Detailed information for compound 1497300

Basic information

Technical information
  • TDR Targets ID: 1497300
  • Name: N-[2-(4-chlorophenyl)ethyl]-3-imidazo[5,4-b]p yridin-3-yl-2-methylbenzamide
  • MW: 390.865 | Formula: C22H19ClN4O
  • H donors: 1 H acceptors: 3 LogP: 4.59 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)CCNC(=O)c1cccc(c1C)n1cnc2c1nccc2
  • InChi: 1S/C22H19ClN4O/c1-15-18(22(28)25-13-11-16-7-9-17(23)10-8-16)4-2-6-20(15)27-14-26-19-5-3-12-24-21(19)27/h2-10,12,14H,11,13H2,1H3,(H,25,28)
  • InChiKey: WWXHEEWTKQEWBX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[2-(4-chlorophenyl)ethyl]-3-imidazo[5,4-b]pyridin-3-yl-2-methyl-benzamide
  • N-[2-(4-chlorophenyl)ethyl]-3-(3-imidazo[5,4-b]pyridinyl)-2-methylbenzamide
  • E760-7013
  • NCGC00125355-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens flap structure-specific endonuclease 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania donovani flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus multilocularis flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Echinococcus granulosus flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Cryptosporidium parvum flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania infantum flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Plasmodium vivax flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Cryptosporidium hominis flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium falciparum flap endonuclease 1 Get druggable targets OG5_127472 All targets in OG5_127472
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Trypanosoma brucei gambiense flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania braziliensis flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Brugia malayi Flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Trichomonas vaginalis flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Neospora caninum flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum ko:K04799 flap endonuclease-1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania major flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Entamoeba histolytica Flap nuclease, putative Get druggable targets OG5_127472 All targets in OG5_127472
Babesia bovis XPG N-terminal domain and XPG I-region domain containing protein Get druggable targets OG5_127472 All targets in OG5_127472
Schistosoma mansoni flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium yoelii flap endonuclease-1-related Get druggable targets OG5_127472 All targets in OG5_127472
Trypanosoma congolense flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Leishmania mexicana flap endonuclease-1 (FEN-1), putative Get druggable targets OG5_127472 All targets in OG5_127472
Toxoplasma gondii flap structure-specific endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium berghei flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Giardia lamblia Flap structure-specific endonuclease Get druggable targets OG5_127472 All targets in OG5_127472
Theileria parva flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Plasmodium knowlesi flap endonuclease 1, putative Get druggable targets OG5_127472 All targets in OG5_127472
Loa Loa (eye worm) flap endonuclease-1 Get druggable targets OG5_127472 All targets in OG5_127472
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei exonuclease, putative flap structure-specific endonuclease 1 380 aa 322 aa 24.5 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum cysteine proteinase falcipain 1 0.0105 0.032 0.2375
Trypanosoma cruzi cruzipain precursor, putative 0.016 0.0546 0.1798
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0632 0.063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.002 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Leishmania major cathepsin L-like protease 0.0113 0.0353 0.3484
Loa Loa (eye worm) jmjC domain-containing protein 0.0181 0.063 0.0699
Schistosoma mansoni microtubule-associated protein tau 0.136 0.5447 0.5446
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0432 0.1655 0.6448
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0051 0.032
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0083 0.0193
Plasmodium falciparum basic transcription factor 3b, putative 0.0069 0.0172 0.1256
Giardia lamblia Cathepsin B precursor 0.0272 0.1001 1
Echinococcus multilocularis insulin receptor 0.0718 0.2823 0.2822
Plasmodium vivax serine-repeat antigen (SERA) 0.0052 0.0103 0.0726
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0067 0.0065
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0113 0.0353 0.0351
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1861
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Entamoeba histolytica cysteine proteinase, putative 0.006 0.0136 0.1298
Onchocerca volvulus Cathepsin F homolog 0.0113 0.0353 0.0927
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0052 0.0339
Leishmania major cathepsin L-like protease 0.0113 0.0353 0.3484
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0066 0.0159 0.1156
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0062 0.0143 0.1375
Brugia malayi cathepsin F-like cysteine proteinase 0.0053 0.0109 0.0118
Toxoplasma gondii heat shock protein HSP90 0.0093 0.027 0.1992
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0159 0.5834
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0272 0.1001 1
Schistosoma mansoni hypothetical protein 0.0091 0.0265 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0049 0.0089
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.005 0.0094 0.0092
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0066 0.0159 0.1533
Schistosoma mansoni cathepsin F (C01 family) 0.0113 0.0353 0.0351
Plasmodium falciparum heat shock protein 90, putative 0.0054 0.0111 0.0792
Trichomonas vaginalis heat shock protein, putative 0.0087 0.0246 0.0471
Trypanosoma cruzi major cysteine proteinase, putative 0.0052 0.0103 0.0319
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0007 0.0008
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0031 0.0017 0.008
Loa Loa (eye worm) hypothetical protein 0.0229 0.0828 0.0918
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0062 0.0143 0.0371
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0041 0.022
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0083 0.0193
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0373 0.1415 0.1413
Trypanosoma brucei Heat shock protein 83, putative 0.0093 0.027 0.2644
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0058 0.0129 0.0127
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0052 0.0103 0.0101
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0052 0.0103 0.0726
Plasmodium vivax heat shock protein 86, putative 0.0093 0.027 0.1994
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0432 0.1655 0.6448
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0041 0.0262
Brugia malayi glutathione reductase 0.0189 0.0664 0.0735
Giardia lamblia Cathepsin B precursor 0.0272 0.1001 1
Echinococcus granulosus heat shock protein 0.0093 0.027 0.0268
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0114
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0172 0.0328
Giardia lamblia Cathepsin B precursor 0.0052 0.0103 0.0843
Schistosoma mansoni cathepsin F (C01 family) 0.0113 0.0353 0.0351
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0103 0.0101
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.003 0.0012 0.0017
Echinococcus multilocularis endoplasmin 0.0087 0.0246 0.0244
Echinococcus granulosus Immunoglobulin 0.0029 0.0009 0.0007
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0041 0.0205
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0103 0.0193
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Plasmodium falciparum glutathione reductase 0.0066 0.0159 0.1156
Loa Loa (eye worm) hypothetical protein 0.0053 0.0109 0.0121
Loa Loa (eye worm) hypothetical protein 0.0247 0.09 0.0998
Giardia lamblia Cathepsin B precursor 0.0052 0.0103 0.0843
Schistosoma mansoni cathepsin s 0.0053 0.0109 0.0107
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0151 0.0165
Loa Loa (eye worm) fibroinase 0.0113 0.0353 0.0392
Schistosoma mansoni cpg binding protein 0.0195 0.0688 0.0686
