Detailed information for compound 151193

Basic information

Technical information
  • TDR Targets ID: 151193
  • Name: [(2S)-3-[4-[(3-methoxyphenyl)methoxy]phenyl]- 2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydro gen phosphate
  • MW: 631.78 | Formula: C35H54NO7P
  • H donors: 3 H acceptors: 4 LogP: 8.7 Rotable bonds: 26
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](Cc1ccc(cc1)OCc1cccc(c1)OC)COP(=O)(O)O
  • InChi: 1S/C35H54NO7P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-35(37)36-32(29-43-44(38,39)40)26-30-22-24-33(25-23-30)42-28-31-19-18-20-34(27-31)41-2/h10-11,18-20,22-25,27,32H,3-9,12-17,21,26,28-29H2,1-2H3,(H,36,37)(H2,38,39,40)/b11-10-/t32-/m0/s1
  • InChiKey: WFNXESYFHAMZSY-ZWKXJJLDSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [(2S)-3-[4-[(3-methoxyphenyl)methoxy]phenyl]-2-[[(Z)-1-oxooctadec-9-enyl]amino]propyl] dihydrogen phosphate
  • [(2S)-3-(4-m-anisyloxyphenyl)-2-[[(Z)-octadec-9-enoyl]amino]propyl] dihydrogen phosphate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens lysophosphatidic acid receptor 3 Starlite/ChEMBL References
Homo sapiens lysophosphatidic acid receptor 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0762 0.2699
Echinococcus granulosus dna polymerase eta 0.0033 0.0145 0.035
Loa Loa (eye worm) hypothetical protein 0.0098 0.167 0.2483
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0047 0.0113
Echinococcus granulosus carboxylesterase 5A 0.0134 0.2511 0.6037
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0053 0.0604 0.1226
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0028 0.0026 0.0063
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0142 0.2697 0.5549
Plasmodium falciparum lysophospholipase, putative 0.0142 0.2697 0.9701
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0053 0.0604 0.1454
Echinococcus multilocularis acetylcholinesterase 0.0134 0.2511 0.6037
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0249 0.0739
Schistosoma mansoni inositol monophosphatase 0.0036 0.0222 0.0534
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0106 0.1868 0.6765
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0053 0.0604 0.1454
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0058 0.0139
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0056 0.0686 0.1651
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0659 0.1337
Echinococcus multilocularis solute carrier family 22 0.0029 0.0047 0.0113
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0252 0.0605
Schistosoma mansoni hypothetical protein 0.0167 0.3297 0.7928
Trypanosoma cruzi membrane transporter protein, putative 0.0034 0.0157 0.0414
Onchocerca volvulus 0.0029 0.0047 0.0029
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.103 0.3708
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0143 0.0212
Schistosoma mansoni organic anion transporter 0.0055 0.0659 0.1585
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Entamoeba histolytica P-glycoprotein-2 0.0031 0.0099 0.0241
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0058 0.0139
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.1887 0.6943
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0762 0.2699
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.103 0.0987
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0659 0.1337
Plasmodium falciparum thioredoxin reductase 0.0047 0.0462 0.1521
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0031 0.0099 0.0192
Schistosoma mansoni DNA polymerase eta 0.0033 0.0145 0.035
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0094 0.0227
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0897 0.1333
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0249 0.0739
Loa Loa (eye worm) sugar transporter 0.0029 0.0047 0.007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Loa Loa (eye worm) hypothetical protein 0.0036 0.0224 0.0334
Plasmodium vivax unspecified product 0.0145 0.2779 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0028 0.0026 0.0063
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0031 0.0099 0.0196
Schistosoma mansoni nAChR subunit 0.0053 0.0604 0.1454
Brugia malayi secreted modular calcium-binding protein 1 0.0038 0.0249 0.0504
Trypanosoma brucei DNA polymerase IV, putative 0.0053 0.0609 0.2122
Onchocerca volvulus 0.0029 0.0047 0.0029
Loa Loa (eye worm) hypothetical protein 0.0045 0.0436 0.0649
Echinococcus granulosus GPCR family 2 0.0031 0.0094 0.0227
Schistosoma mansoni nAChR subunit 0.0053 0.0604 0.1454
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0157 0.0414
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Onchocerca volvulus 0.0053 0.0604 0.1184
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0053 0.0604 0.1454
Toxoplasma gondii hypothetical protein 0.0145 0.2779 1
Plasmodium falciparum lysophospholipase, putative 0.0142 0.2697 0.9701
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.2286 0.5497
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0608
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.103 0.1531
Schistosoma mansoni follistatin 0.0038 0.0249 0.0598
Brugia malayi multidrug resistance protein 3 0.0031 0.0099 0.0201
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0897 0.2156
Schistosoma mansoni jumonji domain containing protein 0.0058 0.072 0.1731
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0774 0.073
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0604 0.1226
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.1887 0.4538
Loa Loa (eye worm) hypothetical protein 0.0072 0.1062 0.1579
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0604 0.1454
Onchocerca volvulus 0.0055 0.0659 0.1297
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0047 0.0096
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0124 0.2295 0.8483
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0236 0.4929 0.7329
Loa Loa (eye worm) agrin synaptic family protein 0.0038 0.0249 0.037
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0116 0.2102 0.5054
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0031 0.0099 0.0052
Schistosoma mansoni glucose transporter 0.0029 0.0047 0.0113
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.1887 0.6841
Schistosoma mansoni glucose transport protein 0.0029 0.0047 0.0113
Schistosoma mansoni multidrug resistance protein 0.0031 0.0099 0.0238
