Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0037 | 0.0143 | 0.0143 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0037 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Trypanosoma brucei | ATP-dependent protease subunit HslV | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0137 | 0.1421 | 0.4693 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0204 | 0.228 | 0.7528 |
Plasmodium falciparum | proteasome subunit alpha type-3, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0037 | 0.0143 | 0.0358 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0037 | 0.0143 | 0.0143 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0037 | 0.0143 | 0.0358 |
Giardia lamblia | Proteasome subunit beta type 3 | 0.0052 | 0.0333 | 0.0176 |
Echinococcus granulosus | proteasome subunit beta t family | 0.0052 | 0.0333 | 0.0333 |
Plasmodium falciparum | proteasome subunit beta type-7, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0066 | 0.0513 | 0.1695 |
Brugia malayi | Proteasome subunit alpha type 1 | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0037 | 0.0143 | 0.0472 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0204 | 0.228 | 0.7528 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0052 | 0.0333 | 0.0333 |
Giardia lamblia | 20S proteasome alpha subunit 2 | 0.0052 | 0.0333 | 0.0176 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0037 | 0.0143 | 0.0472 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0204 | 0.228 | 0.228 |
Onchocerca volvulus | Matrilysin homolog | 0.0094 | 0.087 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Brugia malayi | proteasome subunit alpha type 2 | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0037 | 0.0143 | 0.0472 |
Leishmania major | proteasome beta-1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0263 | 0.3029 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | proteasome subunit alpha 7 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0263 | 0.3029 | 1 |
Onchocerca volvulus | 0.0037 | 0.0143 | 0.1645 | |
Mycobacterium ulcerans | proteasome PrcA | 0.0052 | 0.0333 | 0.0008 |
Leishmania major | proteasome beta 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0204 | 0.228 | 0.7528 |
Echinococcus granulosus | proteasome prosome macropain subunit beta type | 0.0052 | 0.0333 | 0.0333 |
Plasmodium falciparum | proteasome subunit beta type-6, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | death domain containing protein | 0.0066 | 0.0513 | 0.0513 |
Leishmania major | proteasome beta 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Plasmodium vivax | ATP-dependent protease subunit ClpQ, putative | 0.0052 | 0.0333 | 0.1098 |
Giardia lamblia | Proteasome subunit beta type 9 precursor | 0.0052 | 0.0333 | 0.0176 |
Brugia malayi | Matrixin family protein | 0.0042 | 0.0213 | 0.0703 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0263 | 0.3029 | 1 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | proteasome subunit alpha 6 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0066 | 0.0513 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0518 | 0.1297 |
Brugia malayi | Hemopexin family protein | 0.006 | 0.0438 | 0.1447 |
Plasmodium falciparum | proteasome subunit alpha type-4, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.1421 | 0.3556 |
Echinococcus granulosus | nAChR subunit | 0.0037 | 0.0143 | 0.0143 |
Plasmodium falciparum | ATP-dependent protease subunit ClpQ | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Matrixin family protein | 0.0042 | 0.0213 | 0.0703 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0126 | 0.1289 | 0.4254 |
Leishmania major | hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0048 | 0.0284 | 0.0938 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0037 | 0.0143 | 0.0143 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0066 | 0.0518 | 0.1712 |
Onchocerca volvulus | Netrin receptor homolog | 0.0066 | 0.0513 | 0.5901 |
Plasmodium vivax | proteasome subunit alpha type-3, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0126 | 0.1289 | 0.4254 |
Echinococcus granulosus | proteasome subunit alpha type 2 | 0.0052 | 0.0333 | 0.0333 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0204 | 0.228 | 0.7528 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0048 | 0.0284 | 0.0938 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0037 | 0.0143 | 0.0143 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0037 | 0.0143 | 0.0143 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0143 | 0.0472 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0037 | 0.0143 | 0.0472 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0263 | 0.3029 | 1 |
Plasmodium falciparum | proteasome subunit alpha type-2, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome subunit alpha type-1, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | cathepsin b | 0.0137 | 0.1421 | 0.1421 |
Entamoeba histolytica | proteasome subunit alpha type 5, putative | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0066 | 0.0513 | 0.0513 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0143 | 0.0472 |
