Detailed information for compound 150819

Basic information

Technical information
  • TDR Targets ID: 150819
  • Name: 3-[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)pr opylcarbamoyl]benzenesulfonyl fluoride
  • MW: 479.525 | Formula: C21H26FN5O5S
  • H donors: 2 H acceptors: 6 LogP: 2.81 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCn1c2[nH]c(nc2c(=O)n(c1=O)CCC)CCCNC(=O)c1cccc(c1)S(=O)(=O)F
  • InChi: 1S/C21H26FN5O5S/c1-3-11-26-18-17(20(29)27(12-4-2)21(26)30)24-16(25-18)9-6-10-23-19(28)14-7-5-8-15(13-14)33(22,31)32/h5,7-8,13H,3-4,6,9-12H2,1-2H3,(H,23,28)(H,24,25)
  • InChiKey: NDOXGECHRSCPAH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[[3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)propylamino]-oxomethyl]benzenesulfonyl fluoride
  • 3-[3-(2,6-diketo-1,3-dipropyl-7H-purin-8-yl)propylcarbamoyl]benzenesulfonyl fluoride

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens adenosine A1 receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi hypothetical protein adenosine A1 receptor 326 aa 305 aa 21.0 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Conserved protein 0.0071 0.1138 0.1122
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.044 0.1522
Loa Loa (eye worm) hypothetical protein 0.0101 0.1821 0.2682
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0073 0.1179 0.1182
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0886 0.3132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Brugia malayi Serotonin receptor 0.0082 0.1385 0.207
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.1138 0.4046
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Brugia malayi 6-phosphofructokinase 0.0108 0.1985 0.2972
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Echinococcus multilocularis dna polymerase kappa 0.006 0.0874 0.0877
Echinococcus granulosus neuropeptide receptor A26 0.0082 0.1385 0.139
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0025 0.0061 0.0152
Loa Loa (eye worm) hypothetical protein 0.0046 0.0552 0.0803
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Onchocerca volvulus 0.0055 0.0772 0.1543
Mycobacterium ulcerans sugar transporter 0.0029 0.0168 0.0537
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0082 0.1385 0.2037
Echinococcus multilocularis neuropeptide receptor A26 0.0082 0.1385 0.139
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0319 0.0319
Brugia malayi major facilitator superfamily protein 0.0029 0.0168 0.0238
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.031 0.6658 0.9841
Loa Loa (eye worm) hypothetical protein 0.0028 0.0147 0.0204
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0205 0.4229 0.4242
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0031 0.0199 0.0199
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0168 0.057
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0057 0.0799 0.0802
Schistosoma mansoni multidrug resistance protein 0.0034 0.0276 0.0268
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.044 0.1551
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0205 0.4229 0.4242
Echinococcus granulosus voltage dependent calcium channel 0.0095 0.1686 0.1691
Echinococcus multilocularis solute carrier family 22 0.0029 0.0168 0.0168
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0183 0.0183
Brugia malayi jmjC domain containing protein 0.006 0.0874 0.13
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0121 0.0245
Loa Loa (eye worm) beta-lactamase 0.0071 0.1138 0.1671
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1138 0.2305
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0019 0.001
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1138 0.2305
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.1007 0.3593
Entamoeba histolytica hypothetical protein 0.0036 0.0319 0.0561
Echinococcus granulosus potassium voltage gated channel protein 0.0022 0.0009 0.0009
Echinococcus multilocularis allatostatin A receptor 0.0082 0.1385 0.139
Onchocerca volvulus 0.003 0.0183 0.0351
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0082 0.1385 0.139
Entamoeba histolytica hypothetical protein 0.0036 0.0319 0.0561
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Brugia malayi sulfakinin receptor protein 0.0082 0.1385 0.207
Schistosoma mansoni sugar transporter 0.0029 0.0168 0.0159
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0168 0.0168
Brugia malayi multidrug resistance protein 3 0.0031 0.0219 0.0315
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0219 0.0443
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0416 0.1464
Plasmodium vivax multidrug resistance protein 1, putative 0.0031 0.0219 0.0527
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0121 0.0121
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0082 0.1395 0.2085
Schistosoma mansoni hypothetical protein 0.0067 0.105 0.1045
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0168 0.0238
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Echinococcus multilocularis g protein coupled receptor 0.0082 0.1385 0.139
Leishmania major hypothetical protein, conserved 0.0034 0.0276 0.096
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0886 0.3156
Giardia lamblia DINP protein human, muc B family 0.004 0.0416 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0265 0.092
Plasmodium vivax glutathione reductase, putative 0.0047 0.0578 0.1811
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0205 0.4229 0.4242
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0082 0.1385 0.139
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0082 0.1385 0.139
Echinococcus granulosus solute carrier family 22 0.0029 0.0168 0.0168
Echinococcus multilocularis serotonin receptor 0.0082 0.1385 0.139
Brugia malayi SPARC precursor 0.0038 0.0367 0.0537
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0025 0.0061 0.0042
Echinococcus granulosus transient receptor potential cation channel 0.0385 0.8382 0.8407
Brugia malayi ABC transporter family protein 0.0031 0.0219 0.0315
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0578 0.1811
Onchocerca volvulus 0.0029 0.0168 0.032
Echinococcus multilocularis transient receptor potential cation channel 0.0022 0.0009 0.0009
Onchocerca volvulus 0.0023 0.0019 0.0019
Toxoplasma gondii sugar transporter ST2 0.0029 0.0168 0.0553
Loa Loa (eye worm) hypothetical protein 0.0031 0.0219 0.031
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1985 0.4019
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0886 0.3132
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0214 0.0308
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0082 0.1385 0.207
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0183 0.0257
Toxoplasma gondii sugar transporter ST3 0.0029 0.0168 0.0553
Echinococcus granulosus hypothetical protein 0.0082 0.1385 0.139
Brugia malayi polk-prov protein 0.0037 0.0343 0.0501
Echinococcus multilocularis acetylcholinesterase 0.0135 0.2601 0.2609
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0262 0.0374
Schistosoma mansoni amine GPCR 0.0082 0.1385 0.1381
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0367 0.0529
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0183 0.0261
Brugia malayi Carboxylesterase family protein 0.0023 0.0019 0.0014
Echinococcus granulosus voltage gated hydrogen channel 1 0.0022 0.0009 0.0009
Entamoeba histolytica P-glycoprotein 5, putative 0.0031 0.0219 0.0192
Echinococcus granulosus BC026374 protein S09 family 0.0023 0.0019 0.0019
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0066 0.1018 0.1516
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0025 0.0061 0.0152
Loa Loa (eye worm) TYRA-2 protein 0.0082 0.1385 0.2037
Schistosoma mansoni neuropeptide receptor 0.0082 0.1385 0.1381
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.1007 0.3593
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0183 0.0183
Echinococcus multilocularis voltage gated potassium channel 0.0031 0.0199 0.0199
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0025 0.0061 0.0152
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0061 0.0186
Echinococcus granulosus transient receptor potential cation channel 0.0022 0.0009 0.0009
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0219 0.0443
Trypanosoma brucei trypanothione reductase 0.0047 0.0578 0.2047
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0031 0.0219 0.0733
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1985 0.4019
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0029 0.0168 0.0168
Brugia malayi cytochrome P450 0.0025 0.0061 0.0078
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0772 0.0774
Loa Loa (eye worm) hypothetical protein 0.0055 0.0772 0.1129
Entamoeba histolytica P-glycoprotein-2 0.0031 0.0219 0.0192
Echinococcus multilocularis potassium voltage gated channel protein 0.0028 0.0147 0.0147
Echinococcus granulosus neuropeptide FF receptor 2 0.0082 0.1385 0.139
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0367 0.0537
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0205 0.4229 0.4236
Brugia malayi Dopamine receptor protein 2 0.0082 0.1385 0.207
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0082 0.1385 0.139
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0183 0.0174
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0276 0.096
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0219 0.0443
Plasmodium vivax SET domain protein, putative 0.003 0.0194 0.0438
Echinococcus granulosus neuroligin 0.0023 0.0019 0.0019
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.2242 0.8004
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.1007 0.101
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0025 0.0061 0.0042
Echinococcus granulosus lysine specific demethylase 5A 0.006 0.0874 0.0877
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0265 0.0246
