Detailed information for compound 1512993

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 392.484 | Formula: C19H36O8
  • H donors: 6 H acceptors: 6 LogP: 0.15 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@@H]1O[C@H](O[C@H]2C[C@H](C)[C@](C(C2)(C)C)(O)CC[C@@H](O)C)[C@H]([C@@H]([C@H]1O)O)O
  • InChi: 1S/C19H36O8/c1-10-7-12(8-18(3,4)19(10,25)6-5-11(2)21)26-17-16(24)15(23)14(22)13(9-20)27-17/h10-17,20-25H,5-9H2,1-4H3/t10-,11-,12-,13-,14-,15+,16-,17-,19+/m0/s1
  • InChiKey: ARLXZLBJVXNRGP-GFFWZXEVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0009 0.0003
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0087 0.0862
Echinococcus granulosus Chromo domain 0.0117 0.0173 0.0172
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0228
Mycobacterium leprae conserved hypothetical protein 0.012 0.0178 0.6687
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0087 0.1406
Loa Loa (eye worm) acetylcholine receptor protein 0.0202 0.0344 0.0477
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.001 0.0024
Brugia malayi intermediate filament protein 0.0168 0.0275 0.0381
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0012 0.0014
Trichomonas vaginalis bromodomain containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0236 0.0412 0.0572
Toxoplasma gondii bromodomain-containing protein 0.0046 0.0032 0.0233
Toxoplasma gondii hypothetical protein 0.012 0.0178 0.1739
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0082 0.0104 0.1716
Schistosoma mansoni nAChR subunit 0.0439 0.0816 0.0816
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Echinococcus granulosus geminin 0.0351 0.0641 0.064
Onchocerca volvulus Alhambra homolog 0.0061 0.0061 0.0074
Loa Loa (eye worm) hypothetical protein 0.0713 0.1365 0.1897
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0036 0.0012 0.0047
Echinococcus multilocularis GPCR, family 2 0.0243 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0168 0.0275 0.0381
Echinococcus granulosus serine threonine protein kinase 0.0109 0.0158 0.0157
Trichomonas vaginalis bromodomain-containing protein 3, brd3, putative 0.0046 0.0032 0.0039
Mycobacterium ulcerans putative regulatory protein 0.012 0.0178 0.6687
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.0267 0.037
Leishmania major hypothetical protein, conserved 0.0074 0.0087 0.1397
Brugia malayi hypothetical protein 0.0033 0.0005 0.0006
Onchocerca volvulus 0.4131 0.8199 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0059 0.0057 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.0011
Trichomonas vaginalis chromobox protein, putative 0.0117 0.0173 0.021
Loa Loa (eye worm) BRM protein 0.0046 0.0032 0.0043
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0202 0.0344 0.0343
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0046 0.0031 0.0043
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0012 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0604 0.1146 0.1146
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Onchocerca volvulus 0.0313 0.0566 0.069
Onchocerca volvulus Cathepsin L homolog 0.0035 0.001 0.0011
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0439 0.0816 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Trypanosoma brucei polo-like protein kinase 0.0105 0.015 0.2547
Leishmania major DNA-binding protein, putative,predicted bromodomain protein 0.0046 0.0032 0.0395
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0312 0.0562 0.0562
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0033 0.004
Loa Loa (eye worm) hypothetical protein 0.0117 0.0173 0.0239
Onchocerca volvulus 0.0035 0.0009 0.0011
Plasmodium falciparum phosphodiesterase delta, putative 0.0046 0.0031 0.0884
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0522 0.0982 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0087 0.0106
Trypanosoma brucei ISWI complex protein 0.0252 0.0443 0.7846
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0161 0.0261 1
Toxoplasma gondii aldehyde dehydrogenase 0.0122 0.0183 0.1792
Loa Loa (eye worm) hypothetical protein 0.0632 0.1203 0.1671
Schistosoma mansoni hypothetical protein 0.0243 0.0425 0.0425
Echinococcus granulosus Zinc finger DBF type 0.0035 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0161 0.0261 0.0362
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0439 0.0816 0.0816
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Brugia malayi Hypothetical C28H8.9 in chromosome III 0.0035 0.0009 0.0012
Entamoeba histolytica hypothetical protein 0.0036 0.0012 0.0033
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0012 0.0014
Onchocerca volvulus 0.0439 0.0816 0.0995
Trichomonas vaginalis hypothetical protein 0.0117 0.0173 0.021
Schistosoma mansoni lipoxygenase 0.0059 0.0057 0.0057
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0402
Onchocerca volvulus 0.0074 0.0087 0.0106
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.0061 0.0061
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0061 0.2041
Echinococcus granulosus lamin dm0 0.0168 0.0275 0.0274
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0117 0.0173 0.0172
Schistosoma mansoni tar DNA-binding protein 0.1438 0.2815 0.2815
Schistosoma mansoni requim req/dpf2 0.0035 0.0009 0.0009
Schistosoma mansoni cytochrome P450 0.0036 0.0012 0.0011
Schistosoma mansoni cpg binding protein 0.0097 0.0134 0.0134
Schistosoma mansoni hypothetical protein 0.034 0.0619 0.0618
Trichomonas vaginalis bromodomain containing protein, putative 0.0046 0.0032 0.0039
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0243 0.0425 0.0425
Schistosoma mansoni Smad4 0.0084 0.0106 0.0106
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0393 0.0725 0.0724
Trypanosoma cruzi ISWI complex protein 0.0252 0.0443 0.7846
Brugia malayi acetyltransferase, GNAT family protein 0.0335 0.0609 0.0845
Echinococcus multilocularis tar DNA binding protein 0.1438 0.2815 0.2815
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0055 0.0049 0.0068
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0161 0.0261 0.026
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0041 0.0021 0.0209
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0046 0.0031 0.0402
Brugia malayi beta-lactamase family protein 0.0074 0.0087 0.012
Plasmodium vivax bromodomain protein, putative 0.0046 0.0032 0.023
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0439 0.0816 0.1134
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0012 0.0049
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.016 0.026 0.9965
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0994 0.1927 0.1927
Echinococcus multilocularis muscleblind protein 1 0.0169 0.0277 0.0276
Toxoplasma gondii ABC1 family protein 0.0074 0.0087 0.0802
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0439 0.0816 0.0816
Schistosoma mansoni hypothetical protein 0.0046 0.0032 0.0031
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0099 0.0138 0.0191
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0012 0.0049
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0009
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0439 0.0816 0.1134
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Plasmodium falciparum phosphodiesterase gamma, putative 0.0046 0.0031 0.0884
Loa Loa (eye worm) hypothetical protein 0.0165 0.0269 0.0373
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0058 0.0071
Loa Loa (eye worm) cytochrome P450 family protein 0.0123 0.0185 0.0256
Brugia malayi MH1 domain containing protein 0.0084 0.0106 0.0147
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0439 0.0816 0.1134
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0884
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0055 0.005 0.1533
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0035 0.0008 0.0008
Schistosoma mansoni serine/threonine protein kinase 0.006 0.0058 0.0058
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0312 0.0562 0.0686
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0236 0.0412 0.0572
Trichomonas vaginalis esterase, putative 0.0074 0.0087 0.0106
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Brugia malayi Intermediate filament tail domain containing protein 0.0168 0.0275 0.0381
Echinococcus multilocularis cpg binding protein 0.0097 0.0134 0.0134
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0312 0.0562 0.0562
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0014 0.0017
Echinococcus multilocularis peptidase Clp (S14 family) 0.0105 0.015 0.015
Brugia malayi SET domain containing protein 0.0056 0.005 0.0069
Echinococcus multilocularis inositol monophosphatase 1 0.0082 0.0104 0.0104
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.001 0.0009
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0117 0.0173 0.3
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Onchocerca volvulus 0.1004 0.1947 0.2374
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0208 0.36
Brugia malayi PHD-finger family protein 0.0061 0.0061 0.0085
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0046 0.0031 0.0043
Schistosoma mansoni nAChR subunit 0.0439 0.0816 0.0816
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0041 0.058
Entamoeba histolytica hypothetical protein 0.0117 0.0173 0.3
Trypanosoma brucei glucosidase, putative 0.0036 0.0012 0.0049
Loa Loa (eye worm) CXXC zinc finger family protein 0.0062 0.0064 0.0088
Toxoplasma gondii histone acetyltransferase TAF1/250 0.0046 0.0032 0.0233
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0344 0.0477
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0031 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0124 0.0188 0.0229
Plasmodium falciparum GAF domain-related protein, putative 0.012 0.0178 0.6721
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) heterochromatin protein 1 0.0713 0.1365 0.1897
Brugia malayi hypothetical protein 0.0202 0.0344 0.0477
Brugia malayi STE20-like kinase MST 0.0237 0.0413 0.0574
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0046 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.0074 0.0087 0.012
Plasmodium vivax hypothetical protein, conserved 0.0117 0.0173 0.1679
Brugia malayi bromodomain containing protein 0.0046 0.0032 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Schistosoma mansoni zinc finger protein 0.0333 0.0605 0.0605
Brugia malayi MH2 domain containing protein 0.0084 0.0106 0.0147
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0057 0.0052 0.0786
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0082 0.0104 0.2174