Echinococcus multilocularis | cathepsin b | 0.0137 | 0.1421 | 0.1421 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0052 | 0.0333 | 0.0832 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0126 | 0.1289 | 0.4254 |
Onchocerca volvulus | 0.0037 | 0.0143 | 0.1645 | |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0263 | 0.3029 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0037 | 0.0143 | 0.0472 |
Trypanosoma brucei | proteasome beta 2 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Protein kinase domain containing protein | 0.0066 | 0.0513 | 0.1695 |
Mycobacterium ulcerans | proteasome PrcB | 0.0263 | 0.3029 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Brugia malayi | Death domain containing protein | 0.0066 | 0.0513 | 0.1695 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0204 | 0.228 | 0.7528 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0263 | 0.3029 | 1 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0263 | 0.3029 | 1 |
Trypanosoma brucei | proteasome subunit alpha type-5, putative | 0.0052 | 0.0333 | 0.1098 |
Onchocerca volvulus | Matrilysin homolog | 0.0042 | 0.0213 | 0.2446 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0037 | 0.0143 | 0.0472 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0263 | 0.3029 | 0.7578 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0263 | 0.3029 | 1 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0052 | 0.0333 | 0.0832 |
Loa Loa (eye worm) | matrixin family protein | 0.0094 | 0.087 | 0.2177 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Trypanosoma brucei | proteasome beta 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | netrin receptor unc5 | 0.0066 | 0.0513 | 0.1695 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0263 | 0.3029 | 1 |
Giardia lamblia | 20S proteasome alpha subunit 3 | 0.0052 | 0.0333 | 0.0176 |
Trypanosoma brucei | proteasome alpha 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0143 | 0.0472 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0263 | 0.3029 | 1 |
Toxoplasma gondii | proteasome subunit alpha1, putative | 0.0052 | 0.0333 | 0.1098 |
Plasmodium falciparum | proteasome subunit alpha type-6, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0513 | 0.1695 |
Entamoeba histolytica | proteasome subunit alpha type 4, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | proteasome subunit beta type 6 | 0.0052 | 0.0333 | 0.0333 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0048 | 0.0284 | 0.0938 |
Schistosoma mansoni | proteasome catalytic subunit 2 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | LGC-31 protein | 0.0037 | 0.0143 | 0.0358 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0213 | 0.0532 |
Entamoeba histolytica | proteasome subunit beta type 6 precursor, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0126 | 0.1289 | 0.4254 |
Plasmodium vivax | proteasome subunit beta type-4, putative | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | proteasome subunit alpha type 6 | 0.0052 | 0.0333 | 0.0832 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0263 | 0.3029 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0037 | 0.0143 | 0.0143 |
Giardia lamblia | 20S proteasome alpha subunit 6 | 0.0052 | 0.0333 | 0.0176 |
Mycobacterium leprae | probable proteasome (alpha subunit) PrcA | 0.0052 | 0.0333 | 0.0008 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0137 | 0.1421 | 0.4693 |
Trypanosoma brucei | proteasome alpha 7 subunit | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0048 | 0.0284 | 0.0938 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma brucei | proteasome alpha 2 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | Proteasome, subunit alpha beta | 0.0052 | 0.0333 | 0.0333 |
Toxoplasma gondii | proteasome subunit alpha type, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | cathepsin b | 0.0137 | 0.1421 | 0.1421 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0066 | 0.0513 | 0.1695 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0037 | 0.0143 | 0.0472 |
Plasmodium vivax | proteasome subunit beta type-3, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0143 | 0.0472 |
Echinococcus multilocularis | proteasome subunit alpha type 6 | 0.0052 | 0.0333 | 0.0333 |
Echinococcus multilocularis | proteasome subunit beta type 6 | 0.0052 | 0.0333 | 0.0333 |
Plasmodium vivax | proteasome subunit alpha type-5, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | proteasome subunit alpha 3 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0037 | 0.0143 | 0.0143 |
Echinococcus multilocularis | proteasome subunit alpha type 2 | 0.0052 | 0.0333 | 0.0333 |
Entamoeba histolytica | proteasome subunit alpha type 7, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0052 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0154 | 0.1635 | 0.1635 |
Onchocerca volvulus | 0.0037 | 0.0143 | 0.1645 | |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0037 | 0.0143 | 0.0143 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0143 | 0.0472 |
