Detailed information for compound 149304

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 345.441 | Formula: C21H23N5
  • H donors: 1 H acceptors: 3 LogP: 4.11 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1CCN(CC1)c1ccc(cc1)Nc1nccc(n1)c1ccccn1
  • InChi: 1S/C21H23N5/c1-16-10-14-26(15-11-16)18-7-5-17(6-8-18)24-21-23-13-9-20(25-21)19-4-2-3-12-22-19/h2-9,12-13,16H,10-11,14-15H2,1H3,(H,23,24,25)
  • InChiKey: YHGHLCWMCKNIEC-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Plasmodium vivax serine-repeat antigen (SERA) 0.0049 0.0029 0.0182
Entamoeba histolytica cysteine proteinase, putative 0.0124 0.0487 0.3193
Brugia malayi calpain family protein 1 0.0284 0.1455 0.4236
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0286 0.1468 0.3013
Schistosoma mansoni protease m14 carboxypeptidase 0.0121 0.047 0.1365
Mycobacterium ulcerans haloalkane dehalogenase 0.0046 0.0016 0.0016
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0477 0.263 0.5397
Leishmania major trypanothione synthetase, putative 0.0069 0.0154 0.0284
Brugia malayi calpain family protein 1 0.0284 0.1455 0.4236
Plasmodium vivax serine-repeat antigen (SERA) 0.0049 0.0029 0.0182
Trypanosoma cruzi kinesin, putative 0.0059 0.0093 0.0191
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4604 0.9447
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.0121 0.047 0.0964
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0055 0.0138
Leishmania major hypothetical protein, conserved 0.0069 0.0154 0.0284
Leishmania major small myristoylated protein-2 0.073 0.416 0.8532
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Leishmania major hypothetical protein, conserved 0.0275 0.1405 0.286
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Leishmania major META domain containing protein 0.0275 0.1405 0.286
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0477 0.263 0.5397
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0847 0.4873 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.006 0.0096 0.0255
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0577 0.3235 0.6639
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0045 0.0008 0.0022
Entamoeba histolytica cysteine protease, putative 0.0049 0.0029 0.0188
Echinococcus multilocularis hypothetical protein 0.0284 0.1455 0.3067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Mycobacterium tuberculosis Possible haloalkane dehalogenase DhaA (1-chlorohexane halidohydrolase) 0.0046 0.0016 0.0016
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Echinococcus granulosus calpain 0.0284 0.1455 0.4227
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0284 0.1455 0.4227
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Plasmodium vivax vivapain-1 0.0124 0.0487 0.309
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.1196 0.3473
Toxoplasma gondii kringle domain-containing protein 0.0091 0.0284 0.0801
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0352 0.187 0.3837
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0075 0.0188 0.0545
Echinococcus granulosus tm gpcr rhodopsin 0.0521 0.2892 0.8398
Onchocerca volvulus 0.0053 0.0055 0.0161
Entamoeba histolytica cysteine proteinase, putative 0.0124 0.0487 0.3193
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0049 0.0029 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0029 0.0158
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.008 0.022 0.0638
Trichomonas vaginalis conserved hypothetical protein 0.0343 0.1817 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Loa Loa (eye worm) hypothetical protein 0.049 0.2708 0.7881
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0135 0.0555 0.3054
Onchocerca volvulus Lipase homolog 0.0046 0.0016 0.0047
Echinococcus multilocularis calpain A 0.0284 0.1455 0.3067
Trypanosoma brucei Calpain-like protein 2 0.0629 0.355 0.7286
Echinococcus granulosus Zinc carboxypeptidase family protein 0.0121 0.047 0.1365
Schistosoma mansoni peptidase 0.0121 0.047 0.1365
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.008 0.022 0.4676
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0116 0.0437 0.1269
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0027 0.018
Toxoplasma gondii homoserine O-acetyltransferase, putative 0.0046 0.0016 0.0025
Toxoplasma gondii PAN domain-containing protein 0.0614 0.3456 1
Toxoplasma gondii flagellar/basal body protein 0.0121 0.047 0.1341
Onchocerca volvulus 0.0235 0.1159 0.3366
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0513
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.345
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0073 0.0176 0.375
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Mycobacterium ulcerans epoxide hydrolase EphA 0.1693 1 1
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0275 0.1405 0.2884
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0235 0.1159 0.9525
Onchocerca volvulus 0.0116 0.0438 0.1271
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0128 0.0512 0.2816
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0107 0.038 0.0781
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0027 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0126 0.0365
Leishmania major cathepsin L-like protease 0.0235 0.1159 0.2353
Giardia lamblia Cathepsin L precursor 0.0049 0.0029 0.0611
Toxoplasma gondii hypothetical protein 0.0225 0.1097 0.3158
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0418 0.2271 0.4643
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0084 0.0246 0.1353
Leishmania major small myristoylated protein-3, putative 0.0373 0.1998 0.4081
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0235 0.1159 0.3373
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0233 0.0479
Loa Loa (eye worm) hypothetical protein 0.005 0.0035 0.0102
Entamoeba histolytica cysteine protease, putative 0.0049 0.0029 0.0188
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0055 0.0161
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0217 0.1049 0.2152
Schistosoma mansoni cathepsin F (C01 family) 0.0159 0.0701 0.2035
Brugia malayi Zinc carboxypeptidase family protein 0.0121 0.047 0.1368
Leishmania major hypothetical protein, unknown function 0.0679 0.3852 0.7897
Mycobacterium tuberculosis Probable exported protease 0.0046 0.0016 0.0016
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.345
Echinococcus multilocularis cysteine protease atg4b 0.0084 0.0246 0.0518
Echinococcus granulosus Peptidase C54 0.0084 0.0246 0.0714
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Giardia lamblia Cathepsin L precursor 0.0049 0.0029 0.0611
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Echinococcus granulosus cysteine protease atg4b 0.0084 0.0246 0.0714
Mycobacterium ulcerans hypothetical protein 0.0048 0.0027 0.0027
Schistosoma mansoni autophagin-1 (C54 family) 0.0084 0.0246 0.0714
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0045 0.0008 0.0022
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0269 0.1363 0.2798
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0584 0.3277 0.6725
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0084 0.0246 0.1353
Onchocerca volvulus 0.0053 0.0055 0.0161
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0037 0.0201
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0045 0.0008 0.0022
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0112 0.0414 0.1203
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.0284 0.0582
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0135 0.0555 0.3054
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0266 0.1348 0.2742
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0275 0.1405 0.2884
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.0116 0.0437 0.1271
Loa Loa (eye worm) hypothetical protein 0.0117 0.0447 0.1301
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0217 0.1049 0.2126
Loa Loa (eye worm) hypothetical protein 0.0076 0.0193 0.0561
Loa Loa (eye worm) hypothetical protein 0.0076 0.0193 0.0561
Giardia lamblia Cysteine protease 0.0049 0.0029 0.0611
Mycobacterium ulcerans proline iminopeptidase PIP 0.0046 0.0016 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0373 0.1998 0.4101
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0045 0.0008 0.0022
Mycobacterium ulcerans bromoperoxidase BpoC 0.0046 0.0016 0.0016
Toxoplasma gondii preprocathepsin c precursor, putative 0.0049 0.0029 0.0061
Mycobacterium tuberculosis Possible haloalkane dehalogenase 0.0046 0.0016 0.0016
Brugia malayi Zinc carboxypeptidase family protein 0.0121 0.047 0.1368
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0047 0.0021 0.004
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.016 0.0706 0.145
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0225 0.1097 0.6037
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0084 0.0246 0.0504
Chlamydia trachomatis phosphoglycolate phosphatase 0.0044 0 0.5
Mycobacterium ulcerans 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase BphD 0.0046 0.0016 0.0016
Mycobacterium ulcerans exported protease 0.0046 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Schistosoma mansoni hypothetical protein 0.0225 0.1097 0.3185
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0029 0.0158
Onchocerca volvulus 0.0121 0.047 0.1365
Toxoplasma gondii cathepsin CPL 0.0235 0.1159 0.3338
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0107 0.038 0.1107
Trypanosoma brucei small myristoylated protein 1-2 0.0429 0.2337 0.4796
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0066 0.0136 0.0395
Plasmodium vivax vivapain-2 0.0235 0.1159 0.7356
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0161
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0029 0.0084
Loa Loa (eye worm) ab-hydrolase associated lipase region family protein 0.0046 0.0016 0.0047
Echinococcus granulosus cathepsin l1 0.0235 0.1159 0.3366
Onchocerca volvulus 0.0045 0.0008 0.0022
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.05 0.2767 0.5679
Brugia malayi Angiotensin-converting enzyme family protein 0.061 0.3436 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.006 0.0096 0.0527