Schistosoma mansoni acetylcholine receptor subunit beta 0.0202 0.0344 0.0343
Brugia malayi Inositol-1 0.0082 0.0104 0.0144
Trichomonas vaginalis hypothetical protein 0.0046 0.0032 0.0039
Toxoplasma gondii bromodomain-containing protein 0.0046 0.0032 0.0233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0046 0.0031 0.0043
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Schistosoma mansoni nAChR subunit 0.0439 0.0816 0.0816
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Onchocerca volvulus 0.0056 0.005 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.015 0.0183
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0117 0.0173 0.021
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0009 0.0003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0033 0.0429
Echinococcus multilocularis zinc finger protein 0.0333 0.0605 0.0605
Schistosoma mansoni myst-related protein 0.0039 0.0017 0.0016
Plasmodium vivax serine/threonine-specific protein kinase, putative 0.0109 0.0158 0.1528
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.006 0.0058 0.0885
Schistosoma mansoni ste20-related kinase 0.0183 0.0305 0.0305
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0117 0.0173 0.6496
Echinococcus granulosus lysine specific demethylase 5B 0.0035 0.0009 0.0009
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0117 0.0173 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.04 0.0739 0.0901
Loa Loa (eye worm) histone methyltransferase 0.0038 0.0016 0.0022
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.015 0.0183
Entamoeba histolytica bromodomain-containing protein 0.0046 0.0032 0.0402
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.015 0.0183
Echinococcus granulosus methyl CpG binding domain protein 2 0.0281 0.0501 0.05
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) acetyltransferase 0.0335 0.0609 0.0845
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.001 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Onchocerca volvulus 0.0035 0.001 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0243 0.0425 0.059
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0881 0.17 0.17
Echinococcus granulosus TAF3 RNA polymerase II TATA box binding protein 0.0035 0.0009 0.0009
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0046 0.0031 0.0031
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Brugia malayi jmjC domain containing protein 0.02 0.0339 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.015 0.0183
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0105 0.015 0.1585
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0439 0.0816 0.0816
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Loa Loa (eye worm) TAR-binding protein 0.1438 0.2815 0.3911
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trichomonas vaginalis inhibitor of growth, putative 0.0035 0.0009 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.047 0.0573
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Brugia malayi Bromodomain containing protein 0.0638 0.1215 0.1688
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0193 0.0325 0.0324
Schistosoma mansoni smad 0.0084 0.0106 0.0106
Trypanosoma cruzi ISWI complex protein 0.0252 0.0443 0.7846
Brugia malayi hypothetical protein 0.0123 0.0186 0.0257
Echinococcus granulosus PHD and RING finger domain containing protein 1 0.0035 0.0009 0.0009
Onchocerca volvulus 0.0236 0.0412 0.0502
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0033 0.0429
Echinococcus granulosus peptidase Clp S14 family 0.0105 0.015 0.015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Loa Loa (eye worm) bromodomain containing protein 0.0046 0.0032 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Leishmania major hypothetical protein, conserved 0.0046 0.0032 0.0395
Brugia malayi Cytochrome P450 family protein 0.0056 0.0051 0.0071
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0087 0.3019
Schistosoma mansoni hypothetical protein 0.0525 0.0989 0.0989
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.0061 0.0084
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0881 0.17 0.2362
Schistosoma mansoni chromobox protein 0.0713 0.1365 0.1365
Schistosoma mansoni PHD zinc finger protein XAP135-related 0.0035 0.0009 0.0009
Loa Loa (eye worm) bromodomain containing protein 0.0298 0.0535 0.0743
Echinococcus multilocularis lamin 0.0168 0.0275 0.0274
Onchocerca volvulus 0.0035 0.001 0.0011
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Schistosoma mansoni serine/threonine protein kinase 0.0105 0.015 0.015
Loa Loa (eye worm) ctsf protein 0.0035 0.001 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0522 0.0982 0.0982
Schistosoma mansoni neurotransmitter gated ion channel 0.0236 0.0412 0.0411
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0312 0.0562 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.0061 0.0929
Entamoeba histolytica serine/threonine protein kinase, putative 0.0105 0.015 0.2585
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.0046 0.0032 0.0402
Loa Loa (eye worm) hypothetical protein 0.0204 0.0348 0.0483
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Toxoplasma gondii SWI2/SNF2 Brahma-like putative 0.0046 0.0032 0.0233
Brugia malayi PHD-finger family protein 0.0035 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0117 0.0173 0.0239
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0183 0.6894
Schistosoma mansoni hypothetical protein 0.0312 0.0562 0.0562
Echinococcus multilocularis musashi 0.0168 0.0275 0.0274
Schistosoma mansoni jumonji/arid domain-containing protein 0.0109 0.0157 0.0157
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0768 0.1475 0.2049
Echinococcus granulosus glycine receptor subunit beta 0.0439 0.0816 0.0816
Trichomonas vaginalis inositol monophosphatase, putative 0.0082 0.0104 0.0127
Brugia malayi PHD-finger family protein 0.0055 0.0049 0.0068
Echinococcus multilocularis phd finger protein 10 0.0035 0.0009 0.0009
Brugia malayi polybromodomain protein 0.0046 0.0032 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Echinococcus multilocularis mothers against decapentaplegic 6 0.0037 0.0014 0.0013
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0046 0.0032 0.023
Brugia malayi PHD-finger family protein 0.0421 0.0781 0.1085
Schistosoma mansoni hypothetical protein 0.0243 0.0425 0.0425
Echinococcus granulosus histone acetyltransferase KAT2B 0.0126 0.0191 0.0191
Onchocerca volvulus 0.0439 0.0816 0.0995
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0126 0.0191 0.1869
Plasmodium falciparum zinc finger protein, putative 0.0039 0.0017 0.0303
Echinococcus multilocularis glycine receptor subunit beta 0.0439 0.0816 0.0816
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0131 0.0201 0.0245
Echinococcus granulosus PHD finger protein 14 0.0035 0.0009 0.0009
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.006 0.0058 0.008
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.0061 0.006
Schistosoma mansoni tar DNA-binding protein 0.1438 0.2815 0.2815
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0031 0.0402
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0152 0.0242 0.0242
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0087 0.012
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0639 0.1216 0.1215
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0009 0.0003
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0393 0.0725 0.0724
Brugia malayi beta-lactamase family protein 0.0074 0.0087 0.012
Echinococcus granulosus tar DNA binding protein 0.1438 0.2815 0.2815
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0881 0.17 0.17
Brugia malayi RNA binding protein 0.1438 0.2815 0.3911
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0061 0.0085
Echinococcus multilocularis chromobox protein 1 0.0713 0.1365 0.1365
Brugia malayi Cytochrome P450 family protein 0.0036 0.0012 0.0016
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0375 0.0689 0.0688
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.0011
Trypanosoma cruzi bromodomain factor 2 protein 0.0046 0.0032 0.0406
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0472 0.0883 1
Onchocerca volvulus 0.0035 0.0009 0.0011
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0161 0.0261 1
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0439 0.0816 0.0816
Loa Loa (eye worm) hypothetical protein 0.0105 0.0149 0.0206
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0439 0.0816 0.1134
Onchocerca volvulus Serine\/threonine kinase homolog 0.0105 0.015 0.0182
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0021 0.0103
Loa Loa (eye worm) hypothetical protein 0.0243 0.0425 0.059
Brugia malayi Bromodomain containing protein 0.0046 0.0032 0.0043
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0033 0.0032
Schistosoma mansoni neurotransmitter gated ion channel 0.0202 0.0344 0.0343
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0051 0.0765
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0087 0.0862
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Echinococcus granulosus GPCR family 2 0.0243 0.0425 0.0425
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0087 0.0862
Loa Loa (eye worm) LGC-31 protein 0.0439 0.0816 0.1134
Schistosoma mansoni intermediate filament proteins 0.0168 0.0275 0.0274
Echinococcus granulosus chromobox protein 2 0.0117 0.0173 0.0172
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0312 0.0562 0.0686
Loa Loa (eye worm) hypothetical protein 0.0347 0.0632 0.0878
Trichomonas vaginalis set domain proteins, putative 0.4131 0.8199 1
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Echinococcus granulosus polybromo 1 0.0046 0.0032 0.0031
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0074 0.0087 0.086
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0046 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0117 0.0173 0.021
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0208 0.36
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0131 0.0201 0.0245
Loa Loa (eye worm) hypothetical protein 0.1165 0.2268 0.3151
Schistosoma mansoni hypothetical protein 0.041 0.0759 0.0758
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.0109 0.0109
Schistosoma mansoni chromobox protein 0.0117 0.0173 0.0172
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.1004 0.1947 0.1947
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Echinococcus granulosus CREB binding protein 0.0046 0.0032 0.0031
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0046 0.0031 0.0038