Entamoeba histolytica | proteasome subunit alpha type 5, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | proteasome subunit alpha type 7-1 | 0.0052 | 0.0333 | 0.0832 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0037 | 0.0143 | 0.0143 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0204 | 0.228 | 0.7528 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0037 | 0.0143 | 0.0143 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit alpha | 0.0052 | 0.0333 | 0.0333 |
Schistosoma mansoni | nAChR subunit | 0.0037 | 0.0143 | 0.0472 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0048 | 0.0284 | 0.0938 |
Trypanosoma cruzi | proteasome beta 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | cathepsin b | 0.0137 | 0.1421 | 0.1421 |
Loa Loa (eye worm) | proteasome subunit alpha type 3 | 0.0052 | 0.0333 | 0.0832 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0263 | 0.3029 | 1 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | proteasome alpha 2 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Giardia lamblia | 20S proteasome alpha subunit 7 | 0.0052 | 0.0333 | 0.0176 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0037 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0037 | 0.0143 | 0.0358 |
Echinococcus granulosus | proteasome subunit alpha type 6 | 0.0052 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Toxoplasma gondii | proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | matrixin family protein | 0.0102 | 0.0978 | 0.2447 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0066 | 0.0513 | 0.0513 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0137 | 0.1421 | 0.4693 |
Toxoplasma gondii | peptidase, T1 family protein | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Matrixin family protein | 0.0042 | 0.0213 | 0.0703 |
Echinococcus granulosus | Ankyrin | 0.0066 | 0.0518 | 0.0518 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0037 | 0.0143 | 0.0472 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0066 | 0.0513 | 0.1285 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0037 | 0.0143 | 0.0143 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0037 | 0.0143 | 0.0143 |
Giardia lamblia | 20S proteasome alpha subunit 4 | 0.0052 | 0.0333 | 0.0176 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0037 | 0.0143 | 0.0358 |
Brugia malayi | 20S proteasome alpha5 subunit | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Loa Loa (eye worm) | proteasome subunit beta type 3 | 0.0052 | 0.0333 | 0.0832 |
Loa Loa (eye worm) | proteasome subunit alpha type 1 | 0.0052 | 0.0333 | 0.0832 |
Plasmodium vivax | proteasome subunit alpha type-1, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0126 | 0.1289 | 0.4254 |
Echinococcus granulosus | subfamily T1A non peptidase ue | 0.0052 | 0.0333 | 0.0333 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit beta type | 0.0052 | 0.0333 | 0.0333 |
Trypanosoma brucei | proteasome beta-1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Giardia lamblia | 20S proteasome alpha subunit 1 | 0.0052 | 0.0333 | 0.0176 |
Brugia malayi | proteasome subunit beta type 1 | 0.0204 | 0.228 | 0.7528 |
Toxoplasma gondii | heat shock protein hslv, putative | 0.0052 | 0.0333 | 0.1098 |
Onchocerca volvulus | 0.0037 | 0.0143 | 0.1645 | |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0037 | 0.0143 | 0.0358 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Brugia malayi | proteasome subunit alpha type 3 | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | ATP-dependent protease subunit HslV, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0213 | 0.0532 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0037 | 0.0143 | 0.0143 |
Echinococcus multilocularis | nAChR subunit | 0.0037 | 0.0143 | 0.0143 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0143 | 0.0472 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0263 | 0.3029 | 0.3029 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0263 | 0.3029 | 1 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | 20S proteasome alpha5 subunit | 0.0052 | 0.0333 | 0.0832 |
Echinococcus granulosus | proteasome subunit beta type 7 | 0.0052 | 0.0333 | 0.0333 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0037 | 0.0143 | 0.0472 |
Toxoplasma gondii | proteasome subunit beta type 7 precursor, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0037 | 0.0143 | 0.0472 |
Entamoeba histolytica | proteasome subunit alpha type 2-A, putative | 0.0052 | 0.0333 | 0.1098 |
Toxoplasma gondii | proteasome subunit alpha type 1, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0126 | 0.1289 | 0.4254 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0037 | 0.0143 | 0.0143 |
Trypanosoma cruzi | proteasome beta 2 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | proteasome subunit beta 4 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Toxoplasma gondii | 20S proteasome subunit beta 7, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Uncoordinated protein 44 | 0.0066 | 0.0513 | 0.1695 |
Loa Loa (eye worm) | cathepsin B | 0.0048 | 0.0284 | 0.0711 |
Plasmodium vivax | proteasome subunit alpha type-6, putative | 0.0052 | 0.0333 | 0.1098 |
Entamoeba histolytica | proteasome subunit alpha type 3, putative | 0.0052 | 0.0333 | 0.1098 |
