Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | nmda type glutamate receptor | 0.0084 | 0.0172 | 0.0172 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0364 | 0.6653 | 0.5 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0364 | 0.6653 | 0.5 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0091 | 0.0336 | 0.0336 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0509 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0084 | 0.0172 | 0.0172 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0364 | 0.6653 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0509 | 1 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0509 | 1 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0123 | 0.1079 | 0.0734 |
Schistosoma mansoni | P2X receptor subunit | 0.0215 | 0.3199 | 0.2936 |
Schistosoma mansoni | P2X receptor subunit | 0.0509 | 1 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0509 | 1 | 1 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0364 | 0.6653 | 0.5 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0093 | 0.0372 | 0.0372 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0364 | 0.6653 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0364 | 0.6653 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0215 | 0.3199 | 0.2936 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0093 | 0.0372 | 0.0372 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0509 | 1 | 1 |
Trichomonas vaginalis | hypothetical protein | 0.0364 | 0.6653 | 0.5 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0364 | 0.6653 | 0.5 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0364 | 0.6653 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0091 | 0.0336 | 0.0336 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0509 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.