Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | heat shock protein, putative | 0.0032 | 0.0702 | 0.2158 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0201 | 0.0201 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0041 | 0.1002 | 0.1836 |
Echinococcus granulosus | heat shock protein | 0.0048 | 0.1229 | 0.2251 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0827 | 0.0827 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0321 | 0.0281 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0523 | 0.1517 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.1279 | 0.4221 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0017 | 0.0222 | 0.0395 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0017 | 0.0222 | 0.5 |
Brugia malayi | Endoplasmin precursor | 0.0048 | 0.1229 | 0.1229 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0022 | 0.0383 | 0.0683 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.1279 | 0.4221 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0025 | 0.0482 | 0.0482 |
Plasmodium vivax | heat shock protein 86, putative | 0.0048 | 0.1229 | 0.188 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0113 | 0.3351 | 0.8435 |
Trypanosoma brucei | polo-like protein kinase | 0.0099 | 0.2893 | 1 |
Brugia malayi | Hsp90 protein | 0.0032 | 0.0702 | 0.0702 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0201 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0523 | 0.0523 |
Trichomonas vaginalis | heat shock protein, putative | 0.0045 | 0.1132 | 0.3697 |
Plasmodium falciparum | heat shock protein 90 | 0.0048 | 0.1229 | 0.2193 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0321 | 0.0321 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0201 | 0.0201 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0827 | 0.0827 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.1279 | 0.2282 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2893 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0035 | 0.0799 | 0.2503 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0201 | 0.0368 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0032 | 0.0702 | 0.2158 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.1279 | 0.1279 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0218 | 0.0218 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0099 | 0.2893 | 0.2356 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0116 | 0.0059 |
Leishmania major | trypanothione reductase | 0.005 | 0.1279 | 0.4221 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0017 | 0.0222 | 0.001 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0321 | 0.0589 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0321 | 0.0793 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0523 | 0.0523 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0321 | 0.0281 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0321 | 0.111 |
Trichomonas vaginalis | endoplasmin, putative | 0.0035 | 0.0799 | 0.2503 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0201 | 0.0368 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0892 | 0.2836 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.1279 | 0.1279 |
Plasmodium falciparum | thioredoxin reductase | 0.0017 | 0.0222 | 0.0395 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0113 | 0.3351 | 0.8837 |
Echinococcus granulosus | endoplasmin | 0.0045 | 0.1132 | 0.2074 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0201 | 0.0368 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0045 | 0.1132 | 0.3697 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0222 | 0.0436 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0025 | 0.0482 | 0.137 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0032 | 0.0702 | 0.2158 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0321 | 0.0589 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.0222 | 0.0436 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.1279 | 0.2343 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Echinococcus granulosus | heat shock protein 90 | 0.0048 | 0.1229 | 0.2251 |
Plasmodium falciparum | glutathione reductase | 0.0017 | 0.0222 | 0.0395 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Treponema pallidum | heat shock protein 90 | 0.0045 | 0.1132 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0201 | 0.0368 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0048 | 0.1229 | 0.4042 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0201 | 0.0368 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0321 | 0.0589 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.5458 | 1 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0182 | 0.5602 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0201 | 0.0368 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0892 | 0.2836 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0099 | 0.2893 | 0.53 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0523 | 0.057 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Brugia malayi | glutathione reductase | 0.005 | 0.1279 | 0.1279 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0892 | 0.1634 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0113 | 0.3351 | 0.8837 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0321 | 0.0589 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.0222 | 0.0436 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Giardia lamblia | Kinase, PLK | 0.0099 | 0.2893 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.1279 | 0.1973 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.1279 | 0.2343 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Echinococcus multilocularis | heat shock protein 90 | 0.0041 | 0.1002 | 0.1836 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0048 | 0.1229 | 0.4042 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0041 | 0.1002 | 0.3464 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.1279 | 0.1279 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0125 | 0.3745 | 0.3745 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0012 | 0.0048 | 0.0087 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0201 | 0.0201 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0048 | 0.0087 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0041 | 0.1002 | 0.3231 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2893 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0321 | 0.0589 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.1366 | 0.1366 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0201 | 0.0368 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0321 | 0.0793 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Schistosoma mansoni | kinase | 0.005 | 0.1303 | 0.2388 |
