Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0073 | 0.0033 |
Giardia lamblia | Pyruvate kinase | 0.0879 | 1 | 1 |
Giardia lamblia | Pyruvate kinase | 0.0451 | 0.5054 | 0.5018 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0687 | 0.0676 |
Brugia malayi | hypothetical protein | 0.0258 | 0.2821 | 0.2812 |
Leishmania major | pyruvate kinase | 0.0879 | 1 | 1 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0879 | 1 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0073 | 0.0687 | 0.0619 |
Loa Loa (eye worm) | pyruvate kinase | 0.0879 | 1 | 1 |
Onchocerca volvulus | 0.0073 | 0.0687 | 0.065 | |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0065 | 0.005 |
Schistosoma mansoni | pyruvate kinase | 0.0879 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.1804 | 0.1791 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0073 | 0.0687 | 0.0619 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0017 | 0.004 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0879 | 1 | 1 |
Chlamydia trachomatis | pyruvate kinase | 0.0879 | 1 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.01 | 0.0067 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.004 | 0.0028 |
Echinococcus granulosus | geminin | 0.017 | 0.1804 | 0.1777 |
Schistosoma mansoni | pyruvate kinase | 0.0451 | 0.5054 | 0.5046 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0057 |
Toxoplasma gondii | ABC1 family protein | 0.0073 | 0.0687 | 0.065 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0879 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0687 | 0.0673 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.1248 | 0.1237 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0258 | 0.2821 | 0.281 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0073 | 0.0057 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.004 | 0.0007 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.0531 | 0.0499 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0451 | 0.5054 | 0.5034 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0052 | 0.0444 | 0.0429 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.0928 | 0.0897 |
Loa Loa (eye worm) | pyruvate kinase | 0.0879 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.004 | 0.0025 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Mycobacterium ulcerans | pyruvate kinase | 0.0879 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.004 | 0.0007 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0879 | 1 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.01 | 0.0067 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0164 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0687 | 0.0676 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0928 | 0.0913 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0073 | 0.0057 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0608 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0158 | 0.0145 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0879 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0094 | 0.0928 | 0.0916 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0036 | 0.002 |
Mycobacterium ulcerans | beta-lactamase | 0.0073 | 0.0687 | 0.0619 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0164 | 0.0151 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0033 | 0.0018 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0065 | 0.059 | 0.0552 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0879 | 1 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0073 | 0.0687 | 0.0619 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0036 | 0.002 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.0708 | 0.0697 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0033 | 0.0021 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.004 | 0.0025 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0451 | 0.5054 | 0.5034 |
Schistosoma mansoni | pyruvate kinase | 0.0879 | 1 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0073 | 0.004 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0687 | 0.0673 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0065 | 0.0032 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.059 | 0.0521 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0687 | 0.065 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0033 | 0.0018 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.1248 | 0.1237 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0455 | 0.0443 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0879 | 1 | 1 |
Echinococcus granulosus | pyruvate kinase | 0.0879 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0164 | 0.0131 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0255 | 0.0222 |
Echinococcus multilocularis | pyruvate kinase | 0.0451 | 0.5054 | 0.5037 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0659 | 0.0647 |
Echinococcus multilocularis | pyruvate kinase | 0.0879 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0164 | 0.0131 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0017 | 0.004 | 0.0007 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0687 | 0.0619 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.1804 | 0.1791 |
Mycobacterium ulcerans | hypothetical protein | 0.0073 | 0.0687 | 0.0619 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0073 | 0.0687 | 0.0619 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0451 | 0.5054 | 0.5034 |
Loa Loa (eye worm) | fibroinase | 0.0017 | 0.004 | 0.0028 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0928 | 0.0913 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.026 | 0.0245 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.0928 | 0.0897 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.004 | 0.0028 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.0572 | 0.0558 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0469 | 0.5265 | 0.523 |
Brugia malayi | beta-lactamase | 0.0073 | 0.0687 | 0.0676 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0455 | 0.0443 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0687 | 0.0673 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.004 | 0.0028 |
Onchocerca volvulus | 0.0028 | 0.0164 | 0.0124 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0608 | 0.0594 |
