Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0022 | 0.0052 | 0.0052 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0186 | 0.0169 |
Brugia malayi | nuclear hormone receptor | 0.0022 | 0.0052 | 0.0051 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0236 | 0.1435 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. | 0.0085 | 0.046 | 0.1613 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0106 | 0.0597 | 0.0597 |
Echinococcus granulosus | peregrin | 0.0035 | 0.0133 | 0.0133 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0158 | 0.042 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0055 | 0.0054 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0139 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0225 | 0.0224 |
Mycobacterium ulcerans | dehydratase | 0.0085 | 0.046 | 0.1416 |
Echinococcus multilocularis | zinc finger protein | 0.0024 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | glutaminase 2 | 0.0303 | 0.187 | 0.1869 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0052 | 0.0052 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0018 | 0.002 | 0.0013 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0052 | 0.0052 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0022 | 0.0052 | 0.0035 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0106 | 0.0597 | 0.0581 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0034 | 0.0124 | 0.0382 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0022 | 0.0052 | 0.0035 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0032 | 0.0116 | 0.01 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0052 | 0.0051 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0106 | 0.0597 | 0.0597 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0126 | 0.0126 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.002 | 0.0019 |
Onchocerca volvulus | 0.0263 | 0.1612 | 0.1568 | |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0018 | 0.002 | 0.002 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0022 | 0.0052 | 0.0052 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0027 | 0.0083 | 0.0229 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0186 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0415 | 0.0414 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0043 | 0.0187 | 0.0186 |
Schistosoma mansoni | thyroid hormone receptor | 0.0022 | 0.0052 | 0.0035 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0098 | 0.0097 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0052 | 0.0051 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0236 | 0.1435 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0139 | 0.0122 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0022 | 0.0052 | 0.0051 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.002 | 0.002 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0043 | 0.0186 | 0.0186 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0106 | 0.0597 | 0.0597 |
Schistosoma mansoni | bromodomain containing protein | 0.0072 | 0.0373 | 0.0357 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0032 | 0.0116 | 0.0352 |
Echinococcus multilocularis | amyloid beta A4 protein | 0.0076 | 0.04 | 0.04 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0139 | 0.0122 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0106 | 0.0597 | 0.0597 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0022 | 0.0051 | 0.0051 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0106 | 0.0597 | 0.0597 |
Onchocerca volvulus | 0.0034 | 0.0126 | 0.0074 | |
Schistosoma mansoni | zinc finger protein | 0.0024 | 0.0059 | 0.0043 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0067 | 0.0339 | 0.0338 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0037 | 0.0145 | 0.0144 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0438 | 0.2746 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0043 | 0.0186 | 0.0185 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0126 | 0.0387 |
Echinococcus granulosus | FTZ F1 alpha | 0.0022 | 0.0052 | 0.0052 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0052 | 0.0052 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0039 | 0.0158 | 0.0517 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0043 | 0.0187 | 0.061 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0022 | 0.0052 | 0.0052 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0116 | 0.01 |
Brugia malayi | ecdysteroid receptor | 0.0022 | 0.0052 | 0.0051 |
Onchocerca volvulus | 0.0032 | 0.0113 | 0.0061 | |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0027 | 0.0083 | 0.0242 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.002 | 0.0003 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0081 | 0.0081 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0052 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0116 | 0.0115 |
Toxoplasma gondii | NAC domain-containing protein | 0.0039 | 0.0158 | 0.0505 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.002 | 0.002 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0022 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0132 | 0.0764 | 0.0763 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.002 | 0.002 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0045 | 0.0198 | 0.0198 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0039 | 0.0158 | 0.0996 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.002 | 0.0019 |
Mycobacterium ulcerans | hypothetical protein | 0.0085 | 0.046 | 0.1416 |
Brugia malayi | nuclear receptor NHR-88 | 0.0022 | 0.0052 | 0.0051 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0182 | 0.0182 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0347 | 0.0347 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0027 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0265 | 0.0264 |
Schistosoma mansoni | glutaminase | 0.0303 | 0.187 | 0.1856 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0027 | 0.0083 | 0.0083 |
Brugia malayi | Bromodomain containing protein | 0.0085 | 0.0457 | 0.0456 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0236 | 0.1435 | 0.5195 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0022 | 0.0052 | 0.0035 |
Loa Loa (eye worm) | SCP-2 sterol transfer family protein | 0.0033 | 0.0124 | 0.0123 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0032 | 0.0116 | 0.0116 |
Mycobacterium ulcerans | transcriptional regulator | 0.0033 | 0.0124 | 0.0153 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0052 | 0.0051 |
Onchocerca volvulus | 0.0037 | 0.0145 | 0.0094 | |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0124 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0199 | 0.0199 |
