Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0037 | 0.0033 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0018 | 0.0015 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0095 | 0.0174 | 0.017 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.1365 | 0.2796 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0055 | 0.0052 |
Brugia malayi | maoC like domain containing protein | 0.0167 | 0.0322 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0009 | 0.0006 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0024 | 0.0027 | 0.0064 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0043 | 0.004 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0018 | 0.0015 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0012 | 0.0008 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0095 | 0.0174 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0013 | 0.0009 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0048 | 0.042 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0018 | 0.0015 |
Mycobacterium ulcerans | (3R)-hydroxyacyl-ACP dehydratase subunit HadC | 0.0066 | 0.0112 | 0.0314 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0018 | 0.0015 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0037 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0079 | 0.0075 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0018 | 0.0015 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0048 | 0.042 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0048 | 0.0996 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0015 |
Mycobacterium ulcerans | (3R)-hydroxyacyl-ACP dehydratase subunit HadA | 0.0066 | 0.0112 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0014 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0039 | 0.0031 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.0536 | 0.0529 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0018 | 0.0015 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.0536 | 0.0533 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0009 | 0.0025 |
Mycobacterium ulcerans | hypothetical protein | 0.0066 | 0.0112 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0074 | 0.0071 |
Brugia malayi | hypothetical protein | 0.0065 | 0.0112 | 0.0108 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0018 | 0.0015 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0009 | 0.0025 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0102 | 0.0099 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0058 | 0.0097 | 0.0317 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0041 | 0.0038 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0024 | 0.0027 | 0.0466 |
Trypanosoma brucei | hypothetical protein, conserved | 0.1365 | 0.2796 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0038 | 0.0056 | 0.0053 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0018 | 0.0015 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0095 | 0.0174 | 0.017 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0009 | 0.0006 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0037 | 0.0028 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0031 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0079 | 0.0076 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0066 | 0.0112 | 0.037 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0084 | 0.0151 | 0.0454 |
Toxoplasma gondii | hypothetical protein | 0.0018 | 0.0013 | 0.0014 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0095 | 0.0174 | 0.017 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0018 | 0.0015 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0102 | 0.0099 |
Schistosoma mansoni | amyloid beta A4 protein related | 0.0068 | 0.0117 | 0.0109 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0001 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0037 | 0.0033 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Mycobacterium leprae | conserved hypothetical protein | 0.0066 | 0.0112 | 0.0314 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0041 | 0.0038 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0009 | 0.0006 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0035 | 0.0048 | 0.0173 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0018 | 0.001 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.006 | 0.0057 |
Mycobacterium ulcerans | hypothetical protein | 0.0167 | 0.0322 | 0.1069 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0055 | 0.0052 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0039 | 0.0036 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0009 | 0.0006 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.0404 | 0.0401 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0035 | 0.0048 | 0.0144 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0009 | 0.0006 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0026 | 0.0018 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0027 | 0.0006 |
Mycobacterium tuberculosis | Probable 3-hydroxyl-thioester dehydratase | 0.0023 | 0.0025 | 0.0058 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.1365 | 0.2796 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0018 | 0.0015 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.1365 | 0.2796 | 0.5 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.0536 | 0.1844 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0048 | 0.0996 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0036 | 0.0032 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0018 | 0.001 |
Echinococcus multilocularis | amyloid beta A4 protein | 0.0068 | 0.0117 | 0.0114 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0079 | 0.0075 |
Mycobacterium leprae | conserved hypothetical protein | 0.1365 | 0.2796 | 1 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0009 | 0.0004 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0047 | 0.0038 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0024 | 0.0027 | 0.0006 |
Brugia malayi | abnormal cell lineage protein 10 (Protein lin-10), putative | 0.0061 | 0.0103 | 0.0099 |
Mycobacterium tuberculosis | Conserved protein | 0.0066 | 0.0112 | 0.037 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0018 | 0.001 |
Mycobacterium leprae | conserved hypothetical protein | 0.0066 | 0.0112 | 0.0314 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | SCP-2 sterol transfer family protein | 0.0065 | 0.0112 | 0.0108 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.0221 | 0.0218 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.0536 | 0.0533 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0018 | 0.001 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0018 | 0.001 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0079 | 0.0075 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0043 | 0.0035 |
Leishmania major | 3-hydroxyacyl-ACP dehydratase, putative | 0.0023 | 0.0025 | 0.0061 |