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1138 0.1133
Leishmania major trypanothione reductase 0.0047 0.0578 0.2047
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.2242 0.2227
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0082 0.1385 0.1381
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0874 0.3091
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.044 0.0441
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Brugia malayi nuclear hormone receptor 0.003 0.0183 0.0261
Echinococcus granulosus dro:myosuppressin receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus granulosus voltage gated potassium channel 0.0031 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0014
Mycobacterium ulcerans lysophospholipase 0.0143 0.2786 1
Echinococcus granulosus voltage dependent calcium channel 0.0205 0.4229 0.4242
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.1007 0.3593
Brugia malayi Pre-SET motif family protein 0.003 0.0194 0.0278
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0025 0.0061 0.0152
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) hypothetical protein 0.0038 0.0367 0.0529
Echinococcus multilocularis transient receptor potential gamma protein 0.0022 0.0009 0.0009
Echinococcus granulosus para nitrobenzyl esterase 0.0023 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus multilocularis potassium voltage gated channel protein 0.0105 0.1911 0.1916
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0121 0.0112
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0168 0.0168
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0025 0.0061 0.0042
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0183 0.0183
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) neuropeptide F receptor 0.0082 0.1385 0.2037
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0082 0.1385 0.139
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.1138 0.2305
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0886 0.088
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0082 0.1385 0.139
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.044 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1138 0.2305
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) cytochrome P450 0.0025 0.0061 0.0077
Onchocerca volvulus 0.0055 0.0772 0.1543
Giardia lamblia Sugar-proton symporter 0.0029 0.0168 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Brugia malayi RE15519p 0.0082 0.1385 0.207
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Loa Loa (eye worm) hypothetical protein 0.0067 0.105 0.1541
Brugia malayi Tachykinin-like peptides receptor 99D 0.0082 0.1385 0.207
Echinococcus multilocularis short transient receptor potential channel 6 0.0023 0.0022 0.0022
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0082 0.1385 0.1381
Brugia malayi Dopamine receptor 0.0082 0.1385 0.207
Schistosoma mansoni thyroid hormone receptor 0.0155 0.3068 0.3071
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0219 0.022
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0073 0.1179 0.1182
Trypanosoma brucei unspecified product 0.0023 0.0026 0.0058
Echinococcus granulosus potassium large conductance calcium activated 0.0022 0.0009 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0177 0.0603
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Schistosoma mansoni biogenic amine receptor 0.0082 0.1385 0.1381
Brugia malayi beta-lactamase 0.0071 0.1138 0.1698
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.1138 0.4046
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0214 0.0215
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Brugia malayi Cytochrome P450 family protein 0.0025 0.0061 0.0078
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0168 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0183 0.0261
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0219 0.0443
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0183 0.0183
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Echinococcus granulosus multidrug resistance protein 1 0.0031 0.0219 0.022
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0025 0.0061 0.0152
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0219 0.0443
Trichomonas vaginalis abcb9, putative 0.0031 0.0219 0.0443
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0343 0.12
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0168 0.057
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0025 0.0061 0.0042
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.044 0.1011
Schistosoma mansoni biogenic amine receptor 0.0082 0.1385 0.1381
Echinococcus granulosus hypothetical protein 0.0022 0.0009 0.0009
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0065 0.099 0.0993
Echinococcus multilocularis transient receptor potential cation channel 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus multilocularis fmrfamide receptor 0.0082 0.1385 0.139
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0168 0.0168
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.1955 0.1953
Echinococcus granulosus solute carrier family 22 0.0029 0.0168 0.0168
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0183 0.0174
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.0367 0.0529
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0025 0.0061 0.0152
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0832 0.0826
Leishmania major hypothetical protein, conserved 0.0029 0.0168 0.057
Echinococcus granulosus neuropeptides capa receptor 0.0082 0.1385 0.139
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0029 0.0157 0.0148
Loa Loa (eye worm) hypothetical protein 0.0031 0.0219 0.031
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0025 0.0061 0.0186
Plasmodium vivax hypothetical protein, conserved 0.0071 0.1138 0.3816
Onchocerca volvulus 0.0082 0.1385 0.2784
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.2867 0.5804
Brugia malayi olfactory channel protein osm-9 0.0023 0.0022 0.0019
Schistosoma mansoni hypothetical protein 0.0082 0.1385 0.1381
Onchocerca volvulus 0.0082 0.1385 0.2784
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0194 0.0186
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0147 0.0138
Loa Loa (eye worm) glutathione reductase 0.0047 0.0578 0.0841
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.1385 0.1381
Schistosoma mansoni hypothetical protein 0.0454 0.997 1
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0772 0.1543
Echinococcus multilocularis two pore calcium channel protein 2 0.0022 0.0009 0.0009
Trichomonas vaginalis esterase, putative 0.0071 0.1138 0.2305
Brugia malayi GnHR receptor homolog 0.0082 0.1385 0.207
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0025 0.0061 0.0042
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0082 0.1385 0.139
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0772 0.2747
Brugia malayi hypothetical protein 0.0036 0.0319 0.0465
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0284 0.0574
Echinococcus granulosus shaker cognate 0.0028 0.0147 0.0147
Echinococcus multilocularis sodium leak channel non selective protein 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0194 0.0274
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.1966 0.1951
Toxoplasma gondii thioredoxin reductase 0.0047 0.0578 0.1989
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0065 0.099 0.1452
Schistosoma mansoni voltage-gated potassium channel 0.0027 0.0121 0.0112
Trichomonas vaginalis abcb9, putative 0.0031 0.0219 0.0443
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) calcium channel 0.0205 0.4229 0.6246
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0772 0.1543
Echinococcus multilocularis neuropeptides capa receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1985 0.2925
Echinococcus multilocularis fmrfamide receptor 0.0082 0.1385 0.139
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1985 0.4019
Echinococcus multilocularis G-protein coupled receptor, putative 0.0082 0.1385 0.139
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0092 0.1618 0.5794
Echinococcus granulosus sex peptide receptor 0.0082 0.1385 0.139
Onchocerca volvulus 0.0082 0.1385 0.2784
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0183 0.0183
Brugia malayi AKH receptor 0.0082 0.1385 0.207
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0338
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0183 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0014
Echinococcus multilocularis g-protein coupled receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0027 0.0121 0.0165
Plasmodium vivax sugar transporter, putative 0.0029 0.0168 0.0343
Echinococcus granulosus hyperpolarization activated cyclic 0.0027 0.0121 0.0121
Loa Loa (eye worm) hypothetical protein 0.0031 0.0214 0.0303
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0168 0.0234
Onchocerca volvulus 0.0082 0.1385 0.2784
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0262 0.0374
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Trypanosoma brucei glucose transporter 2A 0.0029 0.0168 0.057
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0183 0.0261
Echinococcus granulosus carboxylesterase 5A 0.0135 0.2601 0.2609
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0025 0.0061 0.0152
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0874 0.3115
Echinococcus multilocularis voltage dependent calcium channel 0.0205 0.4229 0.4242
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0143 0.2786 1
Brugia malayi CXXC zinc finger family protein 0.0032 0.023 0.0331
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0886 0.0888
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0214 0.0308
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0108 0.1985 0.197