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Echinococcus granulosus acetylcholinesterase 0.0134 0.2511 0.6037
Giardia lamblia DINP protein human, muc B family 0.004 0.0299 1
Echinococcus granulosus multidrug resistance protein 1 0.0031 0.0099 0.0238
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.072 0.1731
Schistosoma mansoni lipoxygenase 0.0116 0.2102 0.5054
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1887 0.6752
Echinococcus granulosus nAChR subunit 0.0053 0.0604 0.1454
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0604 0.1226
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0249 0.0504
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0249 0.0504
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0604 0.1454
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0047 0.005
Brugia malayi hypothetical protein 0.0029 0.0047 0.0095
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0053 0.0604 0.0899
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0204 0.4158 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.167 0.2483
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0099 0.0238
Entamoeba histolytica P-glycoprotein-5 0.0031 0.0099 0.0241
Echinococcus multilocularis solute carrier family 22 0.0029 0.0047 0.0113
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0774 0.1861
Plasmodium vivax glutathione reductase, putative 0.0047 0.0462 0.1521
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1887 0.2806
Plasmodium falciparum glutathione reductase 0.0047 0.0462 0.1521
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Loa Loa (eye worm) hypothetical protein 0.0028 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0086
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Plasmodium vivax hexose transporter 0.0029 0.0047 0.0002
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1887 0.6752
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Schistosoma mansoni voltage-gated potassium channel 0.0106 0.1856 0.4463
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.1887 0.6943
Brugia malayi Voltage-gated potassium channel, Shal-family (KCND, Kv4-like) alpha-subunit. C. elegans shl-1 ortholog 0.0082 0.129 0.2617
Echinococcus multilocularis conserved hypothetical protein 0.0045 0.0436 0.1049
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.1887 1
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0222 0.0534
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.103 0.0987
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.003 0.0079 0.0189
Trichomonas vaginalis esterase, putative 0.0071 0.103 0.2118
Loa Loa (eye worm) CYP4Cod1 0.0033 0.0143 0.0212
Mycobacterium tuberculosis Probable dehydrogenase 0.0106 0.1868 0.1829
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0094 0.0192
Loa Loa (eye worm) glutathione reductase 0.0047 0.0462 0.0687
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0051 0.0575 0.1384
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0897 0.3206
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.103 0.3708
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0028 0.0026 0.0063
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0053 0.0604 0.0899
Echinococcus granulosus solute carrier family 22 0.0029 0.0047 0.0113
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0765 0.184
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0047 0.0097
Toxoplasma gondii facilitative glucose transporter GT1 0.0029 0.0047 0.0002
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0604 0.1454
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0106 0.1868 0.1829
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Echinococcus multilocularis shaker cognate 0.0028 0.0026 0.0063
Brugia malayi Thioredoxin reductase 0.0047 0.0462 0.0938
Mycobacterium tuberculosis Probable reductase 0.0106 0.1868 0.1829
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Loa Loa (eye worm) hypothetical protein 0.0031 0.0091 0.0135
Onchocerca volvulus 0.0029 0.0047 0.0029
Loa Loa (eye worm) hypothetical protein 0.0031 0.0099 0.0147
Onchocerca volvulus 0.0055 0.0659 0.1297
Loa Loa (eye worm) voltage-dependent calcium channel 0.0094 0.1584 0.2355
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0116 0.2102 0.5054
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0204 0.4158 1
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0157 0.0414
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0143 0.0361
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0032 0.0078
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0774 0.1861
Brugia malayi Pre-SET motif family protein 0.0205 0.4194 0.8508
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0659 0.1297
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Trypanosoma brucei monoglyceride lipase, putative 0.0142 0.2697 1
Loa Loa (eye worm) multidrug resistance protein 3 0.0031 0.0099 0.0147
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.103 0.2118
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0031 0.0099 0.0204
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.103 0.0987
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.103 0.2476
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0053 0.0604 0.1226
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0134 0.2511 0.6037
Mycobacterium ulcerans DNA polymerase IV 0.0059 0.0762 0.2699
Schistosoma mansoni voltage-gated potassium channel 0.0059 0.0765 0.184
Plasmodium vivax hypothetical protein, conserved 0.0071 0.103 0.3598
Echinococcus multilocularis nAChR subunit 0.0053 0.0604 0.1454
Schistosoma mansoni hypothetical protein 0.0167 0.3297 0.7928
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0047 0.007
Brugia malayi major facilitator superfamily protein 0.0029 0.0047 0.0095
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0053 0.0604 0.1226
Schistosoma mansoni multidrug resistance protein 0.0031 0.0099 0.0238
Loa Loa (eye worm) hypothetical protein 0.0045 0.0436 0.0649
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0604 0.1454
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0059 0.0762 0.1568
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1887 0.4538
Loa Loa (eye worm) sugar transporter 0.0029 0.0047 0.007
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0047 0.0002
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.072 0.1731