Plasmodium vivax | hypothetical protein, conserved | 0.0032 | 0.0116 | 0.0352 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0024 | 0.006 | 0.0059 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0106 | 0.0597 | 0.0597 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0052 | 0.0051 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0052 | 0.0051 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0029 | 0.0013 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0032 | 0.0116 | 0.0115 |
Brugia malayi | maoC like domain containing protein | 0.0085 | 0.046 | 0.0459 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0106 | 0.0593 | 0.0593 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.046 | 0.0459 |
Echinococcus granulosus | transcription factor btf3 | 0.0039 | 0.0158 | 0.0158 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0158 | 0.042 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0052 | 0.0052 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0126 | 0.0109 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0132 | 0.0764 | 0.0763 |
Schistosoma mansoni | jumonji domain containing protein | 0.0084 | 0.0452 | 0.0436 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0126 | 0.0109 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0052 | 0.0035 |
Mycobacterium tuberculosis | Conserved protein | 0.0034 | 0.0124 | 0.0382 |
Mycobacterium ulcerans | (3R)-hydroxyacyl-ACP dehydratase subunit HadA | 0.0034 | 0.0124 | 0.0156 |
Echinococcus granulosus | amyloid beta A4 protein | 0.0076 | 0.04 | 0.04 |
Schistosoma mansoni | transcription factor btf3 | 0.0039 | 0.0158 | 0.0141 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0284 | 0.1747 | 0.1746 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.002 | 0.0034 | 0.0018 |
Leishmania major | basic transcription factor 3a, putative | 0.0039 | 0.0158 | 0.0517 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0039 | 0.0158 | 0.0996 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0051 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.002 | 0.0003 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0022 | 0.0052 | 0.0052 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0032 | 0.0116 | 0.0116 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0022 | 0.0052 | 0.0051 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0022 | 0.0052 | 0.0052 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0027 | 0.0083 | 0.0466 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0152 | 0.0135 |
Brugia malayi | beta-NAC-like protein | 0.0039 | 0.0158 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0052 | 0.0051 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0045 | 0.02 | 0.02 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0052 | 0.0051 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0019 | 0.0029 | 0.0013 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0022 | 0.0052 | 0.0051 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0438 | 0.2746 | 1 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0438 | 0.2746 | 1 |
Brugia malayi | SCP-2 sterol transfer family protein | 0.0033 | 0.0124 | 0.0123 |
Onchocerca volvulus | Alhambra homolog | 0.0032 | 0.0116 | 0.0065 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0022 | 0.0052 | 0.0051 |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0077 | 0.0403 | 0.1405 |
Toxoplasma gondii | hypothetical protein | 0.002 | 0.0034 | 0.005 |
Schistosoma mansoni | coup transcription factor | 0.0022 | 0.0052 | 0.0035 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.002 | 0.0019 |
Brugia malayi | abnormal cell lineage protein 10 (Protein lin-10), putative | 0.0068 | 0.0348 | 0.0347 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.0158 | 0.042 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0106 | 0.0597 | 0.0597 |
Brugia malayi | sterol carrier protein | 0.0033 | 0.0124 | 0.0123 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0133 | 0.0132 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0022 | 0.0052 | 0.0051 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0124 | 0.0156 |
Brugia malayi | MH2 domain containing protein | 0.0132 | 0.0764 | 0.0763 |
Echinococcus granulosus | zinc finger protein | 0.0024 | 0.0059 | 0.0059 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.002 | 0.0003 |
Giardia lamblia | PHD finger protein 15 | 0.0032 | 0.0116 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0152 | 0.0151 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.0182 | 0.0181 |
Schistosoma mansoni | amyloid beta A4 protein related | 0.0076 | 0.04 | 0.0384 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0053 | 0.0248 | 0.0232 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.002 | 0.0013 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0438 | 0.2746 | 1 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0027 | 0.0083 | 0.0466 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0106 | 0.0597 | 0.0597 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0052 | 0.0052 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0152 | 0.0151 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0032 | 0.0116 | 0.0352 |
Mycobacterium tuberculosis | Conserved protein | 0.0027 | 0.0083 | 0.0229 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0065 | 0.0327 | 0.2186 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0265 | 0.0264 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0113 | 0.0113 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.0034 | 0.0033 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0106 | 0.0597 | 0.0597 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0043 | 0.0187 | 0.039 |
Brugia malayi | PHD-finger family protein | 0.0032 | 0.0116 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0034 | 0.0033 |
Brugia malayi | glutaminase DH11.1 | 0.0303 | 0.187 | 0.1869 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | glutaminase | 0.0303 | 0.187 | 0.1869 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0019 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0034 | 0.0033 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0265 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0124 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.002 | 0.0003 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0018 | 0.002 | 0.0004 |
Toxoplasma gondii | MaoC family domain-containing protein | 0.0052 | 0.0243 | 0.0815 |
Echinococcus multilocularis | sodium channel protein | 0.0045 | 0.02 | 0.02 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0039 | 0.0158 | 0.0505 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0043 | 0.0187 | 0.039 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.002 | 0.002 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0043 | 0.0187 | 0.0186 |
Schistosoma mansoni | voltage-gated cation channel | 0.0106 | 0.0597 | 0.0581 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0052 | 0.0051 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0124 | 0.0156 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0052 | 0.0052 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0018 | 0.002 | 0.0025 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0113 | 0.0097 |