Echinococcus multilocularis two pore calcium channel protein 1 0.0022 0.0009 0.0009
Schistosoma mansoni coup transcription factor 0.003 0.0183 0.0174
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0832 0.0835
Echinococcus granulosus glycine receptor subunit alpha 1 0.0073 0.1179 0.1182
Echinococcus granulosus 7tm_1 domain containing protein 0.0082 0.1385 0.139
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0168 0.0168
Echinococcus granulosus ryanodine receptor 44f 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0168 0.0149
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0031 0.0219 0.0443
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0025 0.0061 0.0186
Loa Loa (eye worm) hypothetical protein 0.0025 0.0072 0.0092
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0265 0.0384
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0101 0.1817 0.1822
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0073 0.1179 0.1731
Toxoplasma gondii cytochrome p450 superfamily protein 0.0025 0.0061 0.0181
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.044 0.1551
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0416 0.0398
Schistosoma mansoni adenoreceptor 0.0082 0.1385 0.1381
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Brugia malayi Pre-SET motif family protein 0.0207 0.428 0.6424
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Schistosoma mansoni hypothetical protein 0.0168 0.3378 0.3382
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0219 0.0443
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.1385 0.139
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0183 0.0183
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.1966 0.6992
Onchocerca volvulus 0.0032 0.023 0.0445
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Plasmodium falciparum esterase, putative 0.0143 0.2786 0.9711
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.1385 0.139
Echinococcus granulosus glycine receptor subunit beta 0.0073 0.1179 0.1182
Loa Loa (eye worm) sugar transporter 0.0029 0.0168 0.0234
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0031 0.0219 0.0443
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0886 0.3132
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0037 0.0341 0.1027
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1985 0.6736
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0183 0.0183
Echinococcus granulosus neuropeptide receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) hypothetical protein 0.0033 0.0265 0.0378
Echinococcus granulosus orexin receptor type 2 0.0082 0.1385 0.139
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0265 0.0362
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Toxoplasma gondii transporter, cation channel family protein 0.0095 0.1686 0.5867
Schistosoma mansoni gliotactin 0.0023 0.0019 0.001
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1985 0.1984
Schistosoma mansoni hypothetical protein 0.0125 0.2379 0.2379
Brugia malayi hypothetical protein 0.0029 0.0168 0.0238
Echinococcus multilocularis sodium channel protein 0.0122 0.2321 0.2328
Echinococcus granulosus solute carrier family 22 0.0029 0.0168 0.0168
Toxoplasma gondii sugar transporter ST1 0.0029 0.0168 0.0553
Echinococcus granulosus acetylcholinesterase 0.0135 0.2601 0.2609
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0082 0.1385 0.207
Mycobacterium ulcerans hypothetical protein 0.0071 0.1138 0.4046
Loa Loa (eye worm) hypothetical protein 0.0135 0.2601 0.3837
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0168 0.0343
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0886 0.0888
Toxoplasma gondii facilitative glucose transporter GT1 0.0029 0.0168 0.0553
Leishmania major DNA polymerase kappa, putative 0.004 0.0416 0.1464
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0082 0.1385 0.2037
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0772 0.0774
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Onchocerca volvulus 0.0071 0.1138 0.2284
Onchocerca volvulus 0.0082 0.1385 0.2784
Echinococcus multilocularis solute carrier family 22 0.0029 0.0168 0.0168
Onchocerca volvulus 0.0029 0.0168 0.032
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0082 0.1385 0.1381
Brugia malayi Cyclic-nucleotide gated cation channel 0.0027 0.0121 0.0168
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0183 0.0257
Echinococcus multilocularis potassium voltage gated channel protein 0.0022 0.0009 0.0009
Echinococcus multilocularis voltage dependent calcium channel 0.0205 0.4229 0.4242
Echinococcus multilocularis multidrug resistance protein 1 0.0031 0.0219 0.022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0183 0.0261
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.1385 0.1381
Echinococcus granulosus TRP transient receptor potential channel 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Onchocerca volvulus 0.0029 0.0168 0.032
Brugia malayi hypothetical protein 0.0029 0.0168 0.0238
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0027 0.0121 0.0245
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0025 0.0061 0.0186
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0183 0.0257
Echinococcus granulosus solute carrier family 22 0.0029 0.0168 0.0168
Trypanosoma cruzi membrane transporter protein, putative 0.0034 0.0276 0.096
Echinococcus granulosus follistatin 0.0038 0.0367 0.0368
Echinococcus granulosus dna polymerase kappa 0.006 0.0874 0.0877
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Brugia malayi jmjC domain containing protein 0.0058 0.0832 0.1237
Onchocerca volvulus 0.0029 0.0168 0.032
Onchocerca volvulus Putative transporter 0.0029 0.0168 0.032
Schistosoma mansoni organic anion transporter 0.0055 0.0772 0.0766
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.1138 0.4066
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.1385 0.139
Entamoeba histolytica hypothetical protein 0.0036 0.0319 0.0561
Echinococcus granulosus biogenic amine 5HT receptor 0.0082 0.1385 0.139
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0183 0.0183
Leishmania major hypothetical protein, conserved 0.0025 0.0072 0.0224
Echinococcus granulosus G protein coupled receptor 139 0.0082 0.1385 0.139
Echinococcus multilocularis shaker cognate 0.0028 0.0147 0.0147
Onchocerca volvulus 0.0071 0.1138 0.2284
Toxoplasma gondii protease inhibitor PI2 0.0038 0.0367 0.125
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Echinococcus granulosus multidrug resistance protein 1 0.0031 0.0219 0.022
Loa Loa (eye worm) GABA receptor subunit 0.0066 0.1018 0.1492
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Plasmodium falciparum lysophospholipase, putative 0.0143 0.2786 0.9711
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0146 0.2867 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0167 0.0341
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.037 0.0371
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0082 0.1385 0.139
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0205 0.4229 0.4242
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0177 0.0603
Echinococcus multilocularis serotonin receptor 0.0082 0.1385 0.139
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0153 0.0153
Schistosoma mansoni opsin-like receptor 0.0082 0.1385 0.1381
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0028 0.0147 0.0207
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0168 0.0339
Onchocerca volvulus 0.0082 0.1385 0.2784
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0578 0.056
Schistosoma mansoni amine GPCR 0.0082 0.1385 0.1381
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0082 0.1385 0.207
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0578 0.0579
Echinococcus multilocularis geminin 0.0168 0.3378 0.3388
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0025 0.0061 0.0152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0168 0.0168
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0338
Schistosoma mansoni hypothetical protein 0.0082 0.1385 0.1381
Echinococcus multilocularis potassium large conductance calcium activated 0.0022 0.0009 0.0009
Echinococcus granulosus cpg binding protein 0.0034 0.0271 0.0272
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.1385 0.139
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0367 0.125
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Echinococcus multilocularis g protein coupled receptor 0.0082 0.1385 0.139
Schistosoma mansoni neuropeptide receptor 0.0082 0.1385 0.1381
Echinococcus multilocularis transient receptor potential cation channel 0.0386 0.8395 0.842
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0183 0.0261
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0219 0.022
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.1007 0.1001
Onchocerca volvulus 0.0029 0.0168 0.032
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0025 0.0061 0.0042
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.1966 0.1951
Schistosoma mansoni neuroligin 3 (S09 family) 0.0023 0.0019 0.001
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0025 0.0061 0.0042
Echinococcus multilocularis cpg binding protein 0.0034 0.0271 0.0272
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0219 0.022
Echinococcus multilocularis neuropeptide Y receptor 0.0082 0.1385 0.139
Schistosoma mansoni biogenic amine receptor 0.0082 0.1385 0.1381
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0183 0.0257
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0082 0.1385 0.2037
Echinococcus multilocularis GPCR, family 2 0.0031 0.0214 0.0215
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0168 0.057
Schistosoma mansoni glucose transporter 0.0029 0.0168 0.0159
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0031 0.0219 0.0755
Schistosoma mansoni biogenic amine (5HT) receptor 0.0082 0.1385 0.1381
