Detailed information for compound 150589

Basic information

Technical information
  • TDR Targets ID: 150589
  • Name: 2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]ace tic acid
  • MW: 203.196 | Formula: C7H13N3O4
  • H donors: 4 H acceptors: 4 LogP: -4.82 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=O)CC[C@@H](C(=O)NCC(=O)O)N
  • InChi: 1S/C7H13N3O4/c8-4(1-2-5(9)11)7(14)10-3-6(12)13/h4H,1-3,8H2,(H2,9,11)(H,10,14)(H,12,13)/t4-/m0/s1
  • InChiKey: JEFZIKRIDLHOIF-BYPYZUCNSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[(2S)-2,5-diamino-5-oxo-pentanoyl]amino]acetic acid
  • 2-[[(2S)-2,5-diamino-1,5-dioxopentyl]amino]acetic acid
  • 2-[[(2S)-2,5-bis(azanyl)-5-oxo-pentanoyl]amino]ethanoic acid
  • 2-[[(2S)-2,5-diamino-5-keto-pentanoyl]amino]acetic acid
  • 2-[[(2S)-5-amino-2-azaniumyl-5-oxopentanoyl]amino]acetate
  • 2-[[(2S)-5-amino-2-azaniumyl-5-oxo-pentanoyl]amino]acetate
  • 2-[[(2S)-5-amino-2-ammonio-1,5-dioxopentyl]amino]acetate
  • 2-[[(2S)-2-azaniumyl-5-azanyl-5-oxo-pentanoyl]amino]ethanoate
  • 2-[[(2S)-5-amino-2-ammonio-5-keto-pentanoyl]amino]acetate
  • 2-[[(2S)-2,5-diamino-5-oxo-pentanoyl]amino]ethanoic acid
  • 2-[[(2S)-5-amino-2-azaniumyl-5-oxo-pentanoyl]amino]ethanoate
  • ZINC01581634

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi DNA damage repair protein, putative 0.0026 0.0548 0.0896
Echinococcus multilocularis musashi 0.0026 0.0547 0.0793
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0059 0.001
Onchocerca volvulus 0.0027 0.0581 0.0422
Brugia malayi hypothetical protein 0.0014 0.0059 0.001
Schistosoma mansoni flap endonuclease-1 0.0023 0.0414 0.0433
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0581 0.0848
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0264 0.0252
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.3243 0.5176
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.13 0.1257
Loa Loa (eye worm) hypothetical protein 0.0236 0.91 0.9096
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.4238 0.421
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0581 0.0637
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Leishmania major DNA polymerase kappa, putative 0.0098 0.346 0.8724
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0581 0.0535
Echinococcus multilocularis geminin 0.0165 0.6211 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0581 0.0848
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0015 0.0105 0.0303
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0581 0.0422
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0581 0.0535
Onchocerca volvulus 0.0029 0.0661 0.0513
Echinococcus multilocularis lamin dm0 0.0026 0.0547 0.0793
Brugia malayi hypothetical protein 0.0014 0.0059 0.001
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Loa Loa (eye worm) hypothetical protein 0.0026 0.0521 0.0474
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.13 0.2017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0059 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.2386 0.4611
Echinococcus granulosus p2X purinoceptor 4 0.0157 0.5888 0.9475
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0547 0.05
Plasmodium vivax heat shock protein 90, putative 0.003 0.0689 0.0928
Brugia malayi ImpB/MucB/SamB family protein 0.011 0.3951 0.3921
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0581 0.0637
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0581 0.0535
Echinococcus granulosus dna polymerase eta 0.011 0.3951 0.6326
Schistosoma mansoni ets-related 0.0215 0.8247 1
Echinococcus granulosus lamin dm0 0.0026 0.0547 0.0793
Plasmodium falciparum flap endonuclease 1 0.0025 0.0514 0.0649
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.1303 0.2936
Loa Loa (eye worm) hypothetical protein 0.0033 0.0834 0.0789
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.13 0.2017
Loa Loa (eye worm) heat shock protein 75 0.003 0.0689 0.0643
Trypanosoma cruzi DNA damage repair protein, putative 0.0026 0.0548 0.0896
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Schistosoma mansoni terminal deoxycytidyl transferase 0.0085 0.2935 0.3512
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.1303 0.2421
Brugia malayi Ets-domain containing protein 0.0071 0.2364 0.2326
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3243 0.3272
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0548 0.0896
Echinococcus granulosus lysine specific demethylase 5A 0.0034 0.0877 0.133
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.2667 0.5177
Giardia lamblia DNA damage repair protein 0.0026 0.0548 0.089
Trypanosoma brucei DNA polymerase kappa, putative 0.0098 0.346 0.6781
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0105 0.0056
Brugia malayi hypothetical protein 0.0032 0.0771 0.0725
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0104 0.0073
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.234 0.3708