Mycobacterium tuberculosis | Probable 3-hydroxyacyl-thioester dehydratase HtdY | 0.0085 | 0.046 | 0.1613 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.002 | 0.0013 |
Loa Loa (eye worm) | oxidoreductase | 0.0037 | 0.0145 | 0.0144 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0438 | 0.2746 | 0.5 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0022 | 0.0052 | 0.0051 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0126 | 0.0387 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Plasmodium falciparum | phd finger protein, putative | 0.0032 | 0.0116 | 0.0352 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0165 | 0.0165 |
Mycobacterium ulcerans | (3R)-hydroxyacyl-ACP dehydratase subunit HadC | 0.0034 | 0.0124 | 0.0156 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0018 | 0.002 | 0.0025 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0106 | 0.0597 | 0.0596 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0022 | 0.0052 | 0.0035 |
Brugia malayi | steroid hormone receptor | 0.0022 | 0.0052 | 0.0051 |
Mycobacterium ulcerans | hypothetical protein | 0.0034 | 0.0124 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0248 | 0.0247 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0106 | 0.0593 | 0.0593 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0022 | 0.0051 | 0.0114 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0053 | 0.0248 | 0.0248 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0069 | 0.0352 | 0.0336 |
Brugia malayi | Pre-SET motif family protein | 0.0231 | 0.1406 | 0.1405 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0039 | 0.0158 | 0.0505 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0022 | 0.0052 | 0.0035 |
Brugia malayi | jmjC domain containing protein | 0.0106 | 0.0593 | 0.0592 |
Loa Loa (eye worm) | X11 protein | 0.0076 | 0.04 | 0.0399 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0022 | 0.0052 | 0.0051 |
Brugia malayi | Isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0051 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0022 | 0.0052 | 0.0051 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0022 | 0.0052 | 0.0052 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0438 | 0.2746 | 1 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0065 | 0.0327 | 0.1136 |
Mycobacterium ulcerans | hypothetical protein | 0.0033 | 0.0124 | 0.0153 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0106 | 0.0597 | 0.0581 |
Brugia malayi | CXXC zinc finger family protein | 0.0032 | 0.0113 | 0.0112 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.002 | 0.002 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0039 | 0.016 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0597 | 0.0596 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0106 | 0.0597 | 0.0597 |
Entamoeba histolytica | hypothetical protein | 0.0438 | 0.2746 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0052 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.002 | 0.0019 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0438 | 0.2746 | 0.5 |
Brugia malayi | isocitrate dehydrogenase | 0.0018 | 0.002 | 0.002 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0438 | 0.2746 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0381 | 0.038 |
Echinococcus multilocularis | transcription factor btf3 | 0.0039 | 0.0158 | 0.0158 |
Trichomonas vaginalis | glutaminase, putative | 0.0303 | 0.187 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0022 | 0.0052 | 0.0052 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0053 | 0.0248 | 0.0248 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0438 | 0.2746 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0438 | 0.2746 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0236 | 0.1435 | 0.5195 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0053 | 0.0248 | 0.0232 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0022 | 0.0052 | 0.0035 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0019 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0284 | 0.1747 | 0.1746 |
Loa Loa (eye worm) | calcium channel | 0.0106 | 0.0597 | 0.0596 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0231 | 0.1406 | 0.1405 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0032 | 0.0113 | 0.0112 |
Trichomonas vaginalis | set domain proteins, putative | 0.0263 | 0.1612 | 0.8559 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0022 | 0.0052 | 0.0035 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0381 | 0.038 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0165 | 0.0165 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0022 | 0.0052 | 0.0051 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0126 | 0.0125 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0022 | 0.0052 | 0.0051 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0265 | 0.0264 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0081 | 0.0064 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0139 | 0.0139 |
Mycobacterium ulcerans | glutaminase | 0.0303 | 0.187 | 0.6711 |
Loa Loa (eye worm) | ICD-1 protein | 0.0039 | 0.0158 | 0.0157 |
Schistosoma mansoni | thyroid hormone receptor | 0.0022 | 0.0052 | 0.0035 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0068 | 0.0347 | 0.0347 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0055 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0022 | 0.0052 | 0.0051 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0022 | 0.0052 | 0.0051 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0438 | 0.2746 | 1 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0438 | 0.2746 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0266 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0052 | 0.0051 |
Echinococcus granulosus | jumonji domain containing protein | 0.0045 | 0.0198 | 0.0198 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0438 | 0.2746 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0081 | 0.0081 |
Mycobacterium tuberculosis | (3R)-hydroxyacyl-ACP dehydratase subunit HadC | 0.0034 | 0.0124 | 0.0382 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0022 | 0.0052 | 0.0035 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.002 | 0.002 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0043 | 0.0186 | 0.0185 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.0323 | 0.1109 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0022 | 0.0051 | 0.0051 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 3 % | Inhibition of HDAC in human HeLa cells at 10 uM by fluorescent activity assay | ChEMBL. | 21420859 |
Inhibition (binding) | = 10 % | Inhibition of HDAC in human HeLa cells at 50 uM by fluorescent activity assay | ChEMBL. | 21420859 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.