Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0012 | 0.139 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0082 | 0.1521 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0032 | 0.0089 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0067 | 0.03 | 0.5604 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0116 | 0.0183 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0252 | 0.1404 | 0.1404 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0067 | 0.03 | 0.1465 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | nuclear receptor RXR | 0.0035 | 0.0111 | 0.0174 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0111 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0019 |
Schistosoma mansoni | patched 1 | 0.0045 | 0.0168 | 0.3144 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0021 | 0.0022 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0067 | 0.03 | 0.0471 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.0021 | 0.0022 | 0.5 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0035 | 0.0111 | 0.0543 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.005 | 0.0079 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0105 | 0.0526 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0105 | 0.0526 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0067 | 0.03 | 0.0471 |
Schistosoma mansoni | DNA ligase IV | 0.0021 | 0.0022 | 0.0415 |
Onchocerca volvulus | 0.0032 | 0.0089 | 0.0104 | |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0207 | 0.3855 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0217 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0019 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0067 | 0.03 | 0.0437 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0217 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0168 | 0.0264 |
Brugia malayi | nuclear hormone receptor | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0067 | 0.03 | 0.0471 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0045 | 0.0168 | 0.0822 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0032 | 0.0089 | 0.1654 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0032 | 0.0089 | 0.0139 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0031 | 0.0082 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.03 | 0.0471 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0116 | 0.2174 |
Schistosoma mansoni | nuclear receptor | 0.0032 | 0.0089 | 0.1654 |
Onchocerca volvulus | Bile acid receptor homolog | 0.1087 | 0.6379 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0067 | 0.03 | 0.0471 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0032 | 0.0089 | 0.0432 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0067 | 0.03 | 0.0471 |
Schistosoma mansoni | survival motor neuron protein | 0.0051 | 0.0207 | 0.3855 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0067 | 0.03 | 0.0471 |
Echinococcus multilocularis | nibrin | 0.0021 | 0.0022 | 0.0022 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0067 | 0.03 | 0.5604 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0129 | 0.211 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0021 | 0.0022 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0035 | 0.0111 | 0.2077 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0032 | 0.0089 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0111 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.03 | 0.0471 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0032 | 0.0089 | 0.0139 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0129 | 0.211 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0045 | 0.0168 | 0.0264 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.005 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0067 | 0.03 | 0.03 |
Schistosoma mansoni | nuclear hormone receptor | 0.0032 | 0.0089 | 0.1654 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0035 | 0.0111 | 0.0111 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0105 | 0.0526 | 0.2567 |
Brugia malayi | hypothetical protein | 0.0252 | 0.1404 | 0.2201 |
Chlamydia trachomatis | DNA ligase | 0.0021 | 0.0022 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0252 | 0.1404 | 0.6851 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0032 | 0.0089 | 0.0432 |
Brugia malayi | nuclear receptor RXR | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0021 | 0.0022 | 0.0035 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0067 | 0.03 | 0.03 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0067 | 0.03 | 0.03 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0021 | 0.0022 | 0.0000026221 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0051 | 0.0207 | 0.0324 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0032 | 0.0089 | 0.1654 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0021 | 0.0022 | 0.0109 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0032 | 0.0089 | 0.0089 |
Onchocerca volvulus | 0.0242 | 0.1343 | 0.2077 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.005 | 0.5 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0021 | 0.0022 | 0.0000026221 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0021 | 0.0022 | 0.0035 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0067 | 0.03 | 0.5604 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0526 | 0.0825 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.005 | 0.0079 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0067 | 0.03 | 0.5604 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0032 | 0.0089 | 0.0089 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.0111 | 0.0174 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0067 | 0.03 | 0.03 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0082 | 0.1521 |
Brugia malayi | steroid hormone receptor | 0.0067 | 0.03 | 0.0471 |
Loa Loa (eye worm) | DR-78 | 0.0032 | 0.0089 | 0.0139 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0045 | 0.0168 | 0.1107 |
Treponema pallidum | DNA ligase (lig) | 0.0021 | 0.0022 | 0.5 |
Echinococcus multilocularis | tumor protein p63 | 0.0361 | 0.205 | 0.205 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0067 | 0.03 | 0.1465 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0129 | 0.211 |
Schistosoma mansoni | thyroid hormone receptor | 0.0067 | 0.03 | 0.5604 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.005 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0107 | 0.0536 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0067 | 0.03 | 0.0471 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0129 | 0.2399 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.015 | 0.0795 | 0.3878 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.1168 | 0.183 |
Brugia malayi | ecdysteroid receptor | 0.1087 | 0.6379 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0067 | 0.03 | 0.03 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0067 | 0.03 | 0.5604 |
Trichomonas vaginalis | set domain proteins, putative | 0.0242 | 0.1343 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0067 | 0.03 | 0.0471 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0021 | 0.0022 | 0.0000026221 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0159 | 0.2963 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0067 | 0.03 | 0.0471 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0067 | 0.03 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.005 | 0.0079 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | nuclear hormone receptor | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0067 | 0.03 | 0.0471 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0067 | 0.03 | 0.0471 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.005 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0067 | 0.03 | 0.0471 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0032 | 0.0089 | 0.0089 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0032 | 0.0089 | 0.0104 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0067 | 0.03 | 0.03 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.1168 | 0.183 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0021 | 0.0022 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0082 | 0.1521 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.005 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0082 | 0.1521 |
Brugia malayi | conserved hypotetical protein | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0032 | 0.0089 | 0.0139 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0032 | 0.0089 | 0.0432 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0082 | 0.0128 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.005 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0159 | 0.2963 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0067 | 0.03 | 0.0471 |