Plasmodium vivax ataxin-2 like protein, putative 0.0049 0.1482 0.2187
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0634 0.0702
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0537 0.0686
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.3243 0.321
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.1303 0.2421
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0661 0.0736
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0581 0.0637
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0041 0.1154 0.1666
Echinococcus granulosus endoplasmin 0.0042 0.119 0.1839
Brugia malayi nuclear receptor RXR 0.0014 0.0059 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0581 0.0535
Onchocerca volvulus 0.0026 0.0547 0.0384
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0581 0.0535
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Brugia malayi Pre-SET motif family protein 0.0203 0.7749 0.7738
Schistosoma mansoni hypothetical protein 0.0165 0.6211 0.7514
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0064 0.2072 0.5116
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0496 0.0791
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.1464 0.1422
Echinococcus granulosus geminin 0.0165 0.6211 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0547 0.05
Trypanosoma cruzi DNA polymerase eta, putative 0.011 0.3951 0.7773
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Schistosoma mansoni tsg101-related 0.0057 0.1785 0.2108
Plasmodium falciparum DNA repair protein REV1, putative 0.0026 0.0548 0.0704
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0085 0.2935 0.29
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0104 0.0073
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0105 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3243 0.3272
Loa Loa (eye worm) hypothetical protein 0.011 0.3951 0.3921
Schistosoma mansoni hypothetical protein 0.0015 0.0104 0.0055
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0581 0.0848
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0283 0.0361
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0581 0.0848
Trypanosoma cruzi heat shock protein, putative 0.003 0.0689 0.1181
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0064 0.2072 0.3977
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.2386 0.4611
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0105 0.0075
Onchocerca volvulus Huntingtin homolog 0.0119 0.4345 0.4665
Loa Loa (eye worm) heat shock protein 90 0.0045 0.1303 0.126
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0362 0.0519
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0581 0.0637
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.1303 0.2421
Trichomonas vaginalis DNA polymerase eta, putative 0.0137 0.5053 0.5428
Trichomonas vaginalis DNA helicase recq, putative 0.0047 0.1387 0.1061
Brugia malayi Endoplasmin precursor 0.0045 0.1303 0.126
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0264 0.0216
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0104 0.0073
Brugia malayi Bromodomain containing protein 0.0028 0.0634 0.0588
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0581 0.0535
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0581 0.0535
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.2364 0.3746
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.5053 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0581 0.0848
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0581 0.0535
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0105 0.0075
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0661 0.0736
Onchocerca volvulus 0.023 0.8892 0.9791
Schistosoma mansoni lamin 0.0026 0.0547 0.0596
Echinococcus multilocularis heat shock protein 90 0.0038 0.1039 0.1592
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0801 0.0364
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.1482 0.2187
Trichomonas vaginalis rotamase, putative 0.0064 0.2072 0.1878
Trypanosoma brucei DNA polymerase IV, putative 0.0137 0.5053 1
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0065 0.2135 0.2097
Plasmodium falciparum heat shock protein 90, putative 0.017 0.6404 1
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0362 0.0519
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.3243 0.6343
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0581 0.0637
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0264 0.0216
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0548 0.0896
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0877 0.1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0547 0.05
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3243 0.3272
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.13 0.1515
Echinococcus granulosus p2X purinoceptor 4 0.0157 0.5888 0.9475
Loa Loa (eye worm) hypothetical protein 0.0027 0.0581 0.0535