Schistosoma mansoni heat shock protein 0.0093 0.027 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0051 0.0352
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.1067 0.4098
Trypanosoma brucei transcription factor BTF3, putative 0.0069 0.0172 0.1665
Trypanosoma brucei PAB1-binding protein , putative 0.0074 0.0196 0.1899
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0082 0.024
Brugia malayi cathepsin B-like cysteine proteinase 0.0763 0.3008 0.3335
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0172 0.0191
Onchocerca volvulus 0.0113 0.0353 0.0927
Leishmania major cathepsin L-like protease 0.016 0.0546 0.5427
Brugia malayi acetyltransferase, GNAT family protein 0.0159 0.0542 0.0599
Onchocerca volvulus Cathepsin L homolog 0.0052 0.0103 0.0265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0083 0.0768
Brugia malayi Cathepsin L-like precursor 0.0113 0.0353 0.039
Brugia malayi Cathepsin L-like precursor 0.0113 0.0353 0.039
Entamoeba histolytica cysteine protease, putative 0.0052 0.0103 0.0925
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0037 0.0009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0083 0.0709
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0052 0.0103 0.0726
Echinococcus multilocularis muscleblind protein 0.015 0.0503 0.0501
Echinococcus granulosus PHD finger protein rhinoceros 0.0088 0.0249 0.0247
Brugia malayi Papain family cysteine protease containing protein 0.0113 0.0353 0.039
Echinococcus granulosus histone acetyltransferase MYST2 0.0107 0.0328 0.0326
Loa Loa (eye worm) TK/FAK protein kinase 0.0808 0.3191 0.354
Toxoplasma gondii exonuclease III APE 0.0037 0.0041 0.0262
Trypanosoma brucei heat shock protein 90, putative 0.0093 0.027 0.2644
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0008
Schistosoma mansoni hypothetical protein 0.008 0.0216 0.0214
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Loa Loa (eye worm) hypothetical protein 0.006 0.0136 0.0151
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.0216 0.024
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0094 0.0275 0.0273
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.032 0.3356
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0411 0.0409
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0052 0.0103 0.0726
Brugia malayi cathepsin L-like precursor 0.006 0.0136 0.0148
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0035
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0041 0.0046
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0087 0.0246 0.0887
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0103 0.0101
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0024 0.004
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0083 0.009
Loa Loa (eye worm) CXXC zinc finger family protein 0.0174 0.0601 0.0667
Mycobacterium tuberculosis Probable dehydrogenase 0.0432 0.1655 0.6448
Plasmodium vivax unspecified product 0.0105 0.032 0.2375
Brugia malayi cathepsin L precursor 0.0052 0.0103 0.0112
Entamoeba histolytica cysteine protease, putative 0.0052 0.0103 0.0925
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0839 0.3319 0.3681
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0041 0.0075
Trypanosoma brucei heat shock protein 84, putative 0.0062 0.0143 0.1367
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0038 0.0048 0.0046
Loa Loa (eye worm) MH2 domain-containing protein 0.0352 0.1327 0.1472
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0275 0.0273
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Echinococcus multilocularis chromobox protein 1 0.0069 0.0172 0.017
Loa Loa (eye worm) glutathione reductase 0.0189 0.0664 0.0737
Schistosoma mansoni protein phosphatase 2C 0.0028 0.0007 0.0005
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0172 0.0552
Brugia malayi PHD-finger family protein 0.0162 0.0554 0.0613
Trypanosoma brucei trypanothione reductase 0.0189 0.0664 0.6614
Giardia lamblia Heat shock protein HSP 90-alpha 0.0093 0.027 0.2547
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0151 0.0167
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0114
Plasmodium vivax vivapain-1 0.0105 0.032 0.2375
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Echinococcus granulosus phd:f box containing protein 0.0028 0.0007 0.0005
Loa Loa (eye worm) TK/EGFR protein kinase 0.2234 0.9016 1
Giardia lamblia Cathepsin B precursor 0.0052 0.0103 0.0843
Schistosoma mansoni phd/f-box containing protein 0.0028 0.0007 0.0005
Trypanosoma cruzi cysteine peptidase, putative 0.016 0.0546 0.1798
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0039 0.0052 0.0339
Giardia lamblia Cathepsin L precursor 0.0052 0.0103 0.0843
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.0103 0.0114
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0082 0.0089
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0083 0.0193
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0048 0.0088 0.0096
Plasmodium vivax ataxin-2 like protein, putative 0.0074 0.0196 0.1432
Schistosoma mansoni hypothetical protein 0.0072 0.0186 0.0184
Toxoplasma gondii Hsp90 domain-containing protein 0.0351 0.1325 0.9993
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Giardia lamblia Cathepsin L-like protease 0.0052 0.0103 0.0843
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0066 0.0159 0.1533
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0066 0.0159 0.1156
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0083 0.009
Trypanosoma cruzi trypanothione reductase, putative 0.0189 0.0664 0.2191
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0124 0.0396 0.2951
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Echinococcus granulosus insulin receptor 0.0718 0.2823 0.2822
Loa Loa (eye worm) hypothetical protein 0.0053 0.0109 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Onchocerca volvulus 0.0113 0.0353 0.0927
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Trypanosoma cruzi cysteine proteinase, putative 0.0105 0.032 0.1043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0107 0.0329 0.1074
Plasmodium falciparum serine repeat antigen 1 0.0052 0.0103 0.0726
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0225 0.0812 0.081
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Schistosoma mansoni heat shock protein 0.0062 0.0143 0.0141
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.032 0.3356
Loa Loa (eye worm) thioredoxin reductase 0.0189 0.0664 0.0737
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Brugia malayi beta-NAC-like protein 0.0069 0.0172 0.0189
Schistosoma mansoni bromodomain containing protein 0.0391 0.149 0.1489
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0172 0.0552
Loa Loa (eye worm) hypothetical protein 0.015 0.0503 0.0558
Brugia malayi chromobox protein homolog 3 0.0039 0.0049 0.0052
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0002
Schistosoma mansoni tyrosine kinase 0.2234 0.9016 0.9015
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0052 0.0103 0.0114
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0103 0.0101
Loa Loa (eye worm) hypothetical protein 0.015 0.0505 0.056
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0114
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0203 0.0201
Echinococcus granulosus zinc finger protein 0.013 0.0424 0.0422
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0914 1
Echinococcus multilocularis cysteine protease 0.0113 0.0353 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0103 0.0193
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0114
Echinococcus granulosus protein kinase c iota type 0.0286 0.1061 0.1059
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0083 0.0193
Brugia malayi Endoplasmin precursor 0.0093 0.027 0.0297
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0272 0.1001 0.0999
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0066 0.0159 0.1156
Echinococcus multilocularis epidermal growth factor receptor 0.2234 0.9016 0.9015
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0041 0.0077
Schistosoma mansoni jumonji domain containing protein 0.0028 0.0007 0.0005
Echinococcus multilocularis SAM and MBT domain containing protein 0.0094 0.0275 0.0273