Brugia malayi Papain family cysteine protease containing protein 0.0124 0.0487 0.1417
Leishmania major calpain protease-like protein 0.0257 0.1294 0.2632
Toxoplasma gondii peptidase c13 family protein 0.0063 0.0115 0.031
Onchocerca volvulus 0.0235 0.1159 0.3366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Echinococcus multilocularis Ubiquitin thioesterase otubain protein 0.0088 0.027 0.0568
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0239 0.1182 0.2426
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0029 0.0611
Mycobacterium ulcerans epoxide hydrolase EphE 0.0046 0.0016 0.0016
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0084 0.0246 0.0473
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0037 0.0201
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0304 0.1575 0.3233
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0046 0.0016 0.0033
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0079 0.0216 0.1371
Onchocerca volvulus 0.0159 0.0701 0.2035
Leishmania major hypothetical protein, conserved 0.0446 0.2437 0.4985
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0045 0.0008 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0225 0.1097 0.6037
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0075 0.0188 0.0395
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0112 0.0414 0.085
Schistosoma mansoni cathepsin F (C01 family) 0.0235 0.1159 0.3366
Mycobacterium ulcerans exported protease 0.0046 0.0016 0.0016
Trypanosoma cruzi hydrolase, alpha/beta fold family, putative 0.0046 0.0016 0.0033
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.005 0.0037 0.03
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0239 0.1182 0.2426
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Trypanosoma brucei SUMO1/Ulp2, putative 0.0185 0.0856 0.1757
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0066 0.0136 0.0279
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0235 0.1159 0.2442
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0084 0.0246 0.1353
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0161
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Leishmania major cathepsin L-like protease 0.0235 0.1159 0.2353
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0128 0.0512 0.2816
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0082 0.0233 0.0492
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0128 0.0512 0.1486
Onchocerca volvulus 0.0611 0.3443 1
Treponema pallidum phosphoglycolate phosphatase 0.0044 0 0.5
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0082 0.0233 0.0447
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus calpain A 0.0284 0.1455 0.4227
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0154 0.0317
Loa Loa (eye worm) hypothetical protein 0.0049 0.0029 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.008 0.022 0.121
Loa Loa (eye worm) zinc carboxypeptidase 0.0121 0.047 0.1368
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Echinococcus granulosus cysteine protease 0.0124 0.0487 0.1414
Plasmodium falciparum serine repeat antigen 5 0.0049 0.0029 0.0236
Trypanosoma cruzi cysteine peptidase, putative 0.0428 0.2328 0.4777
Mycobacterium tuberculosis Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA) 0.0046 0.0016 0.0016
Entamoeba histolytica calpain family cysteine protease, putative 0.0295 0.1525 1
Mycobacterium tuberculosis Possible peroxidase BpoB (non-haem peroxidase) 0.0046 0.0016 0.0016
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0671 0.3802 0.7795
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0269 0.1363 0.2798
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Trichomonas vaginalis carboxypeptidase regulatory region-containing protein, putative 0.0052 0.0051 0.0282
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0029 0.0158
Trypanosoma cruzi trypanothione synthetase 0.0069 0.0154 0.0317
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0049 0.0029 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0487 0.268
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus calpain 7 C02 family 0.0316 0.1653 0.4801
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0066 0.0136 0.0396
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.008 0.022 0.0463
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0055 0.0161
Echinococcus multilocularis cathepsin b 0.0112 0.0414 0.0873
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0269 0.1363 0.2798
Entamoeba histolytica cysteine protease, putative 0.0049 0.0029 0.0188
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0116 0.0437 0.1269
Echinococcus multilocularis calpain family protein 1, d 0.0225 0.1097 0.2311
Mycobacterium tuberculosis Conserved protein 0.0046 0.0016 0.0016
Trypanosoma brucei calpain, putative 0.0493 0.2726 0.5594
Plasmodium falciparum plasmepsin II 0.0117 0.0447 0.3673
Loa Loa (eye worm) fibroinase 0.0235 0.1159 0.3373
Schistosoma mansoni cathepsin B (C01 family) 0.0049 0.0029 0.0083
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Brugia malayi cathepsin B-like cysteine proteinase 0.0112 0.0414 0.1206
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.005 0.0037 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0373 0.1998 0.4101
Trichomonas vaginalis calpain, putative 0.0225 0.1097 0.6037
Giardia lamblia Cathepsin B precursor 0.0049 0.0029 0.0611
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0126 0.0265
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Trypanosoma cruzi hydrolase-like protein, putative 0.0046 0.0016 0.0033
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Entamoeba histolytica cysteine protease inhibitor 1 (EhICP1) 0.024 0.1193 0.7821
Onchocerca volvulus 0.0611 0.3443 1
Brugia malayi Hypothetical 54.7 kDa protein F37A4.1 in chromosome III 0.0046 0.0016 0.0047
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.0063 0.0118 0.0344
Mycobacterium leprae Probable homoserine o-acetyltransferase MetA 0.0046 0.0016 0.4043
Schistosoma mansoni peptidase 0.0121 0.047 0.1365
Toxoplasma gondii microneme protein MIC4 0.0053 0.0055 0.0138
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0045 0.0008 0.0022
Echinococcus multilocularis cathepsin b 0.0112 0.0414 0.0873
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0029 0.0083
Trypanosoma cruzi ubiquitin hydrolase, putative 0.016 0.0706 0.145
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0016 0.0103
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.0442 0.2415 0.4956
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0117 0.0447 0.1298
Onchocerca volvulus Lipase homolog 0.0046 0.0016 0.0047
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0091 0.0284 0.1801
Trypanosoma brucei amidase, putative 0.0069 0.0154 0.0317
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Trypanosoma brucei Calpain-like protein 1.1 0.0847 0.4873 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0193 0.0561
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.1998 0.4101
Giardia lamblia Cathepsin L-like protease 0.0049 0.0029 0.0611
Plasmodium vivax plasmepsin IV, putative 0.0117 0.0447 0.2836
Trypanosoma cruzi kinesin, putative 0.0059 0.0093 0.0191
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0275 0.1405 0.2884
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0045 0.0008 0.0022
Giardia lamblia Cathepsin B precursor 0.0049 0.0029 0.0611
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0493 0.2726 0.5594
Loa Loa (eye worm) hypothetical protein 0.0235 0.1159 0.3373
Trypanosoma cruzi cysteine protease, putative 0.0124 0.0487 0.0999
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Brugia malayi TAR-binding protein 0.0065 0.0126 0.0366
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0116 0.0437 0.092
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Leishmania major trypanothione synthetase-like protein 0.0069 0.0154 0.0284
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0185 0.0856 0.1757
Plasmodium falciparum plasmepsin VI 0.0117 0.0447 0.3673
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0029 0.0158
Entamoeba histolytica cysteine protease inhibitor 2 (EhICP2) 0.024 0.1193 0.7821
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0046 0.0016 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0128 0.0512 0.1486
Echinococcus multilocularis cathepsin L cysteine protease 0.0235 0.1159 0.2442
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0082 0.0233 0.153
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0045 0.0008 0.0016
Trypanosoma brucei unspecified product 0.0275 0.1405 0.2884
Echinococcus multilocularis ubiquitin specific protease 41 0.008 0.022 0.0463
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Schistosoma mansoni hydrolase 0.0046 0.0016 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Leishmania major hypothetical protein, conserved 0.0275 0.1405 0.286
Echinococcus granulosus cathepsin b 0.0112 0.0414 0.1203
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0055 0.0138
Echinococcus multilocularis GPI anchor transamidase 0.0063 0.0115 0.0242
Echinococcus granulosus tar DNA binding protein 0.0065 0.0126 0.0365
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0029 0.0084
Trypanosoma cruzi cysteine proteinase, putative 0.0124 0.0487 0.0999
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0063 0.0115 0.0235
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0826 0.4745 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.0438 0.1274
Mycobacterium ulcerans lipase/esterase 0.0046 0.0016 0.0016
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0354 0.188 0.3857
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Trypanosoma cruzi conserved protein 0.0446 0.2437 0.5001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0235 0.1159 0.6379
Echinococcus multilocularis 0.0121 0.047 0.099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trypanosoma brucei calpain-like protein, putative 0.0284 0.1455 0.2987