Plasmodium falciparum lysophospholipase, putative 0.0145 0.2779 1
Schistosoma mansoni glucose transport protein 0.0029 0.0047 0.0113
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0053 0.0604 0.1454
Loa Loa (eye worm) inositol-1 0.0036 0.0222 0.033
Echinococcus multilocularis sodium channel protein 0.0122 0.2227 0.5355
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0053 0.0604 0.0899
Loa Loa (eye worm) hypothetical protein 0.0134 0.2511 0.3733
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0604 0.1226
Echinococcus multilocularis nAChR subunit 0.0028 0.0033 0.0079
Echinococcus multilocularis solute carrier family 22 0.0029 0.0047 0.0113
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0222 0.0457
Onchocerca volvulus 0.0053 0.0604 0.1184
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0099 0.0238
Schistosoma mansoni nAChR subunit 0.0053 0.0604 0.1454
Echinococcus granulosus follistatin 0.0038 0.0249 0.0598
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.0031 0.0087 0.021
Schistosoma mansoni hypothetical protein 0.0124 0.2286 0.5497
Loa Loa (eye worm) hypothetical protein 0.0106 0.1856 0.276
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0058 0.0139
Mycobacterium leprae Probable lipase LipE 0.0071 0.103 0.3499
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.103 0.3708
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0106 0.1856 0.3765
Echinococcus multilocularis voltage dependent calcium channel 0.0204 0.4158 1
Brugia malayi hypothetical protein 0.0055 0.0659 0.1337
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Echinococcus granulosus solute carrier family 22 0.0029 0.0047 0.0113
Entamoeba histolytica P-glycoprotein-2, putative 0.0031 0.0099 0.0241
Onchocerca volvulus 0.0071 0.103 0.2065
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0249 0.0739
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0462 0.1567
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0604 0.0899
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.103 0.2476
Trypanosoma cruzi MFS transporter, putative 0.0055 0.0659 0.2309
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0608
Loa Loa (eye worm) hypothetical protein 0.0055 0.0659 0.098
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0056 0.0686 0.1021
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.2697 0.5549
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.1887 0.4538
Loa Loa (eye worm) kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0249 0.037
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0047 0.0096
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0099 0.0238
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0157 0.0414
Brugia malayi major facilitator superfamily protein 0.0029 0.0047 0.0095
Echinococcus granulosus potassium voltage gated channel protein 0.0028 0.0026 0.0063
Loa Loa (eye worm) hypothetical protein 0.0071 0.103 0.1531
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0941 0.1908
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0026 0.0063
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0047 0.0002
Echinococcus granulosus voltage dependent calcium channel 0.0094 0.1584 0.3809
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.103 0.3708
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0099 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0053 0.0604 0.1454
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0604 0.1226
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0604 0.1454
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0094 0.014
Toxoplasma gondii ABC1 family protein 0.0071 0.103 0.3598
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0462 0.0417
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0145 0.0099
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.167 0.3388
Echinococcus multilocularis GPCR, family 2 0.0031 0.0094 0.0227
Schistosoma mansoni thyroid hormone receptor 0.0142 0.2696 0.6484
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0099 0.0238
Loa Loa (eye worm) hypothetical protein 0.0051 0.0573 0.0853
Loa Loa (eye worm) carboxylesterase 0.0134 0.2511 0.3733
Echinococcus multilocularis voltage gated potassium channel 0.003 0.0079 0.0189
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0099 0.0204
Onchocerca volvulus 0.0029 0.0047 0.0029
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0058 0.0139
Brugia malayi follicle stimulating hormone receptor 0.0236 0.4929 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Loa Loa (eye worm) hypothetical protein 0.0071 0.103 0.1531
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0142 0.2697 0.5549
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1887 0.6943
Toxoplasma gondii sugar transporter ST2 0.0029 0.0047 0.0002
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0604 0.1454
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0047 0.0096
Trichomonas vaginalis set domain proteins, putative 0.0233 0.4861 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0033 0.0067
Brugia malayi Inositol-1 0.0036 0.0222 0.0451
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Loa Loa (eye worm) hypothetical protein 0.0072 0.1062 0.1579
Echinococcus granulosus Solute carrier organic anion transporter family 0.0055 0.0659 0.1585
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0774 0.2662
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0094 0.0227
Leishmania major DNA polymerase kappa, putative 0.004 0.0299 0.0949
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0047 0.0096
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0028 0.0026 0.0053
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0099 0.0204
Schistosoma mansoni organic anion transporter 0.0055 0.0659 0.1585
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0145 0.041
Schistosoma mansoni multidrug resistance protein 0.0034 0.0157 0.0377
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1887 0.3882
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.1887 0.4538
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1887 0.3882
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0462 0.0687
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0106 0.1856 0.4463
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.103 0.2118
Schistosoma mansoni hypothetical protein 0.0067 0.0941 0.2262
