Detailed information for compound 1502875

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 538.655 | Formula: C33H35FN4O2
  • H donors: 1 H acceptors: 3 LogP: 4.07 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#Cc1cccc(c1)[C@@]1(C[C@H]1CN1CCC(CC1)(NC(=O)C)c1ccccc1)C(=O)N(Cc1ccc(cc1)F)C
  • InChi: 1S/C33H35FN4O2/c1-24(39)36-32(27-8-4-3-5-9-27)15-17-38(18-16-32)23-29-20-33(29,28-10-6-7-26(19-28)21-35)31(40)37(2)22-25-11-13-30(34)14-12-25/h3-14,19,29H,15-18,20,22-23H2,1-2H3,(H,36,39)/t29-,33+/m0/s1
  • InChiKey: UFWKEBZNAVQKSE-RYCFQHDISA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens tachykinin receptor 3 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis tachykinin peptides receptor 99D Get druggable targets OG5_131969 All targets in OG5_131969
Echinococcus granulosus tachykinin peptides receptor 99D Get druggable targets OG5_131969 All targets in OG5_131969
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) serotonin transporter b 0.024 0.1595 0.1577
Schistosoma mansoni amine GPCR 0.0078 0.0466 0.0475
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0078 0.0466 0.0445
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1413 0.9795 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.003
Echinococcus granulosus expressed protein 0.037 0.2507 0.2544
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1413 0.9795 1
Brugia malayi nuclear hormone receptor 0.0175 0.1139 0.112
Loa Loa (eye worm) nuclear hormone receptor 0.0082 0.0494 0.0474
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1709 0.1744
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0034
Toxoplasma gondii hypothetical protein 0.0041 0.0203 0.0179
Onchocerca volvulus Neuropeptide F receptor homolog 0.0078 0.0466 0.1528
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0023 0.0021
Echinococcus granulosus transcription factor btf3 0.0035 0.0161 0.0144
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0278 0.1859 0.184
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0278 0.1859 0.184
Echinococcus granulosus tyrosine protein kinase Blk 0.004 0.0199 0.0183
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0246 0.0224
Brugia malayi hypothetical protein 0.002 0.0055 0.0034
Echinococcus multilocularis ecdysone induced protein 78C 0.0175 0.1139 0.1144
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0175 0.1139 0.1144
Schistosoma mansoni polycystin 1-related 0.002 0.0055 0.0056
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0078 0.0466 0.0456
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0041 0.0203 0.0182
Schistosoma mansoni glutathione synthetase 0.0026 0.0098 0.01
Brugia malayi Proteasome subunit alpha type 1 0.0278 0.1859 0.1841
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0047 0.025 0.0235
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0016 0.0032 0.0005
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.0736 0.0732
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0157 0.0159
Schistosoma mansoni rab6-interacting 0.002 0.0055 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0175 0.1139 0.112
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.003
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.0466 0.0475
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0065 0.0039
Echinococcus multilocularis phospholipase D 0.009 0.0548 0.054
Onchocerca volvulus 0.0078 0.0466 0.1528
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Leishmania major proteasome alpha 1 subunit, putative 0.0278 0.1859 0.184
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0078 0.0466 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0104 0.0105
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.004 0.0199 0.0183
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0078 0.0466 0.0456
Echinococcus granulosus proteasome subunit beta type 6 0.0278 0.1859 0.1881
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.023 0.0209
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.068 0.4673 0.4771
Onchocerca volvulus 0.024 0.1595 0.5707
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0278 0.1859 0.1881
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0055 0.0035
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0203 0.0187
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.0466 0.0445
Brugia malayi Sodium:neurotransmitter symporter family protein 0.024 0.1595 0.1577
Onchocerca volvulus 0.0021 0.0064 0.0043
Schistosoma mansoni nuclear receptor 0.0082 0.0494 0.0504
Loa Loa (eye worm) polyprenyl synthetase 0.0102 0.0629 0.0609
Treponema pallidum sodium- and chloride- dependent transporter 0.024 0.1595 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0064 0.0045
Schistosoma mansoni tyrosine kinase 0.0097 0.0594 0.0606
Echinococcus multilocularis geminin 0.0168 0.1093 0.1098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0086
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0066 0.0377 0.0356
Echinococcus granulosus GPCR family 2 0.0031 0.0136 0.0118
Echinococcus multilocularis serotonin receptor 0.0199 0.131 0.132
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.0606 0.0586
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0116 0.0093
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0278 0.1859 0.1898
Entamoeba histolytica proteasome subunit beta type 1, putative 0.1097 0.7591 0.7739
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0147
Mycobacterium ulcerans beta-lactamase 0.0036 0.0168 0.0105
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0168 0.0105
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Trypanosoma brucei proteasome alpha 7 subunit 0.0278 0.1859 0.184
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0047 0.025 0.0235
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0051 0.003
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0278 0.1859 0.184
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0179
Schistosoma mansoni tyrosine kinase 0.0161 0.1044 0.1066
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0175 0.1139 0.1163
Loa Loa (eye worm) TK protein kinase 0.004 0.0199 0.0178
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0078 0.0466 0.0475
Schistosoma mansoni hypothetical protein 0.0031 0.0136 0.0138
Trypanosoma cruzi Emopamil binding protein, putative 0.0406 0.2755 0.2739
Onchocerca volvulus 0.0078 0.0466 0.1528
Mycobacterium tuberculosis Conserved protein 0.0036 0.0168 0.0143
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0118 0.01
Schistosoma mansoni hypothetical protein 0.0302 0.2028 0.207
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.068 0.4673 0.4771
Loa Loa (eye worm) SRC-1 0.0047 0.025 0.0229
Brugia malayi proteasome subunit alpha type 6 0.0278 0.1859 0.1841
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0026 0.0098 0.0033
Schistosoma mansoni nuclear hormone receptor 0.0082 0.0494 0.0504
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0078 0.0466 0.0475
Brugia malayi G-protein coupled receptor 0.0078 0.0466 0.0445
Echinococcus multilocularis conserved hypothetical protein 0.0685 0.4704 0.4792
Echinococcus granulosus peptide allatostatin:somatostatin 0.0078 0.0466 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0086
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0064 0.0045
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.023 0.0208
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0278 0.1859 0.184
Brugia malayi Proteasome A-type and B-type family protein 0.0278 0.1859 0.1841
Plasmodium vivax importin-beta 2, putative 0.0028 0.0116 0.009
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.025 0.0235
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.01 0.0079
Loa Loa (eye worm) TK/INSR protein kinase 0.0097 0.0594 0.0574
Schistosoma mansoni nck2/grb4 0.0015 0.0021 0.0022
Schistosoma mansoni tyrosine kinase 0.0019 0.0048 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.015 0.0151
Schistosoma mansoni cytochrome P450 0.0021 0.0065 0.0067
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0203 0.0207
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0175 0.1139 0.1144
Schistosoma mansoni multidrug resistance protein 0.0021 0.0064 0.0066
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0051 0.003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0078 0.0466 0.0445
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0129 0.0112
Schistosoma mansoni lipoxygenase 0.0117 0.0736 0.0752
Echinococcus multilocularis 0.0092 0.0558 0.0551
Loa Loa (eye worm) hypothetical protein 0.002 0.0055 0.0034
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0051 0.003
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0064 0.0045
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0047 0.025 0.0235
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0175 0.1139 0.1163
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0065 0.0039
Loa Loa (eye worm) hypothetical protein 0.0199 0.131 0.1292
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus 7tm_1 domain containing protein 0.0078 0.0466 0.0456
Giardia lamblia Proteasome subunit beta type 1 0.1097 0.7591 0.7736
Schistosoma mansoni neuropeptide receptor 0.0078 0.0466 0.0475
Echinococcus granulosus tm gpcr rhodopsin 0.0078 0.0466 0.0456
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0278 0.1859 0.184
Loa Loa (eye worm) solute carrier family 6 member 4 0.024 0.1595 0.1577
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0126 0.0104
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0021 0.0064 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0175 0.1139 0.1144
Onchocerca volvulus Dual oxidase homolog 0.0026 0.01 0.0177
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.003
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0015 0.002 0.0019
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0278 0.1859 0.1881
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0126 0.0105
Mycobacterium ulcerans hypothetical protein 0.0036 0.0168 0.0105
Onchocerca volvulus 0.0078 0.0466 0.1528
Brugia malayi conserved hypotetical protein 0.0082 0.0494 0.0474
Schistosoma mansoni hypothetical protein 0.0078 0.0466 0.0475
Brugia malayi hypothetical protein 0.0019 0.0051 0.003
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Loa Loa (eye worm) PDE1B protein 0.0193 0.1264 0.1246
Loa Loa (eye worm) hypothetical protein 0.0098 0.0606 0.0586
Brugia malayi ABC transporter family protein 0.0021 0.0064 0.0043
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Onchocerca volvulus 0.0078 0.0466 0.1528
Loa Loa (eye worm) hypothetical protein 0.0066 0.0383 0.0362
Brugia malayi ORL1-like opioid receptor 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0028 0.0116 0.0095
Toxoplasma gondii ABC1 family protein 0.0036 0.0168 0.0143
Loa Loa (eye worm) hypothetical protein 0.024 0.1595 0.1577
Schistosoma mansoni ran 0.0021 0.0064 0.0065
Schistosoma mansoni peroxidasin 0.0026 0.01 0.0103
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.025 0.0235
Schistosoma mansoni ets-related 0.0218 0.1443 0.1473
Giardia lamblia GTOR 0.0045 0.023 0.0171
Echinococcus granulosus Nuclear hormone receptor HR96 0.0082 0.0494 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0065 0.0039
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Loa Loa (eye worm) TYRA-2 protein 0.0078 0.0466 0.0445