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0066 0.0159 0.0174
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0037 0.0035
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0066 0.0159 0.5834
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.037 0.1403 0.1401
Brugia malayi Bromodomain containing protein 0.0461 0.1776 0.1969
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0041 0.0039
Brugia malayi hypothetical protein 0.0298 0.111 0.1229
Toxoplasma gondii histone lysine methyltransferase SET1 0.0351 0.1326 1
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0029 0.0009 0.0007
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0718 0.2823 0.2822
Echinococcus multilocularis cysteine protease 0.0113 0.0353 0.0351
Schistosoma mansoni hypothetical protein 0.0123 0.0395 0.0393
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0087 0.0246 0.0887
Schistosoma mansoni transcription factor btf3 0.0069 0.0172 0.017
Schistosoma mansoni hypothetical protein 0.1693 0.6808 0.6807
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Schistosoma mansoni inositol monophosphatase 0.0036 0.0037 0.0035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.032 0.3149
Onchocerca volvulus 0.0113 0.0353 0.0927
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.048 0.1852 0.7226
Brugia malayi mbt repeat family protein 0.0094 0.0275 0.0303
Echinococcus multilocularis zinc finger protein 0.013 0.0424 0.0422
Brugia malayi Cathepsin L-like precursor 0.006 0.0136 0.0148
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.002 0.0098
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0052 0.0103 0.0726
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0652 0.2554 1
Onchocerca volvulus Cathepsin L homolog 0.0113 0.0353 0.0927
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0052 0.0103 0.0101
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0029 0.0008 0.0011
Entamoeba histolytica heat shock protein 90, putative 0.0093 0.027 0.2795
Echinococcus multilocularis Immunoglobulin 0.0029 0.0009 0.0007
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0275 0.0273
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0083 0.0768
Echinococcus granulosus lysine specific demethylase 5A 0.0127 0.0411 0.0409
Onchocerca volvulus 0.0113 0.0353 0.0927
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.005 0.0094 0.0092
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.032 0.3356
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0718 0.2823 0.2822
Brugia malayi PHD-finger family protein 0.005 0.0095 0.0104
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.048 0.1852 0.7226
Echinococcus granulosus jumonji domain containing protein 0.0122 0.0389 0.0387
Echinococcus multilocularis protein tyrosine kinase 0.0799 0.3153 0.3152
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0141 0.0467 0.5002
Echinococcus multilocularis phd:f box containing protein 0.0028 0.0007 0.0005
Plasmodium falciparum heat shock protein 90, putative 0.0351 0.1325 1
Echinococcus multilocularis neuropeptide receptor A26 0.0456 0.1754 0.1753
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1861
Loa Loa (eye worm) transcription factor SMAD2 0.0352 0.1327 0.1472
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0186 0.0184
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.001
Toxoplasma gondii NAC domain-containing protein 0.0069 0.0172 0.1255
Schistosoma mansoni cathepsin B (C01 family) 0.0052 0.0103 0.0101
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0107 0.0328 0.0326
Trypanosoma cruzi heat shock protein 85, putative 0.0093 0.027 0.0876
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0215 0.0768 0.0766
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0029 0.0009 0.0007
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0083 0.0242
Schistosoma mansoni tyrosine kinase 0.0718 0.2823 0.2822
Echinococcus granulosus Protein kinase C brain isozyme 0.0043 0.0067 0.0065
Echinococcus granulosus tumor protein p63 0.0339 0.1274 0.1272
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0051 0.0337
Echinococcus multilocularis GPCR, family 2 0.008 0.0216 0.0214
Giardia lamblia PHD finger protein 15 0.0088 0.0249 0.2337
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0041 0.0027
Loa Loa (eye worm) hypothetical protein 0.0074 0.0196 0.0217
Trypanosoma cruzi cysteine protease, putative 0.0105 0.032 0.1043
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0041 0.0115
Onchocerca volvulus 0.006 0.0136 0.0353
Trichomonas vaginalis mercuric reductase, putative 0.0066 0.0159 0.0302
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Plasmodium falciparum serine repeat antigen 2 0.0052 0.0103 0.0726
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0052 0.0103 0.0193
Schistosoma mansoni bromodomain containing protein 0.0039 0.0051 0.0049
Brugia malayi Calcitonin receptor-like protein seb-1 0.0251 0.0919 0.1017
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.001
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0083 0.0768
Loa Loa (eye worm) hypothetical protein 0.0225 0.0812 0.0901
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0103 0.0101
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0066 0.0159 0.0494
Brugia malayi cathepsin Z-like cysteine proteinase 0.0052 0.0103 0.0112
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0057 0.0124 0.0885
Loa Loa (eye worm) acetyltransferase 0.0159 0.0542 0.0601
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Brugia malayi Hsp90 protein 0.0062 0.0143 0.0156
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0083 0.0242
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.037 0.1403 0.1401
Onchocerca volvulus 0.003 0.0012 0.0026
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0103 0.0112
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0159 0.0542 0.054
Schistosoma mansoni cell adhesion molecule 0.0038 0.0048 0.0046
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0107 0.0328 0.0361
Onchocerca volvulus 0.0298 0.111 0.2925
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Onchocerca volvulus 0.0113 0.0353 0.0927
Loa Loa (eye worm) heat shock protein 75 0.0062 0.0143 0.0158
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0105 0.032 0.0318
Echinococcus multilocularis protein kinase c iota type 0.0286 0.1061 0.1059
Echinococcus granulosus cpg binding protein 0.0195 0.0688 0.0686
Leishmania major cathepsin L-like protease 0.0113 0.0353 0.3484
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Trichomonas vaginalis heat shock protein, putative 0.0067 0.0166 0.0315
Brugia malayi Protein kinase domain containing protein 0.0808 0.3191 0.3538
Schistosoma mansoni hypothetical protein 0.008 0.0216 0.0214
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0287 0.1063 0.1061
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0058 0.0129 0.0127
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0005
Brugia malayi MH2 domain containing protein 0.0352 0.1327 0.147
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0101
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0033 0.0028 0.0026
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Echinococcus multilocularis jumonji domain containing protein 0.0122 0.0389 0.0387
Echinococcus granulosus heat shock protein 90 0.0079 0.0215 0.0213
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0151 0.0149
Echinococcus granulosus cathepsin b 0.0763 0.3008 0.3006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Brugia malayi Immunoglobulin I-set domain containing protein 0.0485 0.1871 0.2073
Schistosoma mansoni tyrosine kinase 0.0035 0.0035 0.0033
Echinococcus granulosus muscleblind protein 0.015 0.0503 0.0501
Echinococcus granulosus microtubule associated protein 2 0.136 0.5447 0.5446
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0268 0.0984 0.3801
Schistosoma mansoni atypical protein kinase C 0.0304 0.1134 0.1132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0103 0.0193
Loa Loa (eye worm) hypothetical protein 0.0172 0.0594 0.0658
Schistosoma mansoni tyrosine kinase 0.1203 0.4805 0.4804
Echinococcus multilocularis 0.069 0.2708 0.2707
Schistosoma mansoni tyrosine kinase 0.1184 0.4729 0.4728
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0114