Giardia lamblia | Proteasome subunit beta type 7 precursor | 0.0052 | 0.0333 | 0.0176 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0037 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0037 | 0.0143 | 0.0358 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0204 | 0.228 | 0.7528 |
Plasmodium falciparum | proteasome subunit beta type-3, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0037 | 0.0143 | 0.0472 |
Trypanosoma cruzi | hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B | 0.0052 | 0.0333 | 0.1098 |
Entamoeba histolytica | proteasome subunit alpha type 3, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | proteasome subunit beta type 3 | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0513 | 0.1285 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0263 | 0.3029 | 1 |
Echinococcus multilocularis | Ankyrin | 0.0066 | 0.0518 | 0.0518 |
Brugia malayi | proteasome subunit alpha type 6 | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0126 | 0.1289 | 0.1289 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0143 | 0.0472 |
Brugia malayi | proteasome subunit beta type 2 | 0.0126 | 0.1289 | 0.4254 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | proteasome catalytic subunit 1 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0052 | 0.0333 | 0.5 |
Entamoeba histolytica | proteasome subunit alpha type 4, putative | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Entamoeba histolytica | proteasome subunit alpha type 6, putative | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Entamoeba histolytica | proteasome subunit beta Type 4 precursor, putative | 0.0052 | 0.0333 | 0.1098 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0126 | 0.1289 | 0.4254 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0037 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Plasmodium falciparum | proteasome subunit alpha type-1, putative | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0126 | 0.1289 | 0.4254 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0137 | 0.1421 | 0.4693 |
Plasmodium vivax | proteasome subunit alpha type-4, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma brucei | proteasome alpha 1 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Cation transporter family protein | 0.0037 | 0.0143 | 0.0472 |
Trypanosoma brucei | proteasome alpha 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0204 | 0.228 | 0.7273 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0126 | 0.1289 | 0.3224 |
Giardia lamblia | Proteasome subunit beta type 4 precursor | 0.0052 | 0.0333 | 0.0176 |
Loa Loa (eye worm) | PAS-3 protein | 0.0052 | 0.0333 | 0.0832 |
Entamoeba histolytica | proteasome subunit beta type 3, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0037 | 0.0143 | 0.0472 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Plasmodium falciparum | proteasome subunit beta type-4 | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Proteasome subunit alpha type 7-1 | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0154 | 0.1635 | 0.1635 |
Echinococcus multilocularis | subfamily T1A non peptidase ue | 0.0052 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | proteasome subunit alpha type 2 | 0.0052 | 0.0333 | 0.0832 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0137 | 0.1421 | 0.4693 |
Plasmodium vivax | proteasome subunit alpha type-2, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.3997 | 1 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0066 | 0.0513 | 0.0513 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0052 | 0.0333 | 0.0832 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0052 | 0.0333 | 0.1098 |
Entamoeba histolytica | proteasome subunit beta type 7-B precursor, putative | 0.0052 | 0.0333 | 0.1098 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0094 | 0.087 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0037 | 0.0143 | 0.0472 |
Brugia malayi | Matrixin family protein | 0.0102 | 0.0978 | 0.3229 |
Entamoeba histolytica | proteasome subunit alpha type 7, putative | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | proteasome alpha 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0037 | 0.0143 | 0.0143 |
Echinococcus granulosus | Proteasome subunit alpha type 7 | 0.0052 | 0.0333 | 0.0333 |
Trypanosoma brucei | proteasome beta 7 subunit | 0.0052 | 0.0333 | 0.1098 |
Giardia lamblia | 20S proteasome alpha subunit 5 | 0.0052 | 0.0333 | 0.0176 |
Brugia malayi | Cation transporter family protein | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | proteasome subunit alpha 2 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta | 0.0052 | 0.0333 | 0.0333 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0037 | 0.0143 | 0.0472 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | proteasome subunit alpha 4 (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | proteasome subunit alpha type 1 | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0052 | 0.0333 | 0.1098 |
Toxoplasma gondii | cathepsin B | 0.0048 | 0.0284 | 0.0938 |
Brugia malayi | Cation transporter family protein | 0.0037 | 0.0143 | 0.0472 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0126 | 0.1289 | 0.3659 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0213 | 0.0532 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0037 | 0.0143 | 0.0143 |
