Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0033 | 0.0062 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0259 | 0.0614 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0335 | 0.0823 | 0.1539 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0259 | 0.0614 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0033 | 0.0062 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0335 | 0.0823 | 0.1539 |
Echinococcus multilocularis | acetylcholinesterase | 0.1983 | 0.535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Echinococcus multilocularis | acetylcholinesterase | 0.1983 | 0.535 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0259 | 0.0614 | 0.5 |
Onchocerca volvulus | 0.0335 | 0.0823 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.0614 | 0.1148 |
Loa Loa (eye worm) | carboxylesterase | 0.0335 | 0.0823 | 0.1539 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0335 | 0.0823 | 0.1486 |
Onchocerca volvulus | 0.0335 | 0.0823 | 1 | |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0259 | 0.0614 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.1983 | 0.535 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0335 | 0.0823 | 0.1539 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0045 | 0.0084 |
Plasmodium vivax | hypothetical protein, conserved | 0.0259 | 0.0614 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.0614 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.1983 | 0.535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1983 | 0.535 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1983 | 0.535 | 1 |
Onchocerca volvulus | 0.0335 | 0.0823 | 1 | |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0259 | 0.0614 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0335 | 0.0823 | 0.1486 |
Echinococcus granulosus | acetylcholinesterase | 0.1983 | 0.535 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.1983 | 0.535 | 1 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0259 | 0.0614 | 0.5 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0259 | 0.0614 | 0.5 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0259 | 0.0614 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.0614 | 0.1148 |
Brugia malayi | hypothetical protein | 0.0259 | 0.0614 | 0.1148 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0033 | 0.0062 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0259 | 0.0614 | 0.1093 |
Brugia malayi | Carboxylesterase family protein | 0.0335 | 0.0823 | 0.1539 |
Loa Loa (eye worm) | carboxylesterase | 0.0335 | 0.0823 | 0.1539 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0259 | 0.0614 | 0.1093 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0335 | 0.0823 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1983 | 0.535 | 1 |
Brugia malayi | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0335 | 0.0823 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Echinococcus granulosus | carboxylesterase 5A | 0.1983 | 0.535 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0335 | 0.0823 | 0.1486 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0335 | 0.0823 | 0.0223 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0335 | 0.0823 | 0.1486 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0259 | 0.0614 | 0.1093 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0259 | 0.0614 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.0614 | 0.1148 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0259 | 0.0614 | 0.1093 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0335 | 0.0823 | 0.1486 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0335 | 0.0823 | 0.1539 |
Echinococcus granulosus | neuroligin | 0.0335 | 0.0823 | 0.1486 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1983 | 0.535 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0033 | 0.0062 |
Brugia malayi | SWIRM domain containing protein | 0.0259 | 0.0614 | 0.1148 |
Echinococcus multilocularis | 0.0259 | 0.0614 | 0.1093 | |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0259 | 0.0614 | 0.1148 |
Plasmodium vivax | hypothetical protein, conserved | 0.0259 | 0.0614 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0335 | 0.0823 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0335 | 0.0823 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0045 | 0.0084 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0259 | 0.0614 | 0.5 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0259 | 0.0614 | 0.1148 |
Echinococcus multilocularis | neuroligin | 0.0335 | 0.0823 | 0.1486 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0259 | 0.0614 | 0.5 |
Schistosoma mansoni | amine oxidase | 0.0259 | 0.0614 | 0.1148 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0045 | 0.0084 |
Brugia malayi | Carboxylesterase family protein | 0.0335 | 0.0823 | 0.1539 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0335 | 0.0823 | 0.1486 |
Loa Loa (eye worm) | carboxylesterase | 0.1983 | 0.535 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1983 | 0.535 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0335 | 0.0823 | 0.0241 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0033 | 0.0062 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0259 | 0.0614 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0335 | 0.0823 | 0.1539 |
Onchocerca volvulus | 0.0335 | 0.0823 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.0614 | 0.1148 |
Brugia malayi | Carboxylesterase family protein | 0.0335 | 0.0823 | 0.1539 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0335 | 0.0823 | 0.1539 |
Schistosoma mansoni | acetylcholinesterase | 0.0335 | 0.0823 | 0.1539 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0259 | 0.0614 | 0.1148 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.3416 | 0.9289 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0335 | 0.0823 | 0.1539 |
Schistosoma mansoni | amine oxidase | 0.0259 | 0.0614 | 0.1148 |
Onchocerca volvulus | 0.0335 | 0.0823 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.0823 | 0.1539 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0045 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0259 | 0.0614 | 0.1148 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.