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0103 0.0193
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0105 0.032 0.0318
Giardia lamblia Grp94/Hsp90 0.0087 0.0246 0.231
Brugia malayi Heterochromatin protein 1 0.0069 0.0172 0.0189
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0124 0.0396 0.0394
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.0508
Loa Loa (eye worm) hypothetical protein 0.0039 0.0051 0.0056
Echinococcus granulosus jumonji domain containing 1A 0.0028 0.0007 0.0005
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.0508
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0083 0.0242
Echinococcus multilocularis lysine specific demethylase 6a 0.0028 0.0007 0.0005
Brugia malayi cathepsin L-like cysteine proteinase 0.0052 0.0103 0.0112
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0083 0.0193
Giardia lamblia Hypothetical protein 0.0052 0.0103 0.0843
Trypanosoma cruzi cysteine peptidase, putative 0.0113 0.0353 0.1154
Plasmodium falciparum phd finger protein, putative 0.0088 0.0249 0.1837
Toxoplasma gondii heat shock protein 75, putative 0.0062 0.0143 0.103
Mycobacterium ulcerans heat shock protein 90 0.0087 0.0246 0.0841
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0041 0.0242
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0002 0.0002
Onchocerca volvulus 0.0174 0.0601 0.1581
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Brugia malayi Inositol-1 0.0036 0.0037 0.0039
Plasmodium vivax glutathione reductase, putative 0.0189 0.0664 0.4987
Loa Loa (eye worm) hypothetical protein 0.0038 0.0048 0.0053
Echinococcus granulosus endoplasmin 0.0087 0.0246 0.0244
Echinococcus granulosus cathepsin L 0.0105 0.032 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0082 0.0252
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.025 0.0914 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0099 0.0296 0.0963
Echinococcus multilocularis cathepsin b 0.0763 0.3008 0.3006
Echinococcus multilocularis histone acetyltransferase MYST2 0.0107 0.0328 0.0326
Loa Loa (eye worm) hypothetical protein 0.0763 0.3008 0.3336
Loa Loa (eye worm) hypothetical protein 0.006 0.0136 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0103 0.0193
Treponema pallidum fructose-bisphosphate aldolase 0.0141 0.0467 1
Giardia lamblia Cathepsin L precursor 0.0052 0.0103 0.0843
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0061 0.0112
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0082 0.0761
Plasmodium falciparum serine repeat antigen 4 0.0052 0.0103 0.0726
Loa Loa (eye worm) hypothetical protein 0.0251 0.0919 0.1019
Giardia lamblia Cathepsin B precursor 0.0052 0.0103 0.0843
Giardia lamblia Cathepsin B precursor 0.0272 0.1001 1
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Trypanosoma cruzi trypanothione reductase, putative 0.0066 0.0159 0.0508
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0052 0.0103 0.0843
Loa Loa (eye worm) MBCTL1 0.0107 0.0328 0.0364
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0181 0.0632 0.0699
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0037 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Leishmania major basic transcription factor 3a, putative 0.0069 0.0172 0.1665
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.0216 0.0214
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0052 0.0103 0.0101
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0052 0.0103 0.0726
Echinococcus granulosus histone acetyltransferase KAT2B 0.0057 0.0124 0.0122
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0249 0.1836
Echinococcus granulosus cathepsin l1 0.006 0.0136 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0052 0.0103 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Schistosoma mansoni tyrosine kinase 0.1203 0.4805 0.4804
Loa Loa (eye worm) hypothetical protein 0.0113 0.0353 0.0392
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0151 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0103 0.0193
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.0216 0.0214
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0088 0.0249 0.0247
Plasmodium falciparum endoplasmin, putative 0.0067 0.0166 0.1207
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0251 0.0919 0.1017
Loa Loa (eye worm) hypothetical protein 0.0268 0.0987 0.1095
Plasmodium falciparum glutathione reductase 0.0189 0.0664 0.4987
Plasmodium falciparum zinc finger protein, putative 0.0032 0.0022 0.0113
Plasmodium falciparum thioredoxin reductase 0.0189 0.0664 0.4987
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0186 0.0184
Brugia malayi Protein kinase domain containing protein 0.0718 0.2823 0.313
Schistosoma mansoni tyrosine kinase 0.1184 0.4729 0.4728
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0052 0.0103 0.0726
Plasmodium vivax thioredoxin reductase, putative 0.0189 0.0664 0.4987
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0066 0.0159 0.1533
Echinococcus granulosus geminin 0.1693 0.6808 0.6807
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0632 0.063
Leishmania major cathepsin L-like protease 0.0113 0.0353 0.3484
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0007 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0082 0.0252
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0033 0.0024 0.0022
Echinococcus multilocularis protein kinase c epsilon type 0.0043 0.0067 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0103 0.0193
Echinococcus multilocularis Immunoglobulin 0.0029 0.0009 0.0007
Loa Loa (eye worm) RNA binding protein 0.0063 0.0151 0.0167
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.0508
Leishmania major hypothetical protein, conserved 0.0074 0.0196 0.1899
Plasmodium falciparum serine repeat antigen 9 0.0052 0.0103 0.0726
Schistosoma mansoni hypothetical protein 0.0029 0.0008 0.0006
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0494
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0048 0.0086 0.0084
Echinococcus multilocularis PHD finger protein rhinoceros 0.0088 0.0249 0.0247
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0052 0.0103 0.0112
Loa Loa (eye worm) inositol-1 0.0036 0.0037 0.0041
Trypanosoma cruzi cruzipain precursor, putative 0.0053 0.0109 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0251 0.0919 0.1019
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0052 0.0103 0.0726
Treponema pallidum NADH oxidase 0.0066 0.0159 0.2768
Schistosoma mansoni chromobox protein 0.0069 0.0172 0.017
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0763 0.3008 0.3006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0225 0.0812 0.081
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0041 0.0262
Schistosoma mansoni myst-related protein 0.0032 0.0022 0.002
Plasmodium vivax endoplasmin, putative 0.0093 0.027 0.1994
Echinococcus multilocularis peregrin 0.0105 0.0321 0.0319
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Echinococcus multilocularis cathepsin L 0.0052 0.0103 0.0101
Loa Loa (eye worm) hypothetical protein 0.008 0.0216 0.024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0103 0.0193
Brugia malayi Pre-SET motif family protein 0.0839 0.3319 0.368
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0043 0.0067 0.0075
Schistosoma mansoni ap endonuclease 0.0037 0.0041 0.0039
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0082 0.008
Brugia malayi jmjC domain containing protein 0.0287 0.1063 0.1177
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0035 0.0212
Loa Loa (eye worm) hypothetical protein 0.0052 0.0103 0.0114
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0067 0.0065
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0196 0.0629
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0157
Plasmodium falciparum serine repeat antigen 7 0.0052 0.0103 0.0726
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Schistosoma mansoni methyl-cpg binding protein mbd 0.0102 0.0307 0.0305
Giardia lamblia Cysteine protease 0.0052 0.0103 0.0843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.032 0.0613
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0083 0.0193