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0167 0.0338
Onchocerca volvulus 0.0082 0.1385 0.2784
Brugia malayi Calcitonin receptor-like protein seb-1 0.0099 0.1771 0.2649
Trichomonas vaginalis abcb9, putative 0.0031 0.0219 0.0443
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1985 0.6736
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0168 0.057
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.044 0.1507
Leishmania major glucose transporter, lmgt3 0.0029 0.0168 0.057
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.2242 0.2227
Onchocerca volvulus 0.0082 0.1385 0.2784
Onchocerca volvulus 0.0023 0.0019 0.0019
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0028 0.0147 0.0147
Schistosoma mansoni 6-phosphofructokinase 0.0108 0.1985 0.1984
Loa Loa (eye worm) melatonin receptor type 1A 0.0082 0.1385 0.2037
Entamoeba histolytica P-glycoprotein-1 0.0031 0.0219 0.0192
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0319 0.0319
Onchocerca volvulus 0.0029 0.0168 0.032
Onchocerca volvulus 0.0023 0.0019 0.0019
Trypanosoma brucei sugar transporter, putative 0.0029 0.0168 0.057
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0073 0.1179 0.1182
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0183 0.0174
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0027 0.0121 0.0121
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0874 0.0868
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0107 0.1955 0.196
Brugia malayi hypothetical protein 0.0055 0.0772 0.1147
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus granulosus expressed protein 0.0414 0.9055 0.9081
Echinococcus multilocularis neuropeptide s receptor 0.0082 0.1385 0.139
Mycobacterium tuberculosis Possible lysophospholipase 0.0143 0.2786 0.2772
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Echinococcus multilocularis dnaJ subfamily B 0.0454 0.997 1
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Loa Loa (eye worm) hypothetical protein 0.0099 0.1771 0.2607
Echinococcus granulosus transient receptor potential cation channel 0.0022 0.0009 0.0009
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0121 0.0112
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.1138 0.1142
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0276 0.096
Schistosoma mansoni organic anion transporter 0.0055 0.0772 0.0766
Schistosoma mansoni inositol monophosphatase 0.0041 0.044 0.0432
Schistosoma mansoni follistatin 0.0038 0.0367 0.0359
Entamoeba histolytica P-glyco protein 6, putative 0.0031 0.0219 0.0192
Echinococcus multilocularis neuropeptide FF receptor 2 0.0082 0.1385 0.139
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0772 0.1129
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0025 0.0061 0.0152
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0416 0.1464
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0168 0.0339
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0029 0.0168 0.0168
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.1385 0.1381
Leishmania major glucose transporter, lmgt2 0.0029 0.0168 0.057
Loa Loa (eye worm) hypothetical protein 0.0055 0.0772 0.1129
Trichomonas vaginalis taga, putative 0.0031 0.0219 0.0443
Brugia malayi hypothetical protein 0.0101 0.1821 0.2725
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0025 0.0061 0.0042
Plasmodium falciparum multidrug resistance protein 1 0.0031 0.0219 0.0527
Echinococcus granulosus fmrfamide receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.1138 0.1671
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0025 0.0061 0.0042
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0061 0.0077
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.1385 0.139
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0121 0.0112
Entamoeba histolytica hypothetical protein 0.0036 0.0319 0.0561
Schistosoma mansoni smdr2 0.0031 0.0219 0.021
Schistosoma mansoni lipoxygenase 0.0082 0.1384 0.138
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0168 0.0168
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0183 0.0351
Onchocerca volvulus 0.0082 0.1385 0.2784
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0025 0.0061 0.0152
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Loa Loa (eye worm) hypothetical protein 0.0031 0.0199 0.028
Onchocerca volvulus 0.0029 0.0168 0.032
Schistosoma mansoni nuclear hormone receptor 0.003 0.0183 0.0174
Brugia malayi ORL1-like opioid receptor 0.0082 0.1385 0.207
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0183 0.0183
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) voltage-dependent calcium channel 0.0095 0.1686 0.2481
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.1966 0.1951
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0874 0.3115
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0025 0.0061 0.0042
Onchocerca volvulus 0.0029 0.0168 0.032
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Leishmania major glucose transporter/membrane transporter D2, putative 0.0029 0.0168 0.057
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Onchocerca volvulus 0.0031 0.0219 0.0424
Trypanosoma brucei MATE efflux family protein, putative 0.0034 0.0276 0.096
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0147 0.0138
Mycobacterium tuberculosis Conserved protein 0.0071 0.1138 0.1122
Echinococcus multilocularis sex peptide receptor 0.0082 0.1385 0.139
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.2197 0.2204
Trypanosoma cruzi hexose transporter 0.0029 0.0168 0.057
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0025 0.0061 0.0152
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0031 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0135 0.2601 0.3837
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0025 0.0061 0.0152
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0167 0.0341
Echinococcus granulosus 7TM GPCR rhodopsin 0.0082 0.1385 0.139
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Echinococcus granulosus glycine receptor subunit alpha 1 0.0073 0.1179 0.1182
Brugia malayi Sugar transporter family protein 0.0029 0.0168 0.0238
Brugia malayi prostaglandin transporter 0.0055 0.0772 0.1147
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0025 0.0061 0.0042
Onchocerca volvulus Neuropeptide F receptor homolog 0.0082 0.1385 0.2784
Plasmodium vivax lysophospholipase, putative 0.0146 0.2867 1
Schistosoma mansoni voltage-gated potassium channel 0.0107 0.1955 0.1953
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0772 0.1147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0183 0.0257
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0194 0.0195
Loa Loa (eye worm) hypothetical protein 0.0038 0.0367 0.0529
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.2786 0.564
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0205 0.4229 0.6347
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0073 0.1179 0.1174
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0913 0.3161
Echinococcus granulosus transient receptor potential cation channel 0.0023 0.0022 0.0022
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0183 0.0183
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0025 0.0061 0.0042
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0037 0.0341 0.0322
Entamoeba histolytica P-glycoprotein-5 0.0031 0.0219 0.0192
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1985 0.7117
Loa Loa (eye worm) hypothetical protein 0.0038 0.0367 0.0529
Brugia malayi ecdysteroid receptor 0.003 0.0183 0.0261
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0022 0.0009 0.0009
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0874 0.177
Plasmodium falciparum esterase, putative 0.0146 0.2867 1
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1138 0.4066
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Mycobacterium ulcerans 6-phosphofructokinase 0.0108 0.1985 0.7107
Onchocerca volvulus 0.0082 0.1385 0.2784
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0025 0.0061 0.0042
Loa Loa (eye worm) carboxylesterase 0.0023 0.0019 0.0014
Echinococcus multilocularis solute carrier family 22 0.0029 0.0168 0.0168
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Schistosoma mansoni hypothetical protein 0.0031 0.0214 0.0206
Echinococcus granulosus allatostatin A receptor 0.0082 0.1385 0.139
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0046 0.0552 0.0554
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.2242 0.2227
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0183 0.0261
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0367 0.0537
Onchocerca volvulus 0.0029 0.0168 0.032
Schistosoma mansoni hypothetical protein 0.0082 0.1385 0.1381
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0099 0.1771 0.2649
Loa Loa (eye worm) hypothetical protein 0.0071 0.1138 0.1671
Echinococcus multilocularis glycine receptor subunit beta 0.0073 0.1179 0.1182
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.1966 0.1951
Echinococcus multilocularis neuropeptide receptor 0.0082 0.1385 0.139
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0122 0.2321 0.2328
Onchocerca volvulus 0.0082 0.1385 0.2784
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0183 0.0174
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.2197 0.2204
Echinococcus granulosus FTZ F1 alpha 0.003 0.0183 0.0183
Brugia malayi hypothetical protein 0.0121 0.2284 0.3421
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) hypothetical protein 0.0055 0.0772 0.1129
Schistosoma mansoni neuropeptide receptor 0.0082 0.1385 0.1381
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0034 0.0276 0.0277
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0073 0.1179 0.1174
Schistosoma mansoni cpg binding protein 0.0034 0.0271 0.0263
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0886 0.3067
