Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | checkpoint kinase 1 | Starlite/ChEMBL | References |
Homo sapiens | checkpoint kinase 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0045 | 0 | 0.5 | |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0045 | 0 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0045 | 0 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0202 | 0.7024 | 0.7024 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0045 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0202 | 0.7024 | 0.7024 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase Chk2 | 0.0046 | 0.0044 | 0.0044 |
Onchocerca volvulus | 0.0045 | 0 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0046 | 0.0044 | 0.5 |
Echinococcus multilocularis | calcium:calmodulin dependent protein kinase I | 0.0046 | 0.0043 | 0.0043 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0046 | 0.0044 | 0.0044 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase I | 0.0046 | 0.0043 | 0.0043 |
Onchocerca volvulus | 0.0045 | 0 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0269 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0045 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0269 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0269 | 1 | 1 |
Onchocerca volvulus | 0.0045 | 0 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0045 | 0 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0046 | 0.0044 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0269 | 1 | 1 |
Loa Loa (eye worm) | CAMK/CAMKL/CHK1 protein kinase | 0.0202 | 0.7024 | 0.7024 |
Onchocerca volvulus | 0.0045 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0269 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0269 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0269 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0269 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0269 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0269 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase Chk2 | 0.0046 | 0.0044 | 0.0044 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.