Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0037 | 0.0283 | 0.0447 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.015 | 0.1724 | 0.8851 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.015 | 0.1724 | 0.2641 |
Echinococcus granulosus | GPCR family 2 | 0.0065 | 0.0639 | 0.0963 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0096 | 0.0152 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0639 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0043 | 0.0364 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0272 | 0.0257 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0042 | 0.0344 | 0.1704 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0043 | 0.0364 | 1 |
Onchocerca volvulus | 0.0036 | 0.0272 | 0.0513 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0042 | 0.0344 | 0.0329 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0066 | 0.0078 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0272 | 0.0337 |
Brugia malayi | conserved hypotetical protein | 0.002 | 0.0066 | 0.0105 |
Schistosoma mansoni | nuclear receptor | 0.002 | 0.0066 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0272 | 0.0431 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0042 | 0.0344 | 0.0329 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.0061 | 0.0236 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0513 | 0.632 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0426 | 0.2128 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0066 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0272 | 0.0431 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.002 | 0.0066 | 0.0051 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.002 | 0.0066 | 0.0051 |
Echinococcus granulosus | geminin | 0.0168 | 0.1945 | 0.2983 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0513 | 0.632 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0359 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0014 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0158 | 0.025 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1945 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0127 | 0.1422 | 0.2251 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0755 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0047 | 0.0414 | 0.0564 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0158 | 0.0143 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0138 | 0.4782 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0061 | 0.007 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0074 | 0.0755 | 0.3833 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.2438 | 0.3858 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.002 | 0.0066 | 0.0261 |
Schistosoma mansoni | nuclear receptor | 0.002 | 0.0066 | 0.0261 |
Brugia malayi | nuclear receptor NHR-88 | 0.0042 | 0.0344 | 0.0545 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0042 | 0.0344 | 0.1704 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.002 | 0.0066 | 0.0105 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0337 | 0.4084 | 0.6427 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0042 | 0.0344 | 0.0329 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0272 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0355 | 0.4314 | 0.6795 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0061 | 0.1775 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0158 | 0.022 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0022 | 0.0096 | 0.0416 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.002 | 0.0066 | 0.0051 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0066 | 0.0105 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0272 | 0.0948 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0061 | 0.1775 |
Brugia malayi | follicle stimulating hormone receptor | 0.0253 | 0.3027 | 0.4789 |
Onchocerca volvulus | 0.0027 | 0.0158 | 0.0229 | |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0061 | 0.0046 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0017 | 0.003 | 0.0558 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0337 | 0.4084 | 0.6427 |
Echinococcus granulosus | lamin | 0.0027 | 0.0158 | 0.022 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0639 | 0.0624 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0061 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0042 | 0.0344 | 0.0693 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0272 | 0.0431 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0272 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0127 | 0.1422 | 0.2251 |
Loa Loa (eye worm) | cytochrome P450 | 0.0016 | 0.0016 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1945 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0272 | 0.0431 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0526 | 0.6484 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.015 | 0.1724 | 0.8851 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0065 | 0.0639 | 0.1011 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0272 | 0.0948 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0022 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Schistosoma mansoni | coup transcription factor | 0.0042 | 0.0344 | 0.1704 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0226 | 0.2687 | 0.2675 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.003 | 0.0558 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0158 | 0.0143 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0344 | 0.0508 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0158 | 0.025 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.016 | 0.1846 | 0.1833 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0344 | 0.0545 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Loa Loa (eye worm) | DR-78 | 0.002 | 0.0066 | 0.0105 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0272 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0205 | 0.2413 | 0.3818 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0042 | 0.0344 | 0.0693 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0061 | 0.1775 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0158 | 0.0143 |
Brugia malayi | Cytochrome P450 family protein | 0.0016 | 0.0016 | 0.0025 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0042 | 0.0344 | 0.1704 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0025 | 0.0138 | 0.0219 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0344 | 0.0329 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.015 | 0.1724 | 0.2727 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0272 | 0.0396 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0158 | 0.022 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0017 | 0.003 | 0.0053 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0272 | 0.0431 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.002 | 0.0066 | 0.0105 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0639 | 0.3229 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0074 | 0.0755 | 0.0741 |
Brugia malayi | nuclear receptor RXR | 0.002 | 0.0066 | 0.0105 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0061 | 0.0236 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.002 | 0.0066 | 0.0078 |
