Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Kinase, CMGC GSK | 0.016 | 0.1875 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0407 | 0.1101 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Loa Loa (eye worm) | oxidoreductase | 0.0068 | 0.0704 | 0.1907 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0199 | 0.0632 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0407 | 0.1101 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0195 | 0.0195 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0079 | 0.0213 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0707 | 0.1914 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0342 | 0.0926 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.013 | 0.0353 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.016 | 0.1875 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.013 | 0.132 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0707 | 0.0707 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0126 | 0.0548 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.013 | 0.0725 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0038 | 0.0315 | 0.0315 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0323 | 0.1201 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0707 | 0.1914 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.013 | 0.057 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0199 | 0.0538 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.036 | 0.1534 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0199 | 0.0788 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0068 | 0.0704 | 0.3673 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0407 | 0.1513 |
Onchocerca volvulus | 0.0068 | 0.0704 | 0.3459 | |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.016 | 0.1875 | 0.5077 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0199 | 0.0788 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0407 | 0.1101 |
Schistosoma mansoni | acetylcholinesterase | 0.0038 | 0.0315 | 0.0854 |
Leishmania major | prostaglandin f synthase, putative | 0.0068 | 0.0704 | 0.3673 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0038 | 0.0315 | 0.0854 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0315 | 0.0854 |
Leishmania major | aldo-keto reductase-like protein | 0.0068 | 0.0704 | 0.3673 |
Giardia lamblia | Aldose reductase | 0.0068 | 0.0704 | 0.3408 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.016 | 0.1875 | 0.5077 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0299 | 0.1114 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.013 | 0.1158 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.002 | 0.0085 | 0.0318 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.013 | 0.0251 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Schistosoma mansoni | ran | 0.0021 | 0.0099 | 0.0269 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0195 | 0.0917 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.036 | 0.1534 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0315 | 0.0854 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0199 | 0.0538 |
Schistosoma mansoni | hypothetical protein | 0.0303 | 0.3692 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0224 | 0.2688 | 0.7279 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0068 | 0.0704 | 0.262 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0068 | 0.0704 | 0.262 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0038 | 0.0315 | 0.0854 |
Entamoeba histolytica | aldose reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.013 | 0.1158 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.013 | 0.0353 |
Onchocerca volvulus | 0.0038 | 0.0315 | 0.1285 | |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0315 | 0.0854 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0284 | 0.0768 |
Plasmodium vivax | aldehyde reductase, putative | 0.002 | 0.0085 | 0.0166 |
Echinococcus multilocularis | neuroligin | 0.0038 | 0.0315 | 0.0315 |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0315 | 0.1174 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0055 | 0.0149 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0047 | 0.0127 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0038 | 0.0315 | 0.0854 |
Echinococcus multilocularis | aldo keto reductase | 0.0068 | 0.0704 | 0.0704 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0126 | 0.0228 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0038 | 0.0315 | 0.0854 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.013 | 0.1158 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0582 | 0.1575 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.013 | 0.0485 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0407 | 0.0407 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0047 | 0.0127 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.016 | 0.1875 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0126 | 0.0228 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0099 | 0.0269 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0784 | 0.2124 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0099 | 0.0369 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0126 | 0.0228 |
Echinococcus multilocularis | protein kinase shaggy | 0.016 | 0.1875 | 0.1875 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0068 | 0.0704 | 0.3459 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0079 | 0.0213 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0228 | 0.0228 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.0025 | 0.0067 |