Schistosoma mansoni hypothetical protein 0.0022 0.0375 0.0386
Schistosoma mansoni endoplasmin 0.0045 0.1303 0.1519
Brugia malayi Ets-domain containing protein 0.0071 0.2364 0.2326
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Treponema pallidum heat shock protein 90 0.0042 0.119 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.13 0.1515
Schistosoma mansoni tsg101-related 0.0057 0.1785 0.2108
Loa Loa (eye worm) hypothetical protein 0.0027 0.0581 0.0535
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3243 0.3272
Echinococcus multilocularis dna polymerase eta 0.011 0.3951 0.6326
Loa Loa (eye worm) hypothetical protein 0.0014 0.0059 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.134 0.1005
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.1303 0.2936
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0581 0.0535
Brugia malayi MH2 domain containing protein 0.0117 0.4238 0.421
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0581 0.0848
Echinococcus multilocularis dna polymerase kappa 0.0137 0.5053 0.8117
Echinococcus multilocularis jumonji domain containing protein 0.0039 0.1087 0.1672
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.3243 0.5176
Trypanosoma brucei polo-like protein kinase 0.0092 0.3243 0.6343
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0042 0.119 0.344
Loa Loa (eye worm) hypothetical protein 0.0029 0.0661 0.0615
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3243 0.3272
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Echinococcus granulosus intermediate filament protein 0.0026 0.0547 0.0793
Onchocerca volvulus 0.0026 0.0521 0.0354
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0618 0.0908
Schistosoma mansoni DNA polymerase IV / kappa 0.0026 0.0548 0.0598
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.234 0.3708
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0581 0.0535
Brugia malayi PHD-finger family protein 0.0028 0.0634 0.0588
Echinococcus multilocularis endoplasmin 0.0042 0.119 0.1839
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0548 0.0896
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0105 0.0075
Giardia lamblia DINP protein human, muc B family 0.0098 0.346 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0581 0.0422
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0105 0.0075
Loa Loa (eye worm) hypothetical protein 0.0119 0.4345 0.4317
Loa Loa (eye worm) hypothetical protein 0.0028 0.0634 0.0588
Schistosoma mansoni hypothetical protein 0.0033 0.0834 0.0947
Trypanosoma brucei DNA damage repair protein, putative 0.0026 0.0548 0.0896
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0104 0.0055
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.0206 0.0158
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0689 0.1181
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.3243 0.816
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.13 0.2017
Giardia lamblia Kinase, PLK 0.0092 0.3243 0.9322
Loa Loa (eye worm) hypothetical protein 0.006 0.1945 0.1905
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.7749 0.7738
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0025 0.0514 0.0826
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0098 0.346 1
Schistosoma mansoni hypothetical protein 0.005 0.1531 0.1797
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0264 0.0333
Echinococcus multilocularis p2X purinoceptor 4 0.0157 0.5888 0.9475
Leishmania major DNA polymerase eta, putative 0.0051 0.1565 0.3796
Loa Loa (eye worm) hypothetical protein 0.0018 0.0206 0.0158
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Schistosoma mansoni heat shock protein 0.0045 0.1303 0.1519
Leishmania major DNA polymerase eta, putative 0.011 0.3951 1
Trichomonas vaginalis set domain proteins, putative 0.023 0.8892 1
Schistosoma mansoni endoplasmin 0.0045 0.1303 0.1519
Toxoplasma gondii Hsp90 domain-containing protein 0.017 0.6404 1
Echinococcus granulosus lamin 0.0026 0.0547 0.0793
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.3243 0.321
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0025 0.0514 0.1063
Plasmodium falciparum ataxin-2 like protein, putative 0.0049 0.1482 0.2187
Brugia malayi intermediate filament protein 0.0026 0.0547 0.05
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Brugia malayi jmjC domain containing protein 0.0093 0.3271 0.3238
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.3271 0.522
Brugia malayi hypothetical protein 0.0119 0.4345 0.4317
Trichomonas vaginalis heat shock protein, putative 0.0038 0.1039 0.0646
Entamoeba histolytica hypothetical protein 0.007 0.234 0.6713
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0581 0.0535
Loa Loa (eye worm) hypothetical protein 0.0014 0.0059 0.001
Schistosoma mansoni kinase 0.0047 0.139 0.1626
Plasmodium falciparum endoplasmin, putative 0.0032 0.0801 0.1106
Onchocerca volvulus 0.0235 0.9078 1