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0088 0.027 0.0553
Giardia lamblia Cathepsin B precursor 0.0112 0.0414 0.8814
Trypanosoma cruzi cysteine peptidase, putative 0.0428 0.2328 0.4777
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0266 0.1348 0.2766
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0102 0.035 0.0688
Brugia malayi hypothetical protein 0.0241 0.1196 0.348
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.005 0.0037 0.0077
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0049 0.0029 0.0182
Plasmodium falciparum serine repeat antigen 3 0.0049 0.0029 0.0236
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0142 0.0781
Trypanosoma cruzi small myristoylated protein 1-2 0.0429 0.2337 0.4796
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Trypanosoma cruzi Carboxypeptidase-like protein 0.0121 0.047 0.0964
Trypanosoma brucei otubain cysteine peptidase, Clan CA, family C65, putative 0.0088 0.027 0.0553
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0029 0.0083
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Mycobacterium tuberculosis Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase) 0.0046 0.0016 0.0016
Schistosoma mansoni cathepsin F (C01 family) 0.0235 0.1159 0.3366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0027 0.0027
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0066 0.0136 0.0279
Echinococcus granulosus cathepsin L 0.0124 0.0487 0.1414
Loa Loa (eye worm) RNA binding protein 0.0065 0.0126 0.0366
Trypanosoma cruzi cysteine peptidase inhibitor, putative 0.024 0.1193 0.2447
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0008 0.0049
Brugia malayi cathepsin Z-like cysteine proteinase 0.0049 0.0029 0.0084
Loa Loa (eye worm) abhydrolase domain-containing protein 2 0.0046 0.0016 0.0047
Leishmania major trypanothione synthetase, putative 0.0069 0.0154 0.0284
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0128 0.0512 0.1461
Trypanosoma cruzi hypothetical protein, conserved 0.0275 0.1405 0.2884
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0102 0.035 0.0738
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0102 0.035 0.1929
Onchocerca volvulus Cathepsin F homolog 0.0235 0.1159 0.3366
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0128 0.0512 0.102
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0027 0.0027
Leishmania major inhibitor of cysteine peptidase 0.024 0.1193 0.2422
Brugia malayi alpha/beta hydrolase 0.0046 0.0016 0.0047
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0066 0.0136 0.0892
Giardia lamblia Cathepsin B precursor 0.0049 0.0029 0.0611
Toxoplasma gondii cathepsin CPC1 0.0049 0.0029 0.0061
Mycobacterium ulcerans hydrolase 0.0046 0.0016 0.0016
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14 0.0121 0.047 0.0964
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Brugia malayi Cathepsin L-like precursor 0.0159 0.0701 0.204
Loa Loa (eye worm) hypothetical protein 0.0284 0.1455 0.4236
Trypanosoma brucei hypothetical protein 0.0493 0.2726 0.5594
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0045 0.0008 0.0042
Trypanosoma brucei hypothetical protein, conserved 0.0343 0.1817 0.3728
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0354 0.188 0.3857
Toxoplasma gondii PAN domain-containing protein 0.0614 0.3456 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0239 0.1182 0.2426
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0418 0.2271 0.4643
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0049 0.0029 0.0182
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0623 0.3511 0.7204
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0066 0.0136 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0029 0.0158
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0217 0.1049 0.2152
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0107 0.038 0.0781
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.008 0.022 0.1441
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus multilocularis tumor protein p63 0.0344 0.1822 0.384
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0142 0.0781
Toxoplasma gondii microneme protein MIC17C 0.0053 0.0055 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0124 0.0487 0.268
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0235 0.1159 0.2442
Plasmodium falciparum plasmepsin IV 0.0117 0.0447 0.3673
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0075 0.0188 0.0545
Onchocerca volvulus 0.0053 0.0055 0.0161
Trypanosoma brucei Calpain-like protein CALP1.3 0.05 0.2767 0.5679
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0049 0.0029 0.0188
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Onchocerca volvulus 0.0235 0.1159 0.3366
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0121 0.047 0.0934
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0046 0.0016 0.0034
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0161
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0121 0.047 0.0934
Entamoeba histolytica hypothetical protein 0.0063 0.0118 0.0776
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0671 0.3802 0.7802
Mycobacterium leprae Probable exported protease 0.0046 0.0016 0.4043
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0176 0.0362
Entamoeba histolytica alpha/beta hydrolase domain protein, putative 0.0046 0.0016 0.0106
Trypanosoma cruzi trypanothione synthetase, putative 0.0069 0.0154 0.0317
Leishmania major hypothetical protein, conserved 0.0343 0.1817 0.3707
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0112 0.0414 0.1203
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0128 0.0512 0.105
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0671 0.3802 0.7802
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0084 0.0246 0.0714
Giardia lamblia Cysteine protease 0.0049 0.0029 0.0611
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0079 0.0216 0.4594
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.0063 0.0118 0.0249
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Loa Loa (eye worm) calpain 0.0316 0.1653 0.4812
Schistosoma mansoni cellular tumor antigen P53 0.005 0.004 0.0116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Schistosoma mansoni otubain-1 (C65 family) 0.0088 0.027 0.0783
Leishmania major kinesin, putative 0.0059 0.0093 0.0158
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0079 0.0216 0.0455
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.008 0.022 0.0638
Loa Loa (eye worm) hypothetical protein 0.0112 0.0414 0.1206
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0284 0.1455 0.4227
Onchocerca volvulus Cytosolic carboxypeptidase 1 homolog 0.0121 0.047 0.1365
Schistosoma mansoni carboxypeptidase N (M14 family) 0.0121 0.047 0.1365
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0121 0.047 1
Echinococcus granulosus cytosolic carboxypeptidase protein 5 0.0121 0.047 0.1365
Trypanosoma brucei Calpain-like protein 1.2 0.0647 0.3661 0.7513
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0135 0.0555 0.3638
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0116 0.0437 0.0896
Trypanosoma brucei calpain, putative 0.0225 0.1097 0.2251
Loa Loa (eye worm) hypothetical protein 0.0049 0.0029 0.0084
Leishmania major cathepsin L-like protease 0.0235 0.1159 0.2353
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0066 0.0136 0.1118
Loa Loa (eye worm) hydrolase 0.0046 0.0016 0.0047
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0552 0.3085 0.633
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0124 0.0487 0.1414
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0046 0.0016 0.0089
Plasmodium falciparum alpha/beta hydrolase, putative 0.0046 0.0016 0.0133
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0075 0.0188 0.0353
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0847 0.4873 1
Plasmodium vivax aspartyl proteinase, putative 0.0117 0.0447 0.2836
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0185 0.0856 0.1757
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0077 0.0204 0.0419
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0577 0.3235 0.6627
Trypanosoma cruzi trypanothione synthetase-like protein, putative 0.0069 0.0154 0.0317
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0171 0.0769 0.1578
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0035 0.0102
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.005 0.0037 0.0106
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0107 0.038 0.1105
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0073 0.0176 0.033
Plasmodium vivax ubiquitin specific protease, putative 0.0045 0.0008 0.0049
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0615 0.3462 0.7094
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0135 0.0555 0.1169
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0073 0.0176 0.097
Schistosoma mansoni cathepsin S (C01 family) 0.0049 0.0029 0.0083
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0188 0.0385
Brugia malayi Zinc carboxypeptidase family protein 0.0121 0.047 0.1368
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0027 0.018
Echinococcus multilocularis abhydrolase domain containing protein 11 0.0046 0.0016 0.0034
Entamoeba histolytica peptidase, C54 family 0.0084 0.0246 0.1612
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0045 0.0008 0.0016
Loa Loa (eye worm) zinc carboxypeptidase 0.0121 0.047 0.1368
Brugia malayi Protein kinase domain containing protein 0.0091 0.0284 0.0826
Echinococcus granulosus Ubiquitin thioesterase otubain protein 0.0088 0.027 0.0783
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0045 0.0008 0.0022
Brugia malayi Cathepsin L-like cysteine proteinase 0.0159 0.0701 0.204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Schistosoma mansoni subfamily M14A unassigned peptidase (M14 family) 0.0611 0.3443 1
Leishmania major cathepsin L-like protease 0.0428 0.2328 0.476
Trichomonas vaginalis calpain, putative 0.0225 0.1097 0.6037
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0126 0.0365
Brugia malayi Cathepsin L-like precursor 0.0235 0.1159 0.3373
