Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0122 | 0.0218 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0377 | 0.0377 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0236 | 0.0421 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0053 | 0.0754 | 0.1345 |
Echinococcus multilocularis | Protein lozenge | 0.0062 | 0.0936 | 0.1763 |
Onchocerca volvulus | Putative lipoyltransferase 2, mitochondrial | 0.0026 | 0.0182 | 0.0182 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.0402 | 0.0757 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0665 | 0.0665 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0377 | 0.0377 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0157 | 0.2932 | 0.5523 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0377 | 0.0261 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0618 | 0.1102 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0875 | 0.0875 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0377 | 0.0673 |
Echinococcus granulosus | N terminal of biotin protein ligase | 0.0122 | 0.2202 | 0.4148 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0043 | 0.055 | 0.2755 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0182 | 0.0182 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0047 | 0.0618 | 0.0618 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0377 | 0.0377 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.027 | 0.5309 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.2712 | 0.2712 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0236 | 0.0445 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0377 | 0.0261 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0236 | 0.0406 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0377 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0377 | 0.0377 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0236 | 0.0406 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0377 | 0.0377 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0618 | 0.0618 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0053 | 0.0754 | 0.142 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0948 | 0.1786 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0754 | 0.0754 |
Brugia malayi | lipoate-protein ligase, mitochondrial precursor, putative | 0.0026 | 0.0182 | 0.0182 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0618 | 0.1102 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0754 | 0.0754 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0377 | 0.071 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.005 | 0.0682 | 0.1154 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0377 | 0.0244 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.005 | 0.0682 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0377 | 0.0261 |
Brugia malayi | lipoate-protein ligase B containing protein | 0.0026 | 0.0182 | 0.0182 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0471 | 0.0888 |
Chlamydia trachomatis | hypothetical protein | 0.0122 | 0.2202 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.2712 | 0.2712 |
Onchocerca volvulus | 0.0035 | 0.0377 | 0.0377 | |
Mycobacterium leprae | POSSIBLE BIFUNCTIONAL PROTEIN BirA: BIOTIN OPERON REPRESSOR + BIOTIN--[ACETYL-COA-CARBOXYLASE] SYNTHETASE (BIOTIN--PROTEIN LIGAS | 0.0063 | 0.0972 | 1 |
Plasmodium falciparum | biotin protein ligase, putative | 0.0089 | 0.1518 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0377 | 0.0377 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0043 | 0.055 | 0.2448 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 1 | 1 |
Plasmodium vivax | biotin--[acetyl-CoA-carboxylase] synthetase, putative | 0.0089 | 0.1518 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0377 | 0.0244 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0377 | 0.0451 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0212 | 0.4102 | 1 |
Trypanosoma cruzi | Biotin--acetyl-CoA-carboxylase ligase, putative | 0.0089 | 0.1518 | 0.3409 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0212 | 0.4102 | 1 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0123 | 0.2221 | 0.4183 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.005 | 0.0682 | 0.1284 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0053 | 0.0754 | 0.142 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0184 | 0.3506 | 0.6604 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0402 | 0.0717 |
Brugia malayi | Bromodomain containing protein | 0.0077 | 0.1263 | 0.1263 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.1022 | 0.1823 |
Echinococcus granulosus | octanoyltransferase mitochondrial | 0.0026 | 0.0182 | 0.0343 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0377 | 0.0377 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0053 | 0.0754 | 0.142 |
Onchocerca volvulus | 0.0492 | 1 | 1 | |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0377 | 0.3906 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0232 | 0.0232 |
Echinococcus multilocularis | biotin protein ligase | 0.0089 | 0.1518 | 0.286 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.005 | 0.0682 | 0.3741 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0558 | 0.0558 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0377 | 0.0377 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0377 | 0.0451 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0061 | 0.0061 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0377 | 0.0451 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0236 | 0.0236 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.005 | 0.0682 | 0.1154 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0972 | 0.0972 |
