Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0074 | 0.008 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0177 | 0.2059 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0235 | 0.2764 | 0.2971 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0074 | 0.0079 |
Echinococcus multilocularis | acetylcholinesterase | 0.0767 | 0.9303 | 0.9303 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0177 | 0.2059 | 0.2213 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0074 | 0.0079 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.013 | 0.147 | 0.7138 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0373 | 0.1812 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0074 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0074 | 0.008 |
Schistosoma mansoni | hypothetical protein | 0.0339 | 0.4039 | 0.4342 |
Brugia malayi | polk-prov protein | 0.0031 | 0.0253 | 0.0272 |
Echinococcus multilocularis | neuroligin | 0.013 | 0.147 | 0.147 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0014 | 0.0052 | 0.0056 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.013 | 0.147 | 0.7063 |
Echinococcus granulosus | replication factor c subunit 1 | 0.001 | 0.00000034704 | 0.00000037305 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0326 | 0.0326 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0074 | 0.0079 |
Echinococcus granulosus | acetylcholinesterase | 0.0767 | 0.9303 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.147 | 0.158 |
Onchocerca volvulus | 0.013 | 0.147 | 0.4095 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0499 | 0.0537 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.004 | 0.0373 | 0.2539 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0074 | 0.0074 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0074 | 0.008 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0074 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0253 | 0.0272 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0074 | 0.0074 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0177 | 0.2059 | 1 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0014 | 0.0052 | 0.0052 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0373 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0074 | 0.008 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0014 | 0.0052 | 0.1532 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0038 | 0.0339 | 0.0364 |
Echinococcus granulosus | acetylcholinesterase | 0.0767 | 0.9303 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0134 | 0.1521 | 0.1635 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0177 | 0.2059 | 0.2059 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.3589 | 0.3858 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.1666 | 0.1791 |
Loa Loa (eye worm) | hypothetical protein | 0.0767 | 0.9303 | 1 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.00000034704 | 0.0000023613 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.147 | 0.158 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.013 | 0.147 | 0.7063 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.147 | 0.158 |
Onchocerca volvulus | 0.013 | 0.147 | 0.4095 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.0339 | 1 |
Onchocerca volvulus | 0.013 | 0.147 | 0.4095 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0303 | 0.0325 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0339 | 0.2307 |
Toxoplasma gondii | exonuclease III APE | 0.0038 | 0.0339 | 0.1647 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0038 | 0.0339 | 0.0364 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0177 | 0.2059 | 0.2213 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0134 | 0.1521 | 0.1635 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0074 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0074 | 0.008 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0074 | 0.0079 |
Echinococcus granulosus | geminin | 0.0339 | 0.4039 | 0.4342 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0074 | 0.008 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0074 | 0.0079 |
Schistosoma mansoni | gliotactin | 0.013 | 0.147 | 0.158 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0038 | 0.0339 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0074 | 0.0074 |
Brugia malayi | Carboxylesterase family protein | 0.0767 | 0.9303 | 1 |
Echinococcus granulosus | neuroligin | 0.013 | 0.147 | 0.158 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0074 | 0.008 |
Onchocerca volvulus | 0.013 | 0.147 | 0.4095 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0132 | 0.3528 |
Brugia malayi | Smad1 | 0.0016 | 0.0074 | 0.0079 |
Echinococcus granulosus | BC026374 protein S09 family | 0.013 | 0.147 | 0.158 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.013 | 0.147 | 0.147 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0177 | 0.2059 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0074 | 0.008 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0074 | 0.008 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0038 | 0.0339 | 1 |
Echinococcus multilocularis | smad | 0.0016 | 0.0074 | 0.0074 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.1666 | 0.1791 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0034 | 0.0293 | 0.7864 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0038 | 0.0339 | 0.0339 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0074 | 0.0074 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0077 | 0.2073 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0339 | 0.9086 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0038 | 0.0339 | 0.143 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0326 | 0.0351 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.013 | 0.147 | 0.147 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.013 | 0.147 | 0.158 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.147 | 0.158 |
Schistosoma mansoni | DNA polymerase eta | 0.0014 | 0.0052 | 0.0056 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0077 | 0.2073 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.1666 | 0.1791 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0038 | 0.0339 | 0.9086 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0132 | 0.0397 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0177 | 0.2059 | 0.2213 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0038 | 0.0339 | 0.0364 |
Schistosoma mansoni | smad | 0.0016 | 0.0074 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0302 | 0.3589 | 0.3858 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.001 | 0.00000034704 | 0.00000034704 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0038 | 0.0339 | 0.1647 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0038 | 0.0339 | 0.143 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0074 | 0.0079 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0134 | 0.1521 | 0.1521 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0326 | 0.9622 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0014 | 0.0052 | 0.1392 |
Loa Loa (eye worm) | carboxylesterase | 0.0767 | 0.9303 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0339 | 0.0364 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0038 | 0.0339 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.1666 | 0.1666 |
Onchocerca volvulus | 0.0302 | 0.3589 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.147 | 0.158 |