Brugia malayi hypothetical protein 0.0049 0.1482 0.1441
Schistosoma mansoni hypothetical protein 0.0028 0.0634 0.0702
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0018 0.0206 0.0158
Loa Loa (eye worm) hypothetical protein 0.0018 0.0206 0.0158
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.1482 0.2784
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0264 0.0333
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3243 0.3272
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0581 0.0535
Giardia lamblia Grp94/Hsp90 0.0042 0.119 0.2899
Echinococcus granulosus p2X purinoceptor 4 0.0157 0.5888 0.9475
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0581 0.0535
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0264 0.0252
Schistosoma mansoni DNA helicase recq1 0.0019 0.0264 0.025
Echinococcus granulosus bloom syndrome protein 0.0047 0.1387 0.2158
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0039 0.1074 0.1539
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Trypanosoma brucei PAB1-binding protein , putative 0.0049 0.1482 0.2784
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.002 0.0283 0.0284
Mycobacterium ulcerans DNA polymerase IV 0.0137 0.5053 1
Schistosoma mansoni jumonji domain containing protein 0.0074 0.249 0.297
Echinococcus granulosus flap endonuclease 1 0.0025 0.0514 0.0739
Brugia malayi polk-prov protein 0.0078 0.2667 0.2631
Trypanosoma brucei DNA polymerase eta, putative 0.011 0.3951 0.7773
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0581 0.0535
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0581 0.0848
Loa Loa (eye worm) hypothetical protein 0.0068 0.2249 0.2211
Schistosoma mansoni heat shock protein 0.003 0.0689 0.077
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0547 0.05
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0264 0.0333
Schistosoma mansoni thyroid hormone receptor 0.015 0.5586 0.675
Mycobacterium tuberculosis Conserved hypothetical protein 0.0085 0.2935 0.8481
Schistosoma mansoni gabp alpha 0.0071 0.2364 0.2815
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0581 0.0848
Trypanosoma cruzi heat shock protein 90, putative 0.0045 0.1303 0.2421
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.1303 0.2421
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0689 0.0703
Echinococcus multilocularis expressed protein 0.0065 0.2135 0.3375
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0032 0.0767 0.1052
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.134 0.1005
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0661 0.0736
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0634 0.0934
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0521 0.0474
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.2364 0.3746
Loa Loa (eye worm) hypothetical protein 0.0258 1 1
Echinococcus granulosus heat shock protein 0.0045 0.1303 0.2022
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0634 0.0839
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0581 0.0535
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0283 0.0464
Brugia malayi heat shock protein 90 0.0045 0.1303 0.126
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0123 0.448 0.7185
Trichomonas vaginalis heat shock protein, putative 0.0045 0.1303 0.0961
Trichomonas vaginalis rotamase, putative 0.0065 0.2135 0.1952
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0018 0.0206 0.0158
Schistosoma mansoni tsg101-related 0.0046 0.1362 0.1591
Trypanosoma brucei chrX additional, unordered contigs 0.0026 0.0548 0.0896
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0661 0.0979
Plasmodium falciparum heat shock protein 90 0.0045 0.1303 0.1902
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0104 0.0055
Schistosoma mansoni P2X receptor subunit 0.0157 0.5888 0.7119
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Brugia malayi steroid hormone receptor 0.0027 0.0581 0.0535
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0581 0.0637
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Echinococcus granulosus peregrin 0.0028 0.0634 0.0934
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0038 0.1039 0.1592
Trichomonas vaginalis heat shock protein, putative 0.0042 0.119 0.0827
Trypanosoma brucei unspecified product 0.0058 0.1861 0.3549
Trypanosoma brucei DNA damage repair protein, putative 0.0026 0.0548 0.0896
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0068 0.2249 0.356
Plasmodium vivax heat shock protein, putative 0.017 0.6404 1
Entamoeba histolytica deoxycytidyl transferase, putative 0.0085 0.2935 0.8876
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0689 0.1024
Schistosoma mansoni DNA helicase recq5 0.0019 0.0264 0.025
Trichomonas vaginalis flap endonuclease-1, putative 0.0025 0.0514 0.0021
Brugia malayi Hsp90 protein 0.003 0.0689 0.0643
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0634 0.0934
Leishmania major hypothetical protein, conserved 0.0022 0.0362 0.0668