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0118 0.2147 0.7854
Loa Loa (eye worm) hypothetical protein 0.0055 0.0659 0.098
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Trichomonas vaginalis abcb9, putative 0.0031 0.0099 0.0204
Trypanosoma brucei unspecified product 0.0053 0.0609 0.2122
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0033 0.0143 0.0361
Onchocerca volvulus 0.0029 0.0047 0.0029
Brugia malayi glutathione reductase 0.0047 0.0462 0.0938
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.167 0.3388
Loa Loa (eye worm) Kv4.2 voltage-gated potassium channel 0.0029 0.0054 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0082 0.129 0.3102
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0222 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0249 0.037
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0604 0.1454
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.072 0.1731
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Brugia malayi 6-phosphofructokinase 0.0107 0.1887 0.3828
Plasmodium falciparum hexose transporter 0.0029 0.0047 0.0002
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0604 0.1454
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Onchocerca volvulus Putative nachr subunit 0.0053 0.0604 0.1184
Entamoeba histolytica P-glyco protein 6, putative 0.0031 0.0099 0.0241
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0106 0.1868 0.1829
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0045 0.0436 0.1049
Loa Loa (eye worm) hypothetical protein 0.0094 0.1584 0.2355
Echinococcus multilocularis ATP binding cassette sub family B 0.0031 0.0091 0.0219
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0157 0.0414
Echinococcus multilocularis Solute carrier organic anion transporter family 0.0055 0.0659 0.1585
Mycobacterium leprae conserved hypothetical protein 0.0071 0.103 0.3499
Echinococcus granulosus nAChR subunit 0.0028 0.0033 0.0079
Echinococcus granulosus agrin 0.0038 0.0249 0.0598
Mycobacterium ulcerans lysophospholipase 0.0142 0.2697 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0659 0.098
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0047 0.0095
Plasmodium vivax sugar transporter, putative 0.0029 0.0047 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1887 0.3882
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0047 0.0113
Echinococcus multilocularis transfer RNA-Gly 0.0028 0.0026 0.0063
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0222 0.0661
Schistosoma mansoni sugar transporter 0.0029 0.0047 0.0113
Loa Loa (eye worm) hypothetical protein 0.0055 0.0659 0.098
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0056 0.0686 0.1393
Onchocerca volvulus 0.0029 0.0047 0.0029
Onchocerca volvulus 0.0029 0.0047 0.0029
Loa Loa (eye worm) hypothetical protein 0.01 0.1721 0.2559
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.103 0.0987
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0299 0.0949
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Loa Loa (eye worm) hypothetical protein 0.0134 0.2511 0.3733
Loa Loa (eye worm) hypothetical protein 0.0204 0.4158 0.6183
Toxoplasma gondii sugar transporter ST3 0.0029 0.0047 0.0002
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0299 0.0949
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0142 0.2697 0.5549
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0774 0.2743
Brugia malayi Cytochrome P450 family protein 0.0033 0.0143 0.0289
Schistosoma mansoni sugar transporter 0.0029 0.0047 0.0113
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0094 0.0227
Loa Loa (eye worm) hypothetical protein 0.0031 0.0099 0.0147
Loa Loa (eye worm) hypothetical protein 0.0033 0.0145 0.0216
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0094 0.0192
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0249 0.0504
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0053 0.0604 0.1454
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0145 0.035
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Echinococcus multilocularis multidrug resistance protein 1 0.0031 0.0099 0.0238
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.01 0.1717 0.4128
Echinococcus multilocularis thyroid hormone receptor alpha 0.0142 0.2696 0.6484
Echinococcus granulosus potassium voltage gated channel protein 0.0045 0.0436 0.1049
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0659 0.1297
Loa Loa (eye worm) hypothetical protein 0.0067 0.0941 0.1399
Mycobacterium tuberculosis Conserved protein 0.0071 0.103 0.0987
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0099 0.0204
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0031 0.0099 0.0204
Schistosoma mansoni glucose transport protein 0.0029 0.0047 0.0113
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.4194 0.6236
Brugia malayi SPARC precursor 0.0038 0.0249 0.0504
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0047 0.0097
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0897 0.3206
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.103 0.2089
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0031 0.0099 0.0192
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0106 0.1868 0.1829
Onchocerca volvulus 0.0071 0.103 0.2065
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Loa Loa (eye worm) GABA receptor subunit 0.0028 0.0033 0.0049
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Giardia lamblia Sugar-proton symporter 0.0029 0.0047 0.0021
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0053 0.0604 0.1454
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0029 0.0047 0.0113
Leishmania major DNA polymerase eta, putative 0.0033 0.0145 0.0371
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.02 0.0481
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0034 0.0157 0.0377
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0053 0.0604 0.1226
Schistosoma mansoni nAChR subunit 0.0053 0.0604 0.1454
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0118 0.2147 0.211
Brugia malayi jmjC domain containing protein 0.0058 0.072 0.146
Plasmodium falciparum esterase, putative 0.0145 0.2779 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0099 0.0204
Leishmania major monoglyceride lipase, putative 0.0142 0.2697 1
Echinococcus granulosus geminin 0.0167 0.3297 0.7928