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0278 0.1859 0.184
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0197 0.0202
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Schistosoma mansoni hypothetical protein 0.0078 0.0466 0.0475
Echinococcus multilocularis neuropeptide receptor 0.0078 0.0466 0.0456
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0203 0.0207
Brugia malayi Animal haem peroxidase family protein 0.0026 0.01 0.0079
Toxoplasma gondii proteasome beta subunit 0.0278 0.1859 0.1875
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0078 0.0078
Onchocerca volvulus 0.0078 0.0466 0.1528
Entamoeba histolytica protein kinase, putative 0.0033 0.0147 0.0098
Loa Loa (eye worm) hypothetical protein 0.0032 0.014 0.0119
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0026 0.0098 0.0072
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0064 0.0014
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0278 0.1859 0.1841
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0055 0.0035
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1093 0.1115
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0278 0.1859 0.184
Echinococcus multilocularis growth factor receptor bound protein 2 0.0015 0.0021 0.0001
Leishmania major polyprenyl synthase, putative 0.0026 0.0098 0.0075
Trichomonas vaginalis abcb9, putative 0.0021 0.0064 0.0064
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0168 0.0171
Trypanosoma brucei proteasome beta 6 subunit 0.1097 0.7591 0.7586
Loa Loa (eye worm) DR-78 0.0082 0.0494 0.0474
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0278 0.1859 0.184
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0043
Leishmania major solanesyl-diphosphate synthase, putative 0.0026 0.0098 0.0075
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0175 0.1139 0.1163
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0051 0.0052
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0116 0.0098
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0028 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0023 0.0021
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0175 0.1139 0.1144
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0161 0.0138
Schistosoma mansoni nuclear hormone receptor 0.0175 0.1139 0.1163
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0051 0.0032
Leishmania major proteasome beta 2 subunit, putative 0.068 0.4673 0.466
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1093 0.1115
Brugia malayi photoreceptor-specific nuclear receptor 0.0175 0.1139 0.112
Echinococcus granulosus phospholipase D1 0.0102 0.0632 0.0625
Brugia malayi hypothetical protein 0.0121 0.0762 0.0743
Brugia malayi Serotonin receptor 0.0535 0.3656 0.3643
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0278 0.1859 0.1841
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0016 0.0032 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0051 0.005
Echinococcus granulosus Proteasome subunit alpha type 7 0.0278 0.1859 0.1881
Loa Loa (eye worm) hypothetical protein 0.1442 1 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0078 0.0466 0.0456
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0055 0.0028
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0036 0.0167 0.0143
Echinococcus multilocularis epidermal growth factor receptor 0.0161 0.1044 0.1048
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0021 0.0064 0.0042
Schistosoma mansoni hypothetical protein 0.0031 0.0136 0.0138
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0129 0.0104
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0104 0.0105
Trypanosoma cruzi Emopamil binding protein, putative 0.0406 0.2755 0.2739
Echinococcus granulosus peroxidasin 0.0026 0.01 0.0082
Brugia malayi Doublecortin family protein 0.002 0.0055 0.0034
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.042 0.04
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0278 0.1859 0.1875
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0278 0.1859 0.1898
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0168 0.017
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0278 0.1859 0.1881
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0102 0.0629 0.0616
Brugia malayi Animal haem peroxidase family protein 0.0026 0.01 0.0079
Schistosoma mansoni peroxidasin 0.0026 0.01 0.0103
Loa Loa (eye worm) neuropeptide F receptor 0.0078 0.0466 0.0445
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0175 0.1139 0.1144
Entamoeba histolytica hypothetical protein 0.0035 0.0161 0.0112
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Schistosoma mansoni coup transcription factor 0.0175 0.1139 0.1163
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0016 0.0032 0.001
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0028 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0008
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0082 0.0494 0.0504
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Plasmodium vivax proteasome subunit beta type-3, putative 0.0278 0.1859 0.1875
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0078 0.0466 0.0445
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0026 0.0098 0.0079
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1413 0.9795 0.9794
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0278 0.1859 0.184
Brugia malayi hypothetical protein 0.0082 0.0494 0.0474
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0066 0.0377 0.0356
Loa Loa (eye worm) hypothetical protein 0.024 0.1595 0.1577
Echinococcus granulosus tachykinin peptides receptor 99D 0.0435 0.2963 0.301
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0278 0.1859 0.1881
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0023 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0065 0.0039
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0019 0.0048 0.0028
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0278 0.1859 0.1855
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0278 0.1859 0.1843
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0064 0.0045
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0065 0.0039
Echinococcus granulosus epidermal growth factor receptor 0.0298 0.2001 0.2027
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0051 0.0032
Loa Loa (eye worm) hypothetical protein 0.024 0.1595 0.1577
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0078 0.0466 0.0456
Brugia malayi SRC-1 0.0047 0.025 0.0229
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0278 0.1859 0.1875
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0051 0.0032
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0278 0.1859 0.1875
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0168 0.0105
Echinococcus multilocularis proteasome subunit alpha type 6 0.0278 0.1859 0.1881
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Brugia malayi Nuclear hormone receptor E75 0.0082 0.0494 0.0474
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.0466 0.0445
Brugia malayi Proteasome A-type and B-type family protein 0.0278 0.1859 0.1841
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.0466 0.0456
Echinococcus multilocularis serotonin receptor 0.0199 0.131 0.132
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.1366 0.1347
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0435 0.2963 0.301
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0064 0.0045
Trypanosoma brucei Emopamil binding protein, putative 0.0406 0.2755 0.2739
Brugia malayi Pre-SET motif family protein 0.003 0.0129 0.0108
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0028 0.0006
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0026 0.0098 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0175 0.1139 0.112
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0065 0.0039
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0102 0.0629 0.0641
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1093 0.1115
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0065 0.0043
Echinococcus multilocularis proteasome (prosome, macropain) 0.1413 0.9795 1
Brugia malayi proteasome subunit alpha type 3 0.0278 0.1859 0.1841
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0161 0.0136
Brugia malayi beta-lactamase 0.0036 0.0168 0.0147
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0086 0.0517 0.0479
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.012 0.0121
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0078 0.0466 0.0456
Brugia malayi Ets-domain containing protein 0.0072 0.042 0.04
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0064 0.0045
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0064 0.0064
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0203 0.0179
Echinococcus granulosus dnaJ subfamily B 0.0406 0.2755 0.2798
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0168 0.0171
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0065 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0161 0.0162
Loa Loa (eye worm) hypothetical protein 0.0061 0.0348 0.0327
Echinococcus multilocularis g-protein coupled receptor 0.0078 0.0466 0.0456
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.068 0.4673 0.477
Giardia lamblia 20S proteasome alpha subunit 2 0.0278 0.1859 0.1845
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0278 0.1859 0.184
Trypanosoma brucei cytochrome P450, putative 0.003 0.0126 0.0104
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1413 0.9795 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0348 0.0356
Plasmodium falciparum proteasome subunit beta type-4 0.0278 0.1859 0.1875
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0278 0.1859 0.1845
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0278 0.1859 0.1855
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0065 0.0043
Schistosoma mansoni tyrosine kinase 0.0157 0.1018 0.1039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0147
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0136 0.0115
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0065 0.0039
Brugia malayi Animal haem peroxidase family protein 0.0026 0.01 0.0079
Onchocerca volvulus 0.0065 0.0375 0.1194
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0041 0.0203 1
Onchocerca volvulus 0.0028 0.0117 0.0239
Schistosoma mansoni nuclear receptor nhr-48 0.0082 0.0494 0.0504
Brugia malayi hypothetical protein 0.0092 0.0563 0.0543
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0278 0.1859 0.1855
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0078 0.0466 0.1528
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.023 0.0183
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0388 0.0368
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0182
Echinococcus granulosus g protein coupled receptor 0.0078 0.0466 0.0456
Echinococcus multilocularis tyrosine protein kinase Fyn 0.004 0.0199 0.0183
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0501 0.0491
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0246 0.0224
Brugia malayi hypothetical protein 0.0041 0.0203 0.0182
Brugia malayi Cytochrome P450 family protein 0.003 0.0126 0.0105
Plasmodium falciparum proteasome subunit beta type-1, putative 0.1097 0.7591 0.7744
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0175 0.1139 0.1144
