Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0049 | 0.0014 | 0.0009 |
Schistosoma mansoni | smad1 5 8 and | 0.02 | 0.0536 | 0.1839 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0093 | 0.0166 | 0.0556 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.1985 |
Brugia malayi | steroid hormone receptor | 0.0093 | 0.0166 | 0.0161 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 0.5253 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0093 | 0.0166 | 0.0556 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0148 | 0.0355 | 0.0494 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0486 | 0.1523 | 0.5255 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0091 | 0.0159 | 0.441 |
Schistosoma mansoni | hypothetical protein | 0.0213 | 0.0581 | 0.1994 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0486 | 0.1523 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0674 | 0.2172 | 0.2168 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0049 | 0.0014 | 0.0034 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.009 | 0.0153 | 0.0148 |
Loa Loa (eye worm) | TAR-binding protein | 0.0884 | 0.2894 | 0.2891 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0049 | 0.0014 | 0.0009 |
Brugia malayi | MH1 domain containing protein | 0.0111 | 0.0226 | 0.0221 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0093 | 0.0166 | 0.0559 |
Loa Loa (eye worm) | Smad1 | 0.02 | 0.0536 | 0.0531 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.1985 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0049 | 0.0014 | 0.0009 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0213 | 0.0579 | 1 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0014 | 0.0009 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0213 | 0.0579 | 0.3779 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0093 | 0.0166 | 0.0161 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus multilocularis | tar DNA binding protein | 0.0884 | 0.2894 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0014 | 0.0009 |
Loa Loa (eye worm) | RNA binding protein | 0.0884 | 0.2894 | 0.2891 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0674 | 0.2172 | 0.2168 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0148 | 0.0355 | 0.1213 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0093 | 0.0166 | 0.0559 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.1985 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.009 | 0.0153 | 0.0148 |
Brugia malayi | MH2 domain containing protein | 0.02 | 0.0536 | 0.0531 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0093 | 0.0166 | 0.0227 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0093 | 0.0166 | 0.0227 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0057 | 0.0039 | 0.0118 |
Schistosoma mansoni | tar DNA-binding protein | 0.0884 | 0.2894 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0213 | 0.0581 | 0.0812 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0093 | 0.0166 | 0.0556 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0093 | 0.0166 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0461 | 0.1436 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0153 | 0.0148 |
Schistosoma mansoni | hypothetical protein | 0.0461 | 0.1436 | 0.4953 |
Brugia malayi | nuclear hormone receptor | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | GPCR family 2 | 0.0213 | 0.0581 | 0.0812 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0421 | 0.1298 | 0.4476 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.009 | 0.0153 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0213 | 0.0581 | 0.0576 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0213 | 0.0579 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 0.2143 |
Schistosoma mansoni | smad1 5 8 and | 0.02 | 0.0536 | 0.1839 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.009 | 0.0153 | 0.0512 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0213 | 0.0579 | 0.1985 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0884 | 0.2894 | 0.2891 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0213 | 0.0579 | 1 |
Brugia malayi | Probable ClpP-like protease | 0.0486 | 0.1523 | 0.1519 |
Echinococcus granulosus | FTZ F1 alpha | 0.2098 | 0.7087 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0884 | 0.2894 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0884 | 0.2894 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0213 | 0.0581 | 0.1994 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0163 | 0.0408 | 0.1396 |
Brugia malayi | TAR-binding protein | 0.0884 | 0.2894 | 0.2891 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0159 | 0.1942 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0319 | 0.0944 | 0.4744 |
Toxoplasma gondii | hypothetical protein | 0.0168 | 0.0422 | 0.2748 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0461 | 0.1436 | 0.1431 |
Onchocerca volvulus | 0.1265 | 0.4209 | 1 | |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.3779 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.1985 |
Schistosoma mansoni | Smad4 | 0.02 | 0.0536 | 0.1839 |
Echinococcus multilocularis | smad | 0.02 | 0.0536 | 0.1836 |
Echinococcus granulosus | smad | 0.02 | 0.0536 | 0.0749 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0166 | 0.0161 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0047 | 0.0005 | 0.0003 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0213 | 0.0581 | 0.0576 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | tar DNA binding protein | 0.0884 | 0.2894 | 0.408 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0014 | 0.0009 |
Schistosoma mansoni | tar DNA-binding protein | 0.0884 | 0.2894 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0159 | 0.1942 |
Loa Loa (eye worm) | hypothetical protein | 0.0421 | 0.1298 | 0.1293 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0126 | 0.028 | 0.2867 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0057 | 0.0039 | 0.0048 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0213 | 0.0579 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0039 | 0.0121 |