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.1385 0.139
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.1079 0.1074
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.1007 0.101
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0219 0.022
Leishmania major p-glycoprotein 0.0031 0.0219 0.0755
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0276 0.096
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0025 0.0061 0.0152
Brugia malayi major facilitator superfamily protein 0.0029 0.0168 0.0238
Loa Loa (eye worm) hypothetical protein 0.0071 0.1138 0.1671
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.1385 0.139
Echinococcus multilocularis multidrug resistance protein 1 0.0031 0.0219 0.022
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0363 0.7866 0.7888
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0082 0.1385 0.2037
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0194 0.0186
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0886 0.088
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0265 0.0266
Schistosoma mansoni multidrug resistance protein 0.0031 0.0219 0.021
Onchocerca volvulus 0.0082 0.1385 0.2784
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0052 0.0689 0.0692
Trichomonas vaginalis set domain proteins, putative 0.0236 0.4939 1
Mycobacterium tuberculosis Probable reductase 0.0107 0.1966 0.1951
Leishmania major hypothetical protein, conserved 0.0034 0.0276 0.096
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Onchocerca volvulus 0.0029 0.0168 0.032
Echinococcus granulosus transient receptor potential gamma protein 0.0022 0.0009 0.0009
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0082 0.1385 0.139
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0025 0.0061 0.0042
Loa Loa (eye worm) hypothetical protein 0.0055 0.0772 0.1129
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0772 0.1543
Brugia malayi Carboxylesterase family protein 0.0135 0.2601 0.3899
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0025 0.0061 0.0186
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0125 0.2389 0.857
Leishmania major cytochrome p450-like protein 0.0025 0.0061 0.0186
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0031 0.0219 0.031
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0772 0.2669
Echinococcus granulosus g protein coupled receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0194 0.0195
Echinococcus multilocularis transient receptor potential cation channel 0.0022 0.0009 0.0009
Echinococcus multilocularis expressed protein 0.0414 0.9055 0.9081
Loa Loa (eye worm) hypothetical protein 0.0071 0.1138 0.1671
Brugia malayi hypothetical protein 0.0025 0.0072 0.0094
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Leishmania major DNA polymerase eta, putative 0.0033 0.0265 0.092
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0183 0.0257
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0874 0.3115
Schistosoma mansoni thyroid hormone receptor 0.0155 0.3068 0.3071
Schistosoma mansoni multidrug resistance protein 0.0031 0.0219 0.021
Loa Loa (eye worm) neuropeptide F receptor 0.0082 0.1385 0.2037
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0183 0.0183
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0205 0.4229 0.4236
Trypanosoma brucei unspecified product 0.0053 0.0723 0.257
Plasmodium falciparum thioredoxin reductase 0.0047 0.0578 0.1811
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0276 0.096
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0147 0.0138
Mycobacterium tuberculosis Conserved protein 0.0071 0.1138 0.1122
Brugia malayi phosphofructokinase 0.0108 0.1985 0.2972
Echinococcus granulosus ankyrin repeat protein 0.0363 0.7866 0.789
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.1138 0.1122
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0168 0.057
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0874 0.3115
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0031 0.0219 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0772 0.1129
Loa Loa (eye worm) acetylcholinesterase 1 0.0135 0.2601 0.3837
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0265 0.0378
Leishmania major cytochrome p450-like protein 0.0033 0.0262 0.091
Loa Loa (eye worm) hypothetical protein 0.0066 0.1018 0.1492
Echinococcus granulosus biogenic amine 5HT receptor 0.0082 0.1385 0.139
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0205 0.4229 0.4242
Plasmodium falciparum lysophospholipase, putative 0.0143 0.2786 0.9711
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0143 0.2786 0.9701
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0014
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.0367 0.0537
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0219 0.0443
Echinococcus granulosus dna polymerase eta 0.0033 0.0265 0.0266
Mycobacterium ulcerans lipase LipD 0.0071 0.1138 0.4046
Brugia malayi Cytochrome P450 family protein 0.0025 0.0061 0.0078
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0183 0.0261
Echinococcus multilocularis transient receptor potential cation channel 0.0023 0.0022 0.0022
Schistosoma mansoni transient receptor potential channel 0.0022 0.0009 0.00000011692
Plasmodium vivax unspecified product 0.0146 0.2867 1
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0125 0.2389 0.857
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.1007 0.15
Onchocerca volvulus 0.0055 0.0772 0.1543
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.1138 0.1122
Schistosoma mansoni neuropeptide F-like receptor 0.0082 0.1385 0.1381
Echinococcus granulosus serotonin receptor 0.0082 0.1385 0.139
Schistosoma mansoni glucose transport protein 0.0029 0.0168 0.0159
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0168 0.0553
Loa Loa (eye worm) voltage-gated potassium channel 0.0028 0.0147 0.0204
Schistosoma mansoni growth hormone secretagogue receptor 0.0082 0.1385 0.1381
Onchocerca volvulus 0.003 0.0194 0.0374
Schistosoma mansoni amine GPCR 0.0082 0.1385 0.1381
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.1138 0.1122
Echinococcus granulosus transient receptor potential cation channel 0.0022 0.0009 0.0009
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0082 0.1385 0.1381
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0168 0.0168
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0168 0.057
Echinococcus multilocularis expressed protein 0.0038 0.0367 0.0368
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0082 0.1385 0.1381
Echinococcus multilocularis neuropeptides capa receptor 0.0082 0.1385 0.139
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Plasmodium vivax PST-A protein 0.0143 0.2786 0.9711
Loa Loa (eye worm) hypothetical protein 0.0071 0.1138 0.1671
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0147 0.0138
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Loa Loa (eye worm) G-protein coupled receptor 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0046 0.0552 0.0803
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0135 0.2601 0.2602
Schistosoma mansoni hypothetical protein 0.0036 0.0319 0.031
Echinococcus multilocularis ankyrin repeat protein 0.0363 0.7866 0.789
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0276 0.096
Trypanosoma brucei monoglyceride lipase, putative 0.0143 0.2786 1
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0265 0.0384
Trypanosoma brucei THT1 - hexose transporter, putative 0.0029 0.0168 0.057
Echinococcus multilocularis neuroligin 0.0023 0.0019 0.0019
Echinococcus granulosus transient receptor potential cation channel 0.0022 0.0009 0.0009
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0057 0.0799 0.0802
Echinococcus granulosus two pore calcium channel protein 2 0.0022 0.0009 0.0009
Schistosoma mansoni inositol monophosphatase 0.0041 0.044 0.0432
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.044 0.0891
Brugia malayi Inositol-1 0.0041 0.044 0.0648
Brugia malayi glutathione reductase 0.0047 0.0578 0.0855
Echinococcus multilocularis thyroid hormone receptor alpha 0.0155 0.3068 0.3077
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0143 0.2786 0.564
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0578 0.2047
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0082 0.1385 0.139
Toxoplasma gondii hypothetical protein 0.0073 0.117 0.4063
Loa Loa (eye worm) hypothetical protein 0.0055 0.0772 0.1129
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0108 0.1985 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) hypothetical protein 0.0071 0.1138 0.1671
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0168 0.0537
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.1385 0.139
Schistosoma mansoni hypothetical protein 0.0029 0.0168 0.0159
Onchocerca volvulus 0.0029 0.0168 0.032
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0031 0.0219 0.02
Brugia malayi follicle stimulating hormone receptor 0.031 0.6658 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0183 0.0351
Echinococcus multilocularis neuropeptide receptor 0.0082 0.1385 0.139
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Schistosoma mansoni neuropeptide F-like receptor 0.0082 0.1385 0.1381
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0205 0.4229 0.4242
Schistosoma mansoni BC026374 protein (S09 family) 0.0023 0.0019 0.001
Echinococcus multilocularis agrin 0.0038 0.0367 0.0368
Echinococcus multilocularis dna polymerase eta 0.0033 0.0265 0.0266
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.1138 0.2305
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.1138 0.1142
Schistosoma mansoni neuropeptide f receptor 76f 0.0082 0.1385 0.1381
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.428 0.6322
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0262 0.0878
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0319 0.031