Schistosoma mansoni phd finger protein 0.0046 0.0032 0.0031
Plasmodium vivax phosphodiesterase gamma, putative 0.0046 0.0031 0.0228
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0161 0.0261 0.026
Brugia malayi cytoplasmic intermediate filament protein 0.009 0.0119 0.0165
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0439 0.0816 0.0816
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0014 0.0073
Brugia malayi hypothetical protein 0.0176 0.0291 0.0404
Echinococcus multilocularis chromobox protein 1 0.0713 0.1365 0.1365
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0013
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0193 0.0325 0.0451
Brugia malayi MH2 domain containing protein 0.1226 0.2391 0.3323
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.0188 0.0229
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Toxoplasma gondii hypothetical protein 0.0265 0.047 0.4734
Loa Loa (eye worm) hypothetical protein 0.0313 0.0566 0.0786
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0152 0.0243 0.0242
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0243 0.0425 0.0425
Brugia malayi MH2 domain containing protein 0.0084 0.0106 0.0147
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni tar DNA-binding protein 0.1438 0.2815 0.2815
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Brugia malayi MH1 domain containing protein 0.0084 0.0106 0.0147
Loa Loa (eye worm) hypothetical protein 0.0227 0.0393 0.0546
Onchocerca volvulus 0.1004 0.1947 0.2374
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0012 0.0031
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0041 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0036 0.0012 0.0047
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0046 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0046 0.0032 0.0039
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0082 0.0104 0.1716
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0117 0.0173 0.3
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0439 0.0816 0.1134
Onchocerca volvulus Cell death protein 3 homolog 0.0044 0.0027 0.0032
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0046 0.0031 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0046 0.0056
Echinococcus granulosus transcription initiation factor TFIID subunit 1 0.0046 0.0032 0.0031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0074 0.0087 0.3013
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0019 0.0023
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.001 0.0009
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0117 0.0173 0.021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0325 0.0324
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0061 0.0538
Onchocerca volvulus 0.0236 0.0412 0.0502
Schistosoma mansoni smad 0.0037 0.0014 0.0013
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0105 0.015 0.555
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.006 0.0058 0.0885
Echinococcus multilocularis snurportin 1 0.0312 0.0562 0.0562
Echinococcus multilocularis lysine specific demethylase 5B 0.0035 0.0009 0.0009
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Schistosoma mansoni jumonji/arid domain-containing protein 0.0109 0.0157 0.0157
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.0267 0.0267
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0012 0.0011
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0033 0.0429
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0084 0.0106 0.0106
Trypanosoma brucei Bromodomain, putative 0.0046 0.0032 0.0406
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.006 0.0058 0.0885
Trypanosoma cruzi cruzipain precursor, putative 0.0135 0.0208 0.36
Brugia malayi Valyl-tRNA synthetase 0.0117 0.0173 0.0239
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0803 0.1544 0.1544
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0267 0.0267
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Echinococcus granulosus cytochrome P450 2K1 0.0036 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Schistosoma mansoni CREB-binding protein 2 0.0046 0.0032 0.0031
Brugia malayi excitatory GABA receptor EXP-1A 0.0439 0.0816 0.1134
Schistosoma mansoni polybromo-1 0.0046 0.0032 0.0031
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni methyl-cpg binding protein mbd 0.0281 0.0501 0.05
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0087 0.0113 0.0138
Brugia malayi Bromodomain containing protein 0.0046 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Brugia malayi hypothetical protein 0.0202 0.0344 0.0477
Brugia malayi hypothetical protein 0.0488 0.0914 0.127
Schistosoma mansoni acetylcholine receptor-related 0.0202 0.0344 0.0343
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.0061 0.0084
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.001 0.0024
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0183 0.0183
Mycobacterium tuberculosis Conserved protein 0.0074 0.0087 0.0862
Schistosoma mansoni phd finger protein 0.0035 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.0061 0.0559
Entamoeba histolytica hypothetical protein 0.0036 0.0012 0.0033
Onchocerca volvulus Huntingtin homolog 0.0123 0.0186 0.0226
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Schistosoma mansoni hypothetical protein 0.0351 0.0641 0.064
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0033 0.0032
Toxoplasma gondii bromodomain-containing protein 0.0046 0.0032 0.0233
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0768 0.1475 0.2049
Giardia lamblia GTOR 0.0047 0.0033 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Echinococcus granulosus glycine receptor subunit alpha 1 0.0439 0.0816 0.0816
Loa Loa (eye worm) PDE1B protein 0.0046 0.0031 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.0011
Toxoplasma gondii SWI2/SNF2-containing PHD finger protein 0.0035 0.0009 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0117 0.0173 0.0172
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Loa Loa (eye worm) helicase 0.0117 0.0173 0.0239
Leishmania major hypothetical protein, conserved 0.0252 0.0443 0.7844
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0082 0.0104 0.3707
Echinococcus multilocularis protein kinase C binding protein 1 0.0046 0.0032 0.0031
Mycobacterium tuberculosis Conserved protein 0.0074 0.0087 0.0862
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0036 0.0012 0.0047
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.001 0.0009
Loa Loa (eye worm) hypothetical protein 0.0074 0.0087 0.012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0243 0.0425 0.0425
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni helicase 0.0046 0.0032 0.0031
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0439 0.0816 0.1134
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Entamoeba histolytica hypothetical protein 0.0117 0.0173 0.3
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0803 0.1544 0.1544
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0283 0.0505 0.0616
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0439 0.0816 0.0816
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0008 0.0008
Leishmania major hypothetical protein, conserved 0.0041 0.0021 0.0199
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0046 0.0031 0.0402
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0375 0.0689 0.0688
Echinococcus granulosus fetal alzheimer antigen falz 0.0375 0.0689 0.0688
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0105 0.015 0.0208
Echinococcus multilocularis neuropeptide receptor A26 0.1012 0.1962 0.1962
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis STE family protein kinase 0.0109 0.0158 0.0193
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0057 0.0052 0.0782
Trichomonas vaginalis STE family protein kinase 0.0109 0.0158 0.0193
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0046 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Echinococcus granulosus uro adherence factor A 0.0035 0.0009 0.0009
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0087 0.0862
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0081 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Loa Loa (eye worm) hypothetical protein 0.0117 0.0173 0.0239
Loa Loa (eye worm) hypothetical protein 0.0117 0.0173 0.0239
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0117 0.0173 0.1681
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0057 0.0052 0.0786
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0014 0.0017
Loa Loa (eye worm) hypothetical protein 0.0881 0.17 0.2362
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0439 0.0816 0.1134
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.0031 0.0402
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0439 0.0816 0.0816
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0058 0.0885
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Giardia lamblia Kinase, STE STE20 0.0057 0.0052 0.0404
Entamoeba histolytica hypothetical protein 0.0236 0.0412 0.741
Loa Loa (eye worm) hypothetical protein 0.0078 0.0095 0.0131
Entamoeba histolytica ankyrin repeat protein, putative 0.0046 0.0032 0.0402
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0439 0.0816 0.1134
Brugia malayi hypothetical protein 0.0202 0.0344 0.0477
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Schistosoma mansoni kinase 0.0055 0.0048 0.0048
Loa Loa (eye worm) fibroinase 0.0035 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0193 0.0325 0.0324
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.009 0.0119 0.0165
Loa Loa (eye worm) hypothetical protein 0.0051 0.0041 0.0057
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0105 0.015 0.2539
Brugia malayi PHD-finger family protein 0.0035 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0439 0.0816 0.0816
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0009 0.0009
Plasmodium vivax hypothetical protein, conserved 0.012 0.0178 0.1737
Loa Loa (eye worm) MH2 domain-containing protein 0.0084 0.0106 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Echinococcus granulosus phd finger protein 12 0.0035 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0087 0.0799
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0202 0.0344 0.0477
Onchocerca volvulus Putative nachr subunit 0.0881 0.17 0.2073
Loa Loa (eye worm) hypothetical protein 0.0081 0.0101 0.014
Loa Loa (eye worm) hypothetical protein 0.0117 0.0173 0.0239
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0033 0.0426