Echinococcus multilocularis | pyruvate kinase | 0.0694 | 0.7859 | 0.7852 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0879 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0258 | 0.2821 | 0.281 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.004 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0333 | 0.0321 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.004 | 0.0025 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0065 | 0.0032 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.004 | 0.0007 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.059 | 0.0521 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0127 | 0.0115 |
Echinococcus granulosus | pyruvate kinase | 0.0451 | 0.5054 | 0.5037 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0687 | 0.0676 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.0036 | 0.0003 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0608 | 0.0594 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0033 | 0.0021 |
Brugia malayi | Pyruvate kinase, alpha/beta domain containing protein | 0.0266 | 0.2913 | 0.2904 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0057 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0067 | 0.0608 | 0.0594 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0036 | 0.0003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0687 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0311 | 0.0299 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0036 | 0.002 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0073 | 0.0687 | 0.0619 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.004 | 0.0028 |
Echinococcus granulosus | pyruvate kinase | 0.0879 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.004 | 0.0025 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0036 | 0.0003 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0879 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0455 | 0.0443 |
Echinococcus multilocularis | cysteine protease | 0.0017 | 0.004 | 0.0007 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0073 | 0.0687 | 0.0656 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0687 | 0.065 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0017 | 0.004 | 0.0028 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0073 | 0.0687 | 0.0676 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0073 | 0.0687 | 0.0619 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0073 | 0.0687 | 0.0676 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.004 | 0.0025 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.059 | 0.0575 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0258 | 0.2821 | 0.2797 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0036 | 0.002 |
Echinococcus granulosus | pyruvate kinase | 0.0451 | 0.5054 | 0.5037 |
Leishmania major | cysteine peptidase A (CPA) | 0.0017 | 0.004 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0036 | 0.0023 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0258 | 0.2821 | 0.2797 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0455 | 0.0443 |
Loa Loa (eye worm) | cysteine protease | 0.0017 | 0.004 | 0.0028 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0065 | 0.059 | 0.0558 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0613 | 0.6925 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.2693 | 0.2684 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0065 | 0.059 | 0.0521 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0043 | 0.0031 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0687 | 0.0673 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0687 | 0.0619 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0283 | 0.0271 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0073 | 0.006 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.059 | 0.0521 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0879 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0094 | 0.0928 | 0.0916 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0247 | 0.2693 | 0.2669 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0164 | 0.0151 |
Plasmodium falciparum | pyruvate kinase | 0.0879 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0164 | 0.0151 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0928 | 0.0913 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0073 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0033 | 0.0018 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.2821 | 0.4039 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0164 | 0.0148 |
Onchocerca volvulus | 0.005 | 0.042 | 0.0382 | |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0065 | 0.059 | 0.0558 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0073 | 0.0687 | 0.0619 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0073 | 0.0033 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0061 | 0.0542 | 0.0527 |
Echinococcus multilocularis | pyruvate kinase | 0.0879 | 1 | 1 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0879 | 1 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0057 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0017 | 0.004 | 0.0028 |
Loa Loa (eye worm) | beta-lactamase | 0.0073 | 0.0687 | 0.0676 |
Echinococcus granulosus | cathepsin l1 | 0.0017 | 0.004 | 0.0007 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.01 | 0.0084 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0073 | 0.0687 | 0.0619 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0687 | 0.065 |
Loa Loa (eye worm) | ctsf protein | 0.0017 | 0.004 | 0.0028 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0073 | 0.004 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.0928 | 0.0897 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0016 | 0.0016 |
Brugia malayi | pyruvate kinase, muscle isozyme | 0.0185 | 0.1979 | 0.1969 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0017 | 0.004 | 0.0007 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.0531 | 0.0499 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.0255 | 0.0222 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.004 | 0.0028 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0073 | 0.0687 | 0.0619 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0687 | 0.0673 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0033 | 0.0021 |