Onchocerca volvulus | 0.0027 | 0.0158 | 0.0229 | |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0047 | 0.0414 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0048 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.015 | 0.1724 | 0.8851 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0042 | 0.0344 | 0.1704 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.0755 | 0.3833 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0138 | 0.4782 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.002 | 0.0066 | 0.0078 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0205 | 0.2413 | 0.3818 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0042 | 0.0344 | 0.1704 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0337 | 0.4084 | 0.6427 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0066 | 0.0105 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.015 | 0.1724 | 0.1711 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.002 | 0.0066 | 0.0051 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0042 | 0.0344 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Onchocerca volvulus | 0.0036 | 0.0272 | 0.0513 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0513 | 0.632 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0272 | 0.1329 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0042 | 0.0344 | 0.1704 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0205 | 0.2413 | 0.3818 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0513 | 0.632 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0337 | 0.4084 | 0.6427 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0272 | 0.0948 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.0061 | 0.1775 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0066 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0272 | 0.0431 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0272 | 0.0431 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0236 | 0.2802 | 0.4308 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0096 | 0.0416 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0022 | 0.0096 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0042 | 0.0344 | 0.1704 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.002 | 0.0066 | 0.0105 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0344 | 0.0545 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.0061 | 0.1775 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.015 | 0.1724 | 0.2727 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0272 | 0.1329 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0065 | 0.0639 | 0.1011 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0061 | 0.1775 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0025 | 0.0138 | 0.4782 |
Brugia malayi | hypothetical protein | 0.0252 | 0.3011 | 0.4764 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0272 | 0.6436 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.0061 | 0.0046 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0061 | 0.0097 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0042 | 0.0344 | 0.0508 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0158 | 0.025 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0043 | 0.0364 | 0.4367 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0065 | 0.0639 | 0.1011 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0061 | 0.0097 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0096 | 0.0152 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0272 | 1 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0359 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0138 | 0.0219 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0042 | 0.0344 | 0.0693 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2413 | 0.3818 |
Onchocerca volvulus | 0.0036 | 0.0272 | 0.0513 | |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0226 | 0.2687 | 0.4251 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.002 | 0.0066 | 0.0078 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0047 | 0.0414 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0096 | 0.0152 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.002 | 0.0066 | 0.0078 |
Schistosoma mansoni | nuclear hormone receptor | 0.0042 | 0.0344 | 0.1704 |
Brugia malayi | steroid hormone receptor | 0.0042 | 0.0344 | 0.0545 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.1592 | 0.8167 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.0061 | 0.0236 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0272 | 0.0337 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0639 | 0.3229 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0096 | 0.0152 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0236 | 0.2802 | 0.2791 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0344 | 0.0508 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.003 | 0.0558 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0061 | 0.0097 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.0061 | 0.007 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.016 | 0.1846 | 0.292 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.002 | 0.0066 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0639 | 0.0963 |
Brugia malayi | cytochrome P450 | 0.0016 | 0.0016 | 0.0025 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0158 | 0.025 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0526 | 0.6484 | 0.6478 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0272 | 0.0948 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0639 | 0.3229 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0022 | 0.0096 | 0.0152 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0127 | 0.1422 | 0.2251 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0204 | 0.2409 | 0.3811 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0014 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0022 | 0.0096 | 0.0124 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0047 | 0.0414 | 0.0616 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0272 | 0.0948 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.015 | 0.1724 | 0.1711 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0513 | 0.632 | 1 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0755 | 0.1195 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0272 | 0.0337 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0138 | 0.0219 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.0061 | 0.1775 |
Echinococcus multilocularis | GPCR, family 2 | 0.0065 | 0.0639 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0074 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0272 | 0.0948 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0156 | 0.1789 | 0.2741 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0272 | 0.0948 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0344 | 0.0545 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1945 | 0.1933 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0096 | 0.0152 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.0061 | 0.0097 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0344 | 0.0545 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0061 | 0.1775 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Onchocerca volvulus | Huntingtin homolog | 0.0252 | 0.3011 | 0.7328 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0344 | 0.0545 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0272 | 0.0948 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0066 | 0.0051 |
Onchocerca volvulus | 0.0048 | 0.0426 | 0.0897 | |