Leishmania major hypothetical protein, conserved 0.0051 0.0041 0.057
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0087 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0312 0.0562 0.0686
Onchocerca volvulus 0.0035 0.0009 0.0011
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Onchocerca volvulus 0.0168 0.0275 0.0335
Brugia malayi Calcitonin receptor-like protein seb-1 0.0768 0.1475 0.2049
Schistosoma mansoni tar DNA-binding protein 0.1438 0.2815 0.2815
Schistosoma mansoni inositol monophosphatase 0.0082 0.0104 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0031 0.0038
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0126 0.0191 0.1872
Leishmania major cathepsin L-like protease 0.0135 0.0208 0.3593
Toxoplasma gondii histone lysine methyltransferase SET1 0.0184 0.0306 0.3057
Brugia malayi hypothetical protein 0.0117 0.0173 0.0239
Brugia malayi follicle stimulating hormone receptor 0.1283 0.2505 0.348
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0131 0.0201 0.0245
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.001 0.0009
Brugia malayi hypothetical protein 0.0202 0.0344 0.0477
Schistosoma mansoni transcription initiation factor tfiid 0.0046 0.0032 0.0031
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0041 0.1275
Entamoeba histolytica hypothetical protein 0.0036 0.0012 0.0033
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0439 0.0816 0.1134
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0087 0.0113 0.0138
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.0061 0.0061
Loa Loa (eye worm) Smad1 0.0084 0.0106 0.0147
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.015 0.2547
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.001 0.0009
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0439 0.0816 0.0816
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0122 0.0183 0.0183
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0012 0.0014
Brugia malayi Bromodomain associated family protein 0.0035 0.0009 0.0012
Plasmodium falciparum bromodomain protein 1 0.0046 0.0032 0.0892
Onchocerca volvulus 0.0095 0.0129 0.0157
Mycobacterium leprae Probable lipase LipE 0.0074 0.0087 0.3019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0057 0.0052 0.0782
Trypanosoma cruzi cysteine peptidase, putative 0.0135 0.0208 0.36
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0439 0.0816 0.0816
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0087 0.1406
Echinococcus multilocularis glycine receptor subunit beta 0.0439 0.0816 0.0816
Onchocerca volvulus 0.0046 0.0032 0.0038
Onchocerca volvulus 0.0202 0.0344 0.0419
Echinococcus granulosus mixed lineage leukemia protein mll 0.0035 0.0008 0.0008
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.1004 0.1947 0.1947
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0046 0.0031 0.0031
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0202 0.0344 0.0477
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0439 0.0816 0.1134
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0131 0.0201 0.0245
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0087 0.0862
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.0552 1
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0158 0.0157
Echinococcus multilocularis cysteine protease 0.0035 0.001 0.0009
Schistosoma mansoni phd finger protein 0.0035 0.0009 0.0009
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0122 0.0183 0.3144
Trypanosoma cruzi polo-like protein kinase, putative 0.0105 0.015 0.2547
Loa Loa (eye worm) hypothetical protein 0.0176 0.0291 0.0404
Echinococcus granulosus neuropeptide receptor A26 0.1012 0.1962 0.1962
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni inositol monophosphatase 0.0082 0.0104 0.0104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Trypanosoma cruzi Bromodomain, putative 0.0046 0.0032 0.0406
Schistosoma mansoni zinc finger protein 0.0252 0.0443 0.0443
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0087 0.0862
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.015 0.0183
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Echinococcus granulosus bromodomain containing protein 8 0.0046 0.0032 0.0031
Schistosoma mansoni alpha glucosidase 0.0036 0.0012 0.0011
Brugia malayi Cation transporter family protein 0.0439 0.0816 0.1134
Echinococcus multilocularis CREB binding protein 0.0046 0.0032 0.0031
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0312 0.0562 0.0686
Onchocerca volvulus 0.0035 0.0009 0.0011
Schistosoma mansoni nAChR subunit 0.0439 0.0816 0.0816
Brugia malayi Cation transporter family protein 0.1004 0.1947 0.2705
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0258 0.0455 0.0632
Brugia malayi Cell death protein 3 precursor 0.0044 0.0027 0.0037
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0258 0.0455 0.0455
Echinococcus granulosus glycine receptor subunit alpha 1 0.0439 0.0816 0.0816
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Echinococcus granulosus jumonji domain containing protein 0.0085 0.0109 0.0109
Trypanosoma brucei GAF domain/TIP41-like family, putative 0.0041 0.0021 0.0209
Schistosoma mansoni nAChR subunit 0.0202 0.0344 0.0343
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0046 0.0031 0.0031
Onchocerca volvulus Brd8 homolog 0.0046 0.0032 0.0038
Mycobacterium ulcerans hypothetical protein 0.0074 0.0087 0.3019
Trypanosoma cruzi Bromodomain factor 1 0.0046 0.0032 0.0406
Echinococcus granulosus neuropeptide s receptor 0.1012 0.1962 0.1962
Leishmania major hypothetical protein, conserved,predicted bromodomain protein 0.0046 0.0032 0.0395
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0009 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0161 0.0261 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Schistosoma mansoni alpha-glucosidase 0.0141 0.0221 0.0221
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0439 0.0816 0.0816
Brugia malayi MH2 domain containing protein 0.0037 0.0014 0.0019
Trichomonas vaginalis chromobox protein, putative 0.0713 0.1365 0.1665
Trichomonas vaginalis chromobox protein, putative 0.043 0.0799 0.0975
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0202 0.0344 0.0343
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0046 0.0031 0.0038
Brugia malayi beta-lactamase 0.0074 0.0087 0.012
Loa Loa (eye worm) hypothetical protein 0.0169 0.0277 0.0384
Leishmania major hypothetical protein, conserved 0.0046 0.0032 0.0395
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.0267 0.037
Schistosoma mansoni cpg binding protein 0.0062 0.0064 0.0064
Plasmodium falciparum protein kinase, putative 0.0109 0.0158 0.5912
Echinococcus multilocularis uro adherence factor A 0.0035 0.0009 0.0009
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0352 0.0644 0.0785
Entamoeba histolytica bromodomain-containing protein 0.0046 0.0032 0.0402
Brugia malayi Muscleblind-like protein 0.0169 0.0277 0.0384
Echinococcus multilocularis Chromobox protein 3 0.0117 0.0173 0.0172
Echinococcus multilocularis 0.0036 0.0012 0.0011
Loa Loa (eye worm) GABA receptor subunit 0.0236 0.0412 0.0572
Mycobacterium ulcerans lipase LipD 0.0074 0.0087 0.3019
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0312 0.0562 0.0686
Plasmodium vivax vivapain-2 0.0035 0.001 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0161 0.0261 0.2587
Echinococcus granulosus peregrin 0.0107 0.0154 0.0153
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.015 0.0239 0.9115
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0046 0.0031 0.0402
Loa Loa (eye worm) hypothetical protein 0.0074 0.0087 0.012
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0046 0.0031 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0014 0.0017
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0439 0.0816 0.0816
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0117 0.0173 0.3
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0081 0.0102 0.0141
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.015 0.0183
Echinococcus granulosus TGF beta signal transducer SmadC 0.0084 0.0106 0.0106
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Echinococcus multilocularis tumor protein p63 0.1397 0.2732 0.2732
Brugia malayi Protein kinase domain containing protein 0.0169 0.0276 0.0383
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Leishmania major cytochrome p450-like protein 0.0036 0.0012 0.0036
Schistosoma mansoni hypothetical protein 0.0252 0.0443 0.0443
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.0061 0.006
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0152 0.0243 0.0242
Brugia malayi Cytochrome P450 family protein 0.0056 0.0051 0.0071
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0126 0.0191 0.1872
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.0061 0.0528
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Echinococcus granulosus tumor protein p63 0.1397 0.2732 0.2732
Echinococcus granulosus nAChR subunit 0.0236 0.0412 0.0411
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0123 0.0186 0.0226
Brugia malayi polybromodomain protein 0.0046 0.0032 0.0043
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.015 0.0239 0.9115
Echinococcus multilocularis PHD and RING finger domain containing protein 1 0.0035 0.0009 0.0009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0059 0.0057 0.0057
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.016 0.026 0.2846
Echinococcus multilocularis Zinc finger, DBF type 0.0035 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0087 0.0106
Echinococcus granulosus phd finger protein 10 0.0035 0.0009 0.0009
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0183 0.6894
Echinococcus multilocularis serine:threonine protein kinase 3 0.0237 0.0413 0.0413
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0055 0.0049 0.0048
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0082 0.0104 0.0127
Schistosoma mansoni chromobox protein 0.0713 0.1365 0.1365
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.0074 0.0087 0.012
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0046 0.0056
Trichomonas vaginalis Heterochromatin protein, putative 0.0117 0.0173 0.021
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0051 0.0071
Mycobacterium ulcerans putative regulatory protein 0.012 0.0178 0.6687
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0081 0.0101 0.0101
Echinococcus granulosus Smad4 0.0084 0.0106 0.0106
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0061 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Schistosoma mansoni lamin 0.0168 0.0275 0.0274