Trypanosoma cruzi cysteine proteinase, putative 0.0105 0.032 0.1043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Trichomonas vaginalis set domain proteins, putative 0.0954 0.379 0.7322
Trichomonas vaginalis glucosylceramidase, putative 0.0895 0.3545 0.6848
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Brugia malayi protein kinase C3,putative 0.0262 0.096 0.1063
Loa Loa (eye worm) hypothetical protein 0.0088 0.0249 0.0276
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.002 0.0022
Trypanosoma brucei ISWI complex protein 0.0091 0.0265 0.2593
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0145 0.0482 0.048
Brugia malayi fibroinase precursor 0.0052 0.0103 0.0112
Schistosoma mansoni SET domain protein 0.003 0.0012 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.0508
Trypanosoma brucei heat shock protein 90, putative 0.0093 0.027 0.2644
Echinococcus granulosus histone acetyltransferase KAT2B 0.0141 0.0468 0.0466
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0103 0.0193
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0305
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Entamoeba histolytica transcription factor BTF3, putative 0.0069 0.0172 0.1707
Schistosoma mansoni tyrosine kinase 0.0718 0.2823 0.2822
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0052 0.0103 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0109 0.034
Entamoeba histolytica hypothetical protein 0.0069 0.0172 0.1707
Echinococcus multilocularis roundabout 2 0.0046 0.0078 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0135 0.0442 0.044
Echinococcus granulosus peregrin 0.0105 0.0321 0.0319
Brugia malayi hypothetical protein 0.0074 0.0196 0.0215
Loa Loa (eye worm) hypothetical protein 0.025 0.0914 0.1014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.004 0.0038
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0061 0.0155
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0052 0.0103 0.0925
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0082 0.0574
Entamoeba histolytica heat shock protein 90, putative 0.0093 0.027 0.2795
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0052 0.0103 0.0726
Schistosoma mansoni jumonji/arid domain-containing protein 0.0127 0.0411 0.0409
Leishmania major cathepsin L-like protease 0.016 0.0546 0.5427
Echinococcus granulosus transcription factor btf3 0.0069 0.0172 0.017
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0033 0.0024 0.0022
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0159 0.0508
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0113 0.0353 0.0392
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0105 0.032 0.1043
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0189 0.0664 0.2538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Loa Loa (eye worm) hypothetical protein 0.005 0.0094 0.0104
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0113 0.0353 0.0677
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Echinococcus granulosus neuropeptide receptor A26 0.0456 0.1754 0.1753
Echinococcus granulosus epidermal growth factor receptor 0.1203 0.4805 0.4804
Plasmodium falciparum cysteine proteinase falcipain 3 0.0113 0.0353 0.2627
Echinococcus granulosus lysine specific demethylase 6a 0.0028 0.0007 0.0005
Echinococcus granulosus roundabout 2 0.0046 0.0078 0.0076
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0005
Leishmania major cathepsin L-like protease 0.016 0.0546 0.5427
Toxoplasma gondii thioredoxin reductase 0.0189 0.0664 0.4984
Brugia malayi hypothetical protein 0.0072 0.0186 0.0204
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.001
Brugia malayi SET domain containing protein 0.003 0.0012 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0115 0.0363 0.0361
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0763 0.3008 0.3006
Loa Loa (eye worm) ctsf protein 0.0113 0.0353 0.0392
Plasmodium falciparum thioredoxin reductase 0.0066 0.0159 0.1156
Loa Loa (eye worm) hypothetical protein 0.0053 0.0109 0.0121
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Trichomonas vaginalis glucosylceramidase, putative 0.0895 0.3545 0.6848
Giardia lamblia Cathepsin L precursor 0.0052 0.0103 0.0843
Mycobacterium ulcerans hypothetical protein 0.0047 0.0083 0.0193
Toxoplasma gondii NADPH-glutathione reductase 0.0066 0.0159 0.1155
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0632 0.063
Echinococcus granulosus histone lysine methyltransferase setb 0.0225 0.0812 0.081
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0052 0.0103 0.0843
Echinococcus multilocularis polycomb protein SCMH1 0.0094 0.0275 0.0273
Echinococcus granulosus heat shock protein 90 0.0093 0.027 0.0268
Trichomonas vaginalis glutathione reductase, putative 0.0066 0.0159 0.0302
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0066 0.0159 0.1156
Toxoplasma gondii cathepsin CPC1 0.0052 0.0103 0.0725
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.032 0.3149
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0082 0.008
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0763 0.3008 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0102 0.0307 0.0305
Brugia malayi F/Y-rich N-terminus family protein 0.0098 0.029 0.0319
Echinococcus multilocularis neuropeptide s receptor 0.0456 0.1754 0.1753
Loa Loa (eye worm) TK/INSR protein kinase 0.0718 0.2823 0.3132
Plasmodium falciparum serine repeat antigen 6 0.0052 0.0103 0.0726
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0159 0.0542 0.054
Onchocerca volvulus 0.0047 0.0083 0.0214
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0041 0.0075
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0159 0.1533
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0124 0.0396 0.0394
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0035 0.0051
Loa Loa (eye worm) bromodomain containing protein 0.0109 0.0337 0.0374
Echinococcus granulosus flap endonuclease 1 0.0031 0.002 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0028 0.0007 0.0008
Giardia lamblia Cathepsin L precursor 0.0052 0.0103 0.0843
Echinococcus multilocularis thioredoxin glutathione reductase 0.0189 0.0664 0.0663
Loa Loa (eye worm) endoplasmin 0.0093 0.027 0.0299
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0272 0.1001 0.193
Trypanosoma cruzi heat shock protein 85, putative 0.0093 0.027 0.0876
Entamoeba histolytica cysteine protease, putative 0.0052 0.0103 0.0925
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Plasmodium vivax heat shock protein 90, putative 0.0062 0.0143 0.1031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.032 0.0613
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Schistosoma mansoni ap endonuclease 0.0037 0.0041 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0038
Trypanosoma cruzi ISWI complex protein 0.0091 0.0265 0.0859
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0172 0.0328
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0035 0.0212
Loa Loa (eye worm) hypothetical protein 0.0107 0.0328 0.0364
Brugia malayi cathepsin F-like cysteine proteinase 0.0052 0.0103 0.0112
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0485 0.1871 0.2075
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0652 0.2554 1
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.1067 0.4098
Echinococcus multilocularis neuroglian 0.0036 0.0039 0.0037
Echinococcus multilocularis muscleblind protein 1 0.015 0.0503 0.0501
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Schistosoma mansoni zinc finger protein 0.0091 0.0265 0.0263
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.002 0.0043
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Trichomonas vaginalis helicase, putative 0.0039 0.0052 0.0095
Onchocerca volvulus 0.0954 0.379 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0141 0.0467 0.5002
Brugia malayi Cathepsin L-like precursor 0.006 0.0136 0.0148
Entamoeba histolytica cysteine protease, putative 0.0113 0.0353 0.3729
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0062 0.0143 0.0141
Leishmania major heat shock protein, putative 0.0062 0.0143 0.1367
Schistosoma mansoni hypothetical protein 0.2475 1 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0066 0.0159 0.1155
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0041 0.0348
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0079 0.0215 0.0213