Brugia malayi Carboxylesterase family protein 0.0023 0.0019 0.0014
Loa Loa (eye worm) multidrug resistance protein 3 0.0031 0.0219 0.031
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0073 0.1179 0.1182
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0028 0.0147 0.0147
Schistosoma mansoni hypothetical protein 0.0082 0.1385 0.1381
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0194 0.0647
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Mycobacterium ulcerans beta-lactamase 0.0071 0.1138 0.4046
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0143 0.2786 0.564
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0168 0.0159
Schistosoma mansoni agrin 0.0038 0.0367 0.0359
Entamoeba histolytica P-glycoprotein-2 0.0031 0.0219 0.0192
Schistosoma mansoni amine GPCR 0.0082 0.1385 0.1381
Echinococcus granulosus g protein coupled receptor 0.0082 0.1385 0.139
Echinococcus multilocularis dro:myosuppressin receptor 0.0082 0.1385 0.139
Schistosoma mansoni acetylcholinesterase 0.0023 0.0019 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0143 0.2786 0.564
Echinococcus granulosus glycine receptor subunit alpha 1 0.0073 0.1179 0.1182
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0832 0.0835
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.044 0.1551
Leishmania major ATP-dependent phosphofructokinase 0.0108 0.1985 0.7117
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0183 0.0261
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0367 0.0537
Echinococcus granulosus transcription factor Dp 1 0.0038 0.037 0.0371
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0219 0.0443
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0199 0.019
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0338
Onchocerca volvulus 0.0038 0.0367 0.0723
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0025 0.0061 0.0152
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0025 0.0061 0.0152
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.023 0.0326
Onchocerca volvulus 0.0029 0.0168 0.032
Echinococcus multilocularis somatostatin receptor 0.0082 0.1385 0.139
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.1138 0.1133
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0194 0.0186
Echinococcus granulosus alpha 1A adrenergic receptor 0.0082 0.1385 0.139
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0194 0.0186
Plasmodium falciparum hexose transporter 0.0029 0.0168 0.0343
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0832 0.0835
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0262 0.0374
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0025 0.0061 0.0042
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.1007 0.3111
Echinococcus granulosus geminin 0.0168 0.3378 0.3388
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0031 0.0219 0.0733
Echinococcus granulosus two pore calcium channel protein 1 0.0022 0.0009 0.0009
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0065 0.099 0.1476
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Brugia malayi nuclear receptor NHR-88 0.003 0.0183 0.0261
Trypanosoma brucei DNA polymerase IV, putative 0.0053 0.0723 0.257
Echinococcus granulosus potassium voltage gated channel protein 0.0046 0.0552 0.0554
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0265 0.0256
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0167 0.0552
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Onchocerca volvulus 0.0071 0.1138 0.2284
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Echinococcus multilocularis ATP binding cassette sub family B 0.0031 0.0211 0.0212
Echinococcus granulosus g-protein coupled receptor 0.0082 0.1385 0.139
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.044 0.0891
Echinococcus granulosus short transient receptor potential channel 6 0.0023 0.0022 0.0022
Loa Loa (eye worm) sugar transporter 0.0029 0.0168 0.0234
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0262 0.091
Entamoeba histolytica phosphofructokinase, putative 0.0108 0.1985 0.6736
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0014
Onchocerca volvulus 0.0055 0.0772 0.1543
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0014
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0219 0.022
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0082 0.1385 0.139
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0057 0.0799 0.1188
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0265 0.0266
Echinococcus multilocularis calcium activated potassium channel 0.0022 0.0009 0.0009
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0877 0.0871
Leishmania major glucose transporter, lmgt1 0.0029 0.0168 0.057
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0168 0.0234
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Leishmania major cytochrome p450-like protein 0.0025 0.0061 0.0186
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0082 0.1385 0.139
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0168 0.0537
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0057 0.0799 0.1169
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Echinococcus granulosus neuropeptide Y receptor 0.0082 0.1385 0.139
Brugia malayi Cation transporter family protein 0.0073 0.1179 0.1759
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0027 0.0121 0.0121
Brugia malayi beta-lactamase family protein 0.0071 0.1138 0.1698
Loa Loa (eye worm) hypothetical protein 0.0073 0.117 0.1718
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0027 0.0121 0.0121
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0023 0.0019 0.001
Schistosoma mansoni myosin xvIII 0.0082 0.1385 0.1381
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0219 0.0443
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0338
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0265 0.092
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) carboxylesterase 0.0023 0.0019 0.0014
Brugia malayi G-protein coupled receptor 0.0082 0.1385 0.207
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0072 0.0218
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0121 0.0121
Echinococcus multilocularis transfer RNA-Gly 0.0028 0.0147 0.0147
Echinococcus granulosus multidrug resistance protein 1 0.0031 0.0219 0.022
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.1385 0.139
Echinococcus multilocularis hyperpolarization activated cyclic 0.0027 0.0121 0.0121
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0107 0.1955 0.2926
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0052 0.0689 0.0692
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0183 0.0261
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Trypanosoma cruzi monoglyceride lipase, putative 0.0143 0.2786 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.1385 0.139
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0183 0.0174
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0367 0.125
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0082 0.1385 0.1381
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0578 0.0579
Brugia malayi G protein-coupled receptor 0.0082 0.1385 0.207
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0025 0.0061 0.0152
Schistosoma mansoni sugar transporter 0.0029 0.0168 0.0159
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0046 0.0552 0.0554
Schistosoma mansoni cpg binding protein 0.0034 0.0271 0.0263
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0099 0.1771 0.2607
Brugia malayi larval opioid receptor 0.0082 0.1385 0.207
Echinococcus granulosus cytochrome P450 2K1 0.0025 0.0061 0.0061
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0167 0.0341
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0025 0.0061 0.0152
Schistosoma mansoni opsin-like receptor 0.0082 0.1385 0.1381
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0183 0.0261
Loa Loa (eye worm) hypothetical protein 0.0055 0.0772 0.1129
Brugia malayi putative neuropeptide receptor NPR1 0.0082 0.1385 0.207
Echinococcus granulosus agrin 0.0038 0.0367 0.0368
Echinococcus multilocularis acetylcholinesterase 0.0135 0.2601 0.2609
Brugia malayi G-protein coupled receptor 0.0082 0.1385 0.207
Schistosoma mansoni amine GPCR 0.0082 0.1385 0.1381
Plasmodium falciparum lysophospholipase, putative 0.0143 0.2786 0.9711
Brugia malayi Cytochrome P450 family protein 0.0033 0.0262 0.038
Leishmania major hypothetical protein, conserved 0.0071 0.1138 0.4066
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Trypanosoma brucei unspecified product 0.0023 0.0026 0.0058
Brugia malayi Serotonin receptor 0.0082 0.1385 0.207
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.1138 0.1122
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0028 0.0147 0.0147
Echinococcus multilocularis transient receptor potential cation channel 0.0022 0.0009 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0338
Echinococcus granulosus sodium leak channel non selective protein 0.0022 0.0009 0.0009
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.044 0.1551
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0025 0.0061 0.0042
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0367 0.125
Loa Loa (eye worm) voltage-gated potassium channel 0.0024 0.0036 0.004
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.00000017239
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Onchocerca volvulus 0.0029 0.0168 0.032
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0022 0.0009 0.0009
Plasmodium falciparum lysophospholipase, putative 0.0146 0.2867 1
Echinococcus granulosus acetylcholinesterase 0.0135 0.2601 0.2609
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0183 0.0261
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0219 0.022
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0034 0.0276 0.0277
