Detailed information for compound 1499934
Basic information
Technical information
Network
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Synonyms
No synonyms found for this compound
Targets
Known targets for this compound
No curated genes were found associated with this compound
Predicted pathogen targets for this compound
By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model
Ranking Plot
Putative Targets List
| Species | Potential target | Raw | Global | Species |
|---|---|---|---|---|
| Echinococcus granulosus | serotonin receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0067 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | dro:myosuppressin receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | g protein coupled receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | g protein coupled receptor | 0.0067 | 1 | 1 |
| Brugia malayi | GnHR receptor homolog | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | fmrfamide receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | neuropeptide F-like receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | fmrfamide receptor | 0.0067 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Trypanosoma brucei | DNA polymerase eta, putative | 0.0043 | 0.4975 | 1 |
| Echinococcus granulosus | orexin receptor type 2 | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Brugia malayi | Dopamine receptor protein 1 | 0.0067 | 1 | 1 |
| Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.8494 | 1 |
| Brugia malayi | G-protein coupled receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | neuropeptide receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0067 | 1 | 1 |
| Brugia malayi | neuropeptide F receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptides capa receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | dna polymerase eta | 0.0043 | 0.4975 | 0.4975 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Giardia lamblia | DINP protein human, muc B family | 0.0018 | 0 | 0.5 |
| Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptide Y receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | serotonin receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0067 | 1 | 1 |
| Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0018 | 0 | 0.5 |
| Echinococcus multilocularis | g-protein coupled receptor | 0.0067 | 1 | 1 |
| Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0067 | 1 | 0.5 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0067 | 1 | 1 |
| Brugia malayi | putative neuropeptide receptor | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Brugia malayi | G-protein coupled receptor | 0.0067 | 1 | 1 |
| Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0067 | 1 | 1 |
| Brugia malayi | ORL1-like opioid receptor | 0.0067 | 1 | 1 |
| Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0067 | 1 | 1 |
| Brugia malayi | Melatonin receptor type 1A | 0.0067 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | fmrfamide receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0067 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | opsin-like receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide Y receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | tm gpcr rhodopsin | 0.0067 | 1 | 1 |
| Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0067 | 1 | 1 |
| Schistosoma mansoni | myosin xvIII | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0067 | 1 | 1 |
| Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0067 | 1 | 1 |
| Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0067 | 1 | 1 |
| Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.8494 | 1 |
| Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0067 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | allatostatin A receptor | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.8494 | 1 |
| Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0067 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | sex peptide receptor | 0.0067 | 1 | 1 |
| Brugia malayi | Serotonin receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide Y receptor | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0067 | 1 | 1 |
| Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0067 | 1 | 1 |
| Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | opsin-like receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus granulosus | biogenic amine 5HT receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Schistosoma mansoni | neuropeptide receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | neuropeptide F receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptide receptor | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.8494 | 0.8494 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptide receptor A26 | 0.0067 | 1 | 1 |
| Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.8494 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.8494 | 1 |
| Loa Loa (eye worm) | TYRA-2 protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide s receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | allatostatin A receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptide s receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.8494 | 0.8494 |
| Brugia malayi | AKH receptor | 0.0067 | 1 | 1 |
| Brugia malayi | ImpB/MucB/SamB family protein | 0.0043 | 0.4975 | 0.4975 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | sex peptide receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | orexin receptor type 2 | 0.0067 | 1 | 1 |
| Brugia malayi | G protein-coupled receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Schistosoma mansoni | neuropeptide F-like receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0067 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | dna polymerase eta | 0.0043 | 0.4975 | 0.4975 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | 7tm_1 domain containing protein | 0.0067 | 1 | 1 |
| Trypanosoma cruzi | DNA polymerase eta, putative | 0.003 | 0.2376 | 0.4775 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Brugia malayi | putative neuropeptide receptor NPR1 | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4975 | 0.4975 |
