Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.3298 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Leishmania major | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.003 | 0.1553 | 0.471 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.3298 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0021 | 0 | 0.5 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0035 | 0.2563 | 0.2563 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Trypanosoma cruzi | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Echinococcus multilocularis | ectonucleotide | 0.003 | 0.1553 | 0.471 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2563 | 0.1195 |
Trypanosoma brucei | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.3298 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 1 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Trypanosoma brucei | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.3298 | 0.3298 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.3298 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2563 | 0.1195 |
Onchocerca volvulus | 0.0076 | 1 | 1 | |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.3298 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.3298 | 0.3298 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.3298 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.003 | 0.1553 | 0.471 |
Brugia malayi | hypothetical protein | 0.0039 | 0.3298 | 0.3298 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2563 | 0.1195 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 0.7771 |
Echinococcus granulosus | ectonucleotide | 0.003 | 0.1553 | 0.471 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.