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0121 0.047 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Plasmodium falciparum serine repeat antigen 4 0.0049 0.0029 0.0236
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.008 0.022 0.0451
Trypanosoma cruzi trypanothione synthetase, putative 0.0069 0.0154 0.0317
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0045 0.0008 0.0042
Schistosoma mansoni Mername-AA248 (C02 family) 0.0284 0.1455 0.4227
Schistosoma mansoni metallocarboxypeptidase D peptidase unit 2 (M14 family) 0.0121 0.047 0.1365
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0055 0.0138
Brugia malayi Cathepsin L-like precursor 0.0235 0.1159 0.3373
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus calpain 5 0.0284 0.1455 0.4227
Trypanosoma brucei CHAP domain containing protein, putative 0.0069 0.0154 0.0317
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.0121 0.047 0.1341
Brugia malayi Zinc carboxypeptidase family protein 0.0121 0.047 0.1368
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0284 0.1455 0.4227
Entamoeba histolytica cysteine proteinase, putative 0.0235 0.1159 0.76
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0084 0.0246 0.1353
Leishmania major hypothetical protein, conserved 0.0275 0.1405 0.286
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0049 0.0029 0.0182
Leishmania major hypothetical protein, conserved 0.0275 0.1405 0.286
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Toxoplasma gondii microneme protein MIC17A 0.0053 0.0055 0.0138
Loa Loa (eye worm) hypothetical protein 0.0091 0.0284 0.0826
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0046 0.0016 0.0089
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0615 0.3462 0.7104
Echinococcus multilocularis cathepsin L 0.0049 0.0029 0.006
Brugia malayi hydrolase, alpha/beta fold family protein 0.0046 0.0016 0.0047
Trypanosoma cruzi cruzipain precursor, putative 0.0428 0.2328 0.4777
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0046 0.0016 0.0089
Loa Loa (eye worm) hypothetical protein 0.0174 0.0787 0.229
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0552 0.3085 0.633
Toxoplasma gondii cathepsin B 0.0112 0.0414 0.1179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0107 0.038 0.1107
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Trypanosoma brucei cysteine peptidase C (CPC) 0.0112 0.0414 0.085
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0008 0.005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0073 0.0176 0.0371
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0075 0.0188 0.0546
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0235 0.1159 0.3373
Plasmodium vivax hypothetical protein, conserved 0.0066 0.0136 0.0863
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0045 0.0008 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0275 0.1405 0.2884
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0286 0.1468 0.3013
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0552 0.3085 0.633
Giardia lamblia Cathepsin L precursor 0.0049 0.0029 0.0611
Brugia malayi hypothetical protein 0.0045 0.0008 0.0022
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0035 0.0102
Mycobacterium ulcerans oxidoreductase 0.0046 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Echinococcus granulosus abhydrolase domain containing protein 0.0046 0.0016 0.0047
Echinococcus granulosus tumor protein p63 0.0344 0.1822 0.5293
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.005 0.0037 0.0106
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0225 0.1097 0.2251
Loa Loa (eye worm) hypothetical protein 0.0159 0.0701 0.204
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0239 0.1182 0.2401
Onchocerca volvulus Carboxypeptidase D homolog 0.0174 0.0787 0.2285
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.005 0.0037 0.0106
Echinococcus granulosus ubiquitin specific protease 41 0.008 0.022 0.0638
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.3428
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Toxoplasma gondii ubiquitin thioesterase otubain-like family protein 0.0088 0.027 0.0759
Onchocerca volvulus Cathepsin L homolog 0.0235 0.1159 0.3366
Leishmania major cathepsin L-like protease 0.0428 0.2328 0.476
Onchocerca volvulus 0.0048 0.0027 0.008
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0176 0.1119
Loa Loa (eye worm) hypothetical protein 0.0225 0.1097 0.3192
Onchocerca volvulus 0.0053 0.0055 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0049 0.0029 0.0158
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0584 0.3277 0.6725
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Brugia malayi cathepsin L-like cysteine proteinase 0.0049 0.0029 0.0084
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0413 0.2238 0.4576
Schistosoma mansoni calpain-7 (C02 family) 0.0361 0.1926 0.5595
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0055 0.0161
Trichomonas vaginalis hydrolase, putative 0.0046 0.0016 0.0089
Brugia malayi calpain 5 0.0225 0.1097 0.3192
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0176 0.0362
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0073 0.0176 0.0512
Plasmodium falciparum cysteine repeat modular protein 1 0.0091 0.0284 0.2332
Loa Loa (eye worm) calpain D 0.0295 0.1525 0.4438
Loa Loa (eye worm) hypothetical protein 0.0048 0.0027 0.008
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0102 0.035 0.0719
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0107 0.038 0.0802
Toxoplasma gondii hypothetical protein 0.0053 0.0055 0.0138
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0116 0.0437 0.1269
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.345
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0112 0.0414 0.085
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0045 0.0008 0.0022
Brugia malayi cathepsin F-like cysteine proteinase 0.0076 0.0193 0.0561
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.005 0.004 0.004
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0045 0.0008 0.0022
Mycobacterium ulcerans lipase/esterase 0.0046 0.0016 0.0016
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0126 0.0366
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0027 0.018
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Mycobacterium ulcerans epoxide hydrolase EphB 0.0046 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0029 0.0158
Mycobacterium tuberculosis Possible epoxide hydrolase EphE (epoxide hydratase) (arene-oxide hydratase) 0.0046 0.0016 0.0016
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0045 0.0008 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Trypanosoma brucei Carboxypeptidase-like protein 0.0121 0.047 0.0964
Entamoeba histolytica hypothetical protein 0.0045 0.0008 0.005
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4604 0.9447
Plasmodium vivax alpha/beta hydrolase, putative 0.0046 0.0016 0.0103
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.008 0.022 0.121
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0046 0.0016 0.0089
Onchocerca volvulus 0.0611 0.3443 1
Trichomonas vaginalis conserved hypothetical protein 0.0225 0.1097 0.6037
Loa Loa (eye worm) hypothetical protein 0.008 0.022 0.064
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0035 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0135 0.0555 0.1138
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0647 0.3661 0.7513
Plasmodium vivax calpain, putative 0.0304 0.1575 1
Brugia malayi Papain family cysteine protease containing protein 0.0235 0.1159 0.3373
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0266 0.1348 0.2742
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0201 0.0953 0.193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0225 0.1097 0.6037
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0304 0.1575 0.3233
Echinococcus multilocularis cytosolic carboxypeptidase protein 5 0.0121 0.047 0.099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0063 0.0115 0.0333
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0126 0.0365
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0045 0.0008 0.0016
Toxoplasma gondii exonuclease 0.0062 0.0113 0.0305
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.345
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0049 0.0029 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0049 0.0029 0.0158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Echinococcus multilocularis geminin 0.0171 0.0772 0.1628
Leishmania major cathepsin L-like protease 0.0235 0.1159 0.2353
Mycobacterium tuberculosis Probable carboxylesterase CaeA 0.0046 0.0016 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0016 0.0033
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0239 0.1182 0.2426
Entamoeba histolytica cysteine protease, putative 0.0235 0.1159 0.76
Brugia malayi hydrolase, alpha/beta fold family protein 0.0046 0.0016 0.0047
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.008 0.022 0.0638
Entamoeba histolytica cysteine protease, putative 0.0049 0.0029 0.0188
Echinococcus granulosus cathepsin L cysteine protease 0.0124 0.0487 0.1414
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Brugia malayi cathepsin Z-like cysteine proteinase 0.0049 0.0029 0.0084
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0076 0.0193 0.0561
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.005 0.0037 0.0106
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0116 0.0437 0.0896
Schistosoma mansoni peptidase 0.0121 0.047 0.1365
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0029 0.0611
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0552 0.3085 0.6318
Loa Loa (eye worm) hypothetical protein 0.0159 0.0701 0.204
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.0063 0.0118 0.0344
Giardia lamblia Cathepsin B precursor 0.0112 0.0414 0.8814
Brugia malayi calpain 5 0.0059 0.0093 0.0271
Loa Loa (eye worm) hypothetical protein 0.0084 0.0246 0.0715
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis calpain, putative 0.0225 0.1097 0.6037
