Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | Vacuolar proton pyrophosphatase 1, putative | 0.0694 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.0329 | 0.3815 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.0329 | 0.3815 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0329 | 0.3815 | 0.5 |
Echinococcus multilocularis | hexokinase type 2 | 0.0329 | 0.3815 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0329 | 0.3815 | 1 |
Onchocerca volvulus | 0.0329 | 0.3815 | 1 | |
Echinococcus granulosus | hexokinase type 2 | 0.0329 | 0.3815 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.0329 | 0.3815 | 0.5 |
Echinococcus granulosus | hexokinase | 0.0329 | 0.3815 | 0.5 |
Plasmodium vivax | vacuolar-type H+ pumping pyrophosphatase, putative | 0.0694 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.2037 | 0.5339 |
Trypanosoma brucei | Pyrophosphate-energized vacuolar membrane proton pump 2, putative | 0.0694 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.0329 | 0.3815 | 1 |
Brugia malayi | hexokinase | 0.0329 | 0.3815 | 1 |
Echinococcus granulosus | hexokinase | 0.0329 | 0.3815 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.0329 | 0.3815 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0207 | 0.1731 | 0.4537 |
Trypanosoma cruzi | vacuolar-type proton translocating pyrophosphatase 1 | 0.0694 | 1 | 1 |
Toxoplasma gondii | V-type H(+)-translocating pyrophosphatase VP1 | 0.0694 | 1 | 1 |
Onchocerca volvulus | 0.0329 | 0.3815 | 1 | |
Plasmodium falciparum | V-type H(+)-translocating pyrophosphatase, putative | 0.0694 | 1 | 1 |
Trypanosoma brucei | Pyrophosphate-energized vacuolar membrane proton pump 1 | 0.0694 | 1 | 1 |
Schistosoma mansoni | hexokinase | 0.0329 | 0.3815 | 0.5 |
Plasmodium vivax | V-type H(+)-translocating pyrophosphatase, putative | 0.0694 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.0207 | 0.1731 | 0.4537 |
Loa Loa (eye worm) | hexokinase type II | 0.0329 | 0.3815 | 1 |
Echinococcus multilocularis | hexokinase | 0.0329 | 0.3815 | 0.5 |
Plasmodium falciparum | V-type K+-independent H+-translocating inorganic pyrophosphatase | 0.0694 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0329 | 0.3815 | 1 |
Onchocerca volvulus | 0.0329 | 0.3815 | 1 | |
Entamoeba histolytica | hexokinase 2 | 0.0329 | 0.3815 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.