Brugia malayi MAP kinase sur-1 0.006 0.0058 0.008
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0014 0.0084
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.006 0.0058 0.0885
Echinococcus multilocularis mitogen activated protein kinase 3 0.006 0.0058 0.0058
Onchocerca volvulus 0.0117 0.0173 0.021
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Echinococcus multilocularis Smad4 0.0084 0.0106 0.0106
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1283 0.2505 0.348
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.001 0.0024
Echinococcus multilocularis polybromo 1 0.0046 0.0032 0.0031
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.0061 0.0935
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0012 0.0014
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.001 0.0013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0002 0.0002
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0169 0.0276 0.0383
Plasmodium falciparum heterochromatin protein 1 0.0117 0.0173 0.6496
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Brugia malayi SET domain containing protein 0.0137 0.0214 0.0296
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0161 0.0261 1
Giardia lamblia Transcription regulatory protein SNF2 0.0046 0.0032 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0335 0.0609 0.0608
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0522 0.0982 0.0982
Echinococcus multilocularis global transcription activator snf2l2 0.0046 0.0032 0.0031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0131 0.0201 0.0245
Leishmania major hypothetical protein, conserved 0.0046 0.0031 0.0392
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0058 0.0071
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0881 0.17 0.2362
Echinococcus granulosus chromobox protein 1 0.0713 0.1365 0.1365
Schistosoma mansoni hepatitis B virus X associated protein hbxa 0.0035 0.0009 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0193 0.0325 0.0451
Echinococcus multilocularis PHD finger protein 14 0.0035 0.0009 0.0009
Brugia malayi F/Y-rich N-terminus family protein 0.009 0.0118 0.0164
Echinococcus granulosus cathepsin l1 0.0035 0.001 0.0009
Loa Loa (eye worm) RNA binding protein 0.1438 0.2815 0.3911
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0057 0.0052 0.0782
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Loa Loa (eye worm) hypothetical protein 0.0094 0.0128 0.0177
Trypanosoma cruzi GAF domain/TIP41-like family, putative 0.0041 0.0021 0.0209
Schistosoma mansoni nAChR subunit 0.0439 0.0816 0.0816
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.001 0.0013
Loa Loa (eye worm) CBP-B 0.0046 0.0032 0.0043
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0012 0.0011
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0082 0.0104 0.0127
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0439 0.0816 0.1134
Loa Loa (eye worm) MH1 domain-containing protein 0.0084 0.0106 0.0147
Loa Loa (eye worm) MH2 domain-containing protein 0.0037 0.0014 0.0019
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0122 0.0183 0.0183
Schistosoma mansoni ap endonuclease 0.0061 0.0061 0.006
Toxoplasma gondii hypothetical protein 0.0046 0.0032 0.0233
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Onchocerca volvulus 0.0035 0.001 0.0011
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Entamoeba histolytica bromodomain-containing protein 0.0046 0.0032 0.0402
Schistosoma mansoni hypothetical protein 0.0036 0.0012 0.0011
Schistosoma mansoni eyes absent homolog 0.0094 0.0128 0.0127
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0803 0.1544 0.1544
Echinococcus granulosus chromobox protein 1 0.0713 0.1365 0.1365
Schistosoma mansoni zinc finger protein 0.0035 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0193 0.0325 0.0324
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0046 0.0031 0.0038
Echinococcus multilocularis caspase 2 0.0044 0.0027 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Loa Loa (eye worm) CHromoDomain protein family member 0.0152 0.0243 0.0337
Trypanosoma brucei bromodomain factor 2 protein, putative 0.0046 0.0032 0.0406
Mycobacterium tuberculosis Conserved protein 0.0074 0.0087 0.0862
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0161 0.0261 0.5
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0087 0.3019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0056 0.0051 0.1595
Echinococcus granulosus mothers against decapentaplegic 2 0.0037 0.0014 0.0013
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0117 0.0173 0.1681
Schistosoma mansoni tar DNA-binding protein 0.1438 0.2815 0.2815
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0046 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0014 0.0019
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0202 0.0344 0.0343
Schistosoma mansoni survival motor neuron protein 0.0099 0.0138 0.0138
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0046 0.0031 0.0402
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0012 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.1438 0.2815 0.3911
Brugia malayi ATPase, AAA family protein 0.0046 0.0032 0.0043
Echinococcus granulosus lysine specific demethylase 5A 0.0109 0.0157 0.0157
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0046 0.0031 0.0031
Trichomonas vaginalis chromobox protein, putative 0.0713 0.1365 0.1665
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trypanosoma brucei Bromodomain, putative 0.0046 0.0032 0.0406
Trypanosoma cruzi Bromodomain, putative 0.0046 0.0032 0.0406
Brugia malayi serine/threonine-protein kinase plk-2 0.0105 0.015 0.0208
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0312 0.0562 0.0686
Echinococcus granulosus global transcription activator snf2l2 0.0046 0.0032 0.0031
Echinococcus granulosus mothers against decapentaplegic 5 0.0084 0.0106 0.0106
Schistosoma mansoni cellular tumor antigen P53 0.0204 0.0348 0.0348
Echinococcus granulosus PH interacting protein 0.0046 0.0032 0.0031
Echinococcus granulosus inositol monophosphatase 1 0.0082 0.0104 0.0104
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0087 0.0106
Brugia malayi Pre-SET motif family protein 0.0522 0.0982 0.1365
Giardia lamblia Fructose-bisphosphate aldolase 0.0307 0.0552 1
Leishmania major cAMP-specific phosphodiesterase, putative 0.0046 0.0031 0.0392
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0178 0.0217
Trichomonas vaginalis chromobox protein, putative 0.0117 0.0173 0.021
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0033 0.0426
Echinococcus granulosus dnaJ subfamily B 0.041 0.0759 0.0758
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0033 0.0045
Loa Loa (eye worm) hypothetical protein 0.0117 0.0173 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Trichomonas vaginalis bromodomain containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0014 0.0017
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0061 0.0535
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0125 0.0189 0.0188
Trypanosoma cruzi major cysteine proteinase, putative 0.0106 0.0151 0.2559
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0009 0.0003
Plasmodium falciparum histone acetyltransferase GCN5 0.008 0.0099 0.3557
Onchocerca volvulus 0.0035 0.001 0.0011
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0192 0.0323 0.5676
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0236 0.0412 0.0411
Loa Loa (eye worm) hypothetical protein 0.1004 0.1947 0.2705
Schistosoma mansoni caspase-7 (C14 family) 0.0044 0.0027 0.0026
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0202 0.0344 0.0477
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Plasmodium vivax SET domain protein, putative 0.0522 0.0982 1
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0009
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0122 0.0183 0.1969
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Loa Loa (eye worm) inositol-1 0.0082 0.0104 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0032 0.023
Echinococcus granulosus bromodomain containing 2 0.0046 0.0032 0.0031
Onchocerca volvulus 0.0035 0.001 0.0011
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0036 0.0012 0.0047
Mycobacterium ulcerans aldehyde dehydrogenase 0.0122 0.0183 0.6894
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0439 0.0816 0.1134
Trichomonas vaginalis bromodomain containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0439 0.0816 0.1134
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0352 0.0644 0.0785
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Onchocerca volvulus 0.0062 0.0064 0.0078
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0312 0.0562 0.0686
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0325 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.0011
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0768 0.1475 0.2049
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trypanosoma brucei Bromodomain factor 1 0.0046 0.0032 0.0406
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.006 0.0058 0.0875
Brugia malayi Smad1 0.0084 0.0106 0.0147
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0402
Loa Loa (eye worm) transcription factor SMAD2 0.1226 0.2391 0.3323
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0312 0.0562 1
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0031 0.0402
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0335 0.0609 0.0608
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0881 0.17 0.17
Giardia lamblia PHD finger protein 15 0.0061 0.0061 0.0574
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0344 0.0477
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Brugia malayi latrophilin 2 splice variant baaae 0.0525 0.0989 0.1374
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0046 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0678 0.1295 0.1799
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Schistosoma mansoni ap endonuclease 0.0061 0.0061 0.006
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.0011
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0046 0.0031 0.0031
Trichomonas vaginalis bromodomain-containing protein 4, brd4, putative 0.0046 0.0032 0.0039
Brugia malayi RNA recognition motif domain containing protein 0.1438 0.2815 0.3911
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.0011
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0161 0.0261 0.2584
Echinococcus granulosus cpg binding protein 0.0097 0.0134 0.0134