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Echinococcus granulosus mixed lineage leukemia protein mll 0.0048 0.0086 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0037 0.0193
Plasmodium falciparum heat shock protein 90 0.0093 0.027 0.1994
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0052 0.0103 0.0726
Trypanosoma cruzi cysteine peptidase, putative 0.016 0.0546 0.1798
Echinococcus granulosus SAM and MBT domain containing protein 0.0094 0.0275 0.0273
Trichomonas vaginalis endoplasmin, putative 0.0067 0.0166 0.0315
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0049 0.0089
Trypanosoma cruzi PAB1-binding protein , putative 0.0074 0.0196 0.0629
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0113 0.0353 0.0351
Schistosoma mansoni vesicular amine transporter 0.0029 0.0009 0.0007
Brugia malayi mbt repeat family protein 0.0094 0.0275 0.0303
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Echinococcus granulosus neuroglian 0.0036 0.0039 0.0037
Mycobacterium tuberculosis Probable oxidoreductase 0.048 0.1852 0.7226
Brugia malayi Bromodomain containing protein 0.0105 0.0321 0.0354
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0052 0.0103 0.0193
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0033 0.0028 0.0026
Schistosoma mansoni endoplasmin 0.0093 0.027 0.0268
Brugia malayi Cathepsin L-like precursor 0.0113 0.0353 0.039
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0432 0.1655 0.6448
Schistosoma mansoni chromobox protein 0.0069 0.0172 0.017
Giardia lamblia Encystation-specific protease 0.0052 0.0103 0.0843
Schistosoma mansoni cathepsin C 0.0052 0.0103 0.0101
Entamoeba histolytica hypothetical protein 0.0032 0.0022 0.0021
Toxoplasma gondii cathepsin CPL 0.0113 0.0353 0.2625
Schistosoma mansoni hypothetical protein 0.0088 0.0249 0.0247
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.002 0.0099
Plasmodium vivax unspecified product 0.0053 0.0109 0.0773
Echinococcus multilocularis epidermal growth factor receptor 0.1203 0.4805 0.4804
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0103 0.0112
Mycobacterium tuberculosis Probable reductase 0.0432 0.1655 0.6448
Brugia malayi RNA binding protein 0.0063 0.0151 0.0165
Plasmodium falciparum serine repeat antigen 8 0.0052 0.0103 0.0726
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Onchocerca volvulus 0.0094 0.0275 0.072
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.032 0.3356
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0092
Onchocerca volvulus Tyrosine kinase homolog 0.0454 0.1744 0.46
Plasmodium vivax vivapain-2 0.0113 0.0353 0.2627
Loa Loa (eye worm) PHD-finger family protein 0.0123 0.0395 0.0438
Brugia malayi jmjC domain containing protein 0.0028 0.0007 0.0005
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0092
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.001
Brugia malayi Flap endonuclease-1 0.0031 0.002 0.002
Brugia malayi AF-10 protein 0.0029 0.0008 0.0007
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0145 0.0482 0.048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0652 0.2554 1
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0305
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0048 0.0088 0.0096
Schistosoma mansoni hypothetical protein 0.0033 0.0028 0.0026
Plasmodium vivax serine-repeat antigen (SERA) 0.0052 0.0103 0.0726
Brugia malayi hypothetical protein 0.0029 0.0009 0.0008
Leishmania major cysteine peptidase A (CPA) 0.0113 0.0353 0.3484
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0632 0.063
Onchocerca volvulus 0.0113 0.0353 0.0927
Loa Loa (eye worm) hypothetical protein 0.0029 0.0009 0.001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Echinococcus granulosus cathepsin l1 0.0113 0.0353 0.0351
Echinococcus multilocularis cathepsin b 0.0763 0.3008 0.3006
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.1294 0.5176 0.5741
Loa Loa (eye worm) cysteine protease 0.0113 0.0353 0.0392
Brugia malayi Pre-SET motif family protein 0.0124 0.0396 0.0437
Schistosoma mansoni hypothetical protein 0.0172 0.0594 0.0592
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0052 0.0103 0.0726
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0066 0.0159 0.1533
Schistosoma mansoni flap endonuclease-1 0.0028 0.0007 0.0005
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0763 0.3008 0.3006
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0377 0.1433 0.1431
Echinococcus multilocularis cpg binding protein 0.0195 0.0688 0.0686
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0083 0.0709
Plasmodium falciparum serine repeat antigen 3 0.0052 0.0103 0.0726
Echinococcus multilocularis lysine specific demethylase 5A 0.0106 0.0324 0.0322
Brugia malayi Muscleblind-like protein 0.015 0.0503 0.0555
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.1294 0.5176 0.574
Schistosoma mansoni tyrosine kinase 0.0799 0.3153 0.3152
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0048 0.0086 0.0084
Giardia lamblia Cathepsin B precursor 0.0052 0.0103 0.0843
Loa Loa (eye worm) hypothetical protein 0.0422 0.1617 0.1794
Trypanosoma brucei heat shock protein, putative 0.0093 0.027 0.2644
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0432 0.1655 0.6448
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Toxoplasma gondii heat shock protein 90, putative 0.0093 0.027 0.1992
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0113 0.0353 0.0392
Loa Loa (eye worm) hypothetical protein 0.0298 0.111 0.1231
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0057 0.0124 0.0233
Echinococcus granulosus cathepsin b 0.0763 0.3008 0.3006
Onchocerca volvulus 0.0135 0.0442 0.1162
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0066 0.0159 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0632 0.063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0052 0.0103 0.0726
Schistosoma mansoni cpg binding protein 0.0195 0.0688 0.0686
Plasmodium vivax vivapain-3 0.0105 0.032 0.2375
Echinococcus granulosus twitchin 0.0037 0.0041 0.0039
Trypanosoma cruzi heat shock protein 85, putative 0.0079 0.0215 0.0694
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0082 0.0574
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0103 0.0193
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.0216 0.0238
Trypanosoma cruzi heat shock protein 90, putative 0.0079 0.0215 0.0694
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Echinococcus multilocularis cathepsin L 0.0105 0.032 0.0318
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Schistosoma mansoni hypothetical protein 0.0578 0.2253 0.2251
Onchocerca volvulus 0.0113 0.0353 0.0927
Echinococcus multilocularis flap endonuclease 1 0.0031 0.002 0.0018
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0113 0.0353 0.2627
Loa Loa (eye worm) mbt repeat family protein 0.0094 0.0275 0.0305
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0082 0.008
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0249 0.1837
Brugia malayi Cathepsin L-like precursor 0.0053 0.0109 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.0066
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0041 0.0039
Brugia malayi Papain family cysteine protease containing protein 0.0052 0.0103 0.0112
Trypanosoma cruzi heat shock protein 90, putative 0.0093 0.027 0.0876
Plasmodium vivax vivapain-2 0.0113 0.0353 0.2627
Plasmodium falciparum flap endonuclease 1 0.0031 0.002 0.0099
Entamoeba histolytica cysteine protease, putative 0.0052 0.0103 0.0925
Echinococcus multilocularis tumor protein p63 0.0339 0.1274 0.1272
Brugia malayi Furin-like cysteine rich region family protein 0.2234 0.9016 1
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Loa Loa (eye worm) ICD-1 protein 0.0069 0.0172 0.0191
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0103 0.0193
Trypanosoma cruzi heat shock protein 85, putative 0.0093 0.027 0.0876
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0113 0.0353 0.2627
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0136 0.0257
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0057 0.0124 0.0885
Schistosoma mansoni heat shock protein 0.0093 0.027 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0046 0.0078 0.0086
