Detailed information for compound 1503872

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 486.556 | Formula: C30H30O6
  • H donors: 0 H acceptors: 3 LogP: 7.94 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H]1CCCCCCCc2c(C(=O)O1)c(cc(c2)OC(=O)c1ccccc1)OC(=O)c1ccccc1
  • InChi: 1S/C30H30O6/c1-21-13-7-3-2-4-8-18-24-19-25(35-28(31)22-14-9-5-10-15-22)20-26(27(24)30(33)34-21)36-29(32)23-16-11-6-12-17-23/h5-6,9-12,14-17,19-21H,2-4,7-8,13,18H2,1H3/t21-/m1/s1
  • InChiKey: PGPVMDBUSYDCKD-OAQYLSRUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0252 0.1636 0.1636
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0252 0.1636 0.1636
Loa Loa (eye worm) PAS-3 protein 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0998 0.7678 0.7678
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0618 0.4602 0.4602
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1284 1 1
Toxoplasma gondii thioredoxin reductase 0.0068 0.014 0.014
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0998 0.7678 0.7678
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.1284 1 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0998 0.7678 0.7678
Leishmania major proteasome beta-1 subunit, putative 0.0252 0.1636 0.1636
Brugia malayi Proteasome subunit alpha type 7-1 0.0252 0.1636 0.1636
Brugia malayi proteasome subunit alpha type 6 0.0252 0.1636 0.1636
Echinococcus multilocularis thioredoxin glutathione reductase 0.0068 0.014 0.014
Plasmodium vivax proteasome subunit beta type-2, putative 0.0618 0.4602 0.4602
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.1284 1 1
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0252 0.1636 0.1636
Toxoplasma gondii proteasome subunit alpha1, putative 0.0252 0.1636 0.1636
Brugia malayi Proteasome A-type and B-type family protein 0.0252 0.1636 0.1636
Brugia malayi glutathione reductase 0.0068 0.014 0.014
Toxoplasma gondii proteasome subunit alpha type, putative 0.0252 0.1636 0.1636
Giardia lamblia Proteasome subunit beta type 5 precursor 0.1284 1 1
Echinococcus granulosus Proteasome subunit alpha type 7 0.0252 0.1636 0.1636
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0252 0.1636 0.1636
Brugia malayi proteasome subunit beta type 2 0.0618 0.4602 0.4602
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome subunit beta type 7 0.0252 0.1636 0.1636
Toxoplasma gondii proteasome beta subunit 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0618 0.4602 0.4602
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0252 0.1636 0.1636
Echinococcus multilocularis leukotriene A 4 hydrolase 0.095 0.729 0.729
Giardia lamblia Proteasome subunit beta type 1 0.0998 0.7678 0.7224
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0252 0.1636 0.1636
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0252 0.1636 0.1636
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0998 0.7678 0.7678
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0618 0.4602 0.4602
Trypanosoma brucei trypanothione reductase 0.0068 0.014 0.014
Echinococcus multilocularis proteasome subunit alpha type 6 0.0252 0.1636 0.1636
Toxoplasma gondii peptidase, T1 family protein 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0252 0.1636 0.1636
Leishmania major proteasome alpha 3 subunit, putative 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome subunit beta type 6 0.0252 0.1636 0.1636
Toxoplasma gondii proteasome subunit beta type, putative 0.1284 1 1
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome subunit alpha type 2 0.0252 0.1636 0.1636
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0252 0.1636 0.1636
Giardia lamblia Proteasome subunit beta type 2 0.0618 0.4602 0.3546
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0618 0.4602 0.4602
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome prosome macropain 0.1284 1 1
Leishmania major proteasome beta 5 subunit, putative 0.1284 1 1
Leishmania major proteasome beta 7 subunit, putative 0.0252 0.1636 0.1636
Brugia malayi 20S proteasome alpha5 subunit 0.0252 0.1636 0.1636
Trypanosoma cruzi 20S proteasome subunit 0.0618 0.4602 0.4602
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0252 0.1636 0.1636
Mycobacterium ulcerans proteasome PrcB 0.1284 1 1
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0252 0.1636 0.1636
Mycobacterium leprae proteasome (beta subunit) PrcB 0.1284 1 1
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0252 0.1636 0.1636
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0252 0.1636 0.1636
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0252 0.1636 0.1636
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0252 0.1636 0.1636
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0252 0.1636 0.1636
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0618 0.4602 0.4602
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.095 0.729 0.729
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0618 0.4602 0.4602
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0252 0.1636 0.1636
Leishmania major trypanothione reductase 0.0068 0.014 0.014
Trypanosoma brucei proteasome beta 7 subunit 0.0252 0.1636 0.1636
Brugia malayi proteasome subunit alpha type 4 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0252 0.1636 0.1636
Leishmania major proteasome beta 2 subunit, putative 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome subunit beta type 6 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0998 0.7678 0.7678
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.1284 1 1
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0998 0.7678 0.7678
Brugia malayi proteasome subunit beta type 3 0.0252 0.1636 0.1636
Brugia malayi Proteasome A-type and B-type family protein 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome beta 6 subunit 0.0998 0.7678 0.7678
Leishmania major proteasome alpha 7 subunit, putative 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.1284 1 1
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Leishmania major proteasome alpha 1 subunit, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0252 0.1636 0.1636
Loa Loa (eye worm) glutathione reductase 0.0068 0.014 0.014