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0012 0.0039
Onchocerca volvulus Cathepsin L homolog 0.0035 0.001 0.0011
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0439 0.0816 0.0816
Trichomonas vaginalis hypothetical protein 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Schistosoma mansoni dpf3 0.0035 0.0009 0.0009
Trichomonas vaginalis bromodomain containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0131 0.0201 0.0245
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0439 0.0816 0.1134
Echinococcus granulosus zinc finger protein 0.0333 0.0605 0.0605
Toxoplasma gondii bromodomain-containing protein 0.0046 0.0032 0.0233
Trichomonas vaginalis STE family protein kinase 0.0057 0.0052 0.0064
Echinococcus multilocularis phd finger protein 12 0.0035 0.0009 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0031 0.0402
Echinococcus granulosus intermediate filament protein 0.0168 0.0275 0.0274
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.0502 0.0943 0.9593
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0161 0.0261 1
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni CREB-binding protein 1 (SmCBP1) 0.0046 0.0032 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0033 0.004
Schistosoma mansoni hypothetical protein 0.0117 0.0173 0.0172
Brugia malayi Bromodomain containing protein 0.0046 0.0032 0.0043
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0047 0.0034 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Brugia malayi Heterochromatin protein 1 0.0713 0.1365 0.1897
Loa Loa (eye worm) hypothetical protein 0.0123 0.0186 0.0257
Echinococcus granulosus snurportin 1 0.0312 0.0562 0.0562
Loa Loa (eye worm) intermediate filament protein 0.0168 0.0275 0.0381
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0087 0.012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0243 0.0425 0.0425
Loa Loa (eye worm) hypothetical protein 0.0488 0.0914 0.127
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0125 0.0189 0.0262
Loa Loa (eye worm) hypothetical protein 0.0525 0.0989 0.1374
Schistosoma mansoni myst-related protein 0.0039 0.0017 0.0016
Echinococcus granulosus caspase 2 0.0044 0.0027 0.0026
Schistosoma mansoni hypothetical protein 0.0351 0.0641 0.064
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0082 0.0104 0.1716
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.001 0.0009
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0012 0.0038
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.02 0.0339 0.0339
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Echinococcus multilocularis survival motor neuron protein 1 0.0488 0.0914 0.0914
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0033 0.0429
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0166 0.027 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trypanosoma cruzi Bromodomain, putative 0.0046 0.0032 0.0406
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0038
Schistosoma mansoni nAChR subunit 0.0439 0.0816 0.0816
Brugia malayi Bromodomain containing protein 0.0107 0.0154 0.0213
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0046 0.0031 0.0031
Schistosoma mansoni lamin 0.0168 0.0275 0.0274
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0161 0.0261 0.5
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.0061 0.1958
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0013
Schistosoma mansoni chromobox protein 0.0117 0.0173 0.0172
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0041 0.0332
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0592 0.1122 0.1122
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0281 0.0501 0.05
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0592 0.1122 0.1122
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0046 0.0031 0.0402
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0031 0.0402
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0055 0.0048 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0014 0.0017
Echinococcus multilocularis mitogen activated protein kinase 0.006 0.0058 0.0058
Echinococcus granulosus CREB binding protein 0.0046 0.0032 0.0031
Toxoplasma gondii bromodomain-containing protein 0.0046 0.0032 0.0233
Echinococcus granulosus muscleblind protein 0.0169 0.0277 0.0276
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0117 0.0173 0.6496
Echinococcus granulosus survival motor neuron protein 1 0.0488 0.0914 0.0914
Echinococcus multilocularis peregrin 0.0107 0.0154 0.0153
Loa Loa (eye worm) hypothetical protein 0.0169 0.0277 0.0384
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0202 0.0344 0.0477
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4123 0.8183 0.8183
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0131 0.0201 0.0245
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.0061 0.0929
Brugia malayi Bromodomain containing protein 0.0046 0.0032 0.0043
Brugia malayi Protein kinase domain containing protein 0.0125 0.0189 0.0262
Brugia malayi Bromodomain containing protein 0.1246 0.2431 0.3377
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0037 0.0014 0.0016
Brugia malayi RNA, U transporter 1 0.0083 0.0105 0.0145
Plasmodium vivax SET domain containing protein 0.0067 0.0073 0.0652
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0061 0.0538
Loa Loa (eye worm) hypothetical protein 0.0044 0.0027 0.0037
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0105 0.015 0.1585
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.0061 0.0559
Echinococcus granulosus Bromodomain containing protein 0.0046 0.0032 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Brugia malayi CXXC zinc finger family protein 0.0062 0.0064 0.0088
Giardia lamblia Histone acetyltransferase GCN5 0.008 0.0099 0.1291
Onchocerca volvulus 0.0099 0.0138 0.0168
Brugia malayi CHD4 protein 0.0152 0.0243 0.0337
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0087 0.0106
Giardia lamblia Kinase, putative 0.0046 0.0032 0.0004
Echinococcus multilocularis neuropeptide s receptor 0.1012 0.1962 0.1962
Onchocerca volvulus 0.0046 0.0032 0.0038
Trypanosoma brucei protein kinase, putative 0.006 0.0058 0.0885
Leishmania major cathepsin L-like protease 0.0135 0.0208 0.3593
Schistosoma mansoni peptidase Clp (S14 family) 0.0161 0.0261 0.026
Schistosoma mansoni hypothetical protein 0.0036 0.0012 0.0011
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.0061 0.0929
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.006 0.0058 0.0875
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0105 0.015 0.015
Schistosoma mansoni hypothetical protein 0.0243 0.0425 0.0425
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0046 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0074 0.0087 0.012
Loa Loa (eye worm) hypothetical protein 0.04 0.0739 0.1026
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Onchocerca volvulus 0.0204 0.0348 0.0424
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0439 0.0816 0.0816
Trypanosoma brucei AAA ATPase, putative 0.0046 0.0032 0.0406
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0283 0.0505 0.0616
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0038 0.0016 0.0016
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0307 0.0552 0.0674
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0192 0.0323 0.0394
Loa Loa (eye worm) hypothetical protein 0.0074 0.0087 0.012
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0439 0.0816 0.1134
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Onchocerca volvulus 0.0439 0.0816 0.0995
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Echinococcus multilocularis chromobox protein 2 0.0117 0.0173 0.0172
Echinococcus multilocularis histone acetyltransferase myst3 0.0035 0.0009 0.0009
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0439 0.0816 0.1134
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Onchocerca volvulus 0.0202 0.0344 0.0419
Brugia malayi hypothetical protein 0.0035 0.0009 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0202 0.0344 0.0477
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Loa Loa (eye worm) hypothetical protein 0.0046 0.0031 0.0043
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0202 0.0344 0.0477
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.0051 0.0071
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.0061 0.0074
Plasmodium vivax vivapain-2 0.0035 0.001 0.0006
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0439 0.0816 0.1134
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0038
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0131 0.0201 0.0245
Trichomonas vaginalis chromobox protein, putative 0.0117 0.0173 0.021
Loa Loa (eye worm) STE/STE20/YSK protein kinase 0.0109 0.0158 0.0219
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0046 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0046 0.0032 0.0031
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0166 0.027 0.033
Echinococcus granulosus glycine receptor subunit beta 0.0439 0.0816 0.0816
Giardia lamblia Hypothetical protein 0.0046 0.0032 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0037 0.0014 0.0019
Echinococcus multilocularis 0.0046 0.0032 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Echinococcus multilocularis smad 0.0084 0.0106 0.0106
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0013
Mycobacterium ulcerans beta-lactamase 0.0074 0.0087 0.3019
Echinococcus multilocularis Chromo domain 0.0117 0.0173 0.0172
Echinococcus granulosus serine:threonine protein kinase 3 0.0237 0.0413 0.0413
Onchocerca volvulus 0.0035 0.001 0.0011
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0202 0.0344 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Toxoplasma gondii cytochrome p450 superfamily protein 0.0036 0.0012 0.003
Brugia malayi MH1 domain containing protein 0.0046 0.0032 0.0043
Leishmania major cytochrome p450-like protein 0.0056 0.0051 0.0755
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0013
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0312 0.0562 0.0562
Loa Loa (eye worm) hypothetical protein 0.0802 0.1542 0.2143
Loa Loa (eye worm) nuclear factor I 0.0046 0.0032 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.006 0.0058 0.0506
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0884
Onchocerca volvulus Heterochromatin protein 1 homolog 0.04 0.0739 0.09
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0126 0.019 0.019
Loa Loa (eye worm) PHD-finger family protein 0.034 0.0619 0.0859
Echinococcus granulosus lamin 0.0168 0.0275 0.0274