Entamoeba histolytica | biotin--acetyl-CoA-carboxylase ligase, putative | 0.0089 | 0.1518 | 0.2726 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0376 | 0.0708 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0377 | 0.0244 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0212 | 0.4102 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0377 | 0.0498 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0046 | 0.0602 | 0.1133 |
Echinococcus multilocularis | octanoyltransferase, mitochondrial | 0.0026 | 0.0182 | 0.0343 |
Echinococcus multilocularis | zinc finger protein | 0.0023 | 0.0122 | 0.023 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0377 | 0.0244 |
Loa Loa (eye worm) | acetyltransferase | 0.0163 | 0.3076 | 0.3076 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.2712 | 0.5108 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0377 | 0.2471 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0377 | 0.0261 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0377 | 0.071 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0362 | 0.0683 |
Onchocerca volvulus | 0.0047 | 0.0618 | 0.0618 | |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.0402 | 0.0402 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.025 | 0.0447 |
Schistosoma mansoni | lozenge | 0.0062 | 0.0936 | 0.1669 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0471 | 0.0888 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 0.1602 | 0.3017 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.0402 | 0.0717 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0377 | 0.2471 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0212 | 0.4102 | 0.4102 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0236 | 0.0236 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0236 | 0.0421 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0053 | 0.0754 | 0.142 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0618 | 0.1164 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.3921 | 0.3921 |
Brugia malayi | jmjC domain containing protein | 0.0093 | 0.1602 | 0.1602 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.2712 | 0.5108 |
Schistosoma mansoni | biotin-protein ligase | 0.0122 | 0.2202 | 0.3928 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0228 | 0.0429 |
Onchocerca volvulus | 0.0232 | 0.4513 | 0.4513 | |
Trypanosoma cruzi | Biotin--acetyl-CoA-carboxylase ligase, putative | 0.0089 | 0.1518 | 0.3409 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0377 | 0.0673 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0377 | 0.0377 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.005 | 0.0682 | 1 |
Wolbachia endosymbiont of Brugia malayi | biotin-(acetyl-CoA carboxylase) ligase | 0.0089 | 0.1518 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.1198 | 0.2137 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0377 | 0.0244 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0377 | 0.1461 |
Mycobacterium tuberculosis | Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (biotin--protein ligas | 0.0063 | 0.0972 | 0.0986 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0058 | 0.0866 | 0.0889 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0236 | 0.0445 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.01 | 0.0178 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.025 | 0.0447 |
Treponema pallidum | biotin--acetyl-CoA-carboxylase ligase | 0.0407 | 0.8201 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0284 | 0.5607 | 1 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.027 | 0.5309 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.4861 | 0.4861 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0426 | 0.0426 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0377 | 0.0451 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0602 | 0.1073 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0212 | 0.4102 | 0.7726 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0618 | 0.1102 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0754 | 0.0754 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0618 | 0.1164 |
Giardia lamblia | Hypothetical protein | 0.0089 | 0.1518 | 1 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0618 | 0.1164 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0377 | 0.0244 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0236 | 0.0236 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0377 | 0.0377 |
Echinococcus granulosus | 5'partial|biotin protein ligase | 0.0063 | 0.0972 | 0.1832 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0236 | 0.1085 |
Onchocerca volvulus | Lipoyltransferase 1, mitochondrial homolog | 0.0026 | 0.0182 | 0.0182 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0163 | 0.3076 | 0.5794 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.025 | 0.1373 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.3921 | 0.3921 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0377 | 0.0377 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.0402 | 0.0402 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0368 | 0.0368 |
Echinococcus granulosus | zinc finger protein | 0.0023 | 0.0122 | 0.023 |