Trypanosoma cruzi cysteine peptidase, putative 0.0235 0.1159 0.2378
Brugia malayi Kringle domain containing protein 0.0091 0.0284 0.0826
Schistosoma mansoni hypothetical protein 0.0171 0.0772 0.2243
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0126 0.0366
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0027 0.6836
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0063 0.0115 0.0203
Echinococcus multilocularis Peptidase C54 0.0084 0.0246 0.0518
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0045 0.0008 0.0022
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0073 0.0176 0.0489
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0487 0.0999
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0082 0.023 0.146
Plasmodium falciparum acid cluster protein 33 homologue, putative 0.0046 0.0016 0.0133
Trypanosoma brucei trypanothione synthetase, putative 0.0069 0.0154 0.0317
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0647 0.3661 0.7513
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Brugia malayi Cathepsin L-like precursor 0.0076 0.0193 0.0561
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0126 0.0366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus GPI anchor transamidase 0.0063 0.0115 0.0333
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0027 0.0027
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0117 0.0447 0.0942
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0128 0.0512 0.1489
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0029 0.0158
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0128 0.0512 0.1486
Leishmania major otubain, putative,otubain cysteine peptidase, Clan CA, family C65, putative 0.0088 0.027 0.0522
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Giardia lamblia Cysteine protease 0.0049 0.0029 0.0611
Giardia lamblia Nuclear ATP/GTP-binding protein 0.0121 0.047 1
Plasmodium vivax GPI-anchor transamidase, putative 0.0063 0.0115 0.0728
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0847 0.4873 1
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0225 0.1097 0.6037
Loa Loa (eye worm) hypothetical protein 0.0116 0.0438 0.1274
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.005 0.0037 0.0106
Onchocerca volvulus 0.0053 0.0055 0.0161
Schistosoma mansoni survival motor neuron protein 0.0049 0.0032 0.0094
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.0442 0.2415 0.4956
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0029 0.0083
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.0442 0.2415 0.4956
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Toxoplasma gondii subtilisin SUB12 0.0053 0.0055 0.0138
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0418 0.2271 0.4661
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0102 0.035 0.1018
Plasmodium falciparum ubiquitin specific protease, putative 0.0045 0.0008 0.0063
Brugia malayi cathepsin L-like precursor 0.0159 0.0701 0.204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus cathepsin L cysteine proteinase 0.0235 0.1159 0.3366
Trypanosoma brucei inhibitor of cysteine peptidase 0.024 0.1193 0.2447
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0049 0.0029 0.0236
Brugia malayi Cathepsin L-like precursor 0.0235 0.1159 0.3373
Echinococcus granulosus ubiquitin specific peptidase c family 0.0135 0.0555 0.1611
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0413 0.2238 0.4594
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0066 0.0136 0.0372
Trypanosoma brucei antigen, putative 0.0284 0.1455 0.2987
Echinococcus multilocularis abhydrolase domain containing protein 3 0.0046 0.0016 0.0034
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0066 0.0136 0.0395
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0275 0.1405 0.2884
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Leishmania major cysteine peptidase A (CPA) 0.0235 0.1159 0.2353
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0409 0.2217 0.4549
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0225 0.1097 0.6037
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0063 0.0115 0.0235
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Entamoeba histolytica protein kinase, putative 0.0059 0.0093 0.0611
Plasmodium vivax hypothetical protein, conserved 0.0121 0.047 0.2983
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0615 0.3462 0.7104
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0084 0.0246 0.1353
Loa Loa (eye worm) calpain 5 0.0059 0.0093 0.0271
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0239 0.1182 0.2426
Echinococcus granulosus cytosolic carboxypeptidase 1 0.0121 0.047 0.1365
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0045 0.0008 0.0022
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0045 0.0008 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Giardia lamblia Cathepsin L precursor 0.0049 0.0029 0.0611
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0055 0.0161
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0269 0.1363 0.2798
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Trypanosoma cruzi cysteine proteinase, putative 0.0124 0.0487 0.0999
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0049 0.0029 0.0182
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0045 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0063 0.0115 0.0334
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0847 0.4873 1
Echinococcus multilocularis abhydrolase domain containing protein 0.0046 0.0016 0.0034
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0027 0.008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0082 0.0233 0.1284
Schistosoma mansoni cathepsin D (A01 family) 0.0312 0.1628 0.4727
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0284 0.1455 0.4227
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Trypanosoma brucei small myristoylated protein 1-1 0.0429 0.2337 0.4796
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0225 0.1097 0.3192
Giardia lamblia Cysteine protease 0.0049 0.0029 0.0611
Brugia malayi calpain D 0.0295 0.1525 0.4438
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0477 0.263 0.5397
Giardia lamblia Cathepsin L precursor 0.0049 0.0029 0.0611
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.064 0.3614 0.7417
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.008 0.022 0.121
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0029 0.0059
Entamoeba histolytica calpain large subunit domain III containing protein 0.0059 0.0093 0.0611
Trypanosoma cruzi hydrolase-like protein, putative 0.0046 0.0016 0.0033
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0049 0.0029 0.0083
Trypanosoma cruzi major cysteine proteinase, putative 0.0241 0.1198 0.2458
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0107 0.038 0.075
Brugia malayi CG8232-PA 0.0061 0.0105 0.0304
Trypanosoma brucei cysteine peptidase, putative 0.0584 0.3277 0.6725
Plasmodium vivax vivapain-2 0.0235 0.1159 0.7356
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0269 0.1363 0.2798
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Onchocerca volvulus 0.0089 0.0273 0.0793
Schistosoma mansoni calpain-7 (C02 family) 0.0361 0.1926 0.5595
Loa Loa (eye worm) hypothetical protein 0.0128 0.0512 0.1489
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0045 0.0008 0.0022
Schistosoma mansoni family S33 non-peptidase homologue (S33 family) 0.0046 0.0016 0.0047
Entamoeba histolytica cysteine proteinase 1, putative 0.0124 0.0487 0.3193
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Trypanosoma brucei kinesin, putative 0.0059 0.0093 0.0191
Plasmodium vivax unspecified product 0.0076 0.0193 0.1222
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.005 0.0037 0.024
Echinococcus multilocularis abhydrolase domain containing 3 0.0046 0.0016 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.0159 0.0701 0.4595
Plasmodium vivax unspecified product 0.0124 0.0487 0.309
Loa Loa (eye worm) hypothetical protein 0.0046 0.0016 0.0047
Schistosoma mansoni cathepsin C 0.0049 0.0029 0.0083
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0045 0.0008 0.0049
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Loa Loa (eye worm) cysteine protease 0.0235 0.1159 0.3373
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.1196 0.252
Trypanosoma cruzi cysteine peptidase, putative 0.0124 0.0487 0.0999
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0066 0.0136 0.0395
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Leishmania major small myristoylated protein-1 0.0429 0.2337 0.4779
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0275 0.1405 0.2884
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0016 0.0103
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0116 0.0437 0.2865
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0049 0.0029 0.0158
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.005 0.0037 0.0077
Plasmodium vivax unspecified product 0.0049 0.0029 0.0182
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0521 0.2892 0.6093
Mycobacterium tuberculosis Probable haloalkane dehalogenase 0.0046 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.005 0.004 0.0116
Brugia malayi Cathepsin L-like precursor 0.0235 0.1159 0.3373
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0049 0.0029 0.0182
Loa Loa (eye worm) zinc carboxypeptidase 0.0174 0.0787 0.229
Echinococcus granulosus cathepsin b 0.0112 0.0414 0.1203
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0117 0.0447 0.1298
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0027 0.0023
Trichomonas vaginalis hypothetical protein 0.0225 0.1097 0.6037
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0079 0.0216 0.1189
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0067 0.0142 0.0781
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0188 0.0385
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0027 0.6836
Trypanosoma cruzi unspecified product 0.0429 0.2337 0.4796
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0112 0.0414 0.228
