Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0317 | 0.0793 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0535 | 0.0535 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0317 | 0.0317 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | oxidoreductase | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.293 | 0.293 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0047 | 0.0535 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0317 | 0.0793 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0317 | 0.0317 |
Onchocerca volvulus | 0.0047 | 0.0535 | 0.0226 | |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0047 | 0.0535 | 0.0535 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0317 | 0.0793 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0317 | 0.0317 |
Loa Loa (eye worm) | hexokinase | 0.0337 | 0.6137 | 0.6137 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0047 | 0.0535 | 0.0535 |
Echinococcus multilocularis | aldo keto reductase | 0.0047 | 0.0535 | 0.0535 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0047 | 0.0535 | 0.0535 |
Brugia malayi | NADH-dependent xylose reductase | 0.0047 | 0.0535 | 0.0535 |
Entamoeba histolytica | aldose reductase, putative | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 0.6704 | 0.6704 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0317 | 0.0317 |
Echinococcus granulosus | aldo keto reductase | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0317 | 0.5918 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0317 | 0.5918 |
Brugia malayi | Hexokinase family protein | 0.0337 | 0.6137 | 0.6137 |
Loa Loa (eye worm) | oxidoreductase | 0.0047 | 0.0535 | 0.0535 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0047 | 0.0535 | 0.0535 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0317 | 0.5918 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0317 | 0.0317 |
Loa Loa (eye worm) | oxidoreductase | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0049 | 0.0572 | 0.0572 |
Toxoplasma gondii | aldose reductase, putative | 0.0047 | 0.0535 | 0.0226 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0317 | 0.5918 |
Echinococcus multilocularis | aldo keto reductase | 0.0047 | 0.0535 | 0.0535 |
Brugia malayi | Hexokinase family protein | 0.0166 | 0.2842 | 0.2842 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0047 | 0.0535 | 1 |
Onchocerca volvulus | 0.0047 | 0.0535 | 0.0226 | |
Leishmania major | aldo-keto reductase-like protein | 0.0047 | 0.0535 | 0.0535 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Schistosoma mansoni | aldo-keto reductase | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0047 | 0.0535 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0317 | 0.0793 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0317 | 0.0317 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0047 | 0.0535 | 0.0535 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Echinococcus granulosus | hypothetical protein | 0.0047 | 0.0535 | 0.0535 |
Toxoplasma gondii | aldo-keto reductase | 0.0047 | 0.0535 | 0.0226 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0047 | 0.0535 | 0.0535 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0317 | 0.0317 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0317 | 0.0793 |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.0535 | 1 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0047 | 0.0535 | 0.0226 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0317 | 0.0317 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0317 | 0.5918 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0317 | 0.5918 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0317 | 0.0317 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0047 | 0.0535 | 0.0226 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0047 | 0.0535 | 0.0535 |
Brugia malayi | Cytochrome P450 family protein | 0.0049 | 0.0572 | 0.0572 |
Schistosoma mansoni | pol-related | 0.0047 | 0.0535 | 0.0535 |
Onchocerca volvulus | 0.0047 | 0.0535 | 0.0226 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Entamoeba histolytica | aldose reductase, putative | 0.0047 | 0.0535 | 0.0535 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Onchocerca volvulus | Hexokinase homolog | 0.0337 | 0.6137 | 0.6011 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0047 | 0.0535 | 0.0226 |
Echinococcus granulosus | aldo keto reductase | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0047 | 0.0535 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Leishmania major | prostaglandin f synthase, putative | 0.0047 | 0.0535 | 0.0535 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Echinococcus multilocularis | aldo keto reductase | 0.0047 | 0.0535 | 0.0535 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0317 | 0.0317 |
Echinococcus granulosus | aldo keto reductase | 0.0047 | 0.0535 | 0.0535 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0317 | 0.0793 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0047 | 0.0535 | 0.0535 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0317 | 0.5918 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0226 | 0.3995 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0317 | 0.0317 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0047 | 0.0535 | 0.0535 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Entamoeba histolytica | aldose reductase, putative | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0317 | 0.0317 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0047 | 0.0535 | 1 |
Onchocerca volvulus | 0.0047 | 0.0535 | 0.0226 | |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.293 | 0.293 |
Trypanosoma cruzi | aldo-keto reductase | 0.0047 | 0.0535 | 0.0535 |
Giardia lamblia | Aldose reductase | 0.0047 | 0.0535 | 1 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0317 | 0.0793 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0317 | 0.0317 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0047 | 0.0535 | 0.0535 |
Onchocerca volvulus | 0.0047 | 0.0535 | 0.0226 | |
Plasmodium vivax | aldehyde reductase, putative | 0.0047 | 0.0535 | 0.0226 |
Schistosoma mansoni | potassium channel beta | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0317 | 0.0317 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0047 | 0.0535 | 0.134 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0317 | 0.0793 |
Loa Loa (eye worm) | hexokinase | 0.0166 | 0.2842 | 0.2842 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0317 | 0.0793 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0317 | 0.5918 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0047 | 0.0535 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0317 | 0.0317 |
Mycobacterium leprae | Possible oxidoreductase | 0.0047 | 0.0535 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0047 | 0.0535 | 1 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0047 | 0.0535 | 0.0535 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0047 | 0.0535 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0317 | 0.0317 |
Onchocerca volvulus | 0.0337 | 0.6137 | 0.6011 | |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0317 | 0.5918 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0317 | 0.5918 |
Brugia malayi | hexokinase type II | 0.0171 | 0.293 | 0.293 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0535 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0317 | 0.5918 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0047 | 0.0535 | 0.0535 |
Onchocerca volvulus | 0.0047 | 0.0535 | 0.0226 | |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0317 | 0.0317 |
Giardia lamblia | Aldose reductase | 0.0047 | 0.0535 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Mycobacterium ulcerans | oxidoreductase | 0.0047 | 0.0535 | 1 |
Onchocerca volvulus | 0.0047 | 0.0535 | 0.0226 | |
Mycobacterium tuberculosis | Conserved protein | 0.0047 | 0.0535 | 0.134 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0317 | 0.0317 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0317 | 0.0317 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Schistosoma mansoni | aldo-keto reductase | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | oxidoreductase | 0.0047 | 0.0535 | 0.0535 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0317 | 0.0793 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0047 | 0.0535 | 0.0535 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0047 | 0.0535 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0047 | 0.0535 | 0.0535 |
Trypanosoma brucei | prostaglandin f synthase | 0.0047 | 0.0535 | 0.0535 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0317 | 0.0317 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0047 | 0.0535 | 0.0535 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.