Echinococcus granulosus g protein coupled receptor 0.0082 0.1385 0.139
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0874 0.3115
Schistosoma mansoni multidrug resistance protein 0.0031 0.0219 0.021
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0065 0.099 0.0993
Trypanosoma brucei monoglyceride lipase, putative 0.0143 0.2786 1
Onchocerca volvulus 0.0082 0.1385 0.2784
Schistosoma mansoni transient receptor potential channel 0.0023 0.0022 0.0013
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0025 0.0061 0.0042
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0143 0.2786 0.564
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0121 0.0165
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0125 0.2379 0.2387
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0772 0.1147
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Plasmodium falciparum glutathione reductase 0.0047 0.0578 0.1811
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) hypothetical protein 0.0073 0.1179 0.1731
Echinococcus granulosus dnaJ subfamily B 0.0454 0.997 1
Brugia malayi Carboxylesterase family protein 0.0023 0.0019 0.0014
Echinococcus multilocularis glycine receptor subunit beta 0.0073 0.1179 0.1182
Trypanosoma brucei glucose transporter 1E 0.0029 0.0168 0.057
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Leishmania major monoglyceride lipase, putative 0.0143 0.2786 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0205 0.4229 0.4242
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0072 0.0224
Schistosoma mansoni biogenic amine (5HT) receptor 0.0082 0.1385 0.1381
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0082 0.1385 0.1381
Echinococcus granulosus neuropeptide s receptor 0.0082 0.1385 0.139
Trichomonas vaginalis spcc417.12 protein, putative 0.0023 0.0019 0.0038
Schistosoma mansoni alpha-1 adrenergic receptor 0.0082 0.1385 0.1381
Echinococcus multilocularis voltage gated potassium channel 0.0028 0.0147 0.0147
Echinococcus multilocularis ryanodine receptor 44f 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.1138 0.1122
Schistosoma mansoni histamine h1 receptor 0.0082 0.1385 0.1381
Echinococcus granulosus short transient receptor potential channel 6 0.0022 0.0009 0.0009
Plasmodium vivax hexose transporter 0.0029 0.0168 0.0343
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.1385 0.139
Schistosoma mansoni jumonji/arid domain-containing protein 0.006 0.0874 0.0868
Schistosoma mansoni hypothetical protein 0.0025 0.0061 0.0052
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0027 0.0121 0.0121
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0262 0.091
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0219 0.022
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.1138 0.4066
Toxoplasma gondii ABC1 family protein 0.0071 0.1138 0.3951
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0167 0.0552
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Echinococcus granulosus potassium voltage gated channel protein 0.0028 0.0147 0.0147
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0219 0.0443
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0276 0.096
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.1395 0.1391
Brugia malayi Dopamine receptor protein 1 0.0082 0.1385 0.207
Echinococcus granulosus neuropeptide Y receptor 0.0082 0.1385 0.139
Schistosoma mansoni voltage-gated potassium channel 0.0026 0.0087 0.0078
Onchocerca volvulus 0.0029 0.0168 0.032
Schistosoma mansoni lipoxygenase 0.0117 0.2197 0.2196
Onchocerca volvulus 0.0082 0.1385 0.2784
Brugia malayi Carboxylesterase family protein 0.0023 0.0019 0.0014
Schistosoma mansoni sugar transporter 0.0029 0.0168 0.0159
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Loa Loa (eye worm) hypothetical protein 0.0205 0.4229 0.6246
Echinococcus multilocularis BC026374 protein (S09 family) 0.0023 0.0019 0.0019
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0276 0.096
Echinococcus granulosus calcium activated potassium channel 0.0022 0.0009 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0108 0.1985 0.4019
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0121 0.0121
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) hypothetical protein 0.0073 0.117 0.1718
Loa Loa (eye worm) hypothetical protein 0.0071 0.1138 0.1671
Schistosoma mansoni opsin-like receptor 0.0082 0.1385 0.1381
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0874 0.3115
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Schistosoma mansoni 60S ribosomal protein L21 0.0026 0.0087 0.0078
Schistosoma mansoni cytochrome P450 0.0025 0.0061 0.0052
Echinococcus multilocularis potassium voltage gated channel protein 0.0107 0.1955 0.196
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0082 0.1385 0.1381
Brugia malayi Carboxylesterase family protein 0.0135 0.2601 0.3899
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0168 0.057
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0143 0.2786 0.564
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0031 0.0211 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0874 0.128
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0028 0.0147 0.0207
Schistosoma mansoni cpg binding protein 0.0032 0.023 0.0221
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0265 0.0256
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0183 0.0174
Giardia lamblia Hexose transporter 0.0029 0.0168 0.0021
Brugia malayi neuropeptide F receptor 0.0082 0.1385 0.207
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0082 0.1385 0.139
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0143 0.2786 0.564
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.1385 0.139
Brugia malayi putative neuropeptide receptor 0.0082 0.1385 0.207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0125 0.2379 0.2387
Schistosoma mansoni voltage-gated potassium channel 0.0105 0.1911 0.1909
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0874 0.3091
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0772 0.0774
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.1385 0.1381
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.1385 0.139
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0194 0.0195
Onchocerca volvulus 0.0236 0.4952 1
Schistosoma mansoni transient receptor potential channel 0.0022 0.0009 0.00000011692
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.105 0.1566
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0031 0.0211 0.0212
Echinococcus multilocularis 6 phosphofructokinase 0.0108 0.1985 0.1991
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0167 0.0341
Loa Loa (eye worm) G-protein coupled receptor 0.0082 0.1385 0.2037
Onchocerca volvulus 0.0082 0.1385 0.2784
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0214 0.0303
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0183 0.0174
Echinococcus granulosus voltage gated potassium channel 0.0028 0.0147 0.0147
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Brugia malayi hypothetical protein 0.0082 0.1385 0.207
Echinococcus multilocularis follistatin 0.0038 0.0367 0.0368
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0183 0.0261
Loa Loa (eye worm) hypothetical protein 0.0052 0.0688 0.1004
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0108 0.1985 0.7062
Brugia malayi beta-lactamase family protein 0.0071 0.1138 0.1698
Echinococcus granulosus 6 phosphofructokinase 0.0108 0.1985 0.1991
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0025 0.0061 0.0152
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0028 0.0147 0.0147
Loa Loa (eye worm) 6-phosphofructokinase 0.0108 0.1985 0.2925
Onchocerca volvulus 0.0082 0.1385 0.2784
Echinococcus multilocularis conserved hypothetical protein 0.0046 0.0552 0.0554
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0183 0.0261
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0886 0.0868
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0082 0.1385 0.207
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0168 0.0149
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0168 0.057
Onchocerca volvulus 0.0082 0.1385 0.2784
Schistosoma mansoni sugar transporter 0.0029 0.0168 0.0159
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.044 0.0891
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0023 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus multilocularis orexin receptor type 2 0.0082 0.1385 0.139
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0219 0.0443
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0073 0.1179 0.1182
Brugia malayi Sugar transporter family protein 0.0029 0.0168 0.0238
Echinococcus multilocularis G protein coupled receptor 139 0.0082 0.1385 0.139
Onchocerca volvulus 0.0029 0.0168 0.032
Loa Loa (eye worm) inositol-1 0.0041 0.044 0.0637
Echinococcus multilocularis 0.0025 0.0061 0.0061
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0082 0.1385 0.1381
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0183 0.0257
Echinococcus multilocularis solute carrier family 22 0.0029 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Schistosoma mansoni voltage-gated cation channel 0.0205 0.4229 0.4236
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0183 0.0261
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0276 0.096
Brugia malayi Cytochrome P450 family protein 0.0033 0.0262 0.038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0183 0.0257
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0072 0.0224
Brugia malayi 6-phosphofructokinase 0.0108 0.1993 0.2984
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0219 0.022
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0027 0.0121 0.0112
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0168 0.0339
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0031 0.0207 0.0208