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.5053 1
Plasmodium vivax endoplasmin, putative 0.0045 0.1303 0.1902
Toxoplasma gondii heat shock protein HSP90 0.0045 0.1303 0.1902
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0581 0.0637
Trypanosoma brucei Heat shock protein 83, putative 0.0045 0.1303 0.2421
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0098 0.346 0.8724
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.3243 0.6343
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0037 0.0984 0.113
Echinococcus granulosus heat shock protein 90 0.0038 0.1039 0.1592
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.002 0.0283 0.0361
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0661 0.0979
Schistosoma mansoni hypothetical protein 0.0015 0.0104 0.0055
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0634 0.0839
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.1868 0.1828
Trypanosoma brucei unspecified product 0.0058 0.1861 0.3549
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0581 0.0848
Brugia malayi Fli-1 protein 0.0215 0.8247 0.8238
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.3243 0.3272
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.2135 0.1952
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0026 0.0548 0.0704
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0661 0.0979
Brugia malayi Bloom's syndrome protein homolog 0.0047 0.1387 0.1344
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.3243 1
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0634 0.0588
Schistosoma mansoni rotamase 0.0065 0.2135 0.2536
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0581 0.0535
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0581 0.0637
Brugia malayi hypothetical protein 0.0026 0.0521 0.0474
Trypanosoma cruzi Heat shock protein 83, putative 0.0045 0.1303 0.2421
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0537 0.0049
Echinococcus multilocularis lamin 0.0026 0.0547 0.0793
Schistosoma mansoni hypothetical protein 0.0123 0.448 0.5399
Loa Loa (eye worm) hypothetical protein 0.0019 0.0264 0.0216
Loa Loa (eye worm) hypothetical protein 0.0015 0.0104 0.0055
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0059 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0581 0.0535
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0085 0.2935 0.4674
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0521 0.075
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Schistosoma mansoni P2X receptor subunit 0.0157 0.5888 0.7119
Trypanosoma brucei unspecified product 0.0124 0.4527 0.8938
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0581 0.0637
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0064 0.2072 0.5738
Trypanosoma cruzi heat shock protein 90, putative 0.0038 0.1039 0.1887
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.1464 0.1422
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0375 0.0514
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0581 0.0535
Echinococcus multilocularis thyroid hormone receptor alpha 0.015 0.5586 0.8984
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.13 0.1515
Echinococcus multilocularis heat shock protein 0.0045 0.1303 0.2022
Giardia lamblia Heat shock protein HSP 90-alpha 0.0045 0.1303 0.325
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0581 0.0848
Brugia malayi Pre-SET motif family protein 0.0029 0.0661 0.0615
Brugia malayi isocitrate dehydrogenase 0.0015 0.0105 0.0056
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0137 0.5053 0.5428
Trypanosoma cruzi DNA polymerase eta, putative 0.0051 0.1565 0.2951
Loa Loa (eye worm) endoplasmin 0.0045 0.1303 0.126
Loa Loa (eye worm) pax transcription factor protein 2 0.0235 0.9078 0.9073
Schistosoma mansoni hypothetical protein 0.007 0.234 0.2786
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0018 0.0206 0.0158
Echinococcus granulosus jumonji domain containing protein 0.0039 0.1087 0.1672
Onchocerca volvulus Huntingtin homolog 0.0119 0.4345 0.4665
Brugia malayi jmjC domain containing protein 0.0034 0.0877 0.0833
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0877 0.133
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0689 0.0544
Loa Loa (eye worm) hypothetical protein 0.0027 0.0581 0.0535
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0123 0.448 0.7185
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0031 0.0752 0.1028
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.3243 0.3889
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0661 0.0736
Loa Loa (eye worm) hypothetical protein 0.0027 0.0581 0.0535
Brugia malayi nuclear hormone receptor 0.0027 0.0581 0.0535
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Schistosoma mansoni coup transcription factor 0.0027 0.0581 0.0637
Giardia lamblia PHD finger protein 15 0.0028 0.0634 0.1157