Schistosoma mansoni | smad1 5 8 and | 0.02 | 0.0536 | 0.1839 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0093 | 0.0166 | 0.0556 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.0355 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0126 | 0.028 | 0.2867 |
Onchocerca volvulus | 0.0093 | 0.0166 | 0.0031 | |
Schistosoma mansoni | glutaminase | 0.0283 | 0.0821 | 0.2825 |
Brugia malayi | RNA binding protein | 0.0884 | 0.2894 | 0.2891 |
Echinococcus multilocularis | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0163 | 0.0408 | 0.1393 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.0226 | 0.0221 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0093 | 0.0166 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0408 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0166 | 0.0161 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0486 | 0.1523 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0126 | 0.028 | 0.2867 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0093 | 0.0166 | 0.0556 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0148 | 0.0355 | 0.121 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0049 | 0.0014 | 0.0034 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0168 | 0.0422 | 0.2748 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0486 | 0.1523 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0421 | 0.1298 | 0.4474 |
Brugia malayi | MH1 domain containing protein | 0.02 | 0.0536 | 0.0531 |
Schistosoma mansoni | hypothetical protein | 0.0213 | 0.0581 | 0.1994 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0093 | 0.0166 | 0.0161 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0213 | 0.0579 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.2942 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0093 | 0.0166 | 0.0559 |
Loa Loa (eye worm) | pip kinase 2 | 0.0163 | 0.0408 | 0.0403 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0166 | 0.0161 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0421 | 0.1298 | 0.1293 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0166 | 0.0161 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0093 | 0.0166 | 0.0559 |
Echinococcus multilocularis | Smad4 | 0.02 | 0.0536 | 0.1836 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0213 | 0.0581 | 0.0576 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0213 | 0.0581 | 0.0576 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0093 | 0.0166 | 0.0227 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0093 | 0.0166 | 0.0559 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0091 | 0.0159 | 0.0154 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0093 | 0.0166 | 0.0161 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0166 | 0.0161 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0093 | 0.0166 | 0.0161 |
Onchocerca volvulus | 0.0163 | 0.0408 | 0.0628 | |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0168 | 0.0422 | 0.2748 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0049 | 0.0014 | 0.0012 |
Brugia malayi | MH1 domain containing protein | 0.0111 | 0.0226 | 0.0221 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0126 | 0.028 | 0.2867 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0047 | 0.0005 | 0.0003 |
Brugia malayi | MH1 domain containing protein | 0.02 | 0.0536 | 0.0531 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.081 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0674 | 0.2172 | 0.2168 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0093 | 0.0166 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0014 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0213 | 0.0581 | 0.1994 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.0574 |
Schistosoma mansoni | Smad4 | 0.009 | 0.0153 | 0.0515 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0093 | 0.0166 | 0.0556 |
Giardia lamblia | Kinase, PLK | 0.0091 | 0.0159 | 0.5 |
Brugia malayi | hypothetical protein | 0.1265 | 0.4209 | 0.4206 |
Loa Loa (eye worm) | hypothetical protein | 0.1265 | 0.4209 | 0.4206 |
Brugia malayi | MH2 domain containing protein | 0.02 | 0.0536 | 0.0531 |
Schistosoma mansoni | phosphatidylinositol-4-phosphate 5-kinase type II | 0.0163 | 0.0408 | 0.1396 |
Brugia malayi | nuclear receptor NHR-88 | 0.0093 | 0.0166 | 0.0161 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0047 | 0.0005 | 0.0063 |
Schistosoma mansoni | smad | 0.02 | 0.0536 | 0.1839 |
Schistosoma mansoni | coup transcription factor | 0.0093 | 0.0166 | 0.0559 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0166 | 0.0161 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0421 | 0.1298 | 0.1293 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0049 | 0.0014 | 0.003 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0091 | 0.0159 | 0.0154 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0093 | 0.0166 | 0.0161 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0091 | 0.0159 | 0.0016 |
Brugia malayi | hypothetical protein | 0.0148 | 0.0355 | 0.035 |
Echinococcus multilocularis | GPCR, family 2 | 0.0213 | 0.0581 | 0.1991 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0126 | 0.028 | 0.1808 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.009 | 0.0153 | 0.0209 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0093 | 0.0166 | 0.0556 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0213 | 0.0581 | 0.1991 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0093 | 0.0166 | 0.0559 |
Brugia malayi | Isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.0574 |
Schistosoma mansoni | nuclear hormone receptor | 0.0093 | 0.0166 | 0.0559 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0884 | 0.2894 | 0.2891 |
Trichomonas vaginalis | glutaminase, putative | 0.0283 | 0.0821 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0283 | 0.0821 | 0.0816 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 0.5 |
Loa Loa (eye worm) | nuclear factor I | 0.0111 | 0.0226 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.048 | 0.0475 |
Brugia malayi | Pip kinase protein 2 | 0.0163 | 0.0408 | 0.0403 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0159 | 0.1942 |
Brugia malayi | hypothetical protein | 0.0081 | 0.0125 | 0.012 |
