Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0406 | 0.6467 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0141 | 0.1393 | 0.2154 |
Echinococcus granulosus | acetylcholinesterase | 0.0406 | 0.6467 | 1 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0141 | 0.1393 | 0.2154 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0069 | 0 | 0.5 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0119 | 0.0961 | 0.1486 |
Loa Loa (eye worm) | hypothetical protein | 0.0406 | 0.6467 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0119 | 0.0961 | 0.1486 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0097 | 0.0551 | 0.0851 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0336 | 0.5135 | 0.794 |
Echinococcus granulosus | glutamate receptor 2 | 0.0141 | 0.1393 | 0.2154 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0141 | 0.1393 | 0.2154 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0406 | 0.6467 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0406 | 0.6467 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0406 | 0.6467 | 1 |
Onchocerca volvulus | 0.0069 | 0 | 0.5 | |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0119 | 0.0961 | 0.1486 |
Echinococcus multilocularis | acetylcholinesterase | 0.0406 | 0.6467 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0406 | 0.6467 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0406 | 0.6467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0406 | 0.6467 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0119 | 0.0961 | 0.1486 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0069 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0548 | 0.9203 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0406 | 0.6467 | 1 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0119 | 0.0961 | 0.1486 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0119 | 0.0961 | 0.1486 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0199 | 0.2509 | 0.3879 |
Onchocerca volvulus | 0.0069 | 0 | 0.5 | |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0178 | 0.2098 | 0.3244 |
Onchocerca volvulus | 0.0069 | 0 | 0.5 | |
Schistosoma mansoni | glutamate receptor kainate | 0.0119 | 0.0961 | 0.1486 |
Onchocerca volvulus | 0.0069 | 0 | 0.5 | |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0141 | 0.1393 | 0.2154 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0155 | 0.1666 | 0.2577 |
Brugia malayi | Carboxylesterase family protein | 0.0406 | 0.6467 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0141 | 0.1393 | 0.2154 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0141 | 0.1393 | 0.2154 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.059 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0406 | 0.6467 | 1 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0119 | 0.0961 | 0.1486 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0141 | 0.1393 | 0.2154 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0119 | 0.0961 | 0.1486 |
Schistosoma mansoni | glutamate receptor kainate | 0.0119 | 0.0961 | 0.1486 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0119 | 0.0961 | 0.1486 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0199 | 0.2509 | 0.3879 |
Onchocerca volvulus | 0.0069 | 0 | 0.5 | |
Schistosoma mansoni | glutamate receptor NMDA | 0.0336 | 0.5135 | 0.794 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0297 | 0.4374 | 0.6764 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0141 | 0.1393 | 0.2154 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0178 | 0.2098 | 0.3244 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0141 | 0.1393 | 0.2154 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0336 | 0.5135 | 0.794 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0155 | 0.1666 | 0.2577 |
Echinococcus granulosus | glutamate receptor 2 | 0.0097 | 0.0551 | 0.0851 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.