Loa Loa (eye worm) hypothetical protein 0.0026 0.0527 0.0481
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0068 0.2249 0.356
Brugia malayi hypothetical protein 0.0068 0.2249 0.2211
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0051 0.1565 0.2318
Plasmodium falciparum phd finger protein, putative 0.0028 0.0634 0.0839
Trypanosoma cruzi heat shock protein 85, putative 0.0038 0.1039 0.1887
Loa Loa (eye worm) hypothetical protein 0.0078 0.2667 0.2631
Leishmania major DNA damage repair protein, putative 0.0026 0.0548 0.1153
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Trypanosoma brucei DNA polymerase kappa, putative 0.0071 0.2386 0.4611
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0581 0.0535
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0264 0.0216
Schistosoma mansoni P2X receptor subunit 0.0157 0.5888 0.7119
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0264 0.0333
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0105 0.0075
Trypanosoma brucei DNA polymerase IV, putative 0.0124 0.4527 0.8938
Brugia malayi hypothetical protein 0.0018 0.0206 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0581 0.0535
Loa Loa (eye worm) RecQ helicase 0.0047 0.1387 0.1344
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0581 0.0848
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.2072 0.3977
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0105 0.0056
Loa Loa (eye worm) hypothetical protein 0.0049 0.1464 0.1422
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0581 0.0535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0581 0.0535
Giardia lamblia Heat shock protein HSP 90-alpha 0.0038 0.1039 0.2424
Loa Loa (eye worm) hypothetical protein 0.0049 0.1482 0.1441
Loa Loa (eye worm) hypothetical protein 0.0014 0.0059 0.001
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0104 0.0073
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0581 0.0848
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0581 0.0637
Trypanosoma brucei DNA polymerase kappa, putative 0.0137 0.5053 1
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0018 0.0206 0.018
Onchocerca volvulus 0.0026 0.0547 0.0384
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.13 0.1257
Loa Loa (eye worm) fli-1 protein 0.0215 0.8247 0.8238
Schistosoma mansoni intermediate filament proteins 0.0026 0.0547 0.0596
Loa Loa (eye worm) hypothetical protein 0.0119 0.4345 0.4317
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0104 0.0055
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0581 0.0848
Loa Loa (eye worm) hypothetical protein 0.0014 0.0059 0.001
Brugia malayi Pax transcription factor protein 2 0.0235 0.9078 0.9073
Trypanosoma brucei DNA polymerase IV, putative 0.0137 0.5053 1
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0375 0.0514
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0834 0.0789
Schistosoma mansoni thyroid hormone receptor 0.015 0.5586 0.675
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0581 0.0535
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0014 0.0053 0.5
Echinococcus granulosus GPCR family 2 0.0015 0.0104 0.0073
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0064 0.2072 0.3977
Loa Loa (eye worm) hypothetical protein 0.0049 0.1462 0.142
Trypanosoma cruzi PAB1-binding protein , putative 0.0049 0.1482 0.2784
Echinococcus multilocularis flap endonuclease 1 0.0025 0.0514 0.0739
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.002 0.0283 0.0361
Trichomonas vaginalis heat shock protein, putative 0.0042 0.119 0.0827
Brugia malayi nuclear receptor NHR-88 0.0027 0.0581 0.0535
Toxoplasma gondii LsmAD domain-containing protein 0.0049 0.1482 0.2187
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.024 0.0273
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.5053 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0581 0.0848
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0065 0.2135 0.2097
Trypanosoma cruzi DNA polymerase kappa, putative 0.0137 0.5053 1
Toxoplasma gondii heat shock protein 90, putative 0.0045 0.1303 0.1902
Loa Loa (eye worm) hypothetical protein 0.0018 0.0206 0.0158
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0042 0.119 0.5
Schistosoma mansoni lamin 0.0026 0.0547 0.0596
Schistosoma mansoni hypothetical protein 0.0015 0.0104 0.0055
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0085 0.2935 0.4674
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.0634 0.0839
Leishmania major DNA polymerase kappa, putative 0.0026 0.0548 0.1153
Echinococcus multilocularis p2X purinoceptor 4 0.0157 0.5888 0.9475
Echinococcus multilocularis heat shock protein 90 0.0045 0.1303 0.2022
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0581 0.0422
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0548 0.0896
Leishmania major heat shock protein 83-1 0.0045 0.1303 0.3114
Echinococcus granulosus heat shock protein 90 0.0045 0.1303 0.2022