Entamoeba histolytica | aldose reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Loa Loa (eye worm) | oxidoreductase | 0.0068 | 0.0704 | 0.1907 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0199 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0315 | 0.0854 |
Onchocerca volvulus | 0.0023 | 0.013 | 0.0251 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0038 | 0.0315 | 0.4119 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0055 | 0.0148 |
Mycobacterium tuberculosis | Conserved protein | 0.002 | 0.0085 | 0.0641 |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0315 | 0.1174 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.046 | 0.1245 |
Plasmodium falciparum | aldehyde reductase, putative | 0.002 | 0.0085 | 0.0166 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.016 | 0.1875 | 0.5077 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.002 | 0.0085 | 0.0085 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0228 | 0.0849 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0199 | 0.0632 |
Trichomonas vaginalis | CMGC family protein kinase | 0.016 | 0.1875 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0049 | 0.0452 | 0.5922 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0199 | 0.0632 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0038 | 0.0315 | 0.0854 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.013 | 0.057 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0069 | 0.0707 | 0.1914 |
Trypanosoma cruzi | aldo-keto reductase | 0.0068 | 0.0704 | 0.3673 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0068 | 0.0704 | 1 |
Onchocerca volvulus | 0.0068 | 0.0704 | 0.3459 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0323 | 0.1326 |
Echinococcus multilocularis | aldo keto reductase | 0.0068 | 0.0704 | 0.0704 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0038 | 0.0315 | 0.4119 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0224 | 0.2688 | 0.7279 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0038 | 0.0315 | 0.1285 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0195 | 0.0766 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0099 | 0.0077 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0199 | 0.0199 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0038 | 0.0315 | 0.0854 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Brugia malayi | intracellular kinase | 0.016 | 0.1875 | 0.6975 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Schistosoma mansoni | chromobox protein | 0.0069 | 0.0707 | 0.1914 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0055 | 0.0149 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0099 | 0.0077 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0707 | 0.3471 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0038 | 0.0315 | 0.4119 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0145 | 0.0541 |
Echinococcus granulosus | hypothetical protein | 0.0068 | 0.0704 | 0.1907 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.002 | 0.0085 | 0.0327 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0099 | 0.0242 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0079 | 0.0079 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0299 | 0.0811 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.002 | 0.0085 | 0.0166 |
Giardia lamblia | Kinase, CMGC GSK | 0.016 | 0.1875 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0068 | 0.0704 | 0.1907 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0068 | 0.0704 | 0.3673 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0228 | 0.0618 |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0315 | 0.1174 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0068 | 0.0704 | 0.262 |
Loa Loa (eye worm) | carboxylesterase | 0.0038 | 0.0315 | 0.0854 |
Brugia malayi | Carboxylesterase family protein | 0.0038 | 0.0315 | 0.1174 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0315 | 0.0854 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0099 | 0.0099 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0315 | 0.0854 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0055 | 0.5 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0195 | 0.0527 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Onchocerca volvulus | 0.003 | 0.0217 | 0.0735 | |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0038 | 0.0315 | 0.0854 |
Schistosoma mansoni | aldo-keto reductase | 0.0068 | 0.0704 | 0.1907 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0276 | 0.0276 |
Echinococcus multilocularis | aldehyde reductase | 0.0049 | 0.0452 | 0.0452 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.072 | 0.1949 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0195 | 0.0527 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.016 | 0.1875 | 0.1875 |
Echinococcus granulosus | aldehyde reductase | 0.0049 | 0.0452 | 0.1224 |
Echinococcus multilocularis | aldo keto reductase | 0.0068 | 0.0704 | 0.0704 |
Loa Loa (eye worm) | carboxylesterase | 0.0038 | 0.0315 | 0.0854 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Echinococcus multilocularis | snurportin 1 | 0.0303 | 0.3692 | 0.3692 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0314 | 0.0851 |
Trypanosoma brucei | prostaglandin f synthase | 0.0068 | 0.0704 | 0.3673 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0195 | 0.0766 |
Echinococcus multilocularis | acetylcholinesterase | 0.0224 | 0.2688 | 0.2688 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0303 | 0.3692 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.016 | 0.1875 | 1 |