| Echinococcus granulosus | G protein coupled receptor 139 | 0.0067 | 1 | 1 |
| Brugia malayi | follicle stimulating hormone receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | neuropeptide receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptides capa receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptides capa receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0067 | 1 | 1 |
| Schistosoma mansoni | opsin-like receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | neuropeptide F receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | melatonin receptor type 1A | 0.0067 | 1 | 1 |
| Echinococcus granulosus | g protein coupled receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0067 | 1 | 1 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0067 | 1 | 0.5 |
| Brugia malayi | sulfakinin receptor protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.8494 | 1 |
| Echinococcus multilocularis | g protein coupled receptor | 0.0067 | 1 | 1 |
| Brugia malayi | Serotonin receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Schistosoma mansoni | neuropeptide f receptor 76f | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptides capa receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptide Y receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Trichomonas vaginalis | DNA polymerase eta, putative | 0.0018 | 0 | 0.5 |
| Brugia malayi | RE15519p | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0067 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0067 | 1 | 1 |
| Brugia malayi | neuropeptide F receptor | 0.0067 | 1 | 1 |
| Brugia malayi | larval opioid receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | adenoreceptor | 0.0067 | 1 | 1 |
| Trypanosoma cruzi | DNA polymerase eta, putative | 0.0043 | 0.4975 | 1 |
| Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.8494 | 0.8494 |
| Brugia malayi | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | histamine h1 receptor | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0018 | 0 | 0.5 |
| Echinococcus multilocularis | somatostatin receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | tm gpcr rhodopsin | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | serotonin receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | biogenic amine 5HT receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | growth hormone secretagogue receptor | 0.0067 | 1 | 1 |
| Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | G protein coupled receptor 139 | 0.0067 | 1 | 1 |
| Leishmania major | DNA polymerase eta, putative | 0.003 | 0.2376 | 0.2797 |
| Leishmania major | DNA polymerase eta, putative | 0.0043 | 0.4975 | 0.5857 |
| Echinococcus granulosus | hypothetical protein | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | G-protein coupled receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | somatostatin receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Echinococcus granulosus | g-protein coupled receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0067 | 1 | 1 |
| Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0067 | 1 | 1 |
| Brugia malayi | Dopamine receptor protein 2 | 0.0067 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0067 | 1 | 1 |
| Schistosoma mansoni | biogenic amine receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Schistosoma mansoni | DNA polymerase eta | 0.0043 | 0.4975 | 0.4975 |
| Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.8494 | 0.8494 |
| Schistosoma mansoni | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | G-protein coupled receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | amine GPCR | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | neuropeptide receptor A26 | 0.0067 | 1 | 1 |
| Echinococcus granulosus | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | g protein coupled receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0067 | 1 | 1 |
| Schistosoma mansoni | neuropeptide receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Echinococcus granulosus | dro:myosuppressin receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Onchocerca volvulus | 0.0067 | 1 | 0.5 | |
| Echinococcus granulosus | neuropeptide receptor | 0.0067 | 1 | 1 |
| Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0067 | 1 | 1 |
| Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0067 | 1 | 1 |
| Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0067 | 1 | 1 |
| Brugia malayi | Dopamine receptor | 0.0067 | 1 | 1 |
| Echinococcus granulosus | tm gpcr rhodopsin | 0.0067 | 1 | 1 |
| Echinococcus granulosus | g protein coupled receptor | 0.0067 | 1 | 1 |
Activities
| Activity type | Activity value | Assay description | Source | Reference |
|---|---|---|---|---|
| IC50 (binding) | = 102 uM | Inhibition of His-tagged-truncated human PDK1 preincubated with substrate biotinylated-AKT3 for 30 mins measured after 3 hrs by Scintillation proximity assay | ChEMBL. | 24900229 |
Phenotypes
Whole-cell/tissue/organism interactions
We have no records of whole-cell/tissue assays done with this compound
What does this mean?
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Annotated phenotypes:
We have no manually annotated phenotypes for this drug.
What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by
drugs, or by genetic manipulation of cells (e.g. gene knockouts or
knockdowns) is manually curated from the literature. These
descriptions help to describe the potential of the target for drug
development. If no information is available for this gene or if the
information is incomplete, this may mean that i) the papers
containing this information either appeared after the curation
effort for this organism was carried out or they were inadvertently
missed by curators; or that ii) the curation effort for this
organism has not yet started.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.
External resources for this compound
- ChEMBL: CHEMBL1688209
Bibliographic References
1 literature reference was collected for this gene.
If you have references for this compound, please enter them in a user comment (below) or Contact us.