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit beta type-5, putative 0.1284 1 1
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0252 0.1636 0.1636
Loa Loa (eye worm) thioredoxin reductase 0.0068 0.014 0.014
Echinococcus granulosus thioredoxin glutathione reductase 0.0068 0.014 0.014
Leishmania major proteasome beta 3 subunit, putative 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit beta type-4, putative 0.0252 0.1636 0.1636
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0252 0.1636 0.1636
Echinococcus granulosus leukotriene A 4 hydrolase 0.095 0.729 0.729
Echinococcus granulosus Proteasome subunit alpha beta 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit beta type-6, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome subunit beta type 7 0.0252 0.1636 0.1636
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0618 0.4602 0.4602
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0252 0.1636 0.1636
Leishmania major proteasome alpha 1 subunit, putative 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0252 0.1636 0.1636
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0618 0.4602 0.4602
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0252 0.1636 0.1636
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0252 0.1636 0.5
Plasmodium vivax thioredoxin reductase, putative 0.0068 0.014 0.014
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit beta type-5 0.1284 1 1
Loa Loa (eye worm) leukotriene A4 hydrolase 0.095 0.729 0.729
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0252 0.1636 0.1636
Plasmodium falciparum thioredoxin reductase 0.0068 0.014 0.014
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0252 0.1636 0.1636
Brugia malayi hypothetical protein 0.0437 0.3131 0.3131
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0618 0.4602 0.4602
Brugia malayi proteasome subunit beta type 1 0.0998 0.7678 0.7678
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Leishmania major proteasome alpha 2 subunit, putative 0.0252 0.1636 0.1636
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0998 0.7678 0.7678
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome subunit alpha type 2 0.0252 0.1636 0.1636
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0998 0.7678 0.7678
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0252 0.1636 0.1517
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0252 0.1636 0.1636
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.1284 1 1
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0252 0.1636 0.1636
Toxoplasma gondii proteasome subunit 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit beta type-7, putative 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit beta type-4 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome subunit beta t family 0.0252 0.1636 0.1636
Toxoplasma gondii heat shock protein hslv, putative 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0252 0.1636 0.1636
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0998 0.7678 0.7678
Brugia malayi Proteasome subunit alpha type 1 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit beta type-1, putative 0.0998 0.7678 0.7678
Echinococcus granulosus subfamily T1A non peptidase ue 0.0252 0.1636 0.1636
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0252 0.1636 0.1636
Leishmania major proteasome beta 2 subunit, putative 0.0618 0.4602 0.4602
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0252 0.1636 0.1636
Brugia malayi proteasome subunit alpha type 3 0.0252 0.1636 0.1636
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0252 0.1636 0.1636
Echinococcus granulosus proteasome subunit alpha type 6 0.0252 0.1636 0.1636
Brugia malayi proteasome subunit alpha type 2 0.0252 0.1636 0.1636
Plasmodium vivax glutathione reductase, putative 0.0068 0.014 0.014
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit beta type-3, putative 0.0252 0.1636 0.1636
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit beta type 1 0.0998 0.7678 0.7678
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0252 0.1636 0.1636
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0252 0.1636 0.1636
Brugia malayi proteasome subunit alpha type 1 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0252 0.1636 0.1636
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0618 0.4602 0.4602
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0252 0.1636 0.1636
Plasmodium falciparum glutathione reductase 0.0068 0.014 0.014
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0252 0.1636 0.1636
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit beta type 3 0.0252 0.1636 0.1636
Brugia malayi Thioredoxin reductase 0.0068 0.014 0.014
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0998 0.7678 0.7678
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0252 0.1636 0.1636
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0252 0.1636 0.1636
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0618 0.4602 0.4602
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0252 0.1636 0.1636
Loa Loa (eye worm) proteasome subunit beta type 2 0.0618 0.4602 0.4602
Mycobacterium ulcerans proteasome PrcA 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0252 0.1636 0.1636
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0252 0.1636 0.1636
Leishmania major proteasome alpha 7 subunit, putative 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.1284 1 1
Trypanosoma brucei proteasome alpha 7 subunit 0.0252 0.1636 0.1636
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0252 0.1636 0.1636
Trypanosoma cruzi trypanothione reductase, putative 0.0068 0.014 0.014
Onchocerca volvulus Notchless protein homolog 0.0252 0.1636 1
Brugia malayi Proteasome A-type and B-type family protein 0.0252 0.1636 0.1636
Trypanosoma brucei proteasome subunit beta type-5, putative 0.1284 1 1
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0252 0.1636 0.1636
Echinococcus multilocularis proteasome (prosome, macropain) 0.1284 1 1
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0252 0.1636 0.1636

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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