Plasmodium vivax | pyruvate kinase, putative | 0.0879 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0033 | 0.0021 |
Loa Loa (eye worm) | pyruvate kinase | 0.0185 | 0.1979 | 0.1969 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0687 | 0.0676 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.004 | 0.0025 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0065 | 0.059 | 0.0575 |
Schistosoma mansoni | lamin | 0.0028 | 0.0164 | 0.0148 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0073 | 0.004 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.042 | 0.0406 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0073 | 0.0073 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0164 | 0.0151 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0057 |
Brugia malayi | pyruvate kinase | 0.0185 | 0.1979 | 0.1969 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0687 | 0.065 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0687 | 0.0676 |
Echinococcus granulosus | lamin | 0.0028 | 0.0164 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0073 | 0.006 |
Leishmania major | cathepsin L-like protease | 0.0017 | 0.004 | 0.0025 |
Onchocerca volvulus | 0.0073 | 0.0687 | 0.065 | |
Echinococcus multilocularis | pyruvate kinase | 0.0451 | 0.5054 | 0.5037 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0073 | 0.006 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0879 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.004 | 0.0028 |
Brugia malayi | Cathepsin L-like precursor | 0.0017 | 0.004 | 0.0028 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0073 | 0.004 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0073 | 0.0057 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.0036 | 0.0003 |
Onchocerca volvulus | 0.0028 | 0.0164 | 0.0124 | |
Loa Loa (eye worm) | pyruvate kinase | 0.0879 | 1 | 1 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0247 | 0.2693 | 0.2669 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0073 | 0.0687 | 0.0687 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Onchocerca volvulus | 0.0073 | 0.0687 | 0.065 | |
Schistosoma mansoni | lamin | 0.0028 | 0.0164 | 0.0148 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0608 | 0.0594 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.2821 | 0.4039 |
Brugia malayi | hypothetical protein | 0.0247 | 0.2693 | 0.2684 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0879 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0687 | 0.0676 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0077 | 0.0065 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0073 | 0.004 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0073 | 0.0057 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0879 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.2821 | 0.4039 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0017 | 0.004 | 0.0025 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.042 | 0.0408 |
Loa Loa (eye worm) | hypothetical protein | 0.0613 | 0.6925 | 0.6921 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0073 | 0.004 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0073 | 0.0073 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0073 | 0.0057 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.042 | 0.0406 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0073 | 0.0687 | 0.0619 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0164 | 0.0131 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0017 | 0.004 | 0.0007 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0282 | 0.027 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0164 | 0.0131 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0073 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0687 | 0.0676 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0077 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0033 | 0.0018 |
Entamoeba histolytica | hypothetical protein | 0.0258 | 0.2821 | 0.4039 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0613 | 0.6925 | 0.6921 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0687 | 0.0619 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0073 | 0.0687 | 0.0656 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0073 | 0.0073 |
Leishmania major | pyruvate kinase | 0.0879 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0608 | 0.0608 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0164 | 0.0131 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.0928 | 0.0897 |
Echinococcus granulosus | pyruvate kinase | 0.0451 | 0.5054 | 0.5037 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.059 | 0.0575 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0608 | 0.0594 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0073 | 0.0057 |
Echinococcus multilocularis | pyruvate kinase | 0.0451 | 0.5054 | 0.5037 |
Echinococcus multilocularis | geminin | 0.017 | 0.1804 | 0.1777 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.026 | 0.0248 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.1248 | 0.1237 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.026 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0687 | 0.0676 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0057 |
Plasmodium vivax | hypothetical protein, conserved | 0.0073 | 0.0687 | 0.065 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0073 | 0.006 |
Trichomonas vaginalis | esterase, putative | 0.0073 | 0.0687 | 0.065 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0073 | 0.0073 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0608 | 0.0594 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 100 ug ml-1 | Antifungal activity against candida albicans | ChEMBL. | 7629803 |
MIC (functional) | = 100 ug ml-1 | Antifungal activity against cryptococcus neoformans | ChEMBL. | 7629803 |
MIC (functional) | > 100 ug ml-1 | Antifungal activity against aspergillus fumigatus | ChEMBL. | 7629803 |
MIC (functional) | > 100 ug ml-1 | Antifungal activity against candida albicans | ChEMBL. | 7629803 |
MIC (functional) | = 100 ug ml-1 | Antifungal activity against cryptococcus neoformans | ChEMBL. | 7629803 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.