0.0509 0.0942
Leishmania major trypanothione reductase 0.0039 0.0305 1
Echinococcus granulosus microtubule associated protein 2 0.0722 0.8486 0.8599
Loa Loa (eye worm) hypothetical protein 0.0107 0.1125 0.2078
Plasmodium vivax SET domain protein, putative 0.0037 0.0286 0.9385
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0292 0.0539
Brugia malayi Niemann-Pick C1 protein precursor 0.0204 0.2285 0.4227
Schistosoma mansoni nuclear receptor 0.0015 0.0017 0.0017
Echinococcus multilocularis acetylcholinesterase 0.0331 0.3809 0.3809
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0056 0.0509 0.0509
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0286 0.029
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0007 0.0237
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0017 0.0038 0.0039
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.1094 0.2024
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0292 0.9571
Echinococcus multilocularis para nitrobenzyl esterase 0.0056 0.0509 0.0509
Schistosoma mansoni hypothetical protein 0.0347 0.3994 0.4047
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Schistosoma mansoni hypothetical protein 0.0301 0.3449 0.3495
Echinococcus multilocularis dnaJ subfamily B 0.0837 0.9869 0.9869
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0292 0.0292
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0721 0.0721
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0216 0.04
Echinococcus granulosus intermediate filament protein 0.0028 0.0176 0.0179
Schistosoma mansoni thyroid hormone receptor 0.0032 0.0216 0.0219
Schistosoma mansoni hypothetical protein 0.0017 0.0042 0.0043
Echinococcus multilocularis SWI:SNF matrix associated 0.0017 0.0042 0.0042
Echinococcus granulosus acetylcholinesterase 0.0331 0.3809 0.386
Onchocerca volvulus 0.0028 0.0176 0.0313
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0216 0.04
Plasmodium falciparum glutathione reductase 0.0039 0.0305 1
Schistosoma mansoni hypothetical protein 0.0084 0.0851 0.0862
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0226 0.0226
Trichomonas vaginalis spcc417.12 protein, putative 0.0056 0.0509 0.1552
Echinococcus multilocularis FTZ F1 alpha 0.0032 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Onchocerca volvulus 0.0056 0.0509 0.093
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0022
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0032 0.0216 0.04
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0032 0.0216 0.04
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0292 0.0888
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0032 0.0216 0.04
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0149 0.4894
Brugia malayi ecdysteroid receptor 0.0032 0.0216 0.04
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0007 0.0237
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0721 0.073
Schistosoma mansoni cpg binding protein 0.0062 0.0583 0.0591
Brugia malayi nuclear receptor RXR 0.0015 0.0017 0.0031
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0015 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0056 0.0509 0.094
Echinococcus multilocularis Niemann Pick C1 protein 0.0292 0.3335 0.3335
Echinococcus granulosus ecdysone induced protein 78C 0.0032 0.0216 0.0219
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0015 0.0017 0.0017
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.004 0.007
Loa Loa (eye worm) DR-78 0.0015 0.0017 0.0028
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.004 0.004
Echinococcus granulosus carboxylesterase 5A 0.0331 0.3809 0.386
Plasmodium vivax thioredoxin reductase, putative 0.0039 0.0305 1
Echinococcus granulosus BC026374 protein S09 family 0.0056 0.0509 0.0516
Echinococcus multilocularis SWI:SNF matrix associated 0.0017 0.0042 0.0042
Schistosoma mansoni alpha-glucosidase 0.0147 0.1596 0.1617
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0032 0.0216 0.04
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.1189 1
Chlamydia trachomatis DNA topoisomerase I 0.0017 0.0042 1
Entamoeba histolytica hypothetical protein 0.0074 0.0721 0.3132
Brugia malayi nuclear hormone receptor family member odr-7 0.0015 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0015 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028
Onchocerca volvulus 0.0032 0.0216 0.0387
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.042 0.042
Brugia malayi hypothetical protein 0.0074 0.0721 0.1333
Schistosoma mansoni hypothetical protein 0.0048 0.042 0.0425
Brugia malayi glutaminase DH11.1 0.0278 0.3174 0.5871
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0015 0.0017 0.0017
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0032 0.0216 0.0216
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0286 0.029
Trypanosoma brucei trypanothione reductase 0.0039 0.0305 0.1285
Brugia malayi ecdysone receptor 0.0015 0.0017 0.0031
Loa Loa (eye worm) hypothetical protein 0.0032 0.0216 0.0397
Loa Loa (eye worm) glutathione reductase 0.0039 0.0305 0.0561
Echinococcus granulosus neuropeptide receptor 0.0017 0.0038 0.0039
Echinococcus multilocularis X box binding protein 1 0.0301 0.3449 0.3449
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0028

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.5858 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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