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Brugia malayi sodium-independent organic anion transporter family protein 0.0055 0.0659 0.1337
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi Cytochrome P450 family protein 0.0033 0.0143 0.0289
Loa Loa (eye worm) hypothetical protein 0.0071 0.103 0.1531
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0122 0.2227 0.5355
Onchocerca volvulus 0.0029 0.0047 0.0029
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0047 0.0113
Schistosoma mansoni nAChR subunit 0.0053 0.0604 0.1454
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Plasmodium falciparum esterase, putative 0.0142 0.2697 0.9701
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0053 0.0604 0.1454
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0165 0.0339
Plasmodium falciparum lysophospholipase, putative 0.0142 0.2697 0.9701
Leishmania major hypothetical protein, conserved 0.0034 0.0157 0.0414
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.1887 0.6752
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0058 0.0139
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Mycobacterium ulcerans hypothetical protein 0.0071 0.103 0.3708
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0099 0.0204
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0053 0.0604 0.0899
Loa Loa (eye worm) calcium channel 0.0204 0.4158 0.6183
Onchocerca volvulus 0.0029 0.0047 0.0029
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0028 0.0026 0.0053
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0099 0.0204
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Echinococcus multilocularis dna polymerase eta 0.0033 0.0145 0.035
Schistosoma mansoni sugar transporter 0.0029 0.0047 0.0113
Schistosoma mansoni voltage-gated cation channel 0.0204 0.4158 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0026 0.0063
Leishmania major hypothetical protein, conserved 0.0034 0.0157 0.0414
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0142 0.2697 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi polk-prov protein 0.0036 0.0224 0.0455
Schistosoma mansoni inositol monophosphatase 0.0036 0.0222 0.0534
Entamoeba histolytica P-glycoprotein 5, putative 0.0031 0.0099 0.0241
Giardia lamblia Hexose transporter 0.0029 0.0047 0.0021
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0145 0.035
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Schistosoma mansoni nAChR subunit 0.0053 0.0604 0.1454
Toxoplasma gondii sugar transporter ST1 0.0029 0.0047 0.0002
Echinococcus granulosus glycine receptor subunit alpha 1 0.0053 0.0604 0.1454
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0157 0.0414
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0222 0.0661
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0204 0.4158 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0204 0.4158 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0099 0.0238
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0028 0.0026 0.0063
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0118 0.2147 0.211
Onchocerca volvulus 0.0233 0.4861 1
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0222 0.0643
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0053 0.0604 0.0899
Plasmodium vivax lysophospholipase, putative 0.0145 0.2779 1
Toxoplasma gondii hypothetical protein 0.0072 0.1062 0.3716
Plasmodium vivax multidrug resistance protein 1, putative 0.0031 0.0099 0.0192
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi hypothetical protein 0.0055 0.0659 0.1337
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.003 0.0079 0.0159
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0028 0.0033 0.0067
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0099 0.0204
Schistosoma mansoni hypothetical protein 0.0031 0.0094 0.0227
Brugia malayi prostaglandin transporter 0.0055 0.0659 0.1337
Mycobacterium ulcerans lipase LipD 0.0071 0.103 0.3708
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0031 0.0099 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0035
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0145 0.0371
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Echinococcus granulosus acetylcholinesterase 0.0134 0.2511 0.6037
Schistosoma mansoni hypothetical protein 0.0031 0.0094 0.0227
Trypanosoma brucei cytochrome P450, putative 0.0033 0.0143 0.0361
Brugia malayi Pre-SET motif family protein 0.0029 0.0058 0.0117
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Trypanosoma brucei trypanothione reductase 0.0047 0.0462 0.1567
Schistosoma mansoni nAChR subunit 0.0053 0.0604 0.1454
Entamoeba histolytica P-glycoprotein-2 0.0031 0.0099 0.0241
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0053 0.0604 0.1454
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Schistosoma mansoni multidrug resistance protein 0.0031 0.0099 0.0238
Brugia malayi Kazal-type serine protease inhibitor domain containing protein 0.0038 0.0249 0.0504
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0091 0.1515 0.554
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0029 0.0047 0.0113
Schistosoma mansoni agrin 0.0038 0.0249 0.0598
Echinococcus multilocularis voltage gated potassium channel 0.0028 0.0026 0.0063
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0608
Echinococcus granulosus voltage dependent calcium channel 0.0204 0.4158 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.072 0.107
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Loa Loa (eye worm) phosphofructokinase 0.0107 0.1887 0.2806
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.103 0.2476
Brugia malayi hypothetical protein 0.0035 0.02 0.0406
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0047 0.0097
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0204 0.4158 1
Echinococcus multilocularis potassium voltage gated channel protein 0.0104 0.1812 0.4356
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0099 0.0204
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0462 0.1112
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.103 0.0987
Onchocerca volvulus 0.0029 0.0047 0.0029
Brugia malayi Carboxylesterase family protein 0.0134 0.2511 0.5093
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.02 0.0481
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0897 0.3146
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0056 0.0686 0.1651
Toxoplasma gondii transporter, cation channel family protein 0.0094 0.1584 0.5626