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0029 0.0084
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0049 0.0029 0.0083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0679 0.3852 0.7897
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0029 0.0084
Schistosoma mansoni hypothetical protein 0.0091 0.0284 0.0824
Loa Loa (eye worm) hypothetical protein 0.0088 0.027 0.0785
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0235 0.1159 0.9525
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0049 0.0029 0.0182
Brugia malayi cathepsin L precursor 0.0049 0.0029 0.0084
Mycobacterium ulcerans hypothetical protein 0.0046 0.0016 0.0016
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0493 0.2726 0.5579
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0803 0.4604 0.9447
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0116 0.0438 0.1271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0201 0.0953 0.1956
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0029 0.0158
Giardia lamblia Encystation-specific protease 0.0049 0.0029 0.0611
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0082 0.0233 0.0654
Onchocerca volvulus 0.0121 0.047 0.1365
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi hypothetical protein, conserved 0.0275 0.1405 0.2884
Echinococcus multilocularis calpain 7 (C02 family) 0.0316 0.1653 0.3484
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0409 0.2217 0.4531
Mycobacterium ulcerans epoxide hydrolase EphF 0.0046 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0159 0.0701 0.204
Plasmodium falciparum cysteine proteinase falcipain 3 0.0235 0.1159 0.9525
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14, putative 0.0121 0.047 0.0964
Plasmodium falciparum GPI-anchor transamidase, putative 0.0063 0.0115 0.0943
Brugia malayi fibroinase precursor 0.0049 0.0029 0.0084
Schistosoma mansoni hypothetical protein 0.0045 0.0008 0.0022
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0552 0.3085 0.633
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0045 0.0008 0.0016
Trypanosoma cruzi small myristoylated protein 1-1 0.0429 0.2337 0.4796
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0029 0.0158
Brugia malayi Zinc carboxypeptidase family protein 0.0121 0.047 0.1368
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0188 0.0385
Brugia malayi Zinc carboxypeptidase family protein 0.0174 0.0787 0.229
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0027 0.0023
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0073 0.0176 0.0513
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0135 0.0555 0.1138
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Onchocerca volvulus 0.0235 0.1159 0.3366
Echinococcus granulosus geminin 0.0171 0.0772 0.2243
Entamoeba histolytica peptidase, C54 family 0.0201 0.0953 0.6252
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus multilocularis subfamily M14A unassigned peptidase 0.0611 0.3443 0.7256
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0102 0.035 0.0719
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0049 0.0029 0.0236
Echinococcus multilocularis calpain 0.0284 0.1455 0.3067
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.005 0.0037 0.0106
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0045 0.0008 0.0022
Giardia lamblia GPI-anchor transamidase, putative 0.0063 0.0115 0.2441
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Onchocerca volvulus 0.0235 0.1159 0.3366
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0046 0.0016 0.0089
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0045 0.0008 0.0022
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.0088 0.027 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0701 0.3857
Trypanosoma cruzi calpain cysteine peptidase, putative 0.05 0.2767 0.5679
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0045 0.0008 0.0016
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0584 0.3277 0.6714
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Toxoplasma gondii microneme protein, putative 0.0053 0.0055 0.0138
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.008 0.022 0.0638
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0053 0.0055 0.0138
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0679 0.3852 0.7897
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0185 0.0856 0.1729
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.008 0.022 0.064
Trypanosoma cruzi ubiquitin hydrolase, putative 0.016 0.0706 0.145
Mycobacterium ulcerans peroxidase BpoB 0.0046 0.0016 0.0016
Trypanosoma cruzi zinc carboxypeptidase, putative 0.0121 0.047 0.0964
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0128 0.0512 0.3248
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.0116 0.0437 0.359
Entamoeba histolytica cysteine proteinase, putative 0.0124 0.0487 0.3193
Trypanosoma cruzi hydrolase-like protein 0.0046 0.0016 0.0033
Entamoeba histolytica peptidase, C54 family 0.0047 0.0021 0.014
Toxoplasma gondii cathepsin CPC2 0.0049 0.0029 0.0061
Schistosoma mansoni family M14 non-peptidase homologue (M14 family) 0.0121 0.047 0.1365
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0269 0.1363 0.2798
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0647 0.3661 0.7505
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0077 0.0204 0.0594
Mycobacterium ulcerans haloalkane dehalogenase 0.0046 0.0016 0.0016
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0062 0.0113 0.0231
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0008 0.0163
Trichomonas vaginalis ubiquitin specific protease, putative 0.0045 0.0008 0.0042
Echinococcus granulosus abhydrolase domain containing protein 3 0.0046 0.0016 0.0047
Onchocerca volvulus 0.0053 0.0055 0.0161
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0128 0.0512 0.105
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0112 0.0414 0.1203
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0037 0.0106
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0066 0.0136 0.0279
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Schistosoma mansoni peptidase 0.0045 0.0008 0.0022
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0128 0.0512 0.1078
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.006 0.0096 0.0787
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0079 0.0216 0.1189
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0073 0.0176 0.0362
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0117 0.0447 0.246
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0102 0.035 0.102
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0055 0.0138
Loa Loa (eye worm) hypothetical protein 0.0059 0.0093 0.0271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma brucei metallo-peptidase, Clan MC, Family M14, putative 0.0121 0.047 0.0964
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Loa Loa (eye worm) hypothetical protein 0.0073 0.0176 0.0513
Brugia malayi cathepsin F-like cysteine proteinase 0.0049 0.0029 0.0084
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Onchocerca volvulus 0.0053 0.0055 0.0161
Mycobacterium ulcerans hypothetical protein 0.0046 0.0016 0.0016
Trypanosoma cruzi trypanothione synthetase 0.0069 0.0154 0.0317
Giardia lamblia Cathepsin B precursor 0.0049 0.0029 0.0611
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0045 0.0008 0.0063
Onchocerca volvulus 0.0045 0.0008 0.0022
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.016 0.0706 0.1421
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.05 0.2767 0.5679
Onchocerca volvulus Epoxide hydrolase 1 homolog 0.0046 0.0016 0.0047
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0135 0.0555 0.1138
Toxoplasma gondii alpha/beta hydrolase, putative 0.0046 0.0016 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0049 0.0029 0.0236
Plasmodium falciparum plasmepsin I 0.0117 0.0447 0.3673
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Giardia lamblia Cathepsin B precursor 0.0049 0.0029 0.0611
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0063 0.0115 0.0631
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0029 0.0158
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0016 0.0033
Leishmania major calpain family cysteine protease-like protein 0.0571 0.3196 0.6547
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.008 0.022 0.0451
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.1998 0.4101
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0413 0.2238 0.4594
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0188 0.1033
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0079 0.0216 0.0628
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0418 0.2271 0.4661
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0428 0.2328 0.4777
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Schistosoma mansoni calpain-2 (C02 family) 0.0225 0.1097 0.3185
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0126 0.0365
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Mycobacterium leprae Probable exported protease 0.0046 0.0016 0.4043
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Schistosoma mansoni cathepsin D (A01 family) 0.0312 0.1628 0.4727
Plasmodium falciparum cysteine protease ATG4, putative 0.0047 0.0021 0.0175
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0063 0.0115 0.0631
Plasmodium falciparum serine repeat antigen 2 0.0049 0.0029 0.0236
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0032 0.0094
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0049 0.0029 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0084 0.0246 0.0504
Entamoeba histolytica hypothetical protein 0.0046 0.0016 0.0106
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0629 0.355 0.7277
Onchocerca volvulus Cathepsin L homolog 0.0235 0.1159 0.3366
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.005 0.0037 0.0232
Echinococcus multilocularis lysosomal acid lipase:cholesteryl ester 0.0046 0.0016 0.0034
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.345