Trypanosoma brucei cysteine peptidase C (CPC) 0.0272 0.1001 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0053 0.0109 0.0118
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0272 0.1001 0.3313
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.0216 0.0214
Schistosoma mansoni phosphatidylserine receptor 0.0028 0.0007 0.0005
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0067 0.0065
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0157
Leishmania major cathepsin L-like protease 0.0113 0.0353 0.3484
Onchocerca volvulus 0.0428 0.1639 0.432
Brugia malayi isocitrate dehydrogenase 0.0047 0.0082 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0037 0.023
Schistosoma mansoni cathepsin F (C01 family) 0.006 0.0136 0.0134
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0377 0.1433 0.1431
Echinococcus granulosus epidermal growth factor receptor 0.2234 0.9016 0.9015
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0094 0.0092
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0052 0.0103 0.0101
Trypanosoma cruzi heat shock protein, putative 0.0062 0.0143 0.0453
Onchocerca volvulus Cathepsin L homolog 0.0113 0.0353 0.0927
Brugia malayi CXXC zinc finger family protein 0.0174 0.0601 0.0665
Entamoeba histolytica cysteine protease, putative 0.0052 0.0103 0.0925
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0196 0.1432
Echinococcus multilocularis jumonji domain containing 1A 0.0028 0.0007 0.0005
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Echinococcus multilocularis heat shock protein 0.0093 0.027 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0052 0.0103 0.0193
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0028 0.0007 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0353 0.3729
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0033 0.0024 0.0022
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0052 0.0103 0.0193
Schistosoma mansoni myst-related protein 0.0032 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.006 0.0136 0.0151
Brugia malayi CHD4 protein 0.0033 0.0024 0.0025
Giardia lamblia Hypothetical protein 0.0052 0.0103 0.0843
Echinococcus granulosus protein tyrosine kinase 0.0799 0.3153 0.3152
Giardia lamblia NADH oxidase lateral transfer candidate 0.0066 0.0159 0.1421
Giardia lamblia Fructose-bisphosphate aldolase 0.0141 0.0467 0.4559
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0141 0.0467 0.0897
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0082 0.0574
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0008 0.0015
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.0216 0.0214
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0029 0.0009 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Brugia malayi latrophilin 2 splice variant baaae 0.0172 0.0594 0.0656
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0041 0.0348
Echinococcus granulosus protein kinase c epsilon type 0.0043 0.0067 0.0065
Giardia lamblia Cysteine protease 0.0052 0.0103 0.0843
Loa Loa (eye worm) cathepsin B 0.0272 0.1001 0.111
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0038
Trypanosoma cruzi ISWI complex protein 0.0091 0.0265 0.0859
Toxoplasma gondii cathepsin CPC2 0.0052 0.0103 0.0725
Plasmodium falciparum ataxin-2 like protein, putative 0.0074 0.0196 0.1432
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0107 0.0328 0.0326
Schistosoma mansoni tyrosine kinase 0.1184 0.4729 0.4728
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.1533
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.0508
Echinococcus multilocularis cathepsin L cysteine protease 0.0113 0.0353 0.0351
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0105 0.032 0.0318
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0083 0.0242
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0094 0.0275 0.072
Giardia lamblia Cysteine protease 0.0052 0.0103 0.0843
Echinococcus granulosus tar DNA binding protein 0.0063 0.0151 0.0149
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0037 0.0101
Brugia malayi Papain family cysteine protease containing protein 0.0105 0.032 0.0353
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0052 0.0103 0.0101
Echinococcus granulosus GPCR family 2 0.008 0.0216 0.0214
Trichomonas vaginalis heat shock protein, putative 0.0054 0.0111 0.021
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0066 0.0159 0.0543
Toxoplasma gondii LsmAD domain-containing protein 0.0074 0.0196 0.1431
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0082 0.0092
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.048 0.1852 0.7226
Entamoeba histolytica cysteine proteinase 2 0.0105 0.032 0.3356
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0092
Brugia malayi Thioredoxin reductase 0.0189 0.0664 0.0735
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0052 0.0103 0.0726
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0041 0.0044
Plasmodium vivax SET domain protein, putative 0.0124 0.0396 0.2953
Echinococcus granulosus cathepsin L cysteine protease 0.0105 0.032 0.0318
Echinococcus multilocularis cathepsin L cysteine protease 0.0113 0.0353 0.0351
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.1533
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0172 0.0328
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0432 0.1655 0.6448
Echinococcus granulosus neuropeptide s receptor 0.0456 0.1754 0.1753
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0632 0.063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0113 0.0353 0.0677
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0052 0.0103 0.0843
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0083 0.0709
Echinococcus granulosus JmjC domain containing protein 4 0.0028 0.0007 0.0005
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0048 0.0086 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0066 0.0159 0.1533
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.006 0.0136 0.0257
Echinococcus multilocularis microtubule associated protein 2 0.136 0.5447 0.5446
Echinococcus granulosus methyl CpG binding domain protein 2 0.0102 0.0307 0.0305
Schistosoma mansoni nephrin 0.0036 0.0039 0.0037
Echinococcus multilocularis heat shock protein 90 0.0093 0.027 0.0268
Brugia malayi hypothetical protein 0.0048 0.0088 0.0095
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0029 0.0008 0.0015
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0082 0.0574
Schistosoma mansoni myelin transcription factor 1 myt1 0.0107 0.0328 0.0326
Schistosoma mansoni jumonji domain containing protein 0.0228 0.0822 0.082
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0083 0.0193
Leishmania major hypothetical protein, conserved 0.0091 0.0265 0.2593
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0172 0.0328
Echinococcus granulosus raf serine:threonine protein kinase 0.0036 0.004 0.0038
Brugia malayi PHD-finger family protein 0.0088 0.0249 0.0274
Brugia malayi Papain family cysteine protease containing protein 0.0105 0.032 0.0353
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0078 0.0086
Plasmodium falciparum serine repeat antigen 5 0.0052 0.0103 0.0726
Loa Loa (eye worm) hypothetical protein 0.0039 0.0049 0.0054
Onchocerca volvulus 0.0052 0.0103 0.0265
Echinococcus granulosus chromobox protein 1 0.0069 0.0172 0.017
Toxoplasma gondii preprocathepsin c precursor, putative 0.0052 0.0103 0.0725
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0057 0.0124 0.0885
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0066 0.0159 0.0508
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.1203 0.4805 0.4804
Loa Loa (eye worm) histone methyltransferase 0.0058 0.0129 0.0143
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0225 0.0812 0.081
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0082 0.0761
Loa Loa (eye worm) jmjC domain-containing protein 0.0127 0.0411 0.0456
Giardia lamblia Cathepsin L precursor 0.0052 0.0103 0.0843
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.002 0.0131
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0037 0.0066
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0087 0.0246 0.2411
Echinococcus multilocularis transcription factor btf3 0.0069 0.0172 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0052 0.0103 0.0193