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0058 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0053 0.0604 0.1226
Onchocerca volvulus 0.0029 0.0047 0.0029
Echinococcus multilocularis voltage dependent calcium channel 0.0204 0.4158 1
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0047 0.0113
Onchocerca volvulus 0.0029 0.0058 0.0052
Echinococcus multilocularis carboxylesterase 5A 0.0134 0.2511 0.6037
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0145 0.2779 1
Echinococcus granulosus organic anion transporting polypeptide 30B 0.0055 0.0659 0.1585
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0897 0.3206
Echinococcus multilocularis follistatin 0.0038 0.0249 0.0598
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0204 0.4158 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0897 0.3206
Brugia malayi Sugar transporter family protein 0.0029 0.0047 0.0095
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0028 0.0033 0.0067
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0034 0.0157 0.0377
Entamoeba histolytica hypothetical protein 0.0035 0.02 0.0608
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0222 0.0534
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.1887 0.3882
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Trichomonas vaginalis ABC transporter, putative 0.0031 0.0099 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0224 0.0669
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Echinococcus multilocularis glycine receptor subunit beta 0.0053 0.0604 0.1454
Brugia malayi excitatory GABA receptor EXP-1A 0.0053 0.0604 0.1226
Brugia malayi Sugar transporter family protein 0.0029 0.0047 0.0095
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0774 0.2743
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0047 0.0113
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0897 0.2156
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0099 0.0238
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0204 0.4158 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0099 0.0204
Trypanosoma cruzi cytochrome P450, putative 0.0033 0.0143 0.0361
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0053 0.0604 0.1454
Brugia malayi 6-phosphofructokinase 0.0107 0.1895 0.3845
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0252 0.0605
Brugia malayi Cation transporter family protein 0.0053 0.0604 0.1226
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0058 0.0041
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0099 0.0204
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0094 0.0227
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.02 0.0481
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.1887 0.6943
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0047 0.0113
Echinococcus granulosus multidrug resistance protein 1 0.0031 0.0099 0.0238
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Echinococcus granulosus solute carrier family 22 0.0029 0.0047 0.0113
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0031 0.0091 0.0219
Echinococcus granulosus potassium voltage gated channel protein 0.0106 0.1856 0.4463
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Leishmania major p-glycoprotein 0.0031 0.0099 0.0196
Loa Loa (eye worm) acetylcholinesterase 1 0.0134 0.2511 0.3733
Trypanosoma cruzi monoglyceride lipase, putative 0.0142 0.2697 1
Brugia malayi Cation transporter family protein 0.0053 0.0604 0.1226
Echinococcus granulosus potassium voltage gated channel subfamily H 0.003 0.0079 0.0189
Loa Loa (eye worm) hypothetical protein 0.0071 0.103 0.1531
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0047 0.0095
Echinococcus multilocularis organic anion transporting polypeptide 30B 0.0055 0.0659 0.1585
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0204 0.4158 0.8437
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0058 0.0139
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0204 0.4158 1
Echinococcus multilocularis acetylcholinesterase 0.0134 0.2511 0.6037
Echinococcus multilocularis solute carrier family 22 0.0029 0.0047 0.0113
Trypanosoma brucei monoglyceride lipase, putative 0.0142 0.2697 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0035
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0031 0.0099 0.0204
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0222 0.0689
Onchocerca volvulus 0.0071 0.103 0.2065
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0142 0.2697 0.9702
Trichomonas vaginalis abcb9, putative 0.0031 0.0099 0.0204
Echinococcus granulosus shaker cognate 0.0028 0.0026 0.0063
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0604 0.1454
Trypanosoma brucei MATE efflux family protein, putative 0.0034 0.0157 0.0414
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi Sugar transporter family protein 0.0029 0.0047 0.0095
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0047 0.0097
Brugia malayi hypothetical protein 0.012 0.2189 0.4442
Loa Loa (eye worm) hypothetical protein 0.0055 0.0659 0.098
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0165 0.0339
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0897 0.1819
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0157 0.0414
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Trichomonas vaginalis DNA polymerase eta, putative 0.0059 0.0762 0.1568
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0047 0.0113
Brugia malayi hypothetical protein 0.0029 0.0047 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0031 0.0099 0.0147
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.0762 0.2699
Trichomonas vaginalis abcb9, putative 0.0031 0.0099 0.0204
Brugia malayi beta-lactamase family protein 0.0071 0.103 0.2089
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0604 0.1226
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0462 0.1112
Onchocerca volvulus Putative organic anion transporter 0.0055 0.0659 0.1297
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0142 0.2697 0.5549
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0774 0.2743
Mycobacterium tuberculosis Conserved protein 0.0071 0.103 0.0987
Toxoplasma gondii Kazal-type serine protease inhibitor domain-containing protein 0.0038 0.0249 0.0739
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0222 0.0457
Loa Loa (eye worm) sodium-independent organic anion transporter 0.0055 0.0659 0.098