Toxoplasma gondii PAN/Apple domain-containing protein 0.0053 0.0055 0.0138
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0275 0.1405 0.2884
Leishmania major receptor-type adenylate cyclase a-like protein 0.0275 0.1405 0.286
Schistosoma mansoni calpain (C02 family) 0.0284 0.1455 0.4227
Echinococcus multilocularis calpain 5 0.0284 0.1455 0.3067
Giardia lamblia Hypothetical protein 0.0049 0.0029 0.0611
Schistosoma mansoni hypothetical protein 0.0049 0.0032 0.0094
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0075 0.0188 0.0546
Mycobacterium ulcerans hypothetical protein 0.0046 0.0016 0.0016
Trypanosoma brucei glutathionylspermidine synthetase, putative 0.0069 0.0154 0.0317
Brugia malayi UPF0017 protein CG3488 0.0046 0.0016 0.0047
Echinococcus granulosus subfamily M14A unassigned peptidase 0.0611 0.3443 1
Loa Loa (eye worm) calpain family protein 1 0.0225 0.1097 0.3192
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.0442 0.2415 0.4939
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0201 0.0953 0.1956
Plasmodium falciparum epoxide hydrolase 1 0.0046 0.0016 0.0133
Echinococcus multilocularis cathepsin L cysteine protease 0.0235 0.1159 0.2442
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0373 0.1998 0.4101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0049 0.0029 0.0611
Brugia malayi Cathepsin L-like precursor 0.0235 0.1159 0.3373
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0062 0.0113 0.0199
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Mycobacterium ulcerans homoserine O-acetyltransferase 0.0046 0.0016 0.0016
Echinococcus granulosus lysosomal acid lipase:cholesteryl ester 0.0046 0.0016 0.0047
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0124 0.0487 0.0999
Echinococcus granulosus calpain A 0.0284 0.1455 0.4227
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0045 0.0008 0.0022
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0116 0.0437 0.0866
Loa Loa (eye worm) zinc carboxypeptidase 0.0121 0.047 0.1368
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0079 0.0216 0.1189
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0066 0.0136 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0029 0.0158
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0045 0.0008 0.0016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0029 0.0084
Onchocerca volvulus 0.0049 0.0029 0.0083
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0275 0.1405 0.2884
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0126 0.0365
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0045 0.0008 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0418 0.2271 0.4661
Trypanosoma cruzi metallo-peptidase, Clan MC, Family M14, putative 0.0121 0.047 0.0964
Trypanosoma cruzi hypothetical protein, conserved 0.0343 0.1817 0.3728
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0045 0.0008 0.0049
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0161
Trichomonas vaginalis ubiquitin specific protease, putative 0.0065 0.0128 0.0705
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0112 0.0414 0.1203
Brugia malayi Cathepsin L-like precursor 0.0235 0.1159 0.3373
Brugia malayi Cathepsin L-like precursor 0.0159 0.0701 0.204
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0029 0.0158
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0076 0.0193 0.0561
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0084 0.0246 0.0714
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0027 0.008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0116 0.0438 0.1271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Toxoplasma gondii zinc carboxypeptidase, putative 0.0121 0.047 0.1341
Echinococcus multilocularis cathepsin L 0.0124 0.0487 0.1026
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0016 0.0103
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0124 0.0487 0.0999
Leishmania major hypothetical protein, conserved 0.0091 0.0284 0.0551
Leishmania major hypothetical protein, conserved 0.0275 0.1405 0.286
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0037 0.0201
Trypanosoma cruzi glutathionylspermidine synthase, putative 0.0069 0.0154 0.0317
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0266 0.1348 0.2766
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma brucei hydrolase, alpha/beta fold family, putative 0.0046 0.0016 0.0033
Plasmodium falciparum serine repeat antigen 7 0.0049 0.0029 0.0236
Echinococcus granulosus cathepsin l1 0.0159 0.0701 0.2035
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0239 0.1182 0.2426
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0284 0.1455 0.3067
Loa Loa (eye worm) TK/ROR protein kinase 0.0091 0.0284 0.0826
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0066 0.0136 0.0749
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0027 0.0027
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0029 0.0083
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0049 0.0029 0.0084
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0128 0.0512 0.4205
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.0116 0.0437 0.1271
Mycobacterium ulcerans hydrolase 0.0046 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Trypanosoma brucei calpain-like protein, putative 0.0552 0.3085 0.633
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0112 0.0414 0.1203
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.005 0.0037 0.0106
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0029 0.0611
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0049 0.0029 0.0083
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0073 0.0176 0.1449
Giardia lamblia DUB-1 0.0045 0.0008 0.0163
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0128 0.0512 0.1486
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Onchocerca volvulus 0.005 0.004 0.0116
Schistosoma mansoni calpain C (C02 family) 0.0284 0.1455 0.4227
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0117 0.0447 0.1274
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Entamoeba histolytica cysteine protease, putative 0.0049 0.0029 0.0188
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0027 0.0027
Mycobacterium ulcerans hypothetical protein 0.0102 0.0352 0.0352
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0201 0.0953 0.1956
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0066 0.0136 0.0247
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0584 0.3277 0.6725
Giardia lamblia Cathepsin L-like protease 0.0049 0.0029 0.0611
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0079 0.0216 0.0628
Loa Loa (eye worm) hypothetical protein 0.0048 0.0027 0.008
Toxoplasma gondii aspartyl protease ASP1 0.0117 0.0447 0.1274
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Mycobacterium ulcerans short chain dehydrogenase 0.005 0.004 0.004
Plasmodium falciparum ubiquitin specific protease, putative 0.0045 0.0008 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0027 0.008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Plasmodium falciparum serine repeat antigen 8 0.0049 0.0029 0.0236
Wolbachia endosymbiont of Brugia malayi phosphatase 0.0044 0 0.5
Brugia malayi ubiquitin specific protease 14 0.0073 0.0176 0.0513
Loa Loa (eye worm) hypothetical protein 0.0046 0.0016 0.0047
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0847 0.4873 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0701 0.3857
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0117 0.0447 0.1301
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.345
Leishmania major cathepsin L-like protease 0.0235 0.1159 0.2353
Onchocerca volvulus Subfamily M14A unassigned peptidase homolog 0.0611 0.3443 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0049 0.0029 0.0182
Plasmodium vivax vivapain-3 0.0124 0.0487 0.309
Mycobacterium ulcerans non-heme haloperoxidase Hpx 0.0046 0.0016 0.0016
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0079 0.0216 0.1775
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Echinococcus multilocularis abhydrolase domain containing protein 16A 0.0046 0.0016 0.0034
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0055 0.0161
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Loa Loa (eye worm) calpain family protein 1 0.0284 0.1455 0.4236
Brugia malayi calpain 7 0.0316 0.1653 0.4812
Loa Loa (eye worm) hypothetical protein 0.0121 0.047 0.1368
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.008 0.022 0.0463
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0135 0.0555 0.1109
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0079 0.0216 0.0628
Leishmania major zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 0.0121 0.047 0.0934
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0217 0.1049 0.2152
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0027 0.0027
Toxoplasma gondii hypothetical protein 0.0053 0.0055 0.0138
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0063 0.0115 0.0631
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Loa Loa (eye worm) hypothetical protein 0.0052 0.0051 0.0149
Entamoeba histolytica cysteine protease, putative 0.0124 0.0487 0.3193
Leishmania major small myristoylated protein 4, putative 0.064 0.3614 0.7409
Trypanosoma cruzi hypothetical protein, conserved 0.0275 0.1405 0.2884
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0116 0.0437 0.092
Brugia malayi Zinc carboxypeptidase family protein 0.0174 0.0787 0.229
Trypanosoma brucei calpain-like protein, putative 0.0304 0.1575 0.3233
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.008 0.022 0.0451
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0193 0.0395
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Plasmodium falciparum calpain 0.0244 0.1217 1
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.0116 0.0437 0.2772
Plasmodium falciparum serine repeat antigen 9 0.0049 0.0029 0.0236
Loa Loa (eye worm) cathepsin B 0.0112 0.0414 0.1206
Schistosoma mansoni cathepsin s 0.0076 0.0193 0.0559
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0116 0.0437 0.1244
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0235 0.1159 0.6379