Echinococcus granulosus | bloom syndrome protein | 0.0025 | 0.0482 | 0.0884 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0222 | 0.0406 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0321 | 0.0589 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0892 | 0.0892 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0222 | 0.0222 |
Echinococcus multilocularis | heat shock protein | 0.0048 | 0.1229 | 0.2251 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0321 | 0.1094 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0025 | 0.0482 | 0.137 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0048 | 0.1229 | 0.4042 |
Loa Loa (eye worm) | RecQ helicase | 0.0025 | 0.0482 | 0.0482 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.1261 | 0.4157 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.1366 | 0.1366 |
Trichomonas vaginalis | heat shock protein, putative | 0.0041 | 0.1002 | 0.3231 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0827 | 0.1515 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0099 | 0.2893 | 0.2893 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0045 | 0.1132 | 1 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0321 | 0.0793 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0048 | 0.1229 | 0.4247 |
Loa Loa (eye worm) | hypothetical protein | 0.0317 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0321 | 0.0321 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0048 | 0.1229 | 0.4042 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0099 | 0.2893 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.1279 | 0.2985 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0321 | 0.0793 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0321 | 0.0321 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0523 | 0.0934 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0048 | 0.1229 | 0.4042 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0523 | 0.0934 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0321 | 0.0589 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.002 | 0.0309 | 0.0567 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0126 | 0.3763 | 1 |
Schistosoma mansoni | heat shock protein | 0.0048 | 0.1229 | 0.2251 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0028 | 0.0572 | 0.1021 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0032 | 0.0702 | 0.1254 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2893 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.1279 | 0.1973 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0017 | 0.0222 | 0.0436 |
Brugia malayi | heat shock protein 90 | 0.0048 | 0.1229 | 0.1229 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0048 | 0.1229 | 0.4042 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0099 | 0.2893 | 0.2893 |
Trichomonas vaginalis | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0017 | 0.0222 | 0.0395 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2893 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0049 | 0.1261 | 0.4157 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0012 | 0.0048 | 0.0087 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0126 | 0.3763 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0013 | 0.0073 | 0.0073 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0126 | 0.3763 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0048 | 0.1229 | 0.1229 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0045 | 0.1132 | 0.2572 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0125 | 0.3745 | 0.3745 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0048 | 0.1229 | 0.2193 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.3795 | 0.3795 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0099 | 0.2893 | 0.53 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0182 | 0.5602 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.1279 | 0.2282 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0048 | 0.1229 | 0.4042 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2893 | 1 |
Plasmodium vivax | heat shock protein, putative | 0.0182 | 0.5602 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0321 | 0.0589 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2893 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0041 | 0.1002 | 0.3231 |
Leishmania major | heat shock protein, putative | 0.0032 | 0.0702 | 0.2158 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0113 | 0.3351 | 0.8837 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0321 | 0.0321 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0032 | 0.0702 | 0.1287 |
Schistosoma mansoni | endoplasmin | 0.0048 | 0.1229 | 0.2251 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0201 | 0.0368 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0099 | 0.2893 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0113 | 0.3351 | 0.8837 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0017 | 0.0222 | 0.0436 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Schistosoma mansoni | heat shock protein | 0.0048 | 0.1229 | 0.2251 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0222 | 0.0436 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0126 | 0.3763 | 1 |
Plasmodium falciparum | endoplasmin, putative | 0.0035 | 0.0799 | 0.1426 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0017 | 0.0222 | 0.001 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0321 | 0.0793 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0017 | 0.0222 | 0.0436 |