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0222 0.0661
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0299 0.0253
Loa Loa (eye worm) hypothetical protein 0.0313 0.6726 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0047 0.007
Echinococcus granulosus voltage gated potassium channel 0.0028 0.0026 0.0063
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0047 0.0097
Loa Loa (eye worm) hypothetical protein 0.0031 0.0094 0.014
Loa Loa (eye worm) hypothetical protein 0.0055 0.0659 0.098
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0028 0.0026 0.0063
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0045 0.0436 0.1049
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.0224 0.0669
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0031 0.0099 0.0238
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0145 0.0295
Onchocerca volvulus 0.0029 0.0047 0.0029
Onchocerca volvulus Putative transporter 0.0029 0.0047 0.0029
Brugia malayi hypothetical protein 0.01 0.1721 0.3492
Onchocerca volvulus 0.0053 0.0604 0.1184
Brugia malayi Cation transporter family protein 0.0053 0.0604 0.1226
Toxoplasma gondii transporter, major facilitator family protein 0.0055 0.0659 0.2241
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.1887 0.2806
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0099 0.0204
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0099 0.0238
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0029 0.0047 0.0113
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0099 0.0204
Loa Loa (eye worm) ACC-1 protein 0.0053 0.0604 0.0899
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0028 0.0026 0.0063
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.072 0.1731
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0157 0.0414
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0145 0.0216
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0774 0.1861
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0028 0.0033 0.0079
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0145 0.035
Schistosoma mansoni thyroid hormone receptor 0.0142 0.2696 0.6484
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0132 0.0086
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi hypothetical protein 0.0029 0.0047 0.0095
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0053 0.0604 0.1226
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0028 0.0033 0.0079
Schistosoma mansoni hypothetical protein 0.0029 0.0047 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0047 0.0097
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0053 0.0604 0.1226
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0047 0.0095
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0774 0.2743
Schistosoma mansoni hypothetical protein 0.0035 0.02 0.0481
Loa Loa (eye worm) hypothetical protein 0.0071 0.103 0.1531
Loa Loa (eye worm) hypothetical protein 0.0038 0.0249 0.037
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Schistosoma mansoni hypothetical protein 0.0031 0.0094 0.0227
Schistosoma mansoni sugar transporter 0.0029 0.0047 0.0113
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0026 0.0063
Onchocerca volvulus 0.0055 0.0659 0.1297
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0222 0.0457
Trypanosoma brucei membrane transporter protein, putative 0.0034 0.0157 0.0414
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0047 0.0113
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0029 0.0047 0.0113
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.103 0.2476
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0026 0.0063
Brugia malayi phosphofructokinase 0.0107 0.1887 0.3828
Onchocerca volvulus 0.0053 0.0604 0.1184
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.103 0.2118
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.103 0.0987
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0047 0.0096
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.103 0.0987
Loa Loa (eye worm) hypothetical protein 0.0038 0.0249 0.037
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Plasmodium vivax PST-A protein 0.0142 0.2697 0.9701
Schistosoma mansoni vesicular amine transporter 0.0028 0.0026 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Loa Loa (eye worm) hypothetical protein 0.003 0.0079 0.0117
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0604 0.1454
Entamoeba histolytica P-glycoprotein-1 0.0031 0.0099 0.0241
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0053 0.0604 0.1454
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0222 0.0661
Onchocerca volvulus 0.0055 0.0659 0.1297
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0053 0.0604 0.1454
Echinococcus granulosus voltage gated potassium channel 0.003 0.0079 0.0189
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0031 0.0099 0.0204
Brugia malayi Carboxylesterase family protein 0.0134 0.2511 0.5093
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0031 0.0099 0.0238
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0222 0.0661
Toxoplasma gondii protease inhibitor PI2 0.0038 0.0249 0.0739
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0604 0.1454
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0204 0.4158 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi jmjC domain containing protein 0.0058 0.072 0.146
Plasmodium falciparum esterase, putative 0.0145 0.2779 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Onchocerca volvulus 0.0053 0.0604 0.1184
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0028 0.0033 0.0067
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Echinococcus granulosus dna polymerase kappa 0.0059 0.0762 0.1833
Mycobacterium ulcerans hypothetical protein 0.0142 0.2697 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.2286 0.5497
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0604 0.1226
Loa Loa (eye worm) LGC-31 protein 0.0053 0.0604 0.0899
Mycobacterium tuberculosis Possible lysophospholipase 0.0142 0.2697 0.2663
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0462 0.1521
Trichomonas vaginalis conserved hypothetical protein 0.0142 0.2697 0.5549
Schistosoma mansoni voltage-gated potassium channel 0.0104 0.1812 0.4356
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0047 0.0096
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0145 0.0371