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0027 0.0027
Onchocerca volvulus 0.0091 0.0284 0.0824
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Schistosoma mansoni hypothetical protein 0.0171 0.0772 0.2243
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0552 0.3085 0.6318
Mycobacterium ulcerans lignin peroxidase LipJ 0.0046 0.0016 0.0016
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0082 0.0233 0.0678
Brugia malayi Peptidase family C54 containing protein 0.0084 0.0246 0.0715
Onchocerca volvulus 0.0611 0.3443 1
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0847 0.4873 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0112 0.0414 0.082
Mycobacterium tuberculosis Probable oxidoreductase 0.0046 0.0016 0.0016
Echinococcus multilocularis cysteine protease 0.0235 0.1159 0.2442
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0244 0.1217 0.3506
Onchocerca volvulus 0.0053 0.0055 0.0161
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0135 0.0555 0.1611
Echinococcus granulosus cathepsin l cysteine peptidase 0.0235 0.1159 0.3366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0073 0.0176 0.0512
Onchocerca volvulus 0.0045 0.0008 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0102 0.035 0.1018
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.006 0.0096 0.0527
Echinococcus granulosus abhydrolase domain containing protein 11 0.0046 0.0016 0.0047
Entamoeba histolytica GPI-anchor transamidase, putative 0.0063 0.0115 0.0752
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0107 0.038 0.1105
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0161
Entamoeba histolytica alpha/beta hydrolase fold protein, putative 0.0046 0.0016 0.0106
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0029 0.0158
Trypanosoma cruzi hypothetical protein, conserved 0.0343 0.1817 0.3728
Entamoeba histolytica cysteine proteinase, putative 0.0124 0.0487 0.3193
Mycobacterium ulcerans hypothetical protein 0.0046 0.0016 0.0016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0027 0.0027
Onchocerca volvulus Cathepsin L homolog 0.0049 0.0029 0.0083
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0049 0.0029 0.0182
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Brugia malayi LD47325p 0.0052 0.0051 0.0149
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0239 0.1182 0.2401
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0233 0.0479
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Mycobacterium leprae Possible short-chain dehydrogenase EphD 0.005 0.004 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0239 0.1182 0.2426
Echinococcus granulosus tissue type plasminogen activator 0.0091 0.0284 0.0824
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0045 0.0008 0.0022
Brugia malayi Papain family cysteine protease containing protein 0.0124 0.0487 0.1417
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0239 0.1182 0.2426
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0063 0.0118 0.0243
Brugia malayi GPI-anchor transamidase 0.0063 0.0115 0.0334
Entamoeba histolytica peptidase, C54 family 0.0047 0.0021 0.014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Trypanosoma brucei trypanothione synthetase 0.0069 0.0154 0.0317
Trichomonas vaginalis ubiquitin specific protease, putative 0.0045 0.0008 0.0042
Entamoeba histolytica cysteine proteinase, putative 0.0235 0.1159 0.76
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Plasmodium falciparum cysteine proteinase falcipain 1 0.0124 0.0487 0.4002
Echinococcus granulosus cathepsin L 0.0049 0.0029 0.0083
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0271 0.1377 0.2826
Trichomonas vaginalis Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase 0.0121 0.047 0.2587
Leishmania major hypothetical protein, conserved 0.0275 0.1405 0.286
Toxoplasma gondii microneme protein MIC17B 0.0053 0.0055 0.0138
Giardia lamblia ENC6 protein 0.0046 0.0016 0.0345
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0029 0.0158
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0049 0.0029 0.0188
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0239 0.1182 0.2426
Brugia malayi RNA binding protein 0.0065 0.0126 0.0366
Onchocerca volvulus 0.0053 0.0055 0.0161
Echinococcus multilocularis cysteine protease 0.0235 0.1159 0.2442
Brugia malayi Carboxypeptidase A2 precursor 0.0121 0.047 0.1368
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.016 0.0706 0.4633
Entamoeba histolytica hypothetical protein 0.0049 0.0029 0.0188
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0046 0.0016 0.0089
Loa Loa (eye worm) hypothetical protein 0.0241 0.1196 0.348
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0552 0.3085 0.633
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0008 0.005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0161
Plasmodium falciparum serine repeat antigen 6 0.0049 0.0029 0.0236
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0107 0.038 0.0781
Echinococcus multilocularis tissue type plasminogen activator 0.0091 0.0284 0.0598
Giardia lamblia Cathepsin B precursor 0.0112 0.0414 0.8814
Schistosoma mansoni hypothetical protein 0.0121 0.047 0.1365
Brugia malayi Alpha/beta hydrolase 0.0046 0.0016 0.0047
Trypanosoma cruzi cysteine peptidase, putative 0.0428 0.2328 0.4777
Loa Loa (eye worm) hypothetical protein 0.0045 0.0008 0.0022
Entamoeba histolytica peptidase, C54 family 0.0047 0.0021 0.014
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.3428
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0124 0.0487 0.1414
Loa Loa (eye worm) hypothetical protein 0.0049 0.0029 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0029 0.0158
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0193 0.0395
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0043
Brugia malayi Zinc carboxypeptidase family protein 0.0121 0.047 0.1368
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Loa Loa (eye worm) ctsf protein 0.0235 0.1159 0.3373
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0066 0.0136 0.0749
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0102 0.035 0.102
Trypanosoma brucei conserved protein 0.0221 0.1075 0.2205
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0239 0.1182 0.2401
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0225 0.1097 0.6037
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0045 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0061 0.0105 0.0304
Onchocerca volvulus 0.0053 0.0055 0.0161
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0847 0.4873 1
Brugia malayi Trypsin family protein 0.0116 0.0438 0.1274
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.008 0.022 0.0419
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0045 0.0008 0.0042
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0045 0.0008 0.0022
Trypanosoma brucei calpain-like protein, putative 0.0304 0.1575 0.3233
Echinococcus multilocularis expressed protein 0.0045 0.0008 0.0016
Toxoplasma gondii zinc carboxypeptidase superfamily protein 0.0121 0.047 0.1341
Onchocerca volvulus 0.0235 0.1159 0.3366
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0124 0.0487 0.1414
Onchocerca volvulus 0.0235 0.1159 0.3366
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0275 0.1405 0.2884
Mycobacterium leprae POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) 0.0046 0.0016 0.4043
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Giardia lamblia Hypothetical protein 0.0049 0.0029 0.0611
Leishmania major PFPI/DJ-1-like protein, putative 0.0464 0.2548 0.5213
Trypanosoma cruzi cysteine peptidase inhibitor 0.024 0.1193 0.2447
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.061 0.3436 1
Brugia malayi PAN domain containing protein 0.0053 0.0055 0.0161
Plasmodium falciparum serine repeat antigen 1 0.0049 0.0029 0.0236
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0045 0.0008 0.0022
Giardia lamblia Hypothetical protein 0.005 0.0037 0.0777
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0008 0.0042
Loa Loa (eye worm) hypothetical protein 0.0049 0.0029 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0235 0.1159 0.6379
Onchocerca volvulus 0.0053 0.0055 0.0161
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0584 0.3277 0.6725
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0045 0.0008 0.0022
Loa Loa (eye worm) hypothetical protein 0.0053 0.0055 0.0161
Loa Loa (eye worm) hypothetical protein 0.0049 0.0029 0.0084
Loa Loa (eye worm) hypothetical protein 0.0049 0.0029 0.0084
Loa Loa (eye worm) hypothetical protein 0.0048 0.0027 0.008
Echinococcus multilocularis Zinc carboxypeptidase family protein 0.0121 0.047 0.099
Mycobacterium leprae POSSIBLE SECRETED PROTEASE 0.0046 0.0016 0.4043
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0049 0.0029 0.0182
Giardia lamblia Cathepsin L precursor 0.0049 0.0029 0.0611
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0029 0.0083
Treponema pallidum phosphoglycolate phosphatase 0.0044 0 0.5
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0321 0.1681 0.345
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0016 0.0033
Leishmania major cathepsin L-like protease 0.0428 0.2328 0.476
Entamoeba histolytica cysteine protease, putative 0.0049 0.0029 0.0188
Entamoeba histolytica cysteine proteinase 2 0.0124 0.0487 0.3193
Onchocerca volvulus 0.0049 0.0032 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0008 0.0042
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.005 0.0037 0.0201
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0028 0.0028
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.005 0.0037 0.0106

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 1.9 uM In vitro inhibition of histamine release from human basophils ChEMBL. 8410986
IC50 (functional) = 1.9 uM In vitro inhibition of histamine release from human basophils ChEMBL. 8410986

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 8410986

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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