Brugia malayi Bromodomain containing protein 0.0046 0.0032 0.0043
Plasmodium vivax bromodomain protein, putative 0.0046 0.0032 0.023
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Brugia malayi MH1 domain containing protein 0.0046 0.0032 0.0043
Leishmania major protein kinase, putative 0.0057 0.0052 0.0772
Echinococcus multilocularis histone acetyltransferase myst4 0.0035 0.0009 0.0009
Toxoplasma gondii hypothetical protein 0.0055 0.005 0.0422
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0087 0.0087
Echinococcus granulosus histone acetyltransferase myst4 0.0035 0.0009 0.0009
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0236 0.0412 0.0572
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0032 0.0406
Trichomonas vaginalis bromodomain containing protein, putative 0.0046 0.0032 0.0039
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0439 0.0816 0.1134
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.001 0.0009
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0036 0.0012 0.0036
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0267 0.0267
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0046 0.0031 0.0031
Brugia malayi Bromodomain containing protein 0.0046 0.0032 0.0043
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Entamoeba histolytica bromodomain-containing protein 0.0046 0.0032 0.0402
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0041 0.0329
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0033 0.0419
Schistosoma mansoni hypothetical protein 0.0046 0.0032 0.0031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni aldehyde dehydrogenase 0.0122 0.0183 0.0183
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0046 0.0031 0.0031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trypanosoma cruzi Bromodomain, putative 0.0046 0.0032 0.0406
Echinococcus granulosus mitogen activated protein kinase 3 0.006 0.0058 0.0058
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0312 0.0562 0.0686
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0881 0.17 0.17
Onchocerca volvulus 0.0639 0.1216 0.1483
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0033 0.0419
Onchocerca volvulus 0.0046 0.0032 0.0038
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Echinococcus multilocularis TAF3 RNA polymerase II, TATA box binding protein 0.0035 0.0009 0.0009
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0046 0.0031 0.0884
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.047 0.0573
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0055 0.005 0.162
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0046 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0046 0.0032 0.0031
Trypanosoma brucei cytochrome P450, putative 0.0056 0.0051 0.0765
Toxoplasma gondii cathepsin CPL 0.0035 0.001 0.0009
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0881 0.17 0.17
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.001 0.0011
Brugia malayi hypothetical protein 0.0094 0.0128 0.0177
Brugia malayi TAR-binding protein 0.1438 0.2815 0.3911
Brugia malayi M-phase phosphoprotein, mpp8 0.0117 0.0173 0.0239
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0135 0.0208 0.36
Schistosoma mansoni zinc finger protein 0.0035 0.0009 0.0009
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0236 0.0412 0.0411
Brugia malayi chromobox protein homolog 3 0.04 0.0739 0.1026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0166 0.027 0.033
Brugia malayi Bromodomain containing protein 0.0046 0.0032 0.0043
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0012 0.0039
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.363 0.7196 1
Loa Loa (eye worm) F/Y-rich family protein 0.0035 0.0009 0.0012
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0994 0.1927 0.1927
Giardia lamblia Kinase, PLK 0.0105 0.015 0.2277
Loa Loa (eye worm) CYP4Cod1 0.0056 0.0051 0.0071
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0192 0.0323 0.0394
Echinococcus granulosus remodeling and spacing factor 1 0.0035 0.0009 0.0009
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0312 0.0562 1
Trichomonas vaginalis bromodomain and PHD finger-containing protein, putative 0.0046 0.0032 0.0039
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0236 0.0412 0.0572
Echinococcus granulosus Chromobox protein 3 0.0117 0.0173 0.0172
Loa Loa (eye worm) hypothetical protein 0.0078 0.0095 0.0131
Loa Loa (eye worm) cytochrome P450 0.0036 0.0012 0.0016
Echinococcus granulosus histone acetyltransferase KAT2B 0.0288 0.0514 0.0514
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0061 0.0061 0.0085
Trichomonas vaginalis bromodomain-containing protein, putative 0.0126 0.0191 0.0233
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0117 0.0173 0.0172
Schistosoma mansoni Smad4 0.0037 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0009
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0082 0.0104 0.1707
Trichomonas vaginalis conserved hypothetical protein 0.0117 0.0173 0.021
Echinococcus multilocularis serine threonine protein kinase 0.0109 0.0158 0.0157
Loa Loa (eye worm) hypothetical protein 0.0258 0.0455 0.0632
Schistosoma mansoni bromodomain containing 0.0046 0.0032 0.0031
Brugia malayi Associated with TFs and helicases family protein 0.0117 0.0173 0.0239
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Loa Loa (eye worm) hypothetical protein 0.0803 0.1544 0.2145
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0038
Echinococcus multilocularis PH interacting protein 0.0046 0.0032 0.0031
Schistosoma mansoni cpg binding protein 0.0097 0.0134 0.0134
Loa Loa (eye worm) MH2 domain-containing protein 0.1226 0.2391 0.3323
Trichomonas vaginalis conserved hypothetical protein 0.0352 0.0644 0.0785
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0161 0.0261 0.2587
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0055 0.0049 0.0048
Loa Loa (eye worm) hypothetical protein 0.0202 0.0344 0.0477
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0117 0.0173 0.0172
Loa Loa (eye worm) hypothetical protein 0.0094 0.0128 0.0177
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0117 0.0173 0.1681
Plasmodium falciparum bromodomain protein 2, putative 0.0046 0.0032 0.0892
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0312 0.0562 1
Echinococcus multilocularis mothers against decapentaplegic 5 0.0084 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0046 0.0031 0.0043
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0035 0.0009 0.0009
Echinococcus multilocularis bromodomain containing protein 8 0.0046 0.0032 0.0031
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0012 0.0011
Schistosoma mansoni nAChR subunit 0.0202 0.0344 0.0343
Onchocerca volvulus 0.0035 0.001 0.0011
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0046 0.0031 0.0031
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.0061 0.0061
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0009 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0058 0.0071
Echinococcus granulosus mitogen activated protein kinase 0.006 0.0058 0.0058
Toxoplasma gondii AP2 domain transcription factor AP2VIIa-7 0.0035 0.0009 0.0003
Giardia lamblia Hypothetical protein 0.0046 0.0032 0.0004
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0087 0.0087
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.001 0.0013
Schistosoma mansoni methyl-cpg binding protein mbd 0.0281 0.0501 0.05
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0012 0.0016
Onchocerca volvulus Bromodomain adjacent to zinc finger domain protein 1A homolog 0.0046 0.0032 0.0038
Schistosoma mansoni Smad4 0.0037 0.0014 0.0013
Entamoeba histolytica protein kinase, putative 0.0109 0.0158 0.273
Brugia malayi hypothetical protein 0.0035 0.0009 0.0012
Echinococcus granulosus histone acetyltransferase myst3 0.0035 0.0009 0.0009
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0312 0.0562 0.0686
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0046 0.0031 0.0043
Echinococcus multilocularis lamin dm0 0.0168 0.0275 0.0274
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.0061 0.0919
Plasmodium falciparum phd finger protein, putative 0.0061 0.0061 0.2072
Echinococcus multilocularis mothers against decapentaplegic 2 0.0037 0.0014 0.0013
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0012 0.0011
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Leishmania major cytochrome p450-like protein 0.0036 0.0012 0.0036
Schistosoma mansoni hypothetical protein 0.0243 0.0425 0.0425
Schistosoma mansoni hypothetical protein 0.0099 0.0138 0.0138
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0055 0.005 0.0419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0041 0.058
Trypanosoma cruzi cytochrome P450, putative 0.0056 0.0051 0.0765
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0117 0.0173 0.0239
Toxoplasma gondii exonuclease III APE 0.0061 0.0061 0.053
Brugia malayi mothers against decapentaplegic homolog 3 0.0037 0.0014 0.0019
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0228
Echinococcus granulosus glycine receptor subunit alpha 1 0.0439 0.0816 0.0816
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0161 0.0261 0.4195
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0031 0.0402
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0046 0.0031 0.0031
Echinococcus granulosus protein kinase C binding protein 1 0.0046 0.0032 0.0031
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Toxoplasma gondii GAF domain-containing protein 0.012 0.0178 0.1739
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0439 0.0816 0.0816
Brugia malayi BRM protein 0.0046 0.0032 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0265 0.047 0.0573
Onchocerca volvulus 0.0117 0.0173 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0009 0.0011
Schistosoma mansoni bromodomain-containing protein 3 brd3 0.0046 0.0032 0.0031
Schistosoma mansoni neurotransmitter gated ion channel 0.0202 0.0344 0.0343
Schistosoma mansoni bromodomain containing protein 0.0081 0.0102 0.0101
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0126 0.0191 0.0233
Echinococcus multilocularis muscleblind protein 0.0169 0.0277 0.0276
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Echinococcus multilocularis Bromodomain containing protein 0.0046 0.0032 0.0031
Brugia malayi Cathepsin L-like precursor 0.0035 0.001 0.0013
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Schistosoma mansoni myst histone acetyltransferase 0.0035 0.0009 0.0009
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0047 0.0034 0.0041