Onchocerca volvulus | 0.0068 | 0.0704 | 0.3459 | |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.2688 | 0.7279 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0099 | 0.0401 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0099 | 0.0269 |
Echinococcus granulosus | carboxylesterase 5A | 0.0224 | 0.2688 | 0.7279 |
Schistosoma mansoni | aldo-keto reductase | 0.0068 | 0.0704 | 0.1907 |
Mycobacterium ulcerans | oxidoreductase | 0.0068 | 0.0704 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0224 | 0.2688 | 1 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0047 | 0.0127 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0199 | 0.0739 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Trichomonas vaginalis | chromobox protein, putative | 0.0069 | 0.0707 | 0.3471 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.103 | 0.3833 |
Echinococcus multilocularis | acetylcholinesterase | 0.0224 | 0.2688 | 0.2688 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0299 | 0.0811 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.002 | 0.0085 | 0.0231 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0099 | 0.0401 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.002 | 0.0085 | 0.0231 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.018 | 0.0527 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0284 | 0.0284 |
Onchocerca volvulus | 0.0038 | 0.0315 | 0.1285 | |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.2688 | 0.7279 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0068 | 0.0704 | 0.3459 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.036 | 0.1534 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.103 | 0.103 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0315 | 0.1174 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0195 | 0.061 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.103 | 0.279 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0047 | 0.0127 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0099 | 0.0401 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0323 | 0.1326 |
Mycobacterium ulcerans | hypothetical protein | 0.002 | 0.0085 | 0.0466 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.002 | 0.0085 | 0.0327 |
Echinococcus granulosus | chromobox protein 1 | 0.0069 | 0.0707 | 0.1914 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0195 | 0.0917 |
Onchocerca volvulus | 0.0068 | 0.0704 | 0.3459 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Entamoeba histolytica | protein kinase, putative | 0.016 | 0.1875 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Brugia malayi | Carboxylesterase family protein | 0.0224 | 0.2688 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0315 | 0.0854 |
Brugia malayi | NADH-dependent xylose reductase | 0.002 | 0.0085 | 0.0318 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0126 | 0.0228 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0407 | 0.0407 |
Entamoeba histolytica | aldose reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.013 | 0.1158 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.013 | 0.0485 |
Onchocerca volvulus | 0.0068 | 0.0704 | 0.3459 | |
Onchocerca volvulus | 0.0038 | 0.0315 | 0.1285 | |
Onchocerca volvulus | 0.0038 | 0.0315 | 0.1285 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.013 | 0.1158 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0224 | 0.2688 | 0.7279 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0224 | 0.2688 | 0.2688 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0017 | 0.0047 | 0.0127 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0068 | 0.0704 | 0.3673 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0017 | 0.0047 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0323 | 0.0874 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.016 | 0.1875 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0068 | 0.0704 | 0.0704 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0199 | 0.0538 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3673 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.013 | 0.1158 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0407 | 0.1101 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0038 | 0.0315 | 0.0854 |
Echinococcus granulosus | protein kinase shaggy | 0.016 | 0.1875 | 0.5077 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0342 | 0.0342 |
Trypanosoma brucei | protein kinase, putative | 0.016 | 0.1875 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0199 | 0.0538 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.013 | 0.0725 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.016 | 0.1875 | 0.5077 |
Entamoeba histolytica | protein kinase domain containing protein | 0.016 | 0.1875 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0017 | 0.0047 | 0.0047 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.018 | 0.0527 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0199 | 0.0538 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.013 | 0.0251 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.0861 | 0.3204 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0068 | 0.0704 | 1 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.002 | 0.0085 | 0.0231 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0068 | 0.0704 | 0.3459 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0092 | 0.0249 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0038 | 0.0315 | 0.1285 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0038 | 0.0315 | 0.0315 |