Mycobacterium leprae | conserved hypothetical protein | 0.0066 | 0.0112 | 0.0314 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.0404 | 0.0401 |
Trichomonas vaginalis | set domain proteins, putative | 0.0235 | 0.0463 | 0.8559 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0039 | 0.0108 |
Loa Loa (eye worm) | ICD-1 protein | 0.0035 | 0.0048 | 0.0045 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0019 | 0.0015 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0132 | 0.0124 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0095 | 0.0174 | 0.0165 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.006 | 0.0057 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.0221 | 0.0218 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.1365 | 0.2796 | 0.5 |
Toxoplasma gondii | transporter, cation channel family protein | 0.002 | 0.0018 | 0.0032 |
Mycobacterium ulcerans | hypothetical protein | 0.0066 | 0.0112 | 0.0314 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.1365 | 0.2796 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0211 | 0.0412 | 0.1449 |
Mycobacterium ulcerans | hypothetical protein | 0.0066 | 0.0112 | 0.0314 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.1365 | 0.2796 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0009 | 0.0004 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.1365 | 0.2796 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0013 | 0.0009 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.1365 | 0.2796 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0038 | 0.0056 | 0.0053 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0134 | 0.013 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.0536 | 0.0533 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0018 | 0.001 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.0221 | 0.0218 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0084 | 0.0151 | 0.0454 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0024 | 0.0027 | 0.0024 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0012 | 0.0008 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0009 | 0.0001 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0018 | 0.001 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0095 | 0.0174 | 0.017 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0072 | 0.0125 | 0.0122 |
Mycobacterium tuberculosis | (3R)-hydroxyacyl-ACP dehydratase subunit HadC | 0.0066 | 0.0112 | 0.037 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0211 | 0.0412 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0074 | 0.0066 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0009 | 0.0033 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0012 | 0.0004 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0018 | 0.0015 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.002 | 0.0012 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0018 | 0.0015 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.1365 | 0.2796 | 1 |
Echinococcus granulosus | amyloid beta A4 protein | 0.0068 | 0.0117 | 0.0114 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0037 | 0.0033 |
Toxoplasma gondii | MaoC family domain-containing protein | 0.0101 | 0.0186 | 0.0634 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0039 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0068 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0037 | 0.0033 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0018 | 0.0015 |
Leishmania major | 3-hydroxyacyl-ACP dehydratase, putative | 0.0023 | 0.0025 | 0.0061 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0024 | 0.0027 | 0.0006 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0037 | 0.0028 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0012 | 0.0004 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0024 | 0.0027 | 0.0024 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0009 | 0.0004 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0095 | 0.0174 | 0.017 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0018 | 0.0015 |
Mycobacterium tuberculosis | (3R)-hydroxyacyl-ACP dehydratase subunit HadB | 0.0023 | 0.0025 | 0.0058 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0009 | 0.0006 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0104 | 0.0096 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0009 | 0.0006 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0112 | 0.0108 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0047 | 0.0074 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0167 | 0.0322 | 0.0318 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0018 | 0.001 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0095 | 0.0174 | 0.017 |
Echinococcus granulosus | transcription factor btf3 | 0.0035 | 0.0048 | 0.0045 |
Toxoplasma gondii | NAC domain-containing protein | 0.0035 | 0.0048 | 0.0141 |
Mycobacterium tuberculosis | Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. | 0.0167 | 0.0322 | 0.1121 |
Loa Loa (eye worm) | X11 protein | 0.0068 | 0.0117 | 0.0114 |
Mycobacterium tuberculosis | Conserved protein | 0.0024 | 0.0027 | 0.0064 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.005 | 0.0047 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.1365 | 0.2796 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0072 | 0.0125 | 0.0122 |
Onchocerca volvulus | 0.0028 | 0.0036 | 0.0017 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0084 | 0.0151 | 0.0148 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0018 | 0.0015 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0047 | 0.0074 | 0.0071 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0018 | 0.0015 |
Mycobacterium ulcerans | transcriptional regulator | 0.0065 | 0.0112 | 0.0313 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0037 | 0.0098 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0018 | 0.0015 |
Echinococcus multilocularis | transcription factor btf3 | 0.0035 | 0.0048 | 0.0045 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0058 | 0.0097 | 0.2186 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.011 | 0.0102 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.0095 | 0.0309 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0095 | 0.0174 | 0.017 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0036 | 0.0032 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0018 | 0.001 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0021 | 0.0021 | 0.0017 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0018 | 0.0015 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0024 | 0.0027 | 0.0068 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0009 | 0.0001 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0009 | 0.0006 |
Schistosoma mansoni | voltage-gated cation channel | 0.0095 | 0.0174 | 0.0165 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.01 | 0.0096 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0018 | 0.0013 | 0.0005 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0035 | 0.0048 | 0.0173 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0009 | 0.0001 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0211 | 0.0412 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0112 | 0.0108 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0024 | 0.0027 | 0.0466 |