Loa Loa (eye worm) | endoplasmin | 0.0048 | 0.1229 | 0.1229 |
Mycobacterium tuberculosis | Probable reductase | 0.0113 | 0.3351 | 0.8837 |
Echinococcus multilocularis | bloom syndrome protein | 0.0025 | 0.0482 | 0.0884 |
Echinococcus granulosus | heat shock protein 90 | 0.0041 | 0.1002 | 0.1836 |
Echinococcus multilocularis | heat shock protein 90 | 0.0048 | 0.1229 | 0.2251 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0201 | 0.0201 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.002 | 0.0317 | 0.0779 |
Echinococcus granulosus | geminin | 0.0178 | 0.5458 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0222 | 0.0436 |
Echinococcus multilocularis | geminin | 0.0178 | 0.5458 | 1 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0099 | 0.2893 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0892 | 0.2836 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0321 | 0.0793 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0045 | 0.1132 | 1 |
Plasmodium vivax | heat shock protein 90, putative | 0.0032 | 0.0702 | 0.0903 |
Giardia lamblia | Grp94/Hsp90 | 0.0045 | 0.1132 | 0.3914 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0099 | 0.2893 | 1 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0032 | 0.0702 | 0.0702 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0892 | 0.1634 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0017 | 0.0222 | 0.0436 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0523 | 0.0934 |
Plasmodium vivax | endoplasmin, putative | 0.0048 | 0.1229 | 0.188 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0017 | 0.0222 | 0.0436 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0099 | 0.2893 | 0.53 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Schistosoma mansoni | endoplasmin | 0.0048 | 0.1229 | 0.2251 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0013 | 0.0073 | 0.0073 |
Onchocerca volvulus | 0.0317 | 1 | 1 | |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0321 | 0.0793 |
Echinococcus multilocularis | endoplasmin | 0.0045 | 0.1132 | 0.2074 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1366 | 0.1366 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0321 | 0.0589 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0523 | 0.1517 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0321 | 0.0793 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.0702 | 0.1287 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Trypanosoma brucei | heat shock protein, putative | 0.0048 | 0.1229 | 0.4042 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0201 | 0.0368 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0017 | 0.0222 | 0.0766 |
Trichomonas vaginalis | heat shock protein, putative | 0.0028 | 0.0572 | 0.1692 |
Brugia malayi | MH2 domain containing protein | 0.0125 | 0.3745 | 0.3745 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0017 | 0.0222 | 0.0395 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0222 | 0.0406 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0113 | 0.3351 | 0.8837 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0222 | 0.0406 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0048 | 0.1229 | 0.2193 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0017 | 0.0222 | 0.0395 |
Leishmania major | heat shock protein 83-1 | 0.0048 | 0.1229 | 0.4042 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0523 | 0.1517 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0892 | 0.1634 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0116 | 0.0059 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0892 | 0.1634 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0321 | 0.1094 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.1366 | 0.1366 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0116 | 0.0059 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0892 | 0.2836 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0017 | 0.021 | 0.0374 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0048 | 0.1229 | 0.4042 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0099 | 0.2893 | 1 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0032 | 0.0702 | 0.1287 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0321 | 0.0793 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.00000000015439 | 0.0000000002756 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0321 | 0.0793 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0014 | 0.0116 | 0.0059 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0523 | 0.1517 |
Trypanosoma brucei | unspecified product | 0.0014 | 0.0116 | 0.0059 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.1279 | 0.2282 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.5458 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0045 | 0.1132 | 0.3697 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Change (functional) | = -12 % | Percent change in plasma total cholesterol in cholesterol-fed rats at 200 mg/kg dose given in a period of 3 days | ChEMBL. | 2909740 |
Change (functional) | = -10 % | Change in plasma total cholesterol in normocholesterolemic rats at 0.2 % composition of dose with diet given in a period of 3 days. | ChEMBL. | 2909740 |
Change (functional) | = 16 % | The compound was tested for % change in plasma triglycerides in normocholesterolemic rats at 0.2 % composition of dose with diet given in a period of 3 days | ChEMBL. | 2909740 |
Change (functional) | = 23 % | Percent change in plasma triglycerides in cholesterol-fed rats at 200 mg/kg dose given in a period of 3 days | ChEMBL. | 2909740 |
Change (functional) | = 28 % | Percent change in plasma HDL cholesterol in cholesterol-fed rats at 200 mg/kg dose given in a period of 3 days | ChEMBL. | 2909740 |
Ratio (functional) | = 50 | Ratio of plasma HDL cholesterol/total cholesterol at 25 mg/kg for 3 days | ChEMBL. | 2909740 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.