Echinococcus granulosus | proteasome prosome macropain subunit alpha | 0.0052 | 0.0333 | 0.0333 |
Plasmodium falciparum | proteasome subunit alpha type-7, putative | 0.0052 | 0.0333 | 0.1098 |
Brugia malayi | proteasome subunit alpha type 4 | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0037 | 0.0143 | 0.0143 |
Onchocerca volvulus | 0.0042 | 0.0213 | 0.2446 | |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0204 | 0.228 | 0.7528 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0042 | 0.0213 | 0.0703 |
Onchocerca volvulus | 0.006 | 0.0438 | 0.5038 | |
Echinococcus granulosus | 20S proteasome subunit alpha 6 | 0.0052 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0126 | 0.1289 | 0.4254 |
Onchocerca volvulus | Notchless protein homolog | 0.0052 | 0.0333 | 0.3822 |
Echinococcus multilocularis | proteasome subunit beta type 7 | 0.0052 | 0.0333 | 0.0333 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.0438 | 0.1447 |
Toxoplasma gondii | proteasome subunit | 0.0052 | 0.0333 | 0.1098 |
Plasmodium vivax | proteasome subunit beta type-7, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.033 | 0.0827 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0052 | 0.0333 | 0.1098 |
Loa Loa (eye worm) | ACC-1 protein | 0.0037 | 0.0143 | 0.0358 |
Trypanosoma brucei | Proteasome subunit A N-terminal signature/Proteasome subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus granulosus | proteasome prosome macropain | 0.0263 | 0.3029 | 0.3029 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0037 | 0.0143 | 0.0472 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0204 | 0.228 | 0.7528 |
Entamoeba histolytica | calcium-dependent protein kinase 2, putative | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Onchocerca volvulus | 0.0037 | 0.0143 | 0.1645 | |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0126 | 0.1289 | 0.1289 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0126 | 0.1289 | 0.4254 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0204 | 0.228 | 0.228 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0037 | 0.0143 | 0.0143 |
Echinococcus multilocularis | 20S proteasome subunit alpha 6 | 0.0052 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Brugia malayi | Matrixin family protein | 0.0042 | 0.0213 | 0.0703 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0037 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0052 | 0.0333 | 0.1098 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0204 | 0.228 | 0.7528 |
Plasmodium vivax | proteasome subunit alpha type-7, putative | 0.0052 | 0.0333 | 0.1098 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0052 | 0.0333 | 0.0333 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0126 | 0.1289 | 0.4254 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0037 | 0.0143 | 0.0472 |
Plasmodium falciparum | proteasome subunit alpha type-5, putative | 0.0052 | 0.0333 | 0.1098 |
Trichomonas vaginalis | Family T1, proteasome alpha subunit, threonine peptidase | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0126 | 0.1289 | 0.4254 |
Echinococcus granulosus | Proteasome subunit alpha beta | 0.0052 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0143 | 0.0358 |
Entamoeba histolytica | proteasome subunit alpha type 1, putative | 0.0052 | 0.0333 | 0.1098 |
Toxoplasma gondii | proteasome subunit alpha type 5-2, putative | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0052 | 0.0333 | 0.1098 |
Toxoplasma gondii | proteasome beta subunit | 0.0052 | 0.0333 | 0.1098 |
Onchocerca volvulus | Putative nachr subunit | 0.0037 | 0.0143 | 0.1645 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0037 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | ACC-1 protein | 0.0037 | 0.0143 | 0.0358 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0052 | 0.0333 | 0.1098 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0052 | 0.0333 | 0.1098 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0137 | 0.1421 | 0.4693 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0042 | 0.0213 | 0.0532 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0204 | 0.228 | 0.5705 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.0052 | 0.0333 | 0.0008 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0037 | 0.0143 | 0.0143 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0051 | 0.033 | 0.1091 |
Plasmodium vivax | proteasome subunit beta type-6, putative | 0.0052 | 0.0333 | 0.1098 |
Onchocerca volvulus | 0.0037 | 0.0143 | 0.1645 | |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0052 | 0.0333 | 0.1098 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 4.73 uM | Cytotoxicity against human SKBR3 cells after 72 hrs by MTT assay | ChEMBL. | 21420855 |
ED50 (functional) | = 5.42 uM | Cytotoxicity against human A549 cells after 72 hrs by MTT assay | ChEMBL. | 21420855 |
ED50 (functional) | = 5.42 uM | Cytotoxicity against human DU145 cells after 72 hrs by MTT assay | ChEMBL. | 21420855 |
ED50 (functional) | = 8.38 uM | Cytotoxicity against human KB cells after 72 hrs by MTT assay | ChEMBL. | 21420855 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.