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0029 0.0168 0.0168
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0082 0.1385 0.2784
Loa Loa (eye worm) hypothetical protein 0.0095 0.1686 0.2481
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0167 0.0552
Schistosoma mansoni glucose transport protein 0.0029 0.0168 0.0159
Echinococcus multilocularis neuropeptide Y receptor 0.0082 0.1385 0.139
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0082 0.1385 0.139
Brugia malayi Thioredoxin reductase 0.0047 0.0578 0.0855
Brugia malayi hypothetical protein 0.0055 0.0772 0.1147
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0027 0.0121 0.0121
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0143 0.2786 0.564
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.1007 0.1477
Loa Loa (eye worm) hypothetical protein 0.0107 0.1955 0.2879
Plasmodium falciparum esterase, putative 0.0146 0.2867 1
Onchocerca volvulus 0.0023 0.0019 0.0019
Trypanosoma brucei glucose transporter, putative 0.0029 0.0168 0.057
Schistosoma mansoni hypothetical protein 0.0031 0.0214 0.0206
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0219 0.0443
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0147 0.0138
Schistosoma mansoni hypothetical protein 0.0031 0.0214 0.0206
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0029 0.0168 0.0168
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0027 0.0121 0.0165
Brugia malayi hypothetical protein 0.0023 0.0019 0.0014
Brugia malayi G protein-coupled receptor F59B2.13 0.0082 0.1385 0.207
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0108 0.1985 0.7117
Toxoplasma gondii hypothetical protein 0.0146 0.2867 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Echinococcus granulosus tachykinin peptides receptor 99D 0.0082 0.1385 0.139
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Brugia malayi neuropeptide F receptor 0.0082 0.1385 0.207
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.1007 0.3593
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0219 0.022
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0772 0.1147
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.1138 0.1122
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Echinococcus granulosus glycine receptor subunit beta 0.0073 0.1179 0.1182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Loa Loa (eye worm) hypothetical protein 0.0023 0.0019 0.0014
Loa Loa (eye worm) phosphofructokinase 0.0108 0.1985 0.2925
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Schistosoma mansoni glucose transport protein 0.0029 0.0168 0.0159
Loa Loa (eye worm) hypothetical protein 0.0029 0.0168 0.0234
Brugia malayi Melatonin receptor type 1A 0.0082 0.1385 0.207
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0023 0.0019 0.0038
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0214 0.0215
Loa Loa (eye worm) hypothetical protein 0.0315 0.6765 1
Entamoeba histolytica P-glycoprotein-2, putative 0.0031 0.0219 0.0192
Echinococcus granulosus neuropeptide receptor 0.0082 0.1385 0.139
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0183 0.0174
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.1138 0.1698
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0183 0.0183
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0022 0.0009 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0167 0.0338
Loa Loa (eye worm) carboxylesterase 0.0135 0.2601 0.3837
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0022 0.0009 0.0009
Echinococcus multilocularis short transient receptor potential channel 6 0.0022 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.003 0.0183 0.0257
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0874 0.177
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0023 0.0019 0.0019
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0262 0.091
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0029 0.0174 0.0244
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0025 0.0061 0.0042
Mycobacterium ulcerans hypothetical protein 0.0143 0.2786 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0019
Mycobacterium leprae Probable lipase LipE 0.0071 0.1138 0.3954
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0072 0.0224
Loa Loa (eye worm) hypothetical protein 0.0037 0.0343 0.0493
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0367 0.0537
Schistosoma mansoni hypothetical protein 0.0168 0.3378 0.3382
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0168 0.0537
Onchocerca volvulus 0.0023 0.0019 0.0019
Echinococcus multilocularis g protein coupled receptor 0.0082 0.1385 0.139
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0028 0.0147 0.0147
Schistosoma mansoni voltage-gated potassium channel 0.006 0.0877 0.0871
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0772 0.0774
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0177 0.0603
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0027 0.0121 0.0121
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0031 0.0199 0.0285
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Schistosoma mansoni DNA polymerase eta 0.0033 0.0265 0.0256
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0367 0.125
Schistosoma mansoni vesicular amine transporter 0.0028 0.0147 0.0138
Schistosoma mansoni neuropeptide receptor 0.0082 0.1385 0.1381
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0143 0.2786 0.9701
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0073 0.1179 0.1174
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0214 0.0215
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0027 0.0121 0.0112
Mycobacterium leprae conserved hypothetical protein 0.0071 0.1138 0.3954
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0168 0.0238
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0343 0.12
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0183 0.0351
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.044 0.0441
Echinococcus granulosus potassium voltage gated channel protein 0.0107 0.1955 0.196
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.1385 0.139
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0082 0.1385 0.139
Echinococcus granulosus GPCR family 2 0.0031 0.0214 0.0215
Echinococcus granulosus sodium channel protein 0.0092 0.1618 0.1623
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.1138 0.1122
Echinococcus granulosus somatostatin receptor 0.0082 0.1385 0.139
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0168 0.0339
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0025 0.0061 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0183 0.0261
Echinococcus granulosus peptide allatostatin:somatostatin 0.0082 0.1385 0.139
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0025 0.0061 0.0152
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0183 0.0183
Brugia malayi hypothetical protein 0.0029 0.0168 0.0238
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0183 0.0261
Loa Loa (eye worm) hypothetical protein 0.0022 0.0009 0.00000017239
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0578 0.0841
Echinococcus multilocularis para nitrobenzyl esterase 0.0023 0.0019 0.0019
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0284 0.0574
Onchocerca volvulus 0.0029 0.0168 0.032
Echinococcus granulosus potassium voltage gated channel protein 0.0105 0.1911 0.1916
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0168 0.057
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0168 0.0339
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0168 0.057
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0874 0.3115
Loa Loa (eye worm) hypothetical protein 0.0038 0.0367 0.0529
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Schistosoma mansoni voltage-gated potassium channel 0.0031 0.0199 0.019
Brugia malayi steroid hormone receptor 0.003 0.0183 0.0261
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Echinococcus granulosus neuropeptides capa receptor 0.0082 0.1385 0.139
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0214 0.0215
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.1966 0.1951
Schistosoma mansoni hypothetical protein 0.0031 0.0214 0.0206
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0025 0.0061 0.0042
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0183 0.0174
Echinococcus multilocularis carboxylesterase 5A 0.0135 0.2601 0.2609
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0025 0.0061 0.0042
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0082 0.1385 0.207
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0082 0.1385 0.1381
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0183 0.0183
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0082 0.1385 0.139
Brugia malayi Sugar transporter family protein 0.0029 0.0168 0.0238
Loa Loa (eye worm) hypothetical protein 0.0082 0.1385 0.2037
Onchocerca volvulus 0.0055 0.0772 0.1543

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.6 uM Inhibition of specific binding of [3H]-CPX to the A1 adenosine receptor in DDT1 MF-2 (DDT) cells. ChEMBL. 8064798
IC50 (binding) = 2.6 uM Inhibition of specific binding of [3H]-CPX to the A1 adenosine receptor in DDT1 MF-2 (DDT) cells. ChEMBL. 8064798
Kd (binding) = 0.86 nM Specific binding of [3H]-CPX to the A1-adenosine receptor ChEMBL. 8064798
Kd (binding) = 0.86 nM Specific binding of [3H]-CPX to the A1-adenosine receptor ChEMBL. 8064798
Loss (binding) = 30 % Loss of specific binding of [3H]-CPX to the A1-adenosine receptor of DDT1 MF-2 (DDT) cells at a concentration of 10 uM ChEMBL. 8064798
Loss (binding) = 30 % Loss of specific binding of [3H]-CPX to the A1-adenosine receptor of DDT1 MF-2 (DDT) cells at a concentration of 10 uM ChEMBL. 8064798

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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