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0175 0.1139 0.1163
Onchocerca volvulus 0.0082 0.0494 0.1633
Brugia malayi orphan nuclear receptor NR2E1 0.0082 0.0494 0.0474
Schistosoma mansoni hypothetical protein 0.0078 0.0466 0.0475
Schistosoma mansoni neuropeptide receptor 0.0078 0.0466 0.0475
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0175 0.1139 0.112
Leishmania major proteasome beta 2 subunit, putative 0.0278 0.1859 0.184
Echinococcus granulosus proteasome subunit beta t family 0.0278 0.1859 0.1881
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0278 0.1859 0.1875
Plasmodium vivax proteasome subunit beta type-5, putative 0.1413 0.9795 1
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0019 0.0053 0.003
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0168 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0051 0.005
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0064 0.0064
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0021 0.0022
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0168 0.0146
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0098 0.0075
Schistosoma mansoni growth hormone secretagogue receptor 0.0078 0.0466 0.0475
Echinococcus granulosus insulin receptor 0.0097 0.0594 0.0587
Echinococcus granulosus proteasome prosome macropain subunit beta 0.1097 0.7591 0.7746
Onchocerca volvulus 0.0078 0.0466 0.1528
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.0629 0.0641
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0102 0.0629 0.0616
Loa Loa (eye worm) G-protein coupled receptor 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Schistosoma mansoni zinc finger protein 0.0082 0.0494 0.0504
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0489 0.3337 0.3323
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0466 0.0456
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0065 0.0039
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0168 0.0151
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.0167 0.0145
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0023 0.0023
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0064 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0129 0.0132
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0082 0.0494 0.1633
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Echinococcus multilocularis serotonin transporter 0.024 0.1595 0.1611
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0175 0.1139 0.112
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.0466 0.0456
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0021 0.0064 0.0038
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0278 0.1859 0.1898
Leishmania major hypothetical protein, conserved 0.0036 0.0168 0.0146
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.068 0.4673 0.477
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0055 0.0035
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Brugia malayi nuclear receptor NHR-67 0.0082 0.0494 0.0474
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.01 0.0079
Echinococcus granulosus Proteasome subunit alpha beta 0.0278 0.1859 0.1881
Brugia malayi Peroxidasin 0.0026 0.01 0.0079
Echinococcus multilocularis FTZ F1 alpha 0.0175 0.1139 0.1144
Schistosoma mansoni biogenic amine receptor 0.0078 0.0466 0.0475
Echinococcus granulosus proteasome subunit alpha type 6 0.0278 0.1859 0.1881
Brugia malayi Polyprenyl synthetase family protein 0.0026 0.0098 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1709 0.1744
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0051 0.0032
Echinococcus granulosus tyrosine kinase 0.004 0.0199 0.0183
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0278 0.1859 0.184
Schistosoma mansoni importin beta-1 0.0028 0.0116 0.0118
Giardia lamblia Proteasome subunit beta type 3 0.0278 0.1859 0.1845
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0377 0.0358
Loa Loa (eye worm) PAS-3 protein 0.0278 0.1859 0.1841
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0086
Onchocerca volvulus 0.0082 0.0494 0.1633
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.0791 0.0789
Loa Loa (eye worm) cytochrome P450 family protein 0.0059 0.033 0.0309
Loa Loa (eye worm) hypothetical protein 0.0092 0.0563 0.0543
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1093 0.1115
Brugia malayi Polyprenyl synthetase family protein 0.0102 0.0629 0.0609
Leishmania major farnesyl pyrophosphate synthase 0.0102 0.0629 0.0608
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0047 0.025 0.0235
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0078 0.0056
Trypanosoma brucei C-8 sterol isomerase, putative 0.1442 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Leishmania major cytochrome p450-like protein 0.003 0.0126 0.0104
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0065 0.0039
Schistosoma mansoni hypothetical protein 0.0168 0.1093 0.1116
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.023 0.0183
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1413 0.9795 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0086
Onchocerca volvulus 0.0036 0.0168 0.0426
Leishmania major proteasome beta 3 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Onchocerca volvulus Peroxidasin homolog 0.0026 0.01 0.0177
Onchocerca volvulus 0.0078 0.0466 0.1528
Echinococcus granulosus neuropeptide receptor 0.0078 0.0466 0.0456
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.068 0.4673 0.476
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0161 0.0112
Echinococcus granulosus sex peptide receptor 0.0078 0.0466 0.0456
Giardia lamblia Proteasome subunit beta type 2 0.068 0.4673 0.4736
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Schistosoma mansoni opsin-like receptor 0.0078 0.0466 0.0475
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.09 0.6209 0.6332
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0041 0.0203 0.0187
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0066 0.0043
Brugia malayi beta-lactamase family protein 0.0036 0.0168 0.0147
Schistosoma mansoni hypothetical protein 0.0078 0.0466 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0103 0.0103
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0028 0.0005
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0065 0.0043
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0064 0.0014
Loa Loa (eye worm) proteasome subunit beta type 1 0.1097 0.7591 0.7586
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0278 0.1859 0.1881
Echinococcus multilocularis expressed protein 0.037 0.2507 0.2544
Echinococcus granulosus thyroid hormone receptor alpha 0.0082 0.0494 0.0485
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0055 0.0028
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0051 0.0052
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.023 0.0208
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0065 0.0039
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0026 0.0098 0.0077
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0064 0.0045
Brugia malayi proteasome subunit alpha type 2 0.0278 0.1859 0.1841
Echinococcus multilocularis dro:myosuppressin receptor 0.0078 0.0466 0.0456
Echinococcus granulosus orexin receptor type 2 0.0078 0.0466 0.0456
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0161 0.0162
Onchocerca volvulus 0.0036 0.0168 0.0426
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0023 0.0002
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0466 0.0475
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0051 0.0052
Schistosoma mansoni hypothetical protein 0.0036 0.0168 0.0171
Echinococcus granulosus 7TM GPCR rhodopsin 0.0078 0.0466 0.0456
Echinococcus multilocularis tyrosine protein kinase Blk 0.004 0.0199 0.0183
Leishmania major proteasome alpha 7 subunit, putative 0.0278 0.1859 0.184
Brugia malayi bZIP transcription factor family protein 0.0083 0.0501 0.048
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.023 0.0214
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0175 0.1139 0.1144
Brugia malayi Cytochrome P450 family protein 0.0021 0.0065 0.0044
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0066 0.0377 0.0366
Plasmodium falciparum amino acid transporter, putative 0.0041 0.0203 0.0179
Brugia malayi Dopamine receptor protein 2 0.0078 0.0466 0.0445
Toxoplasma gondii proteasome subunit 0.0278 0.1859 0.1875
Echinococcus multilocularis snurportin 1 0.0302 0.2028 0.2054
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Brugia malayi proteasome subunit beta type 2 0.068 0.4673 0.4661
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0098 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0023 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0166 0.0168
Loa Loa (eye worm) hypothetical protein 0.0489 0.3337 0.3323
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0064 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.015 0.0151
Brugia malayi RE15519p 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0182
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0065 0.0039
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0168 0.0151
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0168 0.0151
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.042 0.0409
Entamoeba histolytica P-glycoprotein-1 0.0021 0.0064 0.0014
Trichomonas vaginalis taga, putative 0.0021 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase Abl 0.0019 0.0048 0.0028
Loa Loa (eye worm) proteasome subunit beta type 3 0.0278 0.1859 0.1841
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0175 0.1139 0.112
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0047 0.025 0.0235
Schistosoma mansoni smdr2 0.0021 0.0064 0.0066
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0064 0.0064
Echinococcus granulosus neuropeptide receptor 0.0078 0.0466 0.0456
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0026 0.0098 0.3828
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.023 0.0233
Onchocerca volvulus 0.0236 0.1565 0.5597
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1413 0.9795 0.9794
Loa Loa (eye worm) fli-1 protein 0.0218 0.1443 0.1425
Schistosoma mansoni cpg binding protein 0.003 0.0129 0.0131
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0278 0.1859 0.1845
Schistosoma mansoni jun-related protein 0.0068 0.0391 0.04
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0126 0.0105
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0041 0.0203 0.0187
Toxoplasma gondii heat shock protein hslv, putative 0.0278 0.1859 0.1875
Trichomonas vaginalis set domain proteins, putative 0.0236 0.1565 0.1597
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0026 0.0098 0.0072
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Toxoplasma gondii peptidase, T1 family protein 0.0278 0.1859 0.1875
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.042 0.0409
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1709 0.1744
Echinococcus granulosus biogenic amine 5HT receptor 0.0078 0.0466 0.0456
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0278 0.1859 0.1855
Trypanosoma brucei C-14 sterol reductase, putative 0.0047 0.0246 0.0224
Loa Loa (eye worm) hypothetical protein 0.0016 0.0032 0.0011
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0064 0.0041