Echinococcus granulosus histone lysine methyltransferase setb 0.0803 0.1544 0.1544
Entamoeba histolytica hypothetical protein 0.0117 0.0173 0.3
Onchocerca volvulus Huntingtin homolog 0.0123 0.0186 0.0226
Echinococcus multilocularis bromodomain containing 2 0.0046 0.0032 0.0031
Brugia malayi TAZ zinc finger family protein 0.0046 0.0032 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0041 0.1275
Trypanosoma cruzi hypothetical protein, conserved 0.0046 0.0031 0.0402
Giardia lamblia Kinase, CMGC MAPK 0.006 0.0058 0.0513
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.02 0.0339 0.0339
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0312 0.0562 0.0686
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0033 0.0032
Entamoeba histolytica bromodomain-containing protein 0.0046 0.0032 0.0402
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0012 0.0016
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0087 0.3019
Loa Loa (eye worm) jmjC domain-containing protein 0.0109 0.0157 0.0218
Echinococcus multilocularis dnaJ subfamily B 0.041 0.0759 0.0758
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0012 0.0014
Onchocerca volvulus 0.0176 0.0291 0.0355
Trypanosoma brucei Bromodomain, putative 0.0046 0.0032 0.0406
Trypanosoma cruzi Bromodomain, putative 0.0046 0.0032 0.0406
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Brugia malayi Protein cec-1. 0.0117 0.0173 0.0239
Trichomonas vaginalis chromobox protein, putative 0.043 0.0799 0.0975
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0123 0.0185 0.3178
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Schistosoma mansoni smad1 5 8 and 0.0084 0.0106 0.0106
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0084 0.0106 0.0106
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0193 0.0325 0.0324
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.015 0.0239 0.2603
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Loa Loa (eye worm) cysteine protease 0.0035 0.001 0.0013
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0012 0.0014
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0312 0.0562 0.078
Onchocerca volvulus 0.1004 0.1947 0.2374
Loa Loa (eye worm) ACC-1 protein 0.0439 0.0816 0.1134
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0046 0.0032 0.0039
Schistosoma mansoni smad1 5 8 and 0.0084 0.0106 0.0106
Brugia malayi Cytochrome P450 family protein 0.0123 0.0185 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Onchocerca volvulus 0.0168 0.0275 0.0335
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0046 0.0031 0.0392
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Brugia malayi Probable ClpP-like protease 0.0161 0.0261 0.0362
Schistosoma mansoni SET domain protein 0.0056 0.005 0.005
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0046 0.0032 0.0031
Trichomonas vaginalis lymphoid specific helicase, putative 0.0046 0.0032 0.0039
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0046 0.0031 0.0031
Onchocerca volvulus Cathepsin F homolog 0.0035 0.001 0.0011
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0009
Entamoeba histolytica acetyltransferase, GNAT family 0.008 0.0099 0.1638
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.012 0.0178 0.191
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0193 0.0325 0.0324
Brugia malayi PHD-finger family protein 0.0035 0.0009 0.0012
Brugia malayi Pre-SET motif family protein 0.363 0.7196 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.001 0.0013
Loa Loa (eye worm) beta-lactamase 0.0074 0.0087 0.012
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0881 0.17 0.17
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0046 0.0031 0.0031
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Schistosoma mansoni smad1 5 8 and 0.0084 0.0106 0.0106
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0033 0.004
Echinococcus multilocularis Bromodomain containing protein 0.0046 0.0032 0.0031
Toxoplasma gondii hypothetical protein 0.012 0.0178 0.1739
Loa Loa (eye worm) hypothetical protein 0.1004 0.1947 0.2705
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0202 0.0344 0.0343
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0604 0.1146 0.1146
Brugia malayi hypothetical protein 0.0202 0.0344 0.0477
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0046 0.0031 0.0884
Schistosoma mansoni nAChR subunit 0.0439 0.0816 0.0816
Brugia malayi cytochrome P450 0.0036 0.0012 0.0016
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0237 0.0413 0.0574
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0393 0.0725 0.1006
Onchocerca volvulus Heterochromatin protein 1 homolog 0.043 0.0799 0.0974
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0439 0.0816 0.0816
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0082 0.0104 0.1738
Loa Loa (eye worm) hypothetical protein 0.0046 0.0032 0.0043
Trypanosoma cruzi bromodomain-containing protein 3 0.0046 0.0032 0.0406
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0046 0.0032 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0087 0.1406
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Echinococcus multilocularis cysteine protease 0.0035 0.001 0.0009
Leishmania major hypothetical protein, conserved 0.0046 0.0031 0.0392
Schistosoma mansoni bromodomain containing protein 0.1053 0.2045 0.2044
Echinococcus multilocularis remodeling and spacing factor 1 0.0035 0.0009 0.0009
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0105 0.015 0.015
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0046 0.0032 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0236 0.0412 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Brugia malayi hypothetical protein 0.0051 0.0041 0.0057
Echinococcus multilocularis geminin 0.0351 0.0641 0.064
Trichomonas vaginalis CMGC family protein kinase 0.006 0.0058 0.0071
Loa Loa (eye worm) hypothetical protein 0.0439 0.0816 0.1134
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0087 0.0862
Echinococcus multilocularis nAChR subunit 0.0236 0.0412 0.0411
Echinococcus granulosus mothers against decapentaplegic 6 0.0037 0.0014 0.0013
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0439 0.0816 0.1134
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0501 0.0941 0.0941
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0038
Brugia malayi Latrophilin receptor protein 2 0.0243 0.0425 0.059
Entamoeba histolytica hypothetical protein 0.0039 0.0017 0.0129
Entamoeba histolytica bromodomain-containing protein 0.0046 0.0032 0.0402
Loa Loa (eye worm) ACC-1 protein 0.0439 0.0816 0.1134
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0046 0.0031 0.0402
Plasmodium falciparum bromodomain protein, putative 0.0046 0.0032 0.0892
Schistosoma mansoni hypothetical protein 0.0061 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0117 0.0173 0.1679
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.0191 0.0265
Echinococcus granulosus Bromodomain containing protein 0.0046 0.0032 0.0031
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0352 0.0644 0.0785
Leishmania major cathepsin L-like protease 0.0135 0.0208 0.3593
Brugia malayi jmjC domain containing protein 0.0109 0.0157 0.0218
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0168 0.0275 0.0381
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0152 0.0243 0.0242
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0012 0.0014
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0312 0.0562 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0087 0.0087
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0033 0.0045
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Brugia malayi hypothetical protein 0.0036 0.0012 0.0015
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0032 0.0039
Echinococcus granulosus nAChR subunit 0.0439 0.0816 0.0816
Schistosoma mansoni alpha-glucosidase 0.0141 0.0221 0.0221
Brugia malayi Cation transporter family protein 0.0439 0.0816 0.1134
Echinococcus multilocularis myosin iiia 0.0057 0.0052 0.0052
Onchocerca volvulus 0.0202 0.0344 0.0419
Treponema pallidum fructose-bisphosphate aldolase 0.0307 0.0552 1
Onchocerca volvulus 0.0074 0.0087 0.0106
Plasmodium vivax heterochromatin protein 1, putative 0.0117 0.0173 0.1679
Trichomonas vaginalis CAMK family protein kinase 0.0105 0.015 0.0183
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0082 0.0104 0.0978
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0046 0.0031 0.0228
Schistosoma mansoni bromodomain containing protein 0.0046 0.0032 0.0031
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0012 0.0014
Schistosoma mansoni fyve-containing 0.0035 0.0009 0.0009
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0046 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.04 0.0739 0.0901
Onchocerca volvulus 0.0074 0.0087 0.0106
Entamoeba histolytica hypothetical protein 0.0036 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0012
Brugia malayi PHD-finger family protein 0.0035 0.0009 0.0012
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0307 0.0552 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0046 0.0031 0.0231
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0014 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Echinococcus multilocularis nAChR subunit 0.0439 0.0816 0.0816
Schistosoma mansoni jumonji domain containing protein 0.0159 0.0257 0.0257
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.0061 0.0211
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0038 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Loa Loa (eye worm) hypothetical protein 0.0123 0.0186 0.0257
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.001 0.0012
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0117 0.0173 0.0239
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0032 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.001 0.0012
Plasmodium vivax bromodomain protein, putative 0.0046 0.0032 0.023
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.0087 0.0087
Echinococcus granulosus smad 0.0084 0.0106 0.0106
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0035 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0009 0.0011
Loa Loa (eye worm) latrophilin receptor protein 2 0.0243 0.0425 0.059

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) > 20 uM Inhibition of Escherichia coli recombinant ribonuclease H after 30 mins by FRET quenching assay ChEMBL. 21489793

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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