Leishmania major | cytochrome p450-like protein | 0.0025 | 0.0138 | 0.4782 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.003 | 0.0558 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.003 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0042 | 0.0344 | 0.0329 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0047 | 0.0414 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0337 | 0.4084 | 0.6427 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0272 | 0.0431 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0272 | 0.0948 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | acetyltransferase | 0.016 | 0.1846 | 0.292 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.015 | 0.1724 | 0.2641 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.002 | 0.0066 | 0.0051 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0513 | 0.632 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0337 | 0.4084 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.003 | 0.0558 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0526 | 0.6484 | 0.6478 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0096 | 0.0152 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0272 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0344 | 0.0545 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0061 | 0.0168 |
Trypanosoma brucei | cytochrome P450, putative | 0.0025 | 0.0138 | 0.4782 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0138 | 0.0219 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.0061 | 0.007 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0337 | 0.4084 | 0.6427 |
Brugia malayi | nuclear receptor NHR-67 | 0.002 | 0.0066 | 0.0105 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0344 | 0.0329 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0272 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0042 | 0.0344 | 0.0545 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.002 | 0.0066 | 0.0261 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0138 | 0.0219 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0066 | 0.0105 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0344 | 0.0329 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0272 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0152 | 0.024 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0066 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0236 | 0.2802 | 0.4434 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0344 | 0.0545 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0272 | 0.6303 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0337 | 0.4084 | 0.6427 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.002 | 0.0066 | 0.0078 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0344 | 0.0329 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0755 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1592 | 0.2519 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.002 | 0.0066 | 0.0261 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0096 | 0.0152 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0344 | 0.0508 |
Brugia malayi | ecdysteroid receptor | 0.0042 | 0.0344 | 0.0545 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0272 | 0.0337 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0229 | 0.2721 | 1 |
Brugia malayi | tailless protein | 0.002 | 0.0066 | 0.0105 |
Schistosoma mansoni | lamin | 0.0027 | 0.0158 | 0.0737 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0066 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 0.3011 | 0.4764 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0096 | 0.0152 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0272 | 1 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0272 | 0.0431 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0426 | 0.2128 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | Cytochrome P450 family protein | 0.0037 | 0.0283 | 0.0447 |
Echinococcus granulosus | neuropeptide s receptor | 0.0526 | 0.6484 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0061 | 0.1775 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.003 | 0.0014 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0344 | 0.1704 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0074 | 0.0755 | 0.1143 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0272 | 0.0337 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0272 | 0.0431 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0272 | 0.0337 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.002 | 0.0066 | 0.0105 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0272 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0344 | 0.0545 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0639 | 0.3229 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0639 | 0.0963 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.014 | 0.1592 | 0.2519 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.002 | 0.0066 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0042 | 0.0344 | 0.0508 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0344 | 0.1704 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0344 | 0.0545 |
Loa Loa (eye worm) | hypothetical protein | 0.0252 | 0.3011 | 0.4764 |
Brugia malayi | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Schistosoma mansoni | lamin | 0.0027 | 0.0158 | 0.0737 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0344 | 0.0508 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0272 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0042 | 0.0344 | 0.0508 |
Brugia malayi | hypothetical protein | 0.0236 | 0.2802 | 0.4434 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0226 | 0.2687 | 0.413 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0061 | 0.1775 |
Brugia malayi | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.0061 | 0.1775 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0639 | 0.0624 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0096 | 0.0152 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0042 | 0.0344 | 0.0545 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0042 | 0.0344 | 0.1704 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0061 | 0.0168 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0344 | 0.0545 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0426 | 0.0675 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0047 | 0.0414 | 0.0564 |
Brugia malayi | ecdysone receptor | 0.002 | 0.0066 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0272 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0355 | 0.4314 | 0.6795 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0066 | 0.0105 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0272 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.016 | 0.1846 | 0.9483 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0272 | 0.0431 |
Onchocerca volvulus | 0.0042 | 0.0344 | 0.0693 | |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0513 | 0.632 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0158 | 0.0737 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0755 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0158 | 0.025 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0253 | 0.3027 | 0.4789 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0042 | 0.0344 | 0.1704 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0513 | 0.632 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0252 | 0.3011 | 0.7328 |
Entamoeba histolytica | hypothetical protein | 0.0074 | 0.0755 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0272 | 0.0431 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0344 | 0.0545 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.