Echinococcus multilocularis | protein patched | 0.0045 | 0.0168 | 0.0168 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.005 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0214 | 0.0336 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0032 | 0.0089 | 0.0139 |
Schistosoma mansoni | coup transcription factor | 0.0067 | 0.03 | 0.5604 |
Onchocerca volvulus | 0.0067 | 0.03 | 0.0437 | |
Brugia malayi | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0067 | 0.03 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.1087 | 0.6379 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0116 | 0.0183 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0067 | 0.03 | 0.0471 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0067 | 0.03 | 0.5604 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0111 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | topoisomerase | 0.0021 | 0.0022 | 0.0035 |
Onchocerca volvulus | 0.0051 | 0.0207 | 0.029 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0111 | 0.0174 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.005 | 1 |
Brugia malayi | tailless protein | 0.0032 | 0.0089 | 0.0139 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0053 | 0.0214 | 0.4 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.005 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0159 | 0.2963 |
Echinococcus granulosus | nibrin | 0.0021 | 0.0022 | 0.0109 |
Schistosoma mansoni | nuclear receptor | 0.0032 | 0.0089 | 0.1654 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0021 | 0.0022 | 0.0416 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0082 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.005 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0032 | 0.0089 | 0.1654 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.03 | 0.0471 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0045 | 0.0168 | 0.0822 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0217 | 0.034 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.005 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0067 | 0.03 | 0.5604 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0035 | 0.0111 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Echinococcus multilocularis | protein dispatched 1 | 0.0051 | 0.0206 | 0.0206 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0067 | 0.03 | 0.1465 |
Echinococcus granulosus | FTZ F1 alpha | 0.0067 | 0.03 | 0.1465 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0067 | 0.03 | 0.1465 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0032 | 0.0089 | 0.0432 |
Schistosoma mansoni | thyroid hormone receptor | 0.0067 | 0.03 | 0.5604 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0217 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.005 | 0.0079 |
Giardia lamblia | Replication factor C, subunit 1 | 0.0021 | 0.0022 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0082 | 0.0128 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0032 | 0.0089 | 0.0139 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.015 | 0.0795 | 0.0795 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0067 | 0.03 | 0.1465 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0129 | 0.211 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0111 | 0.0174 |
Brugia malayi | nuclear receptor NHR-67 | 0.0032 | 0.0089 | 0.0139 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0067 | 0.03 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0111 | 0.0174 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0067 | 0.03 | 0.1465 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0067 | 0.03 | 0.0471 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.0111 | 0.0174 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.005 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.005 | 0.056 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.005 | 0.0079 |
Echinococcus multilocularis | expressed conserved protein | 0.0099 | 0.0488 | 0.0488 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | DKFZp564C0469 protein | 0.0021 | 0.0022 | 0.0035 |
Onchocerca volvulus | 0.0053 | 0.0214 | 0.0302 | |
Plasmodium vivax | replication factor C subunit 1, putative | 0.0021 | 0.0022 | 0.1433 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0032 | 0.0089 | 0.0139 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0129 | 0.2399 |
Brugia malayi | CHE-14 protein | 0.0045 | 0.0168 | 0.0264 |
Echinococcus granulosus | tumor protein p63 | 0.0361 | 0.205 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 0.1404 | 0.2201 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.005 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Schistosoma mansoni | topbp1 | 0.0021 | 0.0022 | 0.0415 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0067 | 0.03 | 0.03 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.005 | 0.0079 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0067 | 0.03 | 0.0471 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0075 | 0.0365 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0021 | 0.0022 | 0.5 |
Echinococcus granulosus | expressed conserved protein | 0.0099 | 0.0488 | 0.2381 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.0021 | 0.0022 | 0.2597 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0067 | 0.03 | 0.03 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0045 | 0.0168 | 0.0168 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0111 | 0.0174 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0021 | 0.0022 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0021 | 0.0022 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0082 | 0.0082 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0129 | 0.0202 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0129 | 0.0129 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Onchocerca volvulus | 0.0031 | 0.0082 | 0.0093 | |
Onchocerca volvulus | 0.0032 | 0.0089 | 0.0104 | |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0082 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.005 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0032 | 0.0089 | 0.0432 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0031 | 0.0082 | 0.0082 |
Schistosoma mansoni | topbp1 | 0.0021 | 0.0022 | 0.0415 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.0021 | 0.0022 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.03 | 0.0471 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0067 | 0.03 | 0.5604 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0021 | 0.0022 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0012 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0067 | 0.03 | 0.5604 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0032 | 0.0089 | 0.0104 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0021 | 0.0022 | 0.0000068726 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.005 | 0.056 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0129 | 0.0627 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0159 | 0.2963 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0032 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0067 | 0.03 | 0.0471 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0067 | 0.03 | 0.0471 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0032 | 0.0089 | 0.1654 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0105 | 0.0526 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0067 | 0.03 | 0.0471 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0067 | 0.03 | 0.1465 |
Schistosoma mansoni | nuclear hormone receptor | 0.0032 | 0.0089 | 0.1654 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0067 | 0.03 | 0.0471 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0032 | 0.0089 | 0.0432 |
Onchocerca volvulus | 0.0025 | 0.005 | 0.0044 | |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0067 | 0.03 | 0.5604 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0032 | 0.0089 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0229 | 0.0359 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0035 | 0.0111 | 0.2077 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.005 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0032 | 0.0089 | 0.0089 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.005 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0022 | 0.0035 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0067 | 0.03 | 0.1465 |
Brugia malayi | ecdysone receptor | 0.0032 | 0.0089 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0089 | 0.0139 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] | ChEMBL. | No reference |
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.