Leishmania major | basic transcription factor 3a, putative | 0.0035 | 0.0048 | 0.0144 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.004 | 0.006 | 0.0057 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0048 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0174 | 0.017 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0803 | 0.1635 | 0.1632 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0026 | 0.0023 |
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.002 | 0.0017 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0013 | 0.0009 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0018 | 0.0015 |
Onchocerca volvulus | 0.0235 | 0.0463 | 0.0445 | |
Trypanosoma brucei | maoC-like dehydratase, putative | 0.0023 | 0.0025 | 0.0061 |
Mycobacterium ulcerans | hypothetical protein | 0.0065 | 0.0112 | 0.0313 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0095 | 0.0172 | 0.0169 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0095 | 0.0174 | 0.017 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0009 | 0.0006 |
Schistosoma mansoni | transcription factor btf3 | 0.0035 | 0.0048 | 0.004 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0009 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.0501 | 0.0498 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0018 | 0.0015 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0018 | 0.001 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0049 | 0.0046 |
Mycobacterium ulcerans | dehydratase | 0.0167 | 0.0322 | 0.1069 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0037 | 0.0131 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.0172 | 0.0169 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0019 | 0.0011 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0018 | 0.0015 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.1365 | 0.2796 | 1 |
Entamoeba histolytica | hypothetical protein | 0.1365 | 0.2796 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0079 | 0.0075 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0056 | 0.0048 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0027 | 0.0006 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | SCP-2 sterol transfer family protein | 0.0065 | 0.0112 | 0.0108 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.002 | 0.0018 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0015 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0009 | 0.0033 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.0084 | 0.0151 | 0.0148 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0018 | 0.001 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0009 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0122 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0015 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0037 | 0.0131 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0039 | 0.0141 |
Brugia malayi | jmjC domain containing protein | 0.0038 | 0.0056 | 0.0053 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.006 | 0.0057 |
Trypanosoma cruzi | maoC-like dehydratase, putative | 0.0023 | 0.0025 | 0.0423 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0043 | 0.0035 |
Brugia malayi | beta-NAC-like protein | 0.0035 | 0.0048 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0015 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0047 | 0.0074 | 0.0071 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0084 | 0.0151 | 0.0509 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0254 | 0.0501 | 0.0498 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.002 | 0.0017 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0026 | 0.0023 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0009 | 0.0006 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0018 | 0.0015 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0023 | 0.0025 | 0.0058 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0037 | 0.0018 |
Schistosoma mansoni | R-specific enoyl-CoA hydratase | 0.0023 | 0.0025 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0009 | 0.0001 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0039 | 0.0031 |
Loa Loa (eye worm) | calcium channel | 0.0095 | 0.0174 | 0.017 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0018 | 0.0015 |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.015 | 0.0286 | 0.0994 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0018 | 0.001 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0095 | 0.0172 | 0.0169 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0018 | 0.0015 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0018 | 0.0015 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0095 | 0.0174 | 0.017 |
Mycobacterium tuberculosis | Probable 3-hydroxyacyl-thioester dehydratase HtdY | 0.0167 | 0.0322 | 0.1121 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0043 | 0.004 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0038 | 0.0056 | 0.0048 |
Echinococcus multilocularis | sodium channel protein | 0.004 | 0.006 | 0.0057 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0047 | 0.0043 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0211 | 0.0412 | 0.1449 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0041 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0018 | 0.0015 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0037 | 0.0033 |
Onchocerca volvulus | 0.0072 | 0.0125 | 0.0107 | |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0036 | 0.0032 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0095 | 0.0174 | 0.017 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0036 | 0.0027 |
Mycobacterium ulcerans | hypothetical protein | 0.0066 | 0.0112 | 0.0314 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.0536 | 1 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0024 | 0.0027 | 0.0006 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0037 | 0.5 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0095 | 0.0174 | 0.0165 |
Echinococcus granulosus | voltage dependent calcium channel | 0.002 | 0.0018 | 0.0015 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0018 | 0.001 |
Onchocerca volvulus | 0.003 | 0.0039 | 0.0021 | |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0018 | 0.0015 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.005 | 0.0047 |
Brugia malayi | sterol carrier protein | 0.0065 | 0.0112 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0047 | 0.0043 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Binding affinity to corpus collosum myelin in central nervous system of mouse at 100 uM after 20 mins by fluorescent microscopy | ChEMBL. | 21391687 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.