Brugia malayi | hypothetical protein | 0.0126 | 0.028 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.0166 | 0.0161 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0319 | 0.0944 | 0.3251 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 1 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0319 | 0.0944 | 0.1326 |
Brugia malayi | nuclear receptor RXR | 0.0049 | 0.0014 | 0.0009 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.009 | 0.0153 | 0.0209 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.02 | 0.0536 | 0.0531 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0091 | 0.0159 | 0.0218 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.02 | 0.0536 | 0.1836 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0093 | 0.0166 | 0.0161 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0126 | 0.028 | 0.1808 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0159 | 0.1942 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.02 | 0.0536 | 0.0749 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0421 | 0.1298 | 0.1825 |
Schistosoma mansoni | Smad4 | 0.009 | 0.0153 | 0.0515 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.0355 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0126 | 0.028 | 0.0275 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0486 | 0.1523 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0093 | 0.0166 | 0.0559 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0213 | 0.0581 | 0.1991 |
Echinococcus granulosus | phosphatidylinositol 5 phosphate 4 kinase type 2 | 0.0163 | 0.0408 | 0.0568 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.2942 | 1 | 1 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.1988 |
Brugia malayi | ecdysteroid receptor | 0.0093 | 0.0166 | 0.0161 |
Brugia malayi | isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.0574 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0319 | 0.0944 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0093 | 0.0166 | 0.0161 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0014 | 0.0009 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.02 | 0.0536 | 0.1839 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.02 | 0.0536 | 0.1836 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0213 | 0.0579 | 0.3779 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0184 | 0.048 | 0.0475 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0093 | 0.0166 | 0.0031 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0091 | 0.0159 | 0.0534 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0093 | 0.0166 | 0.0161 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0093 | 0.0166 | 0.0559 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0093 | 0.0166 | 0.0161 |
Schistosoma mansoni | thyroid hormone receptor | 0.0093 | 0.0166 | 0.0559 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0126 | 0.028 | 0.1808 |
Loa Loa (eye worm) | hypothetical protein | 0.0674 | 0.2172 | 0.2168 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0091 | 0.0159 | 0.0537 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0159 | 0.1942 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.009 | 0.0153 | 0.0148 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0126 | 0.028 | 0.1808 |
Loa Loa (eye worm) | hypothetical protein | 0.0486 | 0.1523 | 0.1519 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0093 | 0.0166 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0014 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0328 | 0.0976 | 0.3362 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0093 | 0.0166 | 0.0161 |
Schistosoma mansoni | hypothetical protein | 0.0148 | 0.0355 | 0.1213 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0213 | 0.0579 | 0.3779 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0184 | 0.048 | 0.0807 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.0355 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0283 | 0.0821 | 0.0816 |
Schistosoma mansoni | tar DNA-binding protein | 0.0884 | 0.2894 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0093 | 0.0166 | 0.0227 |
Brugia malayi | MH2 domain containing protein | 0.009 | 0.0153 | 0.0148 |
Schistosoma mansoni | smad | 0.009 | 0.0153 | 0.0515 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 0.5 |
Echinococcus granulosus | Smad4 | 0.02 | 0.0536 | 0.0749 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0093 | 0.0166 | 0.0161 |
Brugia malayi | glutaminase DH11.1 | 0.0283 | 0.0821 | 0.0816 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0319 | 0.0944 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0421 | 0.1298 | 0.4474 |
Brugia malayi | Smad1 | 0.02 | 0.0536 | 0.0531 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0014 | 0.0009 |
Entamoeba histolytica | hypothetical protein | 0.0148 | 0.0355 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0486 | 0.1523 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0159 | 0.1942 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.02 | 0.0536 | 0.0531 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.02 | 0.0536 | 0.0749 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0213 | 0.0581 | 0.0812 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0091 | 0.0159 | 0.1942 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0093 | 0.0166 | 0.0161 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0093 | 0.0166 | 0.0227 |
Schistosoma mansoni | thyroid hormone receptor | 0.0093 | 0.0166 | 0.0559 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.007 ug ml-1 | Inhibitory concentration against Hepatitis B virus reverse transcriptase (HBV-RT) | ChEMBL. | 12217361 |
Inhibition (binding) | = 52 % | Inhibitory activity against Hepatitis B virus reverse transcriptase (HBV-RT) at 0.01 ug/mL | ChEMBL. | 12217361 |
Inhibition (binding) | = 69 % | Inhibitory activity against Hepatitis B virus reverse transcriptase (HBV-RT) at 0.1 ug/mL | ChEMBL. | 12217361 |
Inhibition (binding) | = 84 % | Inhibitory activity against Hepatitis B virus reverse transcriptase (HBV-RT) at 1 ug/mL | ChEMBL. | 12217361 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.