Echinococcus granulosus expressed protein 0.0065 0.2135 0.3375
Plasmodium vivax heat shock protein 86, putative 0.0045 0.1303 0.1902
Brugia malayi ecdysteroid receptor 0.0027 0.0581 0.0535
Plasmodium vivax SET domain protein, putative 0.0029 0.0661 0.0883
Onchocerca volvulus Alhambra homolog 0.0028 0.0634 0.0482
Trichomonas vaginalis endoplasmin, putative 0.0032 0.0801 0.0364
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0521 0.075
Plasmodium vivax flap endonuclease 1, putative 0.0025 0.0514 0.0649
Echinococcus multilocularis peregrin 0.0028 0.0634 0.0934
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.3243 0.3424
Trypanosoma brucei DNA polymerase kappa, putative 0.0078 0.2667 0.5177
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0042 0.119 1
Toxoplasma gondii peptidylprolyl isomerase 0.0064 0.2072 0.3124
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0581 0.0848
Schistosoma mansoni jumonji/arid domain-containing protein 0.0034 0.0877 0.1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0581 0.0535
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.3271 0.522
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.1303 0.2421
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0085 0.2935 0.3512
Mycobacterium ulcerans DNA polymerase IV 0.0137 0.5053 1
Entamoeba histolytica hypothetical protein 0.007 0.234 0.6713
Echinococcus granulosus dna polymerase kappa 0.0137 0.5053 0.8117
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.2364 0.2326
Brugia malayi hypothetical protein 0.007 0.234 0.2303
Echinococcus multilocularis p2X purinoceptor 4 0.0157 0.5888 0.9475
Leishmania major heat shock protein, putative 0.003 0.0689 0.1519
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0581 0.0848
Loa Loa (eye worm) jmjC domain-containing protein 0.0034 0.0877 0.0833
Echinococcus multilocularis bloom syndrome protein 0.0047 0.1387 0.2158
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.1464 0.1422
Schistosoma mansoni heat shock protein 0.0045 0.1303 0.1519
Entamoeba histolytica hypothetical protein 0.007 0.234 0.6713
Loa Loa (eye worm) hypothetical protein 0.0027 0.0581 0.0535
Trichomonas vaginalis DNA helicase recq1, putative 0.0047 0.1387 0.1061
Schistosoma mansoni DNA polymerase eta 0.011 0.3951 0.4754
Giardia lamblia Flap structure-specific endonuclease 0.0025 0.0514 0.0781
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0025 0.0514 0.0826
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0046 0.1362 0.3151
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0496 0.0791
Schistosoma mansoni hypothetical protein 0.0015 0.0104 0.0055
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0661 0.0883
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0689 0.0928
Leishmania major hypothetical protein, conserved 0.0049 0.1482 0.3581
Echinococcus multilocularis GPCR, family 2 0.0015 0.0104 0.0073
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0025 0.0496 0.1017
Entamoeba histolytica Flap nuclease, putative 0.0025 0.0514 0.0064
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0042 0.119 0.2822
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.4238 0.421
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0689 0.1024
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0059 0.001
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0105 0.0075
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.13 0.2017
Schistosoma mansoni P2X receptor subunit 0.0157 0.5888 0.7119
Brugia malayi Flap endonuclease-1 0.0025 0.0514 0.0467
Plasmodium vivax DNA repair protein REV1, putative 0.0026 0.0548 0.0704
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0581 0.0535
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0264 0.0252
Schistosoma mansoni transcription factor LCR-F1 0.007 0.234 0.2786
Loa Loa (eye worm) hypothetical protein 0.0018 0.0206 0.0158
Trichomonas vaginalis hypothetical protein 0.0033 0.0826 0.0393
Trypanosoma brucei heat shock protein, putative 0.0045 0.1303 0.2421
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0025 0.0514 0.0649
Brugia malayi hypothetical protein 0.0018 0.0206 0.0158
Loa Loa (eye worm) flap endonuclease-1 0.0025 0.0514 0.0467
Entamoeba histolytica hypothetical protein 0.007 0.234 0.6713
Brugia malayi ImpB/MucB/SamB family protein 0.0085 0.2935 0.29
Schistosoma mansoni hypothetical protein 0.0165 0.6211 0.7514
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0581 0.0848
Mycobacterium ulcerans heat shock protein 90 0.0042 0.119 0.1425

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.13 Biological activity of the compound was measured against Angiotensin I converting enzyme ChEMBL. 7629809
Log 1/IC50 (binding) = 2.13 Biological activity of the compound was measured against Angiotensin I converting enzyme ChEMBL. 7629809

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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