Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | sedoheptulose-1,7-bisphosphatase | 0.0121 | 0.0794 | 0.2525 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0239 | 0.2157 | 0.6856 |
Brugia malayi | fructose-1,6-bisphosphatase | 0.0325 | 0.3146 | 1 |
Toxoplasma gondii | fructose-bisphospatase I | 0.0121 | 0.0794 | 0.2525 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0239 | 0.2157 | 0.2157 |
Toxoplasma gondii | sedoheptulose-1,7-bisphosphatase | 0.0121 | 0.0794 | 0.2525 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0121 | 0.0794 | 0.2525 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.2157 | 0.6856 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0187 | 0.1559 | 0.4956 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0187 | 0.1559 | 0.1559 |
Trypanosoma cruzi | sedoheptulose-1,7-bisphosphatase, putative | 0.0121 | 0.0794 | 0.2525 |
Echinococcus multilocularis | fructose 1,6 bisphosphatase 1 | 0.0325 | 0.3146 | 0.3146 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0239 | 0.2157 | 0.2157 |
Echinococcus granulosus | fructose 16 bisphosphatase 1 | 0.0325 | 0.3146 | 0.3146 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0325 | 0.3146 | 1 |
Schistosoma mansoni | fructose-16-bisphosphatase-related | 0.0325 | 0.3146 | 1 |
Loa Loa (eye worm) | fructose-1,6-bisphosphatase | 0.0325 | 0.3146 | 1 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0187 | 0.1559 | 0.4956 |
Trypanosoma cruzi | fructose-1,6-bisphosphatase, cytosolic, putative | 0.0325 | 0.3146 | 1 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0239 | 0.2157 | 0.6856 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0239 | 0.2157 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0239 | 0.2157 | 0.2157 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0239 | 0.2157 | 0.2157 |
Trypanosoma brucei | fructose-1,6-bisphosphatase | 0.0325 | 0.3146 | 1 |
Toxoplasma gondii | fructose-bisphospatase II | 0.0325 | 0.3146 | 1 |
Leishmania major | 0.0325 | 0.3146 | 1 | |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0187 | 0.1559 | 0.1559 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.