Loa Loa (eye worm) hypothetical protein 0.0055 0.0659 0.098
Leishmania major cytochrome p450-like protein 0.0033 0.0143 0.0361
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Loa Loa (eye worm) hypothetical protein 0.0053 0.0604 0.0899
Loa Loa (eye worm) hypothetical protein 0.0038 0.0249 0.037
Echinococcus granulosus sodium channel protein 0.0091 0.1515 0.3644
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0026 0.0063
Onchocerca volvulus 0.0029 0.0047 0.0029
Onchocerca volvulus 0.0029 0.0047 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0079 0.0189
Onchocerca volvulus 0.0053 0.0604 0.1184
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.072 0.1731
Echinococcus multilocularis expressed protein 0.0038 0.0249 0.0598
Schistosoma mansoni hypothetical protein 0.0031 0.0094 0.0227
Onchocerca volvulus 0.0038 0.0249 0.0447
Schistosoma mansoni voltage-gated potassium channel 0.003 0.0079 0.0189
Echinococcus multilocularis dna polymerase kappa 0.0059 0.0762 0.1833
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0142 0.2697 0.9702
Trichomonas vaginalis conserved hypothetical protein 0.0145 0.2779 0.5717
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0145 0.035
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.103 0.2118
Mycobacterium tuberculosis Probable oxidoreductase 0.0118 0.2147 0.211
Brugia malayi beta-lactamase 0.0071 0.103 0.2089
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Echinococcus multilocularis agrin 0.0038 0.0249 0.0598
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.1887 0.1849
Brugia malayi beta-lactamase family protein 0.0071 0.103 0.2089
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Schistosoma mansoni smdr2 0.0031 0.0099 0.0238
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0142 0.2697 0.5549
Loa Loa (eye worm) hypothetical protein 0.0029 0.0047 0.007
Leishmania major trypanothione reductase 0.0047 0.0462 0.1567
Mycobacterium ulcerans beta-lactamase 0.0071 0.103 0.3708
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0124 0.2295 0.8483
Onchocerca volvulus 0.0029 0.0047 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.0059 0.0762 0.2699
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Leishmania major hypothetical protein, conserved 0.0071 0.103 0.3708
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0031 0.0099 0.0204
Loa Loa (eye worm) hypothetical protein 0.0028 0.0033 0.0049
Trichomonas vaginalis taga, putative 0.0031 0.0099 0.0204
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0145 0.0295
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.103 0.3708
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0053 0.0604 0.1454
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0774 0.1861
Mycobacterium tuberculosis Conserved protein 0.0071 0.103 0.0987
Echinococcus multilocularis multidrug resistance protein 1 0.0031 0.0099 0.0238
Echinococcus granulosus solute carrier family 22 0.0029 0.0047 0.0113
Loa Loa (eye worm) voltage-gated potassium channel 0.0028 0.0026 0.0039
Schistosoma mansoni lipoxygenase 0.0081 0.1278 0.3074
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0047 0.0097
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0604 0.1226
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0053 0.0604 0.0899
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0053 0.0604 0.1454
Plasmodium falciparum multidrug resistance protein 1 0.0031 0.0099 0.0192
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0053 0.0604 0.1454
Echinococcus multilocularis potassium voltage gated channel protein 0.0106 0.1856 0.4463
Echinococcus granulosus potassium voltage gated channel protein 0.0104 0.1812 0.4356
Onchocerca volvulus 0.0055 0.0659 0.1297
Echinococcus multilocularis geminin 0.0167 0.3297 0.7928
Brugia malayi ABC transporter family protein 0.0031 0.0099 0.0201
Schistosoma mansoni neurotransmitter gated ion channel 0.0028 0.0033 0.0079
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0029 0.0047 0.0113
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0053 0.0604 0.1226
Onchocerca volvulus 0.0029 0.0047 0.0029
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.072 0.1731
Loa Loa (eye worm) hypothetical protein 0.0071 0.103 0.1531
Toxoplasma gondii thioredoxin reductase 0.0047 0.0462 0.1521
Schistosoma mansoni voltage-gated potassium channel 0.0106 0.1856 0.4463
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0142 0.2697 0.5549
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0053 0.0604 0.1454
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0047 0.0096
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0053 0.0604 0.1454
Echinococcus granulosus multidrug resistance protein 1 0.0031 0.0099 0.0238
Plasmodium vivax SET domain protein, putative 0.0029 0.0058 0.0041
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0897 0.2156
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0053 0.0604 0.1226
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0051 0.0575 0.1384
Loa Loa (eye worm) cytochrome P450 family protein 0.0033 0.0143 0.0212
Echinococcus granulosus glycine receptor subunit beta 0.0053 0.0604 0.1454
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0106 0.1868 0.1829
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.103 0.2118
Onchocerca volvulus 0.0031 0.0099 0.0137
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0036 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0056 0.0035
Loa Loa (eye worm) beta-lactamase 0.0071 0.103 0.1531

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 642 nM In vitro antagonism of LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 3 in HEK293T cell lines ChEMBL. 15125924
IC50 (functional) = 642 nM In vitro antagonism of LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 3 in HEK293T cell lines ChEMBL. 15125924
IC50 (functional) = 5660 nM In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines ChEMBL. 15125924
IC50 (functional) = 5660 nM In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines ChEMBL. 15125924
Ki (functional) = 358 nM In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines ChEMBL. 15125924
Ki (functional) = 358 nM In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines ChEMBL. 15125924

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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