Brugia malayi | Carboxylesterase family protein | 0.0767 | 0.9303 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0235 | 0.2764 | 0.2971 |
Echinococcus granulosus | dna polymerase eta | 0.0014 | 0.0052 | 0.0056 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0767 | 0.9303 | 0.9303 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.013 | 0.147 | 0.158 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0074 | 0.0074 |
Trypanosoma brucei | unspecified product | 0.0034 | 0.0293 | 0.7864 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.147 | 0.158 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0499 | 0.0537 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0014 | 0.0052 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0052 | 0.0056 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0326 | 0.9622 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0074 | 0.0079 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0303 | 0.0325 |
Loa Loa (eye worm) | carboxylesterase | 0.013 | 0.147 | 0.158 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0134 | 0.1521 | 0.1521 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0326 | 0.9622 |
Schistosoma mansoni | hypothetical protein | 0.0339 | 0.4039 | 0.4342 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0074 | 0.0079 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Echinococcus multilocularis | geminin | 0.0339 | 0.4039 | 0.4039 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0074 | 0.008 |
Echinococcus multilocularis | dna polymerase eta | 0.0014 | 0.0052 | 0.0052 |
Brugia malayi | hypothetical protein | 0.013 | 0.147 | 0.158 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0499 | 0.0537 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0074 | 0.0079 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0177 | 0.2059 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0177 | 0.2059 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.013 | 0.147 | 0.158 |
Toxoplasma gondii | ATPase, AAA family protein | 0.001 | 0.00000034704 | 0.0000016854 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0132 | 0.0397 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0014 | 0.0052 | 0.0056 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0038 | 0.0339 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0134 | 0.1521 | 0.1635 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0011 | 0.0011 | 0.0054 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0373 | 0.1812 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0038 | 0.0339 | 0.2307 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.013 | 0.147 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0235 | 0.2764 | 0.2971 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0132 | 0.0397 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0326 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0767 | 0.9303 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0014 | 0.0052 | 0.0056 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0014 | 0.0052 | 0.0056 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.013 | 0.147 | 0.158 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.013 | 0.147 | 0.158 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.1666 | 0.1791 |
Echinococcus granulosus | carboxylesterase 5A | 0.0767 | 0.9303 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.013 | 0.147 | 0.158 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0077 | 0.2073 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.013 | 0.147 | 0.147 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0134 | 0.1521 | 0.1635 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.147 | 0.158 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.013 | 0.147 | 0.7063 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0373 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.013 | 0.147 | 0.158 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0134 | 0.1521 | 0.1635 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.004 | 0.0373 | 0.2539 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0499 | 0.0537 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0767 | 0.9303 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0134 | 0.1521 | 0.1635 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.001 | 0.00000034704 | 0.0000023613 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0767 | 0.9303 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0177 | 0.2059 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0253 | 0.6769 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0038 | 0.0339 | 1 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0132 | 0.3882 |
Echinococcus multilocularis | acetylcholinesterase | 0.0767 | 0.9303 | 0.9303 |
Echinococcus granulosus | dna polymerase kappa | 0.004 | 0.0373 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.147 | 0.158 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0014 | 0.0052 | 0.0056 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0074 | 0.0079 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0074 | 0.0079 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0326 | 0.0351 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.001 | 0.00000034704 | 0.00000037305 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0038 | 0.0339 | 0.9086 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0074 | 0.0079 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.001 | 0.00000034704 | 0.0000023613 |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.147 | 0.158 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0303 | 0.0325 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0326 | 0.9622 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0074 | 0.0074 |
Echinococcus granulosus | smad | 0.0016 | 0.0074 | 0.0079 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.013 | 0.147 | 1 |
Onchocerca volvulus | 0.013 | 0.147 | 0.4095 | |
Brugia malayi | Carboxylesterase family protein | 0.013 | 0.147 | 0.158 |
Schistosoma mansoni | ap endonuclease | 0.0038 | 0.0339 | 0.0364 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0326 | 0.0351 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0134 | 0.1521 | 0.1635 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.1666 | 0.1666 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0373 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.004 | 0.0373 | 0.0373 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.013 | 0.147 | 0.158 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0253 | 0.6769 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0074 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.147 | 0.158 |
Schistosoma mansoni | acetylcholinesterase | 0.013 | 0.147 | 0.158 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0014 | 0.0052 | 0.1392 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 12 uM | Antifungal activity against Candida albicans ATCC 10231 after 18 to 20 hrs by microbroth dilution method | ChEMBL. | 21319749 |
MIC (functional) | = 12 uM | Antifungal activity against Saccharomyces cerevisiae after 18 to 20 hrs by microbroth dilution method | ChEMBL. | 21319749 |
MIC (functional) | > 48 uM | Antibacterial activity against Escherichia coli ATCC 25922 after 18 to 20 hrs by microbroth dilution method | ChEMBL. | 21319749 |
MIC (functional) | > 48 uM | Antibacterial activity against Escherichia coli D21 after 18 to 20 hrs by microbroth dilution method | ChEMBL. | 21319749 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.