Echinococcus granulosus | snurportin 1 | 0.0303 | 0.3692 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0299 | 0.0811 |
Brugia malayi | Bromodomain containing protein | 0.0074 | 0.0773 | 0.2878 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0068 | 0.0704 | 0.262 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0038 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0055 | 0.0149 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0038 | 0.0315 | 0.4009 |
Loa Loa (eye worm) | oxidoreductase | 0.0068 | 0.0704 | 0.1907 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0116 | 0.0116 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0344 | 0.0931 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0068 | 0.0704 | 0.0704 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.0582 | 0.0582 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0047 | 0.0127 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.016 | 0.1875 | 1 |
Echinococcus granulosus | neuroligin | 0.0038 | 0.0315 | 0.0854 |
Schistosoma mansoni | potassium channel beta | 0.002 | 0.0085 | 0.0231 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.002 | 0.0085 | 0.0166 |
Schistosoma mansoni | ran | 0.0021 | 0.0099 | 0.0269 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0368 | 0.0996 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0092 | 0.0249 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0126 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0704 | 0.1907 |
Onchocerca volvulus | 0.016 | 0.1875 | 1 | |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0055 | 0.0183 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0055 | 0.0149 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0116 | 0.0313 |
Brugia malayi | Heterochromatin protein 1 | 0.0069 | 0.0707 | 0.2629 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0217 | 0.0588 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0195 | 0.0724 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0059 | 0.0588 | 0.1592 |
Onchocerca volvulus | 0.0068 | 0.0704 | 0.3459 | |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0195 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0055 | 0.0149 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0116 | 0.0313 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0068 | 0.0704 | 0.3459 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0313 | 0.1166 |
Loa Loa (eye worm) | oxidoreductase | 0.0068 | 0.0704 | 0.1907 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.0626 | 0.1697 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0323 | 0.1326 |
Echinococcus multilocularis | chromobox protein 1 | 0.0069 | 0.0707 | 0.0707 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.013 | 0.1158 |
Schistosoma mansoni | pol-related | 0.0068 | 0.0704 | 0.1907 |
Loa Loa (eye worm) | carboxylesterase | 0.0224 | 0.2688 | 0.7279 |
Trichomonas vaginalis | CMGC family protein kinase | 0.016 | 0.1875 | 1 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.002 | 0.0085 | 0.0327 |
Onchocerca volvulus | 0.0038 | 0.0315 | 0.1285 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0407 | 0.1101 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0099 | 0.0077 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0299 | 0.0811 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.013 | 0.132 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0099 | 0.0401 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.013 | 0.0251 |
Giardia lamblia | Aldose reductase | 0.0068 | 0.0704 | 0.3408 |
Echinococcus granulosus | aldo keto reductase | 0.0068 | 0.0704 | 0.1907 |
Loa Loa (eye worm) | oxidoreductase | 0.0068 | 0.0704 | 0.1907 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0099 | 0.0242 |
Echinococcus granulosus | aldo keto reductase | 0.0068 | 0.0704 | 0.1907 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0407 | 0.1101 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.013 | 0.1158 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0068 | 0.0704 | 0.1907 |
Schistosoma mansoni | gliotactin | 0.0038 | 0.0315 | 0.0854 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.013 | 0.057 |
Echinococcus granulosus | acetylcholinesterase | 0.0224 | 0.2688 | 0.7279 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.013 | 0.0353 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0025 | 0.0067 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.016 | 0.1875 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.013 | 0.0485 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 1.6 uM | Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay | ChEMBL. | 21296579 |
ED50 (functional) | = 1.9 uM | Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay | ChEMBL. | 21296579 |
ED50 (functional) | = 2 uM | Antiproliferative activity against human 1A9 cells after 3 days by sulforhodamine B assay | ChEMBL. | 21296579 |
ED50 (functional) | = 2.6 uM | Antiproliferative activity against human HCT8 cells after 3 days by sulforhodamine B assay | ChEMBL. | 21296579 |
ED50 (functional) | = 2.7 uM | Antiproliferative activity against human KB cells after 3 days by sulforhodamine B assay | ChEMBL. | 21296579 |
ED50 (functional) | = 8.3 uM | Antiproliferative activity against human HepG2 cells after 3 days by sulforhodamine B assay | ChEMBL. | 21296579 |
ED50 (functional) | = 8.6 uM | Antiproliferative activity against human PC3 cells after 3 days by sulforhodamine B assay | ChEMBL. | 21296579 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.