Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0488 | 0.0488 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0052 | 0.0052 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.07 | 0.0555 |
Onchocerca volvulus | 0.0035 | 0.07 | 0.0223 | |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.07 | 0.07 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.07 | 0.0555 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.1381 | 0.1381 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0766 | 0.0766 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.07 | 0.0555 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.07 | 0.0555 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0104 | 0.315 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0194 | 0.6355 | 0.6336 |
Brugia malayi | Peptidase family M1 containing protein | 0.0104 | 0.315 | 0.315 |
Echinococcus multilocularis | geminin | 0.0194 | 0.6355 | 0.6336 |
Brugia malayi | beta-lactamase | 0.0035 | 0.07 | 0.07 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0104 | 0.315 | 1 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0086 | 0.2507 | 0.2468 |
Brugia malayi | hypothetical protein | 0.027 | 0.9091 | 0.9091 |
Onchocerca volvulus | 0.0104 | 0.315 | 0.2799 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.07 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0488 | 0.0439 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0136 | 0.4311 | 0.4311 |
Onchocerca volvulus | 0.0035 | 0.07 | 0.0223 | |
Echinococcus granulosus | lamin | 0.0029 | 0.0488 | 0.0439 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0488 | 0.0439 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.07 | 0.0555 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.1381 | 0.1381 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.5694 | 0.537 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.1406 | 0.1361 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.07 | 0.07 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0104 | 0.315 | 0.3115 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0488 | 0.0488 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0104 | 0.315 | 0.315 |
Brugia malayi | MH2 domain containing protein | 0.0136 | 0.4311 | 0.4311 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0024 | 0.03 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.07 | 0.0413 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 0.8974 | 0.8896 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.07 | 0.0652 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0104 | 0.315 | 0.2939 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.315 | 0.315 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.5694 | 0.537 |
Schistosoma mansoni | lamin | 0.0029 | 0.0488 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0469 | 0.0469 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.5694 | 0.537 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.07 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0488 | 0.0488 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.6286 | 0.6286 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0104 | 0.315 | 0.3115 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.315 | 0.315 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.5694 | 0.537 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.07 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.07 | 0.07 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0192 | 0.6286 | 0.6006 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0226 | 0.7511 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1381 | 0.1381 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.07 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0488 | 0.0488 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.07 | 0.0555 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0052 | 0.0052 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0104 | 0.315 | 0.2635 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0488 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2507 | 0.2507 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.07 | 0.1404 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0104 | 0.315 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0185 | 0.6031 | 0.5732 |
Onchocerca volvulus | 0.0035 | 0.07 | 0.0223 | |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.3961 | 0.3961 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0104 | 0.315 | 0.3115 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.07 | 0.0413 |
Brugia malayi | TATA binding protein associated factor | 0.0104 | 0.315 | 0.315 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0086 | 0.2507 | 0.2507 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.07 | 0.0555 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.027 | 0.9091 | 0.9086 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.07 | 0.0413 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.07 | 0.0652 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.07 | 0.0413 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0104 | 0.315 | 1 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0104 | 0.315 | 0.3115 |
Trypanosoma brucei | aminopeptidase, putative | 0.0104 | 0.315 | 0.2939 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.5694 | 0.537 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0488 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.6286 | 0.6286 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0086 | 0.2507 | 0.2468 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.07 | 0.0555 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0052 | 0.0052 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0192 | 0.6286 | 0.6267 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0024 | 0.03 | 0.5 |
Schistosoma mansoni | lamin | 0.0029 | 0.0488 | 0.0439 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.07 | 0.0555 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0104 | 0.315 | 0.2939 |
Brugia malayi | hypothetical protein | 0.0127 | 0.3961 | 0.3961 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.07 | 0.0652 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0192 | 0.6286 | 0.6267 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.07 | 0.07 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.1381 | 0.1381 |
Onchocerca volvulus | 0.0086 | 0.2507 | 0.2122 | |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.07 | 0.0413 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0104 | 0.315 | 0.2635 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0104 | 0.315 | 0.3115 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 0.8974 | 0.8896 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0488 | 0.0439 |
Toxoplasma gondii | aminopeptidase N protein | 0.0104 | 0.315 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0766 | 0.0766 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0104 | 0.315 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.07 | 0.0652 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.6286 | 0.6286 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.07 | 0.0555 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.07 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.07 | 0.1404 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 0.8974 | 0.8896 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0267 | 0.8974 | 0.8974 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.027 | 0.9091 | 0.9086 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 0.8974 | 0.8896 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.07 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0104 | 0.315 | 0.2635 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0766 | 0.0718 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0488 | 0.0439 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.3961 | 0.3961 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0253 | 0.8471 | 0.8471 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.315 | 0.315 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0175 | 0.5694 | 0.5473 |
Echinococcus granulosus | geminin | 0.0194 | 0.6355 | 0.6336 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.07 | 0.0413 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0086 | 0.2507 | 0.2468 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0104 | 0.315 | 0.3115 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0104 | 0.315 | 0.3115 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0104 | 0.315 | 0.2939 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0104 | 0.315 | 0.2635 |
Onchocerca volvulus | 0.0055 | 0.1406 | 0.0964 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0052 | 0.0052 |
Brugia malayi | hypothetical protein | 0.0104 | 0.315 | 0.315 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0185 | 0.6031 | 0.5732 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.3961 | 0.3651 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0104 | 0.315 | 0.2635 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.07 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0194 | 0.6355 | 0.6336 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0488 | 0.0488 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 0.8974 | 0.8896 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.07 | 0.07 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.07 | 0.0413 |
Brugia malayi | follicle stimulating hormone receptor | 0.0253 | 0.8471 | 0.8471 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0267 | 0.8974 | 0.8896 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.5694 | 0.537 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0055 | 0.1406 | 0.1406 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0024 | 0.03 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.9091 | 0.9091 |
Schistosoma mansoni | survival motor neuron protein | 0.0055 | 0.1406 | 0.1361 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0104 | 0.315 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0175 | 0.5694 | 0.537 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0267 | 0.8974 | 0.8974 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0104 | 0.315 | 0.2635 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.07 | 0.07 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.3961 | 0.3651 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0136 | 0.4311 | 0.4311 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0104 | 0.315 | 0.315 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0104 | 0.315 | 0.315 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.