Brugia malayi Cathepsin L-like precursor 0.0113 0.0353 0.039
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0103 0.0193
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0066 0.0159 0.0157
Giardia lamblia Cathepsin L precursor 0.0052 0.0103 0.0843
Trichomonas vaginalis heat shock protein, putative 0.0093 0.027 0.0516
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.0109 0.0121
Trypanosoma cruzi cysteine peptidase, putative 0.016 0.0546 0.1798
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0083 0.009
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0052 0.0103 0.0843
Brugia malayi protein kinase C II. 0.0043 0.0067 0.0072
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0008 0.0011
Onchocerca volvulus Alhambra homolog 0.0088 0.0249 0.0652
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0061 0.0112
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0181 0.0632 0.0701
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0087 0.0246 1
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.005 0.0143
Entamoeba histolytica cysteine proteinase 1, putative 0.0105 0.032 0.3356
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0011 0.0009
Echinococcus granulosus cathepsin l cysteine peptidase 0.0113 0.0353 0.0351
Entamoeba histolytica cysteine proteinase, putative 0.0113 0.0353 0.3729
Plasmodium vivax basic transcription factor 3b, putative 0.0069 0.0172 0.1256
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0052 0.0103 0.0925
Treponema pallidum heat shock protein 90 0.0087 0.0246 0.4817
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0113 0.0353 0.0677
Brugia malayi heat shock protein 90 0.0093 0.027 0.0297
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0151 0.0149
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Echinococcus granulosus polycomb protein SCMH1 0.0094 0.0275 0.0273
Loa Loa (eye worm) CHromoDomain protein family member 0.0033 0.0024 0.0027
Schistosoma mansoni hypothetical protein 0.008 0.0216 0.0214
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1861
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0062 0.0143 0.0141
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0052 0.0103 0.0726
Trichomonas vaginalis heat shock protein, putative 0.0087 0.0246 0.0471
Loa Loa (eye worm) hypothetical protein 0.0028 0.0007 0.0008
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0098 0.0184
Brugia malayi Immunoglobulin I-set domain containing protein 0.0029 0.0009 0.0008
Trypanosoma cruzi Heat shock protein 83, putative 0.0093 0.027 0.0876
Echinococcus granulosus chromobox protein 1 0.0069 0.0172 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0052 0.0103 0.0193
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0287 0.1063 0.1061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0051 0.0098 0.0184
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0066 0.0159 0.0508
Echinococcus granulosus cathepsin L 0.0052 0.0103 0.0101
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.032 0.1043
Brugia malayi cathepsin Z-like cysteine proteinase 0.0052 0.0103 0.0112
Brugia malayi Latrophilin receptor protein 2 0.008 0.0216 0.0238
Brugia malayi Cathepsin L-like cysteine proteinase 0.006 0.0136 0.0148
Trichomonas vaginalis bromodomain-containing protein, putative 0.0057 0.0124 0.0233
Schistosoma mansoni cathepsin S (C01 family) 0.0052 0.0103 0.0101
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0172 0.0328
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0051 0.0098 0.0184
Giardia lamblia Cathepsin L-like protease 0.0052 0.0103 0.0843
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0186 0.0184
Echinococcus granulosus fetal alzheimer antigen falz 0.0145 0.0482 0.048
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0052 0.0095
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0082 0.008
Entamoeba histolytica cysteine protease, putative 0.0105 0.032 0.3356
Echinococcus multilocularis raf serine:threonine protein kinase 0.0036 0.004 0.0038
Brugia malayi Bromodomain containing protein 0.0232 0.084 0.093
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.002 0.0131
Entamoeba histolytica cysteine protease, putative 0.0052 0.0103 0.0925
Giardia lamblia Heat shock protein HSP 90-alpha 0.0079 0.0215 0.199
Brugia malayi Cathepsin L-like precursor 0.0113 0.0353 0.039
Loa Loa (eye worm) hypothetical protein 0.005 0.0095 0.0106
Echinococcus multilocularis dnaJ subfamily B 0.2475 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Onchocerca volvulus 0.003 0.0015 0.0034
Brugia malayi Cathepsin L-like precursor 0.0113 0.0353 0.039
Plasmodium vivax unspecified product 0.0052 0.0103 0.0726
Loa Loa (eye worm) heat shock protein 90 0.0093 0.027 0.0299
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Loa Loa (eye worm) hypothetical protein 0.003 0.0015 0.0016
Schistosoma mansoni cpg binding protein 0.0174 0.0601 0.0599
Schistosoma mansoni hypothetical protein 0.008 0.0216 0.0214
Toxoplasma gondii cathepsin B 0.0272 0.1001 0.7535
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0041 0.0115
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0082 0.0761
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Brugia malayi jmjC domain containing protein 0.0127 0.0411 0.0454
Echinococcus granulosus cathepsin L cysteine proteinase 0.0113 0.0353 0.0351
Giardia lamblia Cysteine protease 0.0052 0.0103 0.0843
Echinococcus multilocularis geminin 0.1693 0.6808 0.6807
Loa Loa (eye worm) hypothetical protein 0.0035 0.0035 0.0038
Schistosoma mansoni endoplasmin 0.0093 0.027 0.0268
Brugia malayi TAR-binding protein 0.0063 0.0151 0.0165
Loa Loa (eye worm) hypothetical protein 0.015 0.0503 0.0558
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0037 0.0035
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0632 0.063
Trichomonas vaginalis glucosylceramidase, putative 0.0849 0.3359 0.6487
Schistosoma mansoni zinc finger protein 0.013 0.0424 0.0422
Entamoeba histolytica hypothetical protein 0.0072 0.0186 0.1861
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0113 0.0353 0.0677
Schistosoma mansoni methyl-cpg binding protein mbd 0.0102 0.0307 0.0305
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0763 0.3008 0.3006
Trichomonas vaginalis heat shock protein, putative 0.0079 0.0215 0.041
Echinococcus granulosus cysteine protease 0.0105 0.032 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0043 0.0067 0.0065
Echinococcus multilocularis chromobox protein 1 0.0069 0.0172 0.017
Echinococcus multilocularis heat shock protein 90 0.0079 0.0215 0.0213
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0066 0.0159 0.0494
Leishmania major trypanothione reductase 0.0189 0.0664 0.6614
Echinococcus granulosus thioredoxin glutathione reductase 0.0189 0.0664 0.0663
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.016 0.0546 0.5427
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0279 0.1033 0.1146
Loa Loa (eye worm) PHD-finger family protein 0.0088 0.0249 0.0276
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0049 0.0124
Echinococcus granulosus defective proboscis extension response 0.0029 0.0009 0.0007
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Onchocerca volvulus 0.005 0.0094 0.0242
Trichomonas vaginalis glucosylceramidase, putative 0.1294 0.5176 1
Plasmodium vivax heat shock protein, putative 0.0351 0.1325 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0027 0.002
Onchocerca volvulus Glucosylceramidase homolog 0.0849 0.3359 0.8861
Brugia malayi Fibronectin type III domain containing protein 0.0029 0.0009 0.0008
Leishmania major heat shock protein 83-1 0.0093 0.027 0.2644
Toxoplasma gondii PHD-finger domain-containing protein 0.0088 0.0249 0.1836
Loa Loa (eye worm) hypothetical protein 0.0094 0.0275 0.0305
Echinococcus multilocularis JmjC domain containing protein 4 0.0028 0.0007 0.0005
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0215 0.0768 0.0766
Schistosoma mansoni hypothetical protein 0.1693 0.6808 0.6807
Entamoeba histolytica hypothetical protein 0.0052 0.0103 0.0925

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference
Potency (functional) 6.3096 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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