Loa Loa (eye worm) | biotin protein ligase 1 | 0.0089 | 0.1518 | 0.1518 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0236 | 0.1085 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0602 | 0.0602 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0212 | 0.4102 | 0.7726 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0046 | 0.0602 | 0.1133 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0134 | 0.2461 | 0.2461 |
Onchocerca volvulus | 0.0029 | 0.025 | 0.025 | |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0377 | 0.0261 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.0368 | 0.0693 |
Echinococcus multilocularis | biotin protein ligase | 0.0089 | 0.1518 | 0.286 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0618 | 0.0618 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0212 | 0.4102 | 1 |
Loa Loa (eye worm) | runx1 | 0.0062 | 0.0936 | 0.0936 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.2712 | 0.2712 |
Brugia malayi | biotin--acetyl-CoA-carboxylase ligase family protein | 0.0089 | 0.1518 | 0.1518 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0248 | 0.4861 | 0.4861 |
Onchocerca volvulus | 0.0035 | 0.0377 | 0.0377 | |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 1 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0163 | 0.3076 | 0.5486 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0948 | 0.1786 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.4513 | 1 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0212 | 0.4102 | 0.7316 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0618 | 0.0618 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0597 | 0.0597 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.01 | 0.0188 |
Schistosoma mansoni | biotin-protein ligase | 0.0089 | 0.1518 | 0.2708 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0046 | 0.0602 | 0.1073 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0377 | 0.0244 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0212 | 0.4102 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0377 | 0.0498 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.2712 | 0.5108 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.01 | 0.0188 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0618 | 0.1164 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Brugia malayi | MH2 domain containing protein | 0.0134 | 0.2461 | 0.2461 |
Mycobacterium ulcerans | bifunctional protein BirA | 0.0381 | 0.7655 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0376 | 0.0708 |
Echinococcus granulosus | peregrin | 0.0035 | 0.0368 | 0.0693 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.025 | 0.025 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0122 | 0.2202 | 0.4652 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0061 | 0.0108 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0377 | 0.0244 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.025 | 0.0514 |
Schistosoma mansoni | lipoate-protein ligase B | 0.0026 | 0.0182 | 0.0324 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0021 | 0.0083 | 0.0083 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0225 | 0.4372 | 0.5225 |
Leishmania major | biotin/lipoate protein ligase-like protein | 0.0089 | 0.1518 | 0.3409 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0508 | 0.0508 |
Onchocerca volvulus | 0.0035 | 0.0377 | 0.0377 | |
Echinococcus granulosus | transcription factor Dp 1 | 0.0123 | 0.2221 | 0.4183 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0377 | 0.0498 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0058 | 0.0866 | 0.0889 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0377 | 0.0244 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0134 | 0.2461 | 0.2461 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0184 | 0.3506 | 0.6604 |
Trypanosoma brucei | Biotin--acetyl-CoA-carboxylase ligase, putative | 0.0089 | 0.1518 | 0.3409 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.025 | 0.0472 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0377 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0377 | 0.0377 |
Plasmodium falciparum | biotin--acetyl-CoA-carboxylase, putative | 0.0089 | 0.1518 | 1 |
Echinococcus multilocularis | N terminal of biotin protein ligase | 0.0122 | 0.2202 | 0.4148 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0377 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0972 | 0.0972 |
Chlamydia trachomatis | biotin synthetase | 0.0089 | 0.1518 | 0.6615 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0163 | 0.3076 | 0.3076 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1092 | 0.1092 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 0.1602 | 0.3017 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0618 | 0.0618 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0212 | 0.4102 | 0.4102 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0377 | 0.0451 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 311 uM l-1 | Inhibition of histamine release from sensitized rat mast cells in vitro | ChEMBL. | 6183427 |
ID50 (functional) | = 0.6 uM kg-1 | Inhibition of rat passive cutaneous anaphylaxis (PCA) reaction after intravenous administration | ChEMBL. | 6183427 |
ID50 (functional) | > 100 uM kg-1 | Inhibition of rat passive cutaneous anaphylaxis(PCA) reaction was determined after oral administration | ChEMBL. | 6183427 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.