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0051 0.005
Onchocerca volvulus Peroxidasin homolog 0.0026 0.01 0.0177
Echinococcus multilocularis orexin receptor type 2 0.0078 0.0466 0.0456
Brugia malayi G protein-coupled receptor 0.0078 0.0466 0.0445
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0028 0.0008
Loa Loa (eye worm) hypothetical protein 0.003 0.0129 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Brugia malayi Protein K4 0.0016 0.0032 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0065 0.0039
Echinococcus granulosus cpg binding protein 0.003 0.0129 0.0111
Loa Loa (eye worm) hypothetical protein 0.0092 0.0563 0.0543
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0126 0.0062
Trichomonas vaginalis ran, putative 0.0021 0.0064 0.0063
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0278 0.1859 0.1875
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0051 0.0032
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Schistosoma mansoni amine GPCR 0.0078 0.0466 0.0475
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0064 0.0044
Echinococcus multilocularis tyrosine protein kinase Srms 0.004 0.0199 0.0183
Schistosoma mansoni microtubule-associated protein tau 0.0685 0.4704 0.4803
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1157 0.1179
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0175 0.1139 0.1144
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0278 0.1859 0.184
Echinococcus multilocularis transcription factor btf3 0.0035 0.0161 0.0144
Echinococcus granulosus tyrosine protein kinase Src42A 0.0047 0.025 0.0235
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0175 0.1139 0.1144
Echinococcus granulosus g protein coupled receptor 0.0078 0.0466 0.0456
Schistosoma mansoni alpha-1 adrenergic receptor 0.0078 0.0466 0.0475
Loa Loa (eye worm) hypothetical protein 0.0457 0.3113 0.3098
Brugia malayi PXA domain containing protein 0.0023 0.0082 0.0061
Entamoeba histolytica hypothetical protein 0.0036 0.0168 0.012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0175 0.1139 0.112
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0064 0.0064
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0126 0.0104
Loa Loa (eye worm) hypothetical protein 0.0021 0.0063 0.0042
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0278 0.1859 0.1898
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.023 0.0209
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0078 0.0466 0.0475
Brugia malayi proteasome subunit beta type 1 0.1097 0.7591 0.7586
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0175 0.1139 0.112
Onchocerca volvulus 0.0078 0.0466 0.1528
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.015 0.0151
Loa Loa (eye worm) cytochrome P450 0.0021 0.0065 0.0044
Brugia malayi hypothetical protein 0.0065 0.0375 0.0355
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.068 0.4673 0.466
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus multilocularis 0.0021 0.0065 0.0046
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.0791 0.0789
Echinococcus granulosus allatostatin A receptor 0.0078 0.0466 0.0456
Echinococcus multilocularis sex peptide receptor 0.0078 0.0466 0.0456
Brugia malayi Animal haem peroxidase family protein 0.0026 0.01 0.0079
Echinococcus granulosus subfamily T1A non peptidase ue 0.0278 0.1859 0.1881
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0097 0.0594 0.0587
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0082 0.0494 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0023 0.0021
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Brugia malayi tailless protein 0.0082 0.0494 0.0474
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Echinococcus multilocularis ATP binding cassette sub family B 0.0021 0.0063 0.0044
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0203 0.0187
Onchocerca volvulus 0.0041 0.0203 0.0555
Echinococcus granulosus hypothetical protein 0.0763 0.5252 0.5352
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Loa Loa (eye worm) hypothetical protein 0.0019 0.0053 0.0032
Plasmodium vivax proteasome subunit beta type-4, putative 0.0278 0.1859 0.1875
Schistosoma mansoni tyrosine kinase 0.0019 0.0048 0.0049
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0278 0.1859 0.184
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0064 0.0045
Leishmania major proteasome alpha 3 subunit, putative 0.0278 0.1859 0.184
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0065 0.0039
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0065 0.0039
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0026 0.0098 0.0079
Echinococcus granulosus nuclear receptor nhr 48 0.0082 0.0494 0.0485
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Brugia malayi Nuclear hormone receptor-like 1 0.0092 0.0563 0.0543
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0278 0.1859 0.184
Onchocerca volvulus Peroxidase homolog 0.0026 0.01 0.0177
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.1097 0.7591 0.7586
Echinococcus granulosus proteasome subunit alpha type 2 0.0278 0.1859 0.1881
Toxoplasma gondii hypothetical protein 0.0041 0.0203 0.0179
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0028 0.0005
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0203 0.0207
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0302 0.2028 0.2011
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0175 0.1139 0.112
Brugia malayi Dopamine receptor 0.0078 0.0466 0.0445
Giardia lamblia 20S proteasome alpha subunit 5 0.0278 0.1859 0.1845
Plasmodium vivax proteasome subunit beta type-2, putative 0.068 0.4673 0.4756
Schistosoma mansoni tyrosine kinase 0.0047 0.025 0.0255
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0051 0.0032
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0064 0.0064
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Schistosoma mansoni hypothetical protein 0.0021 0.0065 0.0067
Onchocerca volvulus 0.0406 0.2755 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Loa Loa (eye worm) TK protein kinase 0.0033 0.0147 0.0126
Leishmania major proteasome beta 7 subunit, putative 0.0278 0.1859 0.184
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0082 0.0494 0.0485
Echinococcus granulosus proteasome prosome macropain subunit beta 0.068 0.4673 0.476
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0168 0.017
Toxoplasma gondii proteasome subunit alpha type, putative 0.0278 0.1859 0.1875
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0168 0.0143
Schistosoma mansoni tyrosine kinase 0.0157 0.1018 0.1039
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0278 0.1859 0.184
Brugia malayi Fli-1 protein 0.0218 0.1443 0.1425
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus g protein coupled receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) hypothetical protein 0.0092 0.0563 0.0543
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0203 0.0207
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0278 0.1859 0.184
Mycobacterium tuberculosis Conserved protein 0.0036 0.0168 0.0143
Echinococcus multilocularis GPCR, family 2 0.0031 0.0136 0.0118
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Brugia malayi steroid hormone receptor 0.0175 0.1139 0.112
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0278 0.1859 0.1881
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.1157 0.1179
Schistosoma mansoni adapter molecule crk 0.0015 0.0021 0.0022
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0406 0.2755 0.2739
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0175 0.1139 0.112
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0168 0.0143
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1413 0.9795 0.9794
Schistosoma mansoni phospholipase D 0.0102 0.0632 0.0645
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0028 0.0005
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0278 0.1859 0.184
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0278 0.1859 0.184
Loa Loa (eye worm) hypothetical protein 0.0086 0.0517 0.0497
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0278 0.1859 0.1875
Brugia malayi ecdysteroid receptor 0.0175 0.1139 0.112
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0051 0.003
Plasmodium falciparum importin beta, putative 0.0028 0.0116 0.009
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0078 0.0466 0.0456
Echinococcus granulosus RUN 0.002 0.0055 0.0035
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0168 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0051 0.005
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0051 0.003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0175 0.1139 0.112
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0278 0.1859 0.1841
Leishmania major cytochrome p450-like protein 0.0021 0.0065 0.0043
Leishmania major C-8 sterol isomerase-like protein 0.1442 1 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0051 0.0032
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0278 0.1859 0.1855
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0136 0.0118
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0157 0.0159
Trypanosoma brucei cardiolipin synthetase 0.0036 0.0167 0.0145
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0023 0.0021
Echinococcus granulosus jun protein 0.0083 0.0501 0.0491
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0168 0.017
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0203 0.0207
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0041 0.0203 0.0207
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0303 0.0282
Echinococcus multilocularis insulin receptor 0.0097 0.0594 0.0587
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0278 0.1859 0.1898
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0203 0.0187
Schistosoma mansoni hypothetical protein 0.0406 0.2755 0.2813
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0047 0.025 0.0235
Brugia malayi Cytochrome P450 family protein 0.003 0.0126 0.0105
Brugia malayi Animal haem peroxidase family protein 0.0026 0.01 0.0079
Onchocerca volvulus 0.0078 0.0466 0.1528
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0041 0.0203 0.0187
Schistosoma mansoni neuropeptide f receptor 76f 0.0078 0.0466 0.0475
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0051 0.0032
Brugia malayi Tachykinin-like peptides receptor 99D 0.0078 0.0466 0.0445
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0064 0.0045
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0064 0.0037
Loa Loa (eye worm) melatonin receptor type 1A 0.0078 0.0466 0.0445
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0064 0.0041
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0026 0.0098 0.0048
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Brugia malayi isocitrate dehydrogenase 0.0016 0.0028 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.003
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0082 0.0494 0.0474
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0147 0.0129
Brugia malayi nuclear receptor RXR 0.0092 0.0563 0.0543
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0021 0.0063 0.0044
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0064 0.0044
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0064 0.0064
Brugia malayi neuropeptide F receptor 0.0078 0.0466 0.0445
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0078 0.0466 0.0475
Echinococcus granulosus tm gpcr rhodopsin 0.0592 0.4055 0.4128
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0026 0.0098 0.0357
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0278 0.1859 1
Brugia malayi Melatonin receptor type 1A 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Entamoeba histolytica phospholipase D, putative 0.0102 0.0632 0.0596
Brugia malayi Proteasome subunit alpha type 7-1 0.0278 0.1859 0.1841
Leishmania major proteasome beta 5 subunit, putative 0.1413 0.9795 0.9794
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.018 0.1178 0.1184
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0278 0.1859 0.1855
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Schistosoma mansoni biogenic amine (5HT) receptor 0.0078 0.0466 0.0475
Schistosoma mansoni biogenic amine (5HT) receptor 0.0199 0.131 0.1338
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0092 0.0563 0.0555
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Entamoeba histolytica hypothetical protein 0.0036 0.0168 0.012
Brugia malayi nuclear hormone receptor family member nhr-6 0.0082 0.0494 0.0474
Schistosoma mansoni multidrug resistance protein 0.0021 0.0064 0.0066
Echinococcus multilocularis RUN 0.002 0.0055 0.0035
Echinococcus multilocularis fmrfamide receptor 0.0078 0.0466 0.0456
Brugia malayi Protein kinase domain containing protein 0.0097 0.0594 0.0574
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0278 0.1859 0.1896
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0078 0.0466 0.0445
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0278 0.1859 0.1881
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0278 0.1859 0.1841
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0051 0.005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0078 0.0078
Giardia lamblia 20S proteasome alpha subunit 3 0.0278 0.1859 0.1845
Plasmodium falciparum proteasome subunit beta type-2, putative 0.068 0.4673 0.4756
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus c src tyrosine kinase 0.0019 0.0048 0.0028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0136 0.0115
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0055 0.0035
Trypanosoma cruzi C-14 sterol reductase, putative 0.0047 0.0246 0.0224
Leishmania major basic transcription factor 3a, putative 0.0035 0.0161 0.0138
Schistosoma mansoni gabp alpha 0.0072 0.042 0.0429
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.023 0.0208
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0102 0.0629 0.0616
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0147
Giardia lamblia Farnesyl diphosphate synthase 0.0102 0.0629 0.0581
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0116 0.0093
Echinococcus granulosus fmrfamide receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0278 0.1859 0.1881
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0026 0.0098 0.0033
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.1097 0.7591 0.7746
Brugia malayi ecdysone receptor 0.0082 0.0494 0.0474
Echinococcus multilocularis epidermal growth factor receptor 0.0298 0.2001 0.2027
Brugia malayi beta-lactamase family protein 0.0036 0.0168 0.0147
Echinococcus granulosus G protein coupled receptor 139 0.0078 0.0466 0.0456
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1442 1 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0064 0.0037
Schistosoma mansoni neuropeptide receptor 0.0078 0.0466 0.0475
Onchocerca volvulus 0.0036 0.0168 0.0426
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.0629 0.058
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Schistosoma mansoni myosin xvIII 0.0078 0.0466 0.0475
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0278 0.1859 0.1896
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Schistosoma mansoni trans-prenyltransferase 0.0026 0.0098 0.01
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0173 0.0156
Loa Loa (eye worm) CYP4Cod1 0.003 0.0126 0.0105
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.01 0.0177
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Toxoplasma gondii proteasome subunit alpha1, putative 0.0278 0.1859 0.1875
Plasmodium falciparum multidrug resistance protein 1 0.0021 0.0064 0.0038
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Loa Loa (eye worm) multidrug resistance protein 3 0.0021 0.0064 0.0043
Echinococcus multilocularis G-protein coupled receptor, putative 0.0078 0.0466 0.0456
Brugia malayi GnHR receptor homolog 0.0078 0.0466 0.0445
Brugia malayi Phospholipase D. Active site motif family protein 0.0019 0.0053 0.0032
Trichomonas vaginalis esterase, putative 0.0036 0.0168 0.017
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0256 0.1709 0.1692
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0066 0.0377 0.0356
Onchocerca volvulus 0.0175 0.1139 0.4019
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0051 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0501 0.0491
Leishmania major cytochrome p450-like protein 0.0021 0.0065 0.0043
Trypanosoma brucei proteasome subunit beta type-2, putative 0.068 0.4673 0.466
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus snurportin 1 0.0302 0.2028 0.2054
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0065 0.0039
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0278 0.1859 0.1875
Schistosoma mansoni ran 0.0021 0.0064 0.0065
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trypanosoma brucei cardiolipin synthetase, putative 0.0036 0.0167 0.0145
Schistosoma mansoni transcription factor btf3 0.0035 0.0161 0.0164
Echinococcus granulosus serotonin transporter 0.024 0.1595 0.1611
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0078 0.0466 0.0456
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0129 0.0132
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0278 0.1859 0.1898
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0082 0.0494 0.0485
Echinococcus granulosus phospholipase D 0.009 0.0548 0.054
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.023 0.0208
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0175 0.1139 0.112
Schistosoma mansoni hypothetical protein 0.002 0.0055 0.0056
Loa Loa (eye worm) doublecortin family protein 0.002 0.0055 0.0034
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1093 0.1115
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Brugia malayi proteasome subunit alpha type 4 0.0278 0.1859 0.1841
Brugia malayi RNA, U transporter 1 0.008 0.048 0.046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0129 0.0132
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0026 0.0098 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1093 0.1115
Brugia malayi AKH receptor 0.0078 0.0466 0.0445
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0086
Echinococcus granulosus multidrug resistance protein 1 0.0021 0.0064 0.0045
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0161 0.0162
Schistosoma mansoni opsin-like receptor 0.0078 0.0466 0.0475
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0051 0.0032
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0102 0.0629 0.0608
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0102 0.0629 0.058
Schistosoma mansoni opsin-like receptor 0.0078 0.0466 0.0475
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Onchocerca volvulus 0.0078 0.0466 0.1528
Loa Loa (eye worm) hypothetical protein 0.0021 0.0064 0.0043
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0064 0.0014
Onchocerca volvulus 0.0078 0.0466 0.1528
Brugia malayi CXXC zinc finger family protein 0.0028 0.0117 0.0096
Echinococcus granulosus dro:myosuppressin receptor 0.0078 0.0466 0.0456
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0278 0.1859 0.1896
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0278 0.1859 0.1881
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0051 0.0032
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0168 0.0105
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0102 0.0629 0.0623
Entamoeba histolytica P-glyco protein 6, putative 0.0021 0.0064 0.0014
Brugia malayi hypothetical protein 0.0082 0.0494 0.0474
Leishmania major C-14 sterol reductase, putative 0.0047 0.0246 0.0224
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0278 0.1859 0.1855
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0168 0.017
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0026 0.0098 0.0075
Echinococcus granulosus neuropeptide receptor A26 0.0535 0.3656 0.372
Onchocerca volvulus 0.0041 0.0203 0.0555
Brugia malayi Phospholipase D. Active site motif family protein 0.0036 0.0167 0.0146
Onchocerca volvulus 0.003 0.0129 0.0284
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0047 0.025 0.0235
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0278 0.1859 0.1898
Schistosoma mansoni nuclear hormone receptor 0.0082 0.0494 0.0504
Trypanosoma cruzi 20S proteasome subunit 0.068 0.4673 0.466
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0066 0.0377 0.0366
Schistosoma mansoni lipoxygenase 0.0082 0.049 0.05
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0278 0.1859 0.1845
Echinococcus multilocularis phospholipase D1 0.0102 0.0632 0.0625
Schistosoma mansoni steroid hormone receptor ad4bp 0.0175 0.1139 0.1163
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.0606 0.0586
Echinococcus multilocularis cpg binding protein 0.003 0.0129 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0175 0.1139 0.112
Loa Loa (eye worm) steroid hormone receptor 0.0175 0.1139 0.112
Brugia malayi cytochrome P450 0.0021 0.0065 0.0044
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0082 0.0061
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0168 0.0143
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.0606 0.0586
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0166 0.0168
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0065 0.0043
Giardia lamblia 20S proteasome alpha subunit 6 0.0278 0.1859 0.1845
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0055 0.0035
Schistosoma mansoni growth factor receptor-bound protein 0.0015 0.0021 0.0022
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0051 0.003
Loa Loa (eye worm) hypothetical protein 0.0315 0.2118 0.2102
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.023 0.0214
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0021 0.0064 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0166 0.0168
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.0466 0.0456
Onchocerca volvulus 0.0078 0.0466 0.1528
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.1097 0.7591 0.7586
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0051 0.0032
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0193 0.1264 0.1273
Loa Loa (eye worm) hypothetical protein 0.0199 0.131 0.1292
Onchocerca volvulus 0.002 0.0055 0.0008
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0102 0.0629 0.0623
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1709 0.1744
Schistosoma mansoni tyrosine kinase 0.0157 0.1018 0.1039
Trichomonas vaginalis glucosylceramidase, putative 0.0168 0.1093 0.1115
Echinococcus multilocularis proteasome subunit beta type 6 0.0278 0.1859 0.1881
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0065 0.0039
Echinococcus multilocularis allatostatin A receptor 0.0078 0.0466 0.0456
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0182
Brugia malayi protein-tyrosine kinase 0.004 0.0199 0.0178
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0182
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0278 0.1859 0.184
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Onchocerca volvulus 0.0026 0.01 0.0177
Loa Loa (eye worm) proteasome subunit beta type 2 0.068 0.4673 0.4661
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0051 0.0052
Plasmodium vivax proteasome subunit beta type-1, putative 0.1097 0.7591 0.7744
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0102 0.0629 0.0608
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0278 0.1859 0.184
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0175 0.1139 0.1163
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0051 0.005
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0051 0.0032
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1413 0.9795 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0175 0.1139 0.112
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0278 0.1859 0.1898
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0193 0.1264 0.1246
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0175 0.1139 0.112
Echinococcus granulosus geminin 0.0168 0.1093 0.1098
Echinococcus granulosus neuropeptide s receptor 0.0535 0.3656 0.372
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0051 0.003
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0064 0.0064
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0168 0.0143
Echinococcus multilocularis multidrug resistance protein 1 0.0021 0.0064 0.0045
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0037 0.0174 0.0157
Brugia malayi multidrug resistance protein 3 0.0021 0.0064 0.0043
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0278 0.1859 0.1855
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0065 0.0039
Giardia lamblia 20S proteasome alpha subunit 1 0.0278 0.1859 0.1845
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0466 0.0456
Onchocerca volvulus Notchless protein homolog 0.0278 0.1859 0.6683
Brugia malayi nuclear receptor RXR 0.0082 0.0494 0.0474
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0278 0.1859 0.184
Onchocerca volvulus 0.0078 0.0466 0.1528
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Onchocerca volvulus Bile acid receptor homolog 0.0175 0.1139 0.4019
Echinococcus granulosus growth factor receptor bound protein 2 0.0015 0.0021 0.0001
Echinococcus granulosus proteasome subunit beta type 7 0.0278 0.1859 0.1881
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0166 0.0144
Schistosoma mansoni hypothetical protein 0.0068 0.0391 0.04
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0161 0.0138
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0026 0.0098 0.0048
Echinococcus multilocularis regulator of G protein signaling 7 0.0019 0.0051 0.0032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0179
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0082 0.0494 0.0485
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0051 0.0052
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0037 0.0174 0.0157
Brugia malayi G protein-coupled receptor F59B2.13 0.0078 0.0466 0.0445
Entamoeba histolytica P-glycoprotein-5 0.0021 0.0064 0.0014
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0064 0.0041
Schistosoma mansoni RAR-like nuclear receptor 0.0175 0.1139 0.1163
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0278 0.1859 0.1855
Brugia malayi Ets-domain containing protein 0.0072 0.042 0.04
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0278 0.1859 0.184
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1709 0.1744
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0278 0.1859 0.184
Echinococcus multilocularis phospholipase d3 0.0019 0.0053 0.0033
Brugia malayi Importin beta-1 subunit 0.0028 0.0116 0.0095
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0092 0.0563 0.0543
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0026 0.0098 0.0072
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0278 0.1859 0.1875
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0278 0.1859 0.184
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0278 0.1859 0.1875
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0026 0.0098 0.0075
Schistosoma mansoni sodium-dependent amino acid transporter 0.0041 0.0203 0.0207
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0026 0.0098 0.0079
Plasmodium falciparum transporter, putative 0.0041 0.0203 0.0179
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1097 0.7591 0.775
Plasmodium vivax proteasome subunit beta type-7, putative 0.0278 0.1859 0.1875
Echinococcus granulosus ecdysone induced protein 78C 0.0175 0.1139 0.1144
Echinococcus granulosus serotonin receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.003
Leishmania major cardiolipin synthetase, putative 0.0016 0.0032 0.001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0147
Leishmania major proteasome alpha 2 subunit, putative 0.0278 0.1859 0.184
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0064 0.0064
Echinococcus multilocularis c src tyrosine kinase 0.0019 0.0048 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0175 0.1139 0.112
Schistosoma mansoni thyroid hormone receptor 0.0299 0.2012 0.2054
Echinococcus multilocularis proteasome subunit alpha type 2 0.0278 0.1859 0.1881
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0278 0.1859 0.1841
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0193 0.1264 0.1291
Brugia malayi Tyrosine-protein kinase abl-1 0.0019 0.0048 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.015 0.0151
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0278 0.1859 0.184
Brugia malayi hypothetical protein 0.0016 0.0032 0.0011
Brugia malayi nuclear hormone receptor 0.0082 0.0494 0.0474
Leishmania major importin beta-1 subunit, putative 0.0023 0.0078 0.0056
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0147
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0092 0.0563 0.0575
Echinococcus granulosus proteasome prosome macropain 0.1413 0.9795 1
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0051 0.0032
Brugia malayi larval opioid receptor 0.0078 0.0466 0.0445
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0082 0.0494 0.0504
Schistosoma mansoni sodium/chloride dependent transporter 0.0041 0.0203 0.0207
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.01 0.0079
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0064 0.0064
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0016 0.0032 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0086
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0051 0.0052
Loa Loa (eye worm) hypothetical protein 0.0031 0.0136 0.0115
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0065 0.0039
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0136 0.0118
Trichomonas vaginalis glucosylceramidase, putative 0.0256 0.1709 0.1744
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0278 0.1859 0.184
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0278 0.1859 0.1855
Brugia malayi Serotonin receptor 0.0078 0.0466 0.0445
Schistosoma mansoni tyrosine kinase 0.0161 0.1044 0.1066
Echinococcus multilocularis lamin b receptor 0.0047 0.0246 0.0231
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0078 0.0466 0.0456
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0082 0.0494 0.0485
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0008
Schistosoma mansoni adenoreceptor 0.0078 0.0466 0.0475
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.025 0.0235
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0203 0.0207
Mycobacterium ulcerans proteasome PrcB 0.1413 0.9795 1
Brugia malayi proteasome subunit alpha type 1 0.0278 0.1859 0.1841
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0082 0.0494 0.0485
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0592 0.4055 0.4128
Trichomonas vaginalis abcb9, putative 0.0021 0.0064 0.0064
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0026 0.0098 0.0079
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0078 0.0466 0.0445
Echinococcus granulosus Nuclear hormone receptor HR96 0.0082 0.0494 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Echinococcus multilocularis NCK adaptor protein 0.0015 0.0021 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.0685 0.4704 0.4792
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0028 0.0005
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0021 0.0064 0.1879
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.0466 0.0475
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0065 0.0039
Schistosoma mansoni rab6-interacting 0.002 0.0055 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0051 0.003
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0161 0.1044 0.1048
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0051 0.0052
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0272 0.1823 0.1844
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0008
Echinococcus granulosus regulator of G protein signaling 7 0.0019 0.0051 0.0032
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0406 0.2755 0.2739
Trichomonas vaginalis abcb9, putative 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Echinococcus granulosus tm gpcr rhodopsin 0.09 0.6209 0.6332
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Toxoplasma gondii proteasome subunit beta type 2, putative 0.068 0.4673 0.4756
Brugia malayi Cytochrome P450 family protein 0.0059 0.033 0.0309
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0278 0.1859 0.1875
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0129 0.0112
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0182
Echinococcus granulosus biogenic amine 5HT receptor 0.0199 0.131 0.132
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0278 0.1859 0.184
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0175 0.1139 0.1144
Trichomonas vaginalis ABC transporter, putative 0.0021 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0047 0.025 0.0235
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0278 0.1859 0.1875
Schistosoma mansoni hypothetical protein 0.0031 0.0136 0.0138
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0278 0.1859 0.1841
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0278 0.1859 0.1881
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0023 0.0001
Plasmodium falciparum proteasome subunit beta type-5 0.1413 0.9795 1
Onchocerca volvulus Glucosylceramidase homolog 0.0168 0.1093 0.3851
Brugia malayi hypothetical protein 0.0019 0.0051 0.003
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.0466 0.0456
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Brugia malayi hypothetical protein 0.0026 0.01 0.0079
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0098 0.0075
Schistosoma mansoni tyrosine kinase 0.0047 0.025 0.0255
Plasmodium vivax cardiolipin synthetase, putative 0.0016 0.0032 0.0005
Echinococcus granulosus FTZ F1 alpha 0.0175 0.1139 0.1144
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0086 0.0086
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0278 0.1859 0.1841
Brugia malayi sulfakinin receptor protein 0.0078 0.0466 0.0445
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0278 0.1859 0.1881
Schistosoma mansoni amine GPCR 0.0078 0.0466 0.0475
Schistosoma mansoni Lamin B receptor (ERG24) 0.0047 0.0246 0.0252
Echinococcus multilocularis neuropeptide receptor A26 0.0535 0.3656 0.372
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0051 0.0032
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.1097 0.7591 0.7586
Schistosoma mansoni sodium/chloride dependent transporter 0.024 0.1595 0.1629
Echinococcus multilocularis jun protein 0.0083 0.0501 0.0491
Schistosoma mansoni tyrosine kinase 0.0298 0.2001 0.2043
Brugia malayi regulator of G-protein signaling egl-10 0.0019 0.0051 0.003
Mycobacterium tuberculosis Conserved protein 0.0036 0.0168 0.0143
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0078 0.0466 0.0475
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0182
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0166 0.0144
Schistosoma mansoni histamine h1 receptor 0.0078 0.0466 0.0475
Trypanosoma cruzi cardiolipin synthetase, putative 0.0036 0.0167 0.0145
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0278 0.1859 0.1898
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0021 0.0064 0.0038
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0278 0.1859 0.184
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0102 0.0629 0.0643
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0064 0.0037
Echinococcus multilocularis peroxidasin 0.0026 0.01 0.0082
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.01 0.0079
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0037 0.0174 0.0153
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.025 0.0235
Entamoeba histolytica P-glycoprotein-2 0.0021 0.0064 0.0014
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.023 0.0208
Echinococcus multilocularis G protein coupled receptor 139 0.0078 0.0466 0.0456
Echinococcus granulosus NCK adaptor protein 0.0015 0.0021 0.0001
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0078 0.0466 0.0475
Brugia malayi Nuclear hormone receptor-like 1 0.0175 0.1139 0.112
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0406 0.2755 0.2739
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0102 0.0629 0.0608
Loa Loa (eye worm) hypothetical protein 0.0066 0.0383 0.0362
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0078 0.0466 0.0475
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Schistosoma mansoni tyrosine kinase 0.0097 0.0594 0.0606
Giardia lamblia 20S proteasome alpha subunit 4 0.0278 0.1859 0.1845
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0016 0.0032 0.0033
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0078 0.0466 0.0475
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0028 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0175 0.1139 0.112
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0168 0.0171
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0168 0.0151
Loa Loa (eye worm) TK/EGFR protein kinase 0.0298 0.2001 0.1984
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0184 0.0186
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0182
Brugia malayi neuropeptide F receptor 0.0078 0.0466 0.0445
Echinococcus multilocularis g protein coupled receptor 0.0078 0.0466 0.0456
Onchocerca volvulus 0.0078 0.0466 0.1528
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0175 0.1139 0.1144
Leishmania major sterol C-24 reductase, putative 0.0047 0.0246 0.0224
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0278 0.1859 0.184
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0026 0.0098 0.01
Echinococcus multilocularis neuropeptides capa receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0078 0.0466 0.0445
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0136 0.0118
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0023 0.0002
Plasmodium vivax amine transporter, putative 0.0041 0.0203 0.0179
Schistosoma mansoni z-protein (S1r protein) 0.0019 0.0051 0.0052
Brugia malayi Pre-SET motif family protein 0.0207 0.1366 0.1347
Onchocerca volvulus Protein ultraspiracle homolog 0.0175 0.1139 0.4019
Loa Loa (eye worm) phospholipase D 0.0019 0.0053 0.0032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1513 0.1521
Echinococcus granulosus tyrosine protein kinase Fyn 0.0047 0.025 0.0235
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0102 0.0629 0.0641
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0041 0.0203 0.0207
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0051 0.0032
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0179
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0102 0.0629 0.0616
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0064 0.0042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0117 0.0096
Echinococcus granulosus alpha 1A adrenergic receptor 0.0078 0.0466 0.0456
Brugia malayi nuclear receptor NHR-88 0.0175 0.1139 0.112
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0278 0.1859 0.184
Brugia malayi Proteasome A-type and B-type family protein 0.0278 0.1859 0.1841
Onchocerca volvulus 0.0078 0.0466 0.1528
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0278 0.1859 0.1898
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0097 0.0594 0.0587
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0278 0.1859 0.184
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0041 0.0203 0.0187
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0278 0.1859 0.1855
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0278 0.1859 0.1898
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0166 0.0168
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0021 0.0064 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0026 0.0098 0.0075
Mycobacterium leprae Probable lipase LipE 0.0036 0.0168 0.0105
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0168 0.0146
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0064 0.0042
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0193 0.1264 0.1273
Echinococcus granulosus neuropeptide FF receptor 2 0.0078 0.0466 0.0456
Onchocerca volvulus 0.0078 0.0466 0.1528
Brugia malayi hypothetical protein 0.0092 0.0563 0.0543
Schistosoma mansoni hypothetical protein 0.0067 0.0388 0.0396
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.023 0.0233
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0182
Echinococcus granulosus epidermal growth factor receptor 0.0161 0.1044 0.1048
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0168 0.017
Mycobacterium ulcerans proteasome PrcA 0.0278 0.1859 0.1843
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Brugia malayi nuclear receptor NHR-88 0.0082 0.0494 0.0474
Echinococcus multilocularis neuropeptide FF receptor 2 0.0078 0.0466 0.0456
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0278 0.1859 0.1881
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0168 0.0143
Echinococcus granulosus phospholipase d3 0.0019 0.0053 0.0033
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1413 0.9795 1
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.2755 0.2798
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0026 0.0098 0.0072
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0037 0.0174 0.0153
Echinococcus multilocularis proteasome subunit beta type 7 0.0278 0.1859 0.1881
Echinococcus granulosus sodium and chloride dependent glycine 0.0041 0.0203 0.0187
Loa Loa (eye worm) polyprenyl synthetase 0.0026 0.0098 0.0077
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0175 0.1139 0.112
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0278 0.1859 0.1841
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0051 0.0032
Trypanosoma cruzi sterol C-24 reductase, putative 0.0047 0.0246 0.0224
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0161 0.014
Loa Loa (eye worm) hypothetical protein 0.0082 0.0494 0.0474
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0466 0.0475
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.0466 0.0456
Leishmania major proteasome alpha 7 subunit, putative 0.0278 0.1859 0.184
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0051 0.0052
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0166 0.0144
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0064 0.0064
Brugia malayi Steroid receptor seven-up type 2 0.0175 0.1139 0.112
Schistosoma mansoni multidrug resistance protein 0.0021 0.0064 0.0066
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Schistosoma mansoni cpg binding protein 0.003 0.0129 0.0131
Brugia malayi beta-NAC-like protein 0.0035 0.0161 0.014
Echinococcus multilocularis neuropeptide s receptor 0.0535 0.3656 0.372
Loa Loa (eye worm) hypothetical protein 0.0737 0.5071 0.5061
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0048 0.0025
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0175 0.1139 0.4019
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0168 0.0146
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0116 0.009
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0019 0.0051 0.003
Schistosoma mansoni retinoic acid receptor RXR 0.0272 0.1823 0.1861
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0278 0.1859 0.1875
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0129 0.0132
Brugia malayi Proteasome A-type and B-type family protein 0.1413 0.9795 0.9794
Trypanosoma brucei proteasome beta 7 subunit 0.0278 0.1859 0.184
Brugia malayi Dopamine receptor protein 1 0.0078 0.0466 0.0445
Brugia malayi hypothetical protein 0.0036 0.0168 0.0147
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0278 0.1859 0.1875
Brugia malayi 20S proteasome alpha5 subunit 0.0278 0.1859 0.1841
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0026 0.0098 0.0048
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus importin subunit beta 1 0.0028 0.0116 0.0098
Echinococcus granulosus somatostatin receptor 0.0078 0.0466 0.0456
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0065 0.0046
Loa Loa (eye worm) hypothetical protein 0.0092 0.0563 0.0543
Onchocerca volvulus Peroxidase homolog 0.0026 0.01 0.0177
Mycobacterium ulcerans lipase LipD 0.0036 0.0168 0.0105
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0078 0.0466 0.0456
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0168 0.0143
Leishmania major GTP-binding protein, putative 0.0021 0.0064 0.0041
Brugia malayi hypothetical protein 0.002 0.0055 0.0034
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.024 0.1595 0.1629
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.015 0.0151
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0278 0.1859 0.1898
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0078 0.0466 0.0475
Schistosoma mansoni nuclear receptor 0.0082 0.0494 0.0504
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0182
Loa Loa (eye worm) hypothetical protein 0.0086 0.0517 0.0497
Brugia malayi putative neuropeptide receptor NPR1 0.0078 0.0466 0.0445
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0092 0.0563 0.0575
Giardia lamblia 20S proteasome alpha subunit 7 0.0278 0.1859 0.1845
Echinococcus granulosus rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Schistosoma mansoni thyroid hormone receptor 0.0299 0.2012 0.2054
Echinococcus multilocularis nuclear receptor nhr 48 0.0082 0.0494 0.0485
Schistosoma mansoni biogenic amine receptor 0.0078 0.0466 0.0475
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1413 0.9795 0.9794
Schistosoma mansoni neuropeptide F-like receptor 0.0078 0.0466 0.0475
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0041 0.0203 0.0187
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0278 0.1859 0.1841
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0256 0.1709 0.1692
Schistosoma mansoni hypothetical protein 0.0031 0.0136 0.0138
Brugia malayi Furin-like cysteine rich region family protein 0.0298 0.2001 0.1984
Entamoeba histolytica phospholipase D, putative 0.0102 0.0632 0.0596
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0175 0.1139 0.112
Toxoplasma gondii proteasome subunit beta type 1, putative 0.1097 0.7591 0.7744
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0019 0.0048 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0051 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.023 0.0233
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0041 0.0203 0.0207
Brugia malayi PXA domain containing protein 0.0023 0.0082 0.0061
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0168 0.0143
Plasmodium vivax proteasome subunit beta type-6, putative 0.0278 0.1859 0.1875
Schistosoma mansoni voltage-gated potassium channel 0.004 0.0197 0.0202
Echinococcus multilocularis thyroid hormone receptor alpha 0.0299 0.2012 0.2038
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0161 0.0138
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0278 0.1859 0.1855
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0015 0.0021 0.0022
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0127 0.0128
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0278 0.1859 0.1855
Loa Loa (eye worm) hypothetical protein 0.0092 0.0563 0.0543
Brugia malayi putative neuropeptide receptor 0.0078 0.0466 0.0445
Echinococcus granulosus tyrosine protein kinase Lyn 0.0047 0.025 0.0235
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.068 0.4673 0.4743
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0078 0.0466 0.0456
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0129 0.0112
Schistosoma mansoni loxhd1 0.002 0.0055 0.0056
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.1097 0.7591 0.7751
Trypanosoma cruzi polyprenyl synthase, putative 0.0026 0.0098 0.0075
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0008
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Brugia malayi proteasome subunit beta type 3 0.0278 0.1859 0.1841
Entamoeba histolytica Ran family GTPase 0.0021 0.0064 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.015 0.0151
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0028 0.0005
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0278 0.1859 0.1875
Brugia malayi Phospholipase d protein 1 0.0102 0.0632 0.0612
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0175 0.1139 0.112
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0055 0.0035
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0092 0.0563 0.0555
Schistosoma mansoni biogenic amine receptor 0.0078 0.0466 0.0475
Onchocerca volvulus 0.0078 0.0466 0.1528
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0175 0.1139 0.112
Toxoplasma gondii proteasome subunit beta type, putative 0.1413 0.9795 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.023 0.0235
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0051 0.0052
Echinococcus granulosus neuropeptide Y receptor 0.0078 0.0466 0.0456
Schistosoma mansoni amine GPCR 0.0078 0.0466 0.0475
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) hypothetical protein 0.0081 0.0485 0.0464
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0051 0.003
Brugia malayi G-protein coupled receptor 0.0078 0.0466 0.0445
Onchocerca volvulus 0.002 0.0055 0.0008
Echinococcus granulosus neuropeptides capa receptor 0.0078 0.0466 0.0456
Leishmania major proteasome alpha 1 subunit, putative 0.0278 0.1859 0.184
Schistosoma mansoni neuropeptide receptor 0.0078 0.0466 0.0475
Brugia malayi follicle stimulating hormone receptor 0.0078 0.0466 0.0445
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0078 0.0078
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0078 0.0466 0.0445
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.0736 0.0732
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0278 0.1859 0.184
Echinococcus multilocularis somatostatin receptor 0.0078 0.0466 0.0456
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0026 0.0098 0.0072
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0021 0.0064 0.0043
Echinococcus granulosus lamin b receptor 0.0047 0.0246 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0051 0.005
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0278 0.1859 0.1896
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0078 0.0466 0.0445
Echinococcus granulosus g-protein coupled receptor 0.0078 0.0466 0.0456
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0041 0.0203 0.0182
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0175 0.1139 0.1163
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0051 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0104 0.0105
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0278 0.1859 0.184
Echinococcus multilocularis neuropeptide Y receptor 0.0078 0.0466 0.0456
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0041 0.0203 0.0187
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0278 0.1859 0.1898
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0168 0.0143
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0147 0.0129
Echinococcus granulosus tyrosine protein kinase Src64B 0.0047 0.025 0.0235
Loa Loa (eye worm) norepinephrine transporter 0.024 0.1595 0.1577
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0026 0.0098 0.0079
Schistosoma mansoni hypothetical protein 0.0168 0.1093 0.1116
Onchocerca volvulus 0.0041 0.0203 0.0555
Echinococcus multilocularis rhodopsin orphan GPCR 0.0078 0.0466 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.015 0.0151
Brugia malayi nuclear hormone receptor family member odr-7 0.0082 0.0494 0.0474
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0278 0.1859 0.1898
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0278 0.1859 0.1855
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0066 0.0377 0.0358
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0161 0.0136
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0278 0.1859 0.1855
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0021 0.0064 0.0064
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.01 0.0079
Plasmodium vivax multidrug resistance protein 1, putative 0.0021 0.0064 0.0038
Echinococcus multilocularis sodium and chloride dependent glycine 0.0041 0.0203 0.0187
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0026 0.0098 0.0072
Echinococcus multilocularis fmrfamide receptor 0.0078 0.0466 0.0456
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0173 0.0156
Loa Loa (eye worm) nuclear receptor NHR-67 0.0082 0.0494 0.0474
Schistosoma mansoni amine GPCR 0.0407 0.2763 0.2821
Onchocerca volvulus 0.0026 0.01 0.0177
Entamoeba histolytica hypothetical protein 0.0036 0.0168 0.012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0078 0.0466 0.0456
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0064 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0103 0.0103
Brugia malayi hypothetical protein 0.0078 0.0466 0.0445
Leishmania major p-glycoprotein 0.0021 0.0064 0.0042
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0078 0.0466 0.0456
Brugia malayi Nuclear hormone receptor E75 0.0082 0.0494 0.0474
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.015 0.0125
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0278 0.1859 0.1896
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0136 0.0118
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0278 0.1859 0.1875
Brugia malayi Nuclear hormone receptor-like 1 0.0092 0.0563 0.0543
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0136 0.0115
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0278 0.1859 0.1875
Loa Loa (eye worm) hypothetical protein 0.0036 0.0168 0.0147
Loa Loa (eye worm) hypothetical protein 0.0067 0.0388 0.0368
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0278 0.1859 0.1855
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0166 0.0168
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0175 0.1139 0.1144
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0021 0.0064 0.0045
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0078 0.0466 0.0456
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0161 0.0136
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Schistosoma mansoni hypothetical protein 0.0125 0.0791 0.0808
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0182
Loa Loa (eye worm) hypothetical protein 0.0078 0.0466 0.0445
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0278 0.1859 0.1875
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.023 0.0208
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0078 0.0466 0.0445
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0065 0.0039
Leishmania major proteasome beta-1 subunit, putative 0.0278 0.1859 0.184
Plasmodium vivax SET domain protein, putative 0.003 0.0129 0.0104
Entamoeba histolytica hypothetical protein 0.0036 0.0168 0.012
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0278 0.1859 0.1875
Onchocerca volvulus 0.0026 0.01 0.0177
Echinococcus multilocularis neuropeptide receptor 0.0078 0.0466 0.0456
Brugia malayi Blistered cuticle protein 3 0.0026 0.01 0.0079
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0082 0.0494 0.1633
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0047 0.025 0.0235
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0051 0.0052
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0026 0.0098 0.0033
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0051 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0065 0.0039
Echinococcus granulosus microtubule associated protein 2 0.0685 0.4704 0.4792
Loa Loa (eye worm) hypothetical protein 0.0026 0.01 0.0079
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0082 0.0494 0.0485
Loa Loa (eye worm) beta-lactamase 0.0036 0.0168 0.0147
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0066 0.0377 0.0356
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0278 0.1859 0.1898
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0078 0.0466 0.0475
Schistosoma mansoni cpg binding protein 0.0028 0.0117 0.012
Leishmania major hypothetical protein, conserved 0.0406 0.2755 0.2739
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0066 0.0377 0.0358
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0041 0.0203 0.0182
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0019 0.0048 0.0049
Loa Loa (eye worm) hypothetical protein 0.0175 0.1139 0.112
Entamoeba histolytica hypothetical protein 0.0023 0.0078 0.0028

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 1900 nM Displacement of [3H]Lu AE93103 from human NK3 receptor